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Domestic Animal Endocrinology, ISSN 0739-7240, 01/2020, Volume 70, p. 106377
Research on the effects of nutrient restriction in beef cows on fetal pancreatic development is limited. To address this, multiparous Angus-cross cows (n = 22)... 
Nutrient restriction | β cells | Fetal pancreas
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 10/2010, Volume 161, Issue 4, pp. 799 - 814
  BACKGROUND AND PURPOSE Quercetin lowers plasma glucose, normalizes glucose tolerance tests and preserves pancreatic [beta]-cell integrity in diabetic rats.... 
pancreatic β-cells | ERK1/2 | cell viability | quercetin | insulin secretion | diabetes | oxidative stress
Journal Article
Biochimica et biophysica acta. General subjects, 09/2019, pp. 129422 - 129422
Previous studies suggested that fibrillar human IAPP (hIAPP) is more likely to deposit in β-cells, resulting in β-cell injury. However, the changes in the... 
Index Medicus
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2016, Volume 789, pp. 354 - 361
Mosapride, a gastrointestinal prokinetic drug, is an agonist of 5-hydroxytryptamine (5-HT) receptor 4 that also reduces blood glucose. Whether 5-HT receptor is... 
Blood glucose | Mosapride | receptor | Prucalopride | 5-HT | Insulin | Islet β cells
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 10/2019, Volume 1865, Issue 10, pp. 2753 - 2764
In the setting of metabolic overload, chronic elevations of free fatty acids in blood and tissues are associated with pancreatic β-cell lipotoxicity and... 
β-Catenin | SCD1 | GPR40 | Islets adaptation | Lipotoxicity | Pancreatic β-cells | Index Medicus
Journal Article
Antioxidants and Redox Signaling, ISSN 1523-0864, 2019, Volume 30, Issue 4, pp. 560 - 576
Glucagon-like peptide-1 (GLP-1) increases intracellular Ca concentrations, resulting in insulin secretion from pancreatic β-cells through the sequential... 
carbon monoxide | pancreatic β-cells | nitric oxide | heme oxygenase 2 | Ca
Journal Article
Arquivo Brasileiro de Medicina Veterinaria e Zootecnia, ISSN 0102-0935, 11/2017, Volume 69, Issue 6, pp. 1466 - 1472
RESUMO O insulinoma é um tumor das células β do pâncreas, que têm a função de produzir e secretar insulina e, geralmente são malignos em cães. O presente... 
Hypoglycemia | Tumor | β cells | VETERINARY SCIENCES
Journal Article
Molecular Metabolism, ISSN 2212-8778, 09/2019, Volume 27, pp. S42 - S48
Pancreatic β-cells adapt to high metabolic demand by expanding their β-cell mass and/or enhancing insulin secretion to maintain glucose homeostasis. Type 2... 
Insulin resistance | Epigenomics | Epitranscriptomics | β-cells | Transcriptomics | Genomics
Journal Article
Cell Biochemistry and Biophysics, ISSN 1085-9195, 03/2009, Volume 53, Issue 2, pp. 65 - 74
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 01/2020, Volume 246, pp. 112214 - 112214
Medicinal herb L. (chicory) has been used traditionally for the treatment of various diseases, including diabetes. One of the promising therapeutic options to... 
Pancreatic β cells | Cichorium intybus L | Embryonal carcinoma stem cells | Medicinal herbs | C-peptide | PDX-1 | Index Medicus
Journal Article
Trends in genetics : TIG, ISSN 0168-9525, 6/2015, Volume 31, Issue 6, pp. 290 - 299
Insulin-producing β-cells within the pancreatic islet of Langerhans are responsible for maintaining glucose homeostasis; the loss or malfunction of β-cells... 
long noncoding RNAs | Pancreas | islet | β-cells | epigenetic
Journal Article
Biophysical chemistry, 08/2019, Volume 254, pp. 106247 - 106247
The β-cells dynamics is the regulator of insulin secretion in the pancreas, and its investigation is a central aspect in designing effective treatment... 
Index Medicus
Journal Article
International Journal of Molecular Medicine, ISSN 1107-3756, 12/2010, Volume 26, Issue 6, pp. 813 - 818
Journal Article
Molecular Metabolism, 03/2019, Volume 21, pp. 1 - 12
Background: The divalent cation Calcium (Ca ) regulates a wide range of processes in disparate cell types. Within insulin-producing β-cells, increases in... 
CaMK | CREB | β-cells | Calcineurin | Diabetes | Calmodulin | NFAT
Journal Article
Life Sciences, ISSN 0024-3205, 09/2019, Volume 233, pp. 116732 - 116732
Linderane, an important bioactive compound in Linderae, improved glucose and lipid metabolism in / mice. However, the effect of linderane on streptozotocin... 
Pancreatic islet β cells | Oxidative stress | Diabetes mellitus (DM) | Nrf2 signaling pathway | Linderane | p38 MAPK signaling pathway | Index Medicus
Journal Article
Toxicology, ISSN 0300-483X, 09/2019, Volume 425, pp. 152252 - 152252
Cadmium (Cd) is known to be ranked the 7 hazardous substance in the Substance Priority List by Agency for Toxic Substances and Disease Registry. The... 
c-Jun N-terminal kinase (JNK) | Cadmium | Intracellular calcium | β-cells | C/EBP homologous protein (CHOP) | Apoptosis | Index Medicus
Journal Article
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, ISSN 1015-8987, 2019, Volume 52, Issue 2, pp. 186 - 197
Mitochondria-targeted antioxidants such as mitoquinone (MitoQ) have demonstrated protective effects against oxidative damage in several diseases. The increase... 
ER stress | Pancreatic β cells | Oxidative stress | Mitochondrial dysfunction | MitoQ | Type 2 Diabetes | Index Medicus
Journal Article
Endocrine Journal, ISSN 0918-8959, 2015, Volume 62, Issue 1, pp. 37 - 51
MafA and MafB are basic leucine zipper transcription factors expressed in mature pancreatic β- and α-cells, respectively. MafA is not only an insulin gene... 
Kusabira Orange | MafB | β-cells | Reporter | MafA
Journal Article
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