X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
inhibitors (29) 29
β-lactams (29) 29
antibiotics (28) 28
β-lactam (26) 26
beta-lactams (25) 25
index medicus (25) 25
derivatives (24) 24
beta-lactam (22) 22
chemistry, organic (22) 22
chemistry, multidisciplinary (21) 21
β-lactam antibiotics (21) 21
asymmetric-synthesis (19) 19
staudinger reaction (19) 19
chemistry, medicinal (17) 17
design (16) 16
chemistry (15) 15
humans (15) 15
organic chemistry (15) 15
amides (14) 14
monocyclic beta-lactams (14) 14
antibacterial (13) 13
biochemistry & molecular biology (13) 13
imines (12) 12
pharmacology & pharmacy (11) 11
stereoselective-synthesis (11) 11
clavulanic acid (10) 10
anti-bacterial agents - pharmacology (9) 9
antimicrobial activity (9) 9
beta-lactam antibiotics (9) 9
building-blocks (9) 9
human-leukocyte elastase (9) 9
monocyclic β-lactams (9) 9
penicillin (9) 9
beta-lactams - chemistry (8) 8
biological activity (8) 8
biosynthesis (8) 8
cephalosporins (8) 8
chemistry/food science, general (8) 8
cycloaddition (8) 8
microbial sensitivity tests (8) 8
synthesis (8) 8
2-azetidinone (7) 7
animals (7) 7
anti-bacterial agents - chemistry (7) 7
azetidines - chemistry (7) 7
bacteria (7) 7
beta-lactams - chemical synthesis (7) 7
biochemistry, general (7) 7
chemical synthesis (7) 7
inorganic chemistry (7) 7
molecular structure (7) 7
stereoselectivity (7) 7
amino acids (6) 6
analytical chemistry (6) 6
anti-bacterial agents - biosynthesis (6) 6
anti-bacterial agents - chemical synthesis (6) 6
antimicrobial agents (6) 6
azetidin-2-ones (6) 6
beta-lactams - pharmacology (6) 6
biological-activity (6) 6
biomedicine (6) 6
biotechnology & applied microbiology (6) 6
drug resistance (6) 6
enzymes (6) 6
escherichia-coli (6) 6
models, molecular (6) 6
pharmacology/toxicology (6) 6
resistance (6) 6
vilsmeier reagent (6) 6
β-lactamase (6) 6
β‐lactams (6) 6
2-azetidinones (5) 5
acid (5) 5
acids (5) 5
beta-lactamase inhibitors (5) 5
cell biology (5) 5
crystal-structure (5) 5
gram-negative bacteria (5) 5
life sciences (5) 5
microbiology (5) 5
monocyclic β-lactam (5) 5
physical chemistry (5) 5
streptomyces-clavuligerus (5) 5
theoretical and computational chemistry (5) 5
anti-bacterial agents - therapeutic use (4) 4
antibacterial activity (4) 4
beta-lactamase (4) 4
biological evaluation (4) 4
carbapenems (4) 4
cholesterol absorption (4) 4
clavulanic acid - biosynthesis (4) 4
e coli (4) 4
efficient (4) 4
enzyme inhibitors - pharmacology (4) 4
imine (4) 4
in-vitro activity (4) 4
ketene (4) 4
ketenes (4) 4
lactam (4) 4
mechanism (4) 4
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Current Medicinal Chemistry, ISSN 0929-8673, 10/2011, Volume 18, Issue 28, pp. 4265 - 4283
Journal Article
Synthesis (Stuttgart), ISSN 0039-7881, 2016, Volume 48, Issue 23, pp. 4199 - 4206
Journal Article
Bulletin of the Korean Chemical Society, ISSN 0253-2964, 01/2013, Volume 34, Issue 1, pp. 121 - 127
New types of monocyclic beta-lactams constitute an important class of compounds due to their unique structures and natures... 
Isopropylthioazetidinone | Monocyclic β-lactams | T-Butylthioazetidinone | Degradation of penicillin | Penicillin | Monocyclic beta-lactams | ANTIBIOTICS | t-Butylthioazetidinone | RING | INHIBITORS | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Bulletin of the Korean Chemical Society, ISSN 0253-2964, 10/2014, Volume 35, Issue 10, pp. 2990 - 2994
The studies on design and synthesis of new monocyclic beta-lactam esters 4(R/S)-(1'-methoxycarbonylpropy12'(R/S)-thio)-3(R... 
Azetidinone | 3-mercaptobutanoate | Monocyclic β-lactams | Acetylthio | Monocyclic beta-lactams | ANTIBIOTICS | ACID | Azeticlinone | INHIBITORS | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Arkivoc, ISSN 1551-7004, 08/2015, Volume 2015, Issue 7, pp. 10 - 27
Journal Article
Monatshefte für Chemie - Chemical Monthly, ISSN 0026-9247, 6/2015, Volume 146, Issue 6, pp. 941 - 946
Journal Article
Archives of Toxicology, ISSN 0340-5761, 11/2017, Volume 91, Issue 11, pp. 3647 - 3662
BAL30072 is a new monocyclic β-lactam antibiotic under development which provides a therapeutic option for the treatment of severe infections caused by multi-drug-resistant Gram-negative bacteria... 
Biomedicine, general | Biomedicine | Environmental Health | Monocyclic β-lactams | Occupational Medicine/Industrial Medicine | Reactive oxygen species (ROS) | Glycolysis | Pharmacology/Toxicology | Mitochondrial toxicity | Hepatotoxicity | APOPTOSIS | CELLS | MITOCHONDRIA | TOXICITY | INDUCED LIVER-INJURY | PERMEABILITY TRANSITION | Monocyclic beta-lactams | METABOLISM | GLUTATHIONE | INFLAMMATION | TOXICOLOGY | EXPRESSION | Cell Survival - drug effects | Solute Carrier Organic Anion Transporter Family Member 1B3 - metabolism | Thiazoles - blood | Electron Transport - drug effects | Lipopolysaccharides - toxicity | Apoptosis - drug effects | Humans | Microsomes, Liver - metabolism | Monobactams - adverse effects | Male | Glycolysis - drug effects | Thiazoles - adverse effects | Hep G2 Cells | Kupffer Cells - drug effects | Monobactams - blood | Monobactams - toxicity | Thiazoles - toxicity | Chemical and Drug Induced Liver Injury - metabolism | Microsomes, Liver - drug effects | Adenosine Triphosphate - metabolism | Solute Carrier Organic Anion Transporter Family Member 1b1 - metabolism | Chemical and Drug Induced Liver Injury - pathology | Hepatocytes - drug effects | Reactive oxygen species | Toxicity | Liver | Transaminase | Amides | Hepatocellular carcinoma | Drug resistance | Electron transport chain | Mitochondria | Rodents | Bacteria | Membrane potential | Gram-negative bacteria | Inhibition | β-Lactam antibiotics | Rats | Oxygen consumption | Metabolism | Fatty acids | Antibiotics | Hepatocytes | N-Acetyl-L-cysteine | Electron transport | Apoptosis
Journal Article