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1. Full Text β-Lactamases and β-Lactamase Inhibitors in the 21st Century
by Tooke, Catherine L and Hinchliffe, Philip and Bragginton, Eilis C and Colenso, Charlotte K and Hirvonen, Viivi H.A and Takebayashi, Yuiko and Spencer, James
Journal of molecular biology, ISSN 0022-2836, 08/2019, Volume 431, Issue 18, pp. 3472 - 3500
carbapenemase | β-lactam | enzyme mechanism | antimicrobial resistance | metallo-β-lactamase | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Index Medicus | MBL, metallo-β-lactamase | SHV, sulfydryl variant | VIM, Verona imipenemase | PBP, penicillin-binding protein | NDM, New Delhi metallo-β-lactamase | TEM, Temoneira (β-lactamase) | molecular mechanics | DBO, diazabicyclooctane | OXA, oxacillinase | CTX-M, cefotaximase | KPC, Klebsiella pneumoniae carbapenemase | SBL, serine β-lactamase | ESBL, extended spectrum β-lactamase | SFX, serial femtosecond crystallography | MM, quantum mechanics | QM
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2. Full Text What remains against carbapenem-resistant Enterobacteriaceae? Evaluation of chloramphenicol, ciprofloxacin, colistin, fosfomycin, minocycline, nitrofurantoin, temocillin and tigecycline
by Livermore, David M and Warner, Marina and Mushtaq, Shazad and Doumith, Michel and Zhang, Jiancheng and Woodford, Neil
International journal of antimicrobial agents, ISSN 0924-8579, 2011, Volume 37, Issue 5, pp. 415 - 419
Infectious Disease | Carbapenemase | NDM β-lactamase | KPC β-lactamase | OXA-48 β-lactamase | VIM β-lactamase | Pharmacology & Pharmacy | Infectious Diseases | Life Sciences & Biomedicine | Microbiology | Science & Technology | Biological and medical sciences | Medical sciences | Pharmacology. Drug treatments | Antibiotics. Antiinfectious agents. Antiparasitic agents | Microbial Sensitivity Tests | Enterobacteriaceae - enzymology | beta-Lactam Resistance | Enterobacteriaceae Infections - microbiology | Humans | Enterobacteriaceae - drug effects | United Kingdom | Anti-Bacterial Agents - pharmacology | Bacterial Proteins - biosynthesis | Enterobacteriaceae - isolation & purification | beta-Lactamases - biosynthesis | RNA | Nitrofurantoin | Oxalic acid | Analysis | Minocycline | Beta lactamases | Chloramphenicol | Ciprofloxacin | Fosfomycin | Enzymes | Pneumonia | Bacterial pneumonia | Chemotherapy | Cancer | Index Medicus | Life Sciences | Microbiology and Parasitology
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3. Full Text Phenotypic detection of extended-spectrum β-lactamase production in Enterobacteriaceae: review and bench guide
by Drieux, L and Brossier, F and Sougakoff, W and Jarlier, V
Clinical microbiology and infection, ISSN 1198-743X, 01/2008, Volume 14, Issue 1, pp. 90 - 103
β-Lactamase | phenotypic detection | extended-spectrum β-lactamases | review | Enterobacteriaceae | extended‐spectrum β‐lactamases | β‐Lactamase | Extended-spectrum β-lactamases | Phenotypic detection | Review | Infectious Diseases | Life Sciences & Biomedicine | Microbiology | Science & Technology | Enterobacteriaceae - enzymology | Phenotype | beta-Lactamases - classification | Clavulanic Acid - pharmacology | Humans | Sensitivity and Specificity | Enterobacteriaceae - drug effects | Anti-Bacterial Agents - pharmacology | beta-Lactamases - biosynthesis | Cephalosporins - pharmacology | Microbial Sensitivity Tests - methods | Index Medicus
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4. Full Text Activity of aminoglycosides, including ACHN-490, against carbapenemresistant Enterobacteriaceae isolates
by Livermore, D.M and Mushtaq, S and Warner, M and Zhang, J.-C and Maharjan, S and Doumith, M and Woodford, N
Journal of antimicrobial chemotherapy, ISSN 0305-7453, 01/2011, Volume 66, Issue 1, pp. 48 - 53
NDM β-lactamase | Amikacin | KPC β-lactamase | Gentamicin | Isepamicin | Carbapenemase | Tobramycin
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5. Full Text An Improved Synthesis of CENTA, a Chromogenic Substrate for β-Lactamases
by Quotadamo, Antonio and Linciano, Pasquale and Davoli, Paolo and Tondi, Donatella and Costi, Maria Paola and Venturelli, Alberto
Synlett, ISSN 0936-5214, 10/2016, Volume 27, Issue 17, pp. 2447 - 2450
letter | synthesis | CENTA | β-lactamase kinetics | chromogenic substrate | β-lactamase detection
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6. Full Text Management of infections caused by extended-spectrum β-lactamase-producing Enterobacteriaceae: current evidence and future prospects
by Sheu, Chau-Chyun and Lin, Shang-Yi and Chang, Ya-Ting and Lee, Chun-Yuan and Chen, Yen-Hsu and Hsueh, Po-Ren
Expert review of anti-infective therapy, ISSN 1478-7210, 03/2018, Volume 16, Issue 3, pp. 205 - 218
β-lactam/β-lactamase inhibitor combinations | extended-spectrum β-lactamase-producing Enterobacteriaceae | treatment outcomes | β-lactamase | Antibiotic resistance | extended-spectrum β–lactamase-producing Enterobacteriaceae | Index Medicus
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7. Full Text New Delhi metallo-β-lactamase- type carbapenemases producing escherichia coli isolates from hospitalized patients: A pilot study
by Grover, Shyam Sunder and Doda, Ananya and Gupta, Nupur and Gandhoke, Inderjeet and Batra, Jyoti and Hans, Charoo and Khare, Shashi
Indian journal of medical research (New Delhi, India : 1994), ISSN 0971-5916, 07/2017, Volume 146, Issue July, pp. 105 - 110
Extended-spectrum beta-lactamases | Metallo-β-lactamase | New Delhi metallo-β-lactamase type 1 | New Delhi metallo-β-lactamase variants | Immunology | Life Sciences & Biomedicine | Medicine, General & Internal | General & Internal Medicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Urine | Intensive care | E coli | Antibiotics | Antimicrobial agents | Amino acids | Urinary tract infections | Hospitalization | Drug resistance | Index Medicus | Original | metallo-β-lactamase | Extended-spectrum beta-lactamases - metallo-β-lactamase - New Delhi metallo-β-lactamase type 1 - New Delhi metallo-β-lactamase variants
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8. Full Text Use of ferrous iron by metallo-β-lactamases
by Cahill, Samuel T and Tarhonskaya, Hanna and Rydzik, Anna M and Flashman, Emily and McDonough, Michael A and Schofield, Christopher J and Brem, Jürgen
Journal of inorganic biochemistry, ISSN 0162-0134, 10/2016, Volume 163, pp. 185 - 193
Metallo-β-lactamase | Carbapenem | β-Lactam antibiotics | Metalloenzyme | Antibiotic resistance | Zinc hydrolase | Biochemistry & Molecular Biology | Physical Sciences | Chemistry, Inorganic & Nuclear | Chemistry | Life Sciences & Biomedicine | Science & Technology | beta-Lactamases - chemistry | Metalloproteins - chemistry | Bacillus cereus - enzymology | Iron - chemistry | Bacterial Proteins - chemistry | Index Medicus | MBL, metallo-β-lactamase | ROO, rubredoxin:oxygen reductase | SBL, serine-β-lactamase | Pce, phosphorylcholine esterase | EDTA, ethylenediaminetetraacetic acid | ETHE1, ethylmalonic encephalopathy 1 | IC50, half maximal inhibitory concentration | CPSF, cleavage | TCEP·HCl, tris(2-carboxyethyl)phosphine hydrochloride salt | NDM-1, New Delhi metallo-β-lactamase 1 | PMSF, phenylmethylsulfonyl fluoride | IPTG, isopropyl β-D-1-thiogalactopyranoside | VIM-2, Verona integron-encoded metallo-β-lactamase 2 | SNM, sensitivity to nitrogen mustard | polyadenylation specificity factor | SDS-PAGE, sodium dodecyl sulfate polyacrylamide gel electrophoresis | ESI MS, electrospray ionisation mass spectrometry | BcII, metallo-β-lactamase II from Bacillus cereus
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9. Full Text Avibactam Sensitizes Carbapenem-Resistant NDM-1-Producing Klebsiella pneumoniae to Innate Immune Clearance
by Ulloa, Erlinda R and Dillon, Nicholas and Tsunemoto, Hannah and Pogliano, Joe and Sakoulas, George and Nizet, Victor
The Journal of infectious diseases, ISSN 0022-1899, 08/2019, Volume 220, Issue 3, pp. 484 - 493
Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Klebsiella Infections - drug therapy | Klebsiella pneumoniae - drug effects | Azabicyclo Compounds - immunology | Klebsiella pneumoniae - immunology | beta-Lactamases - immunology | Humans | Mice, Inbred C57BL | Carbapenem-Resistant Enterobacteriaceae - metabolism | Klebsiella Infections - microbiology | Anti-Bacterial Agents - therapeutic use | Immunity, Innate - immunology | Animals | Carbapenems - pharmacology | Klebsiella Infections - immunology | Azabicyclo Compounds - therapeutic use | Female | Carbapenem-Resistant Enterobacteriaceae - immunology | Mice | Klebsiella pneumoniae - metabolism | beta-Lactamases - metabolism | Drug Resistance, Multiple, Bacterial - immunology | Microbial Sensitivity Tests - methods | Penicillin-binding protein | β-Lactam antibiotics | Cell walls | Immune clearance | Innate immunity | Leukocytes (neutrophilic) | β-Lactamase | Drug resistance | Penicillin-binding protein 2 | Immunosuppressive agents | Metallo-β-lactamase | Antimicrobial peptides | Penicillin | Public health | Index Medicus | Abridged Index Medicus | Major and Brief Reports | non–β-lactam β-lactamase inhibitors | innate immunity | avibactam | New Delhi metallo-β-lactamase (NDM) | platelet | neutrophil | Klebsiella pneumoniae | human serum
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