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Expert Opinion on Drug Discovery, ISSN 1746-0441, 09/2013, Volume 8, Issue 9, pp. 1095 - 1116
Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) have been on the increase during the past decade, due to the steady growth of the elderly and... 
acyl t-RNA synthase inhibitor | Clp protease inhibitor | methicillin-resistant Staphylococcus aureus | two-component system inhibitor | elongation factor G inhibitor | linezolid | antibacterial agents | combination therapy | daptomycin | vancomycin | β-lactamase inhibitor | antibacterial vaccine | dihydropteroate synthase inhibitor | peptidoglycan biosynthesis inhibitor | Pol IIIC inhibitor | electron transport inhibitor | RNA-polymerase inhibitor | phage therapy | peptide deformylase inhibitor | menaquinone biosynthesis inhibitor | Gram-positive pathogens | antibiotics | antimicrobial peptides | dihydrofolate reductase inhibitor | FAS II inhibitor | Linezolid | Peptide deformylase inhibitor | Daptomycin | Dihydropteroate synthase inhibitor | Vancomycin | Combination therapy | Antimicrobial peptides | Menaquinone biosynthesis inhibitor | Antibacterial vaccine | Dihydrofolate reductase inhibitor | Acyl t-RNA synthase inhibitor | Elongation factor G inhibitor | Antibacterial agents | Electron transport inhibitor | Peptidoglycan biosynthesis inhibitor | Antibiotics | Methicillin-resistant Staphylococcus aureus | Phage therapy | Two-component system inhibitor | SOFT-TISSUE INFECTIONS | INTENSIVE-CARE UNITS | beta-lactamase inhibitor | RESISTANT STAPHYLOCOCCUS-AUREUS | PHARMACOLOGY & PHARMACY | IN-VITRO ACTIVITY | TOREZOLID PHOSPHATE TR-701 | BRIDGED BICYCLIC MACROLIDE | DIHYDROFOLATE-REDUCTASE INHIBITOR | QUALITY-CONTROL RANGES | Anti-Bacterial Agents - therapeutic use | Animals | Bacterial Infections - drug therapy | Drug Resistance, Multiple, Bacterial | Humans | Drug Discovery | Methicillin-Resistant Staphylococcus aureus | elongation factor G (EF-G) inhibitor | peptide deformylase (PDF) inhibitor | methicillin-resistant Staphylococcus aureus (MRSA) | PolIIC inhibitor | β5 -lactamase inhibitor
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 02/2014, Volume 24, Issue 3, pp. 780 - 785
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 01/2018, Volume 28, Issue 2, pp. 214 - 221
The emergence of antibiotic drug (like carbapenem) resistance is being a global crisis. Among those resistance factors of the β-lactam antibiotics, the... 
Metallo-β-lactamase | Cyclic dithiocarbamate | NDM-1 inhibitor | Antibiotic resistance | ANTIBIOTICS | CHEMISTRY, MEDICINAL | SMALL MOLECULES | CARBAPENEMS | CHEMISTRY, ORGANIC | ERADICATE BIOFILMS | DETECTABLE RESISTANCE | IN-VIVO | CARBONIC-ANHYDRASES | BACTERIAL-RESISTANCE | SPECTRUM | Metallo-beta-lactamase | ENTEROBACTERIACEAE | Index Medicus
Journal Article
Journal of Applied Microbiology, ISSN 1364-5072, 03/2018, Volume 124, Issue 3, pp. 667 - 681
Aims-lactamase inhibitor resistance (BLIR) among the uropathogenic Escherichia coli (UPEC) minimizes treatment options. This study aimed to identify... 
molecular docking | lactamase | TEM | cephalosporin resistance | Escherichia coli | uropathogenic | uropathogenic Escherichia coli | TEM β-lactamase | INFECTIONS | ENZYME | COMMUNITY | ANTIBACTERIAL ACTIVITY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | MICROBIOLOGY | TEM beta-lactamase | FLAVONOIDS
Journal Article
Clinical Microbiology and Infection, ISSN 1198-743X, 2019, Volume 25, Issue 4
Objectives: Checkerboard experiments followed by fractional inhibitory concentration (FIC) index determinations are commonly used to assess in vitro... 
Checkerboard | β-lactamase inhibitor | β-Lactam antibiotic | Combinations | Pharmacodynamic interactions | CEFTAZIDIME | INFECTIOUS DISEASES | INFECTIONS | beta-lactamase inhibitor | MICROBIOLOGY | COMBINATION | beta-Lactam antibiotic | IN-VITRO ACTIVITY | ENTEROBACTERIACEAE
Journal Article
BBA - Proteins and Proteomics, ISSN 1570-9639, 08/2013, Volume 1834, Issue 8, pp. 1648 - 1659
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 09/2010, Volume 132, Issue 38, pp. 13320 - 13331
Journal Article
Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 8/2009, Volume 64, Issue 2, pp. 326 - 329
Background NXL104 is a novel-structure β-lactamase inhibitor with potent activity against both class A and class C enzymes. Among the class A carbapenemases,... 
KPC inhibition | β-Lactamase | Carbapenem resistance | INFECTIOUS DISEASES | RESISTANT KLEBSIELLA-PNEUMONIAE | MICROBIOLOGY | IDENTIFICATION | EMERGENCE | ISOLATE | FRANCE | carbapenem resistance | DISSEMINATION | PHARMACOLOGY & PHARMACY | beta-lactamase | STRAIN | Original Research | β-lactamase
Journal Article
Journal of Enzyme Inhibition and Medicinal Chemistry, ISSN 1475-6366, 01/2019, Volume 34, Issue 1, pp. 1414 - 1425
Journal Article