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Biochemical and Biophysical Research Communications, ISSN 0006-291X, 07/2014, Volume 450, Issue 1, pp. 906 - 911
Journal Article
Journal Article
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 60, pp. 101012 - 101025
We investigated the effects of neuron-restrictive silencer factor (NRSF) on proliferation of endogenous nerve stem cells (NSCs) and on μ- and δ-opioid receptor... 
Cerebral ischemia | μ- and δ-opioid receptors | Proliferation | Apoptosis | Neuron-restrictive silencer factor
Journal Article
Cellular Signalling, ISSN 0898-6568, 2009, Volume 21, Issue 7, pp. 1218 - 1228
studies have shown that the Regulator of G protein Signaling 4 (RGS4) interacts with the C-termini of μ- and δ-opioid receptors (μ-OR, δ-OR) (Georgoussi et... 
μ, δ-opioid receptors | Protein–protein interactions | Internalization | Extracellular signal-regulated kinases | G proteins | Regulators of G protein signaling | Signaling complex | Protein-protein interactions
Journal Article
Molecular Pain, ISSN 1744-8069, 4/2018, Volume 14, p. 1744806918769492
Opioid receptors play an important role in mediating the spinal analgesia. The μ-opioid receptor is the major target of opioid drugs widely used in clinics.... 
µ-opioid receptor | clinical opioids | receptor internalization | morphine
Journal Article
Cellular Signalling, ISSN 0898-6568, 2006, Volume 18, Issue 6, pp. 771 - 782
To define receptor subdomains important for protein interaction and identify components of novel signal transduction complexes for the μ- and δ-opioid... 
RGS proteins | μ-, δ-opioid receptors | Gα, Gβγ subunits | Signaling complex | GST fusion peptides
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 08/2009, Volume 616, Issue 1-3, pp. 115 - 121
Orally active dual μ-/δ-opioid receptor antagonist, H-Dmt-Tic-Lys-NH-CH -Ph (MZ-2) was applied to study body weight gain, fat content, bone mineral density,... 
Obesity | Dual μ-/δ-opioid receptor antagonist | Dmt-Tic pharmacophore | Bone mineral density | Glucose | Insulin | ob/ob mouse | bone mineral density | glucose | insulin | dual μ | obesity | δ-opioid receptor antagonist | ob mice
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 09/1998, Volume 18, Issue 18, pp. 7285 - 7295
Previous pharmacological studies have indicated the possible existence of functional interactions between μ-, δ- and κ-opioid receptors in the CNS. We have... 
G- protein coupling | μ-Opioid receptor knock-out | μ-δ-κ-opioid receptor interactions | Respiration | δ-κ analgesia | Vas deferens | Receptors | Opiacis | μ-opioid receptor knock-out | Drogoaddicció | Aspectes moleculars | G-protein coupling
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2009, Volume 616, Issue 1, pp. 115 - 121
Orally active dual μ-/δ-opioid receptor antagonist, H-Dmt-Tic-Lys-NH-CH -Ph (MZ-2) was applied to study body weight gain, fat content, bone mineral density,... 
Obesity | Dual μ-/δ-opioid receptor antagonist | Dmt-Tic pharmacophore | Bone mineral density | Glucose | Insulin | ob/ob mouse
Journal Article
Neuroscience, ISSN 0306-4522, 2004, Volume 127, Issue 2, pp. 497 - 503
Conventional brain microdialysis was used to assess basal and cocaine-induced dopamine (DA) levels in the nucleus accumbens of wildtype (WT) C57BL/6J mice and... 
knockout mice | cocaine | conventional microdialysis | μ- and Δ-opioid receptors | DOR | area under the curve | EDTA | artificial cerebrospinal fluid | ethylenediaminetetra-acetate | AUC | analysis of variance | ANOVA | Δ opioid receptors | aCSF | dopamine
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2000, Volume 387, Issue 2, pp. 163 - 169
Inflammatory hyperalgesia was induced in wild-type, heterozygous and μ- opioid receptor knockout mice after an intraplantar injection of complete Freund's... 
μ-Opioid receptor | Knockout mice | Inflammation
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2000, Volume 388, Issue 3, pp. 241 - 248
We examined the effects of [D-Pen ,D-Pen ]enkephalin (DPDPE), [D- Ala ,Glu ]deltorphin (DELT), and (+)-4-[(αR)-α((2S,5R)-4-Allyl-2,5-... 
μ-Opioid receptor | Antinociception | μ-Opioid receptor-knockout mice | Opioid drug | δ-Opioid receptor | G protein
Journal Article