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帕金森病 (6518) 6518
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中西医结合疗法 (34) 34
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中华医学杂志:英文版, ISSN 0366-6999, 2017, Volume 130, Issue 15, pp. 1856 - 1866
Objective:The aim of this study was to summarize recent studies on nondopaminergic options for the treatment of motor symptoms in Parkinson's disease (PD).Data... 
辅助治疗 | 运动障碍 | 症状 | 5-羟色胺 | 帕金森病 | 多巴胺能药物 | 临床试验 | PubMed
Journal Article
中华医学杂志:英文版, ISSN 0366-6999, 2015, Issue 13, pp. 1761 - 1764
The studies of the natural progression of Parkinson's disease (PD) in Chinese populations have been lacking. To address this issue and obtain a preliminary... 
帕金森氏病 | 时间跨度 | NA | PD | 帕金森病 | 队列 | 药物 | 自然
Journal Article
中华医学杂志:英文版, ISSN 0366-6999, 2016, Issue 9, pp. 1053 - 1058
Background: Proteasome subunits (PSMB) and transporter associated with antigen processing (TAP) loci are located in the human leukocyte antigen (HLA) Class I1... 
人类白细胞抗原 | 基因型频率 | 亚单位 | 相关分析 | 帕金森病 | 蛋白酶体 | 神经退行性疾病 | AP2基因
Journal Article
神经科学通报:英文版, ISSN 1673-7067, 2016, Volume 32, Issue 6, pp. 572 - 576
Abstract Olfactory dysfunction has been reported in Parkinson's disease (PD) patients carrying the LRRK2 G2019S variant in Caucasians but rarely in those with... 
运动障碍 | 对照组 | 基因分型 | 帕金森病 | IPD | 嗅觉功能 | 患者 | 变种
Journal Article
中华医学杂志:英文版, ISSN 0366-6999, 2015, Volume 128, Issue 21, pp. 2906 - 2912
Background: Urination disorders are common in Parkinson's disease (PD) and respond poorly to medication. This study aimed to analyze the risk factors for... 
帕金森氏病 | Logistic回归分析 | 药物反应 | 帕金森病 | 左旋多巴 | 严重程度 | 排尿障碍 | 患者 | Nocturia; Parkinson′s Disease; Risk Factors; Urine Disorders
Journal Article
中国结合医学杂志:英文版, ISSN 1672-0415, 2016, Issue 10, pp. 723 - 727
Parkinson's disease (PD) is a well-known neurodegenerative disease caused by dopaminergic cell death in the nigrostriatal pathway. Recent studies have shown... 
治疗 | 医学理论 | PD | 穴位 | 帕金森病 | 动物 | 神经退行性疾病 | 细胞死亡
Journal Article
中国神经再生研究:英文版, ISSN 1673-5374, 2016, Volume 11, Issue 8, pp. 1339 - 1346
Rasagiline,a monoamine oxidase-B inhibitor,and bis(propyl)-cognitin(B3C),a novel dimer are reported to be neuroprotective.Herein,the synergistical... 
帕金森病 | 高效液相色谱法 | 多巴胺能神经元 | 协同作用 | 神经保护作用
Journal Article
中华医学杂志:英文版, ISSN 0366-6999, 2015, Issue 13, pp. 1809 - 1814
Background: The vitamin D receptor (VDR) gene has been identified as a candidate gene liar susceptibility to Parkinson's disease (PD), but results from genetic... 
维生素D受体 | 遗传模型 | 万方数据库 | 可信区间 | 基因多态性 | 受体基因 | 帕金森病 | PubMed
Journal Article
中国神经再生研究:英文版, ISSN 1673-5374, 2016, Volume 11, Issue 5, pp. 729 - 730
Deep brain stimulation(DBS)is a well established electrophysiological treatment initially applied to treat medication-refractory motor symptoms in Parkinson's... 
胆碱能 | 输入 | 帕金森病 | 电刺激 | 小脑 | 深部 | 精神疾病 | 桥核 | Spinal cord | Gait | Deep brain stimulation | Posture
Journal Article
中国神经再生研究:英文版, ISSN 1673-5374, 2016, Volume 11, Issue 2, pp. 205 - 207
One of the greatest unmet needs in the treatment of Parkinson’s disease(PD)is a disease-modifying therapy,which can halt the ongoing degeneration of... 
疗法 | 治疗 | 候选人 | 帕金森病 | NTFS | 神经营养因子 | 疾病 | 多巴胺能神经元 | Proteins | Immunoglobulins | Brain research | Clinical trials | Gene therapy | Patients | Vectors (Biology) | Failure
Journal Article
中华医学杂志:英文版, ISSN 0366-6999, 2015, Volume 128, Issue 5, pp. 593 - 601
Background:Neuroimaging studies have found that functional changes exist in patients with Parkinson's disease (PD).However,the majority of functional magnetic... 
fMRI | 低频振荡 | 功能性磁共振成像 | 帕金森病 | 幅度 | 神经活动 | 功能磁共振成像 | 静息态 | Functional Magnetic Resonance Imaging; Longitudinal; Parkinson′s Disease; Resting State
Journal Article
中国神经再生研究:英文版, ISSN 1673-5374, 2016, Volume 11, Issue 12, pp. 1969 - 1975
Striatal neurons can be either projection neurons or interneurons, with each type exhibiting distinct susceptibility to various types of brain damage. In this... 
大鼠 | 质调节 | 钙结合蛋白 | 帕金森病 | 免疫组织化学 | 投射神经元 | 环磷酸腺苷 | 纹状体
Journal Article
中国神经再生研究:英文版, ISSN 1673-5374, 2016, Volume 11, Issue 11, pp. 1735 - 1738
Parkinson's disease (PD) is a common, progressive neurodegenerative disease characterised by degeneration of nigrostriatal dopaminergic neurons, aggregation of... 
治疗 | 组蛋白乙酰转移酶 | 帕金森病 | 表观遗传 | 基因组 | 组蛋白乙酰化 | 多巴胺能神经元 | 神经保护作用
Journal Article
神经科学通报:英文版, ISSN 1673-7067, 2014, Issue 3, pp. 409 - 416
The 1-methyl-4-phenyl-1,2,3,4-tetrahydropyridine (MPTP)-induced parkinsonism model, particularly in non-human primates, remains the gold-standard for studying... 
转运体 | 食蟹猴 | 帕金森病 | MPTP | 多巴胺能神经元 | PET | 纹状体 | 单胺
Journal Article
中国神经再生研究:英文版, ISSN 1673-5374, 2016, Volume 11, Issue 4, pp. 566 - 567
Journal Article
中国神经再生研究:英文版, ISSN 1673-5374, 2015, Volume 10, Issue 12, pp. 1934 - 1935
Roles of Keap1-Nrf2 pathway in brain:Neuronal survival and neurogenesis are impaired in neurodegenerative diseases such as Parkinson's disease and Alzheimer's... 
神经元 | 突起生长 | 帕金森病 | 存活 | 阿尔茨海默病 | 生长因子 | 神经退行性疾病 | 神经发生 | PATHWAYS | OXIDATIVE STRESS | ROLES | DISEASE | ACID PHENETHYL ESTER | NEUROGENESIS | NEURODEGENERATION | TOXICITY | PC12 CELLS | NEUROSCIENCES | MOLECULES | CELL BIOLOGY | Regeneration | Nervous system | Research | Neurophysiology | Antioxidants | Proteins | Acids | Disease | Natural products | Neurogenesis
Journal Article
中国神经再生研究:英文版, ISSN 1673-5374, 2016, Volume 11, Issue 4, pp. 570 - 571
The progressive loss of dopaminergic neurons in the ventral mesencephalon is the main pathological hallmark of Parkinson’s disease(PD).Drugs currently... 
病理特征 | 副作用 | 帕金森病 | 因子 | 进行性 | 神经退行性疾病 | 多巴胺能神经元 | 旁分泌 | Proteins | Oxidative stress | Cytokines | Tissue engineering | MicroRNAs | Stem cells | Lipids
Journal Article
中国神经再生研究:英文版, ISSN 1673-5374, 2016, Volume 11, Issue 1, pp. 86 - 87
Advancing age and increased lifespan of human populations worldwide in the mid-nineteenth century,have led to a significant increase in the incidence of... 
科学研究 | 白藜芦醇 | 氧化应激 | 左旋多巴 | 帕金森病 | 神经退行性疾病 | 健康问题 | 抗氧化剂 | NEUROSCIENCES | CELL BIOLOGY | Antioxidants | Care and treatment | Resveratrol | Nervous system | Degeneration | Research | Risk factors | Proteins | Oxidative stress | Phosphorylation | Free radicals | Disease | Neurodegeneration | Amyotrophic lateral sclerosis | Kinases
Journal Article
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