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index medicus (195) 195
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PLoS ONE, ISSN 1932-6203, 06/2014, Volume 9, Issue 6, p. e100954
textabstractDysfunction of renin-angiotensin system (RAS) contributes to the pathogenesis of diabetic retinopathy (DR). Prorenin, the precursor of renin is... 
PLASMA PRORENIN | IN-VITRO | NONPROTEOLYTIC ACTIVATION | BINDING-KINETICS | HUMAN (PRO)RENIN RECEPTOR | MULTIDISCIPLINARY SCIENCES | SMOOTH-MUSCLE-CELLS | ANGIOTENSIN-II | HANDLE-REGION PEPTIDE | (MREN-2)27 RAT | MULLER CELLS | Blood Pressure | Diabetic Retinopathy - drug therapy | Apoptosis - genetics | Fumarates - administration & dosage | Diabetic Retinopathy - pathology | Receptors, Cell Surface - antagonists & inhibitors | Retinal Ganglion Cells - metabolism | Gliosis - pathology | Renin - genetics | Inflammation Mediators - metabolism | Disease Models, Animal | Amides - pharmacology | Cytokines - metabolism | Gliosis - metabolism | Rats | Receptors, Cell Surface - metabolism | Mice, Transgenic | Diabetic Retinopathy - metabolism | Diabetic Retinopathy - genetics | Animals | Renin - antagonists & inhibitors | Fumarates - pharmacology | Oligopeptides - administration & dosage | Oligopeptides - pharmacology | Amides - administration & dosage | Diabetic retinopathy | Genetic engineering | Cytokines | Angiotensin | Drugs | Retinopathy | Peptides | Pathogenesis | Streptozocin | Transgenic | Retina | Smooth muscle | Kinases | Renin | Rodents | Inhibition | Capillaries | Angiotensin II | Hypertension | Internal medicine | Diabetes mellitus | Pharmacology | Inflammation | siRNA | Tumor necrosis factor-α | Medicine | Gliosis | Cell death | Photoreceptors | Diabetes | Metabolic disorders | Apoptosis
Journal Article
Experimental Lung Research, ISSN 0190-2148, 5/2015, Volume 41, Issue 4, pp. 199 - 207
ABSTRACTPurpose/Aim: We performed a randomized, prospective animal study to investigate whether inhibiting the renin-angiotensin system with a (pro)renin... 
(pro)renin receptor blocker | prorenin | acute lung injury | renin-angiotensin system | Acute lung injury | Reninangiotensin system | Prorenin | MEDIATOR | NONPROTEOLYTICALLY ACTIVATED PRORENIN | SEPSIS | RESPIRATORY-DISTRESS-SYNDROME | PROTECTS | INHIBITION | THERAPY | RESPIRATORY SYSTEM | INFLAMMATION | DECOY PEPTIDE | Endotoxins | Pneumonia - pathology | Pneumonia - prevention & control | Bronchoalveolar Lavage Fluid - immunology | Male | Receptors, Cell Surface - antagonists & inhibitors | Proton-Translocating ATPases - metabolism | Acute Lung Injury - prevention & control | Pneumonia - chemically induced | Inflammation Mediators - metabolism | Pneumonia - immunology | Pulmonary Edema - prevention & control | Acute Lung Injury - metabolism | Lung - metabolism | Proton-Translocating ATPases - antagonists & inhibitors | Pulmonary Edema - metabolism | Neutrophil Infiltration - drug effects | Cytoprotection | Disease Models, Animal | Lung - pathology | Cytokines - metabolism | Anti-Inflammatory Agents - pharmacology | Receptors, Cell Surface - metabolism | Acute Lung Injury - pathology | Rats, Sprague-Dawley | Peptides - pharmacology | Pulmonary Edema - chemically induced | Animals | Acute Lung Injury - chemically induced | Lung - drug effects | Acute Lung Injury - immunology | Pneumonia - metabolism | Lung - immunology
Journal Article
Circulation: Heart Failure, ISSN 1941-3289, 09/2012, Volume 5, Issue 5, pp. 645 - 652
Journal Article
Journal Article
American Journal of Physiology - Renal Physiology, ISSN 0363-6127, 2014, Volume 306, Issue 10, pp. F1179 - F1189
Journal Article
Clinical and Experimental Pharmacology and Physiology, ISSN 0305-1870, 05/2010, Volume 37, Issue 5, pp. 569 - 573
Journal Article
Clinical Science, ISSN 0143-5221, 08/2012, Volume 123, Issue 3, pp. 121 - 133
Tissue angiotensin generation depends on the uptake of circulating (kidney-derived) renin and/or its precursor prorenin [together denoted as (pro)renin]. Since... 
(Pro)renin receptor | Vacuolar H | Renin | Mannose 6-phosphate/insulin-like growth factor II receptor | Prorenin | Renin-binding protein |