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Gynecologic Oncology, ISSN 0090-8258, 2013, Volume 132, Issue 2, pp. 474 - 482
Abstract Objective Over-expression of the aldo-keto reductase family 1 member C3 (AKR1C3) has been demonstrated in many human cancers. Lipocalin 2 (LCN2) is... 
Hematology, Oncology and Palliative Medicine | Obstetrics and Gynecology | Lipocalin 2 | Cancer of the uterine cervix | Metastasis | Aldo-keto reductase family 1 member C3 | Matrix metalloproteinase-2 | RADICAL HYSTERECTOMY | PROGNOSTIC-FACTORS | GELATINASE-ASSOCIATED LIPOCALIN | HUMAN-PAPILLOMAVIRUS | OVARIAN-CANCER | DIHYDRODIOL DEHYDROGENASE | OBSTETRICS & GYNECOLOGY | BREAST-CANCER | LUNG-CANCER | ONCOLOGY | PROSTATE-CANCER | SQUAMOUS-CELL CARCINOMA | Lipocalins - biosynthesis | Hydroxyprostaglandin Dehydrogenases - deficiency | Prognosis | Humans | Uterine Cervical Neoplasms - pathology | Acute-Phase Proteins - genetics | Proto-Oncogene Proteins - biosynthesis | Hydroxyprostaglandin Dehydrogenases - metabolism | Cell Movement - physiology | Neoplasm Recurrence, Local - pathology | RNA, Messenger - biosynthesis | Transfection | Uterine Cervical Neoplasms - metabolism | Lipocalins - genetics | HEK293 Cells | 3-Hydroxysteroid Dehydrogenases - metabolism | Female | Matrix Metalloproteinase 2 - biosynthesis | 3-Hydroxysteroid Dehydrogenases - deficiency | Cytoskeleton - pathology | Neoplasm Recurrence, Local - metabolism | RNA, Messenger - genetics | Cytoskeleton - genetics | Gene Silencing | Proto-Oncogene Proteins - genetics | Uterine Cervical Neoplasms - genetics | Disease Progression | Hydroxyprostaglandin Dehydrogenases - genetics | Matrix Metalloproteinase 2 - genetics | Aldo-Keto Reductase Family 1 Member C3 | Lipocalin-2 | Cell Line, Tumor | Cytoskeleton - metabolism | Neoplasm Recurrence, Local - genetics | HeLa Cells | 3-Hydroxysteroid Dehydrogenases - genetics | Acute-Phase Proteins - biosynthesis | Development and progression | Cervical cancer | Cancer
Journal Article
Journal Article
International Journal of Clinical and Experimental Pathology, ISSN 1936-2625, 2012, Volume 5, Issue 4, pp. 278 - 289
Human aldo-keto reductase family 1 member C3 (AKR1C3) was initially identified as a critical enzyme in reducing 5 alpha-dihydrotestosterone (5 alpha-DHT) to 5... 
Adenocarcinoma | Stomach | Squamous cell carcinoma | Gastroesophageal junction | Lung | AKR1C3 | Non-small cell carcinoma | Small cell carcinoma | Esophagus | ANDROGEN RECEPTOR | gastroesophageal junction | POLYCYCLIC AROMATIC-HYDROCARBONS | HUMAN OVARIAN | adenocarcinoma | stomach | PATHOLOGY | DIHYDRODIOL DEHYDROGENASE | lung | ESTROGEN-RECEPTOR-BETA | LUNG-CANCER | non-small cell carcinoma | ONCOLOGY | 5 17-BETA-HYDROXYSTEROID-DEHYDROGENASE AKR1C3 | TISSUE DISTRIBUTION | PROSTATE-CANCER | small cell carcinoma | REVEALS ROLES | esophagus | squamous cell carcinoma | Immunohistochemistry | Predictive Value of Tests | Adenocarcinoma - pathology | Adenocarcinoma of Lung | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Oklahoma | 3-Hydroxysteroid Dehydrogenases - analysis | Small Cell Lung Carcinoma - enzymology | Lung Neoplasms - pathology | Male | Stomach Neoplasms - pathology | Esophageal Neoplasms - pathology | Aged, 80 and over | Adult | Female | Stomach Neoplasms - enzymology | Carcinoma, Squamous Cell - enzymology | Diagnosis, Differential | Lung Neoplasms - enzymology | Biomarkers, Tumor - analysis | Adenocarcinoma - enzymology | Esophagogastric Junction - pathology | Esophageal Neoplasms - enzymology | Esophagogastric Junction - enzymology | Small Cell Lung Carcinoma - pathology | Aldo-Keto Reductase Family 1 Member C3 | Hydroxyprostaglandin Dehydrogenases - analysis | Aged
Journal Article
Journal Article
Journal Article
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 12/2012, Volume 72, Issue 23, pp. 6142 - 6152
Androgen receptor (AR) signaling persists in castration-resistant prostate carcinomas (CRPC), because of several mechanisms that include increased AR... 
STEROIDOGENESIS | SELECTIVE INHIBITOR | DIHYDROTESTOSTERONE LEVELS | ONCOLOGY | ABIRATERONE ACETATE | RECEPTOR | INCREASED SURVIVAL | CYP17 INHIBITOR | CASTRATION | I CLINICAL-TRIAL | HORMONAL-THERAPY | 3-Hydroxysteroid Dehydrogenases - biosynthesis | Immunohistochemistry | Neoplasms, Hormone-Dependent - metabolism | Prostatic Neoplasms - metabolism | Humans | Receptors, Androgen - metabolism | Gene Expression Regulation, Neoplastic | Transcriptome | Androgens - biosynthesis | Data Mining | Male | Hydroxyprostaglandin Dehydrogenases - metabolism | Neoplasms, Hormone-Dependent - genetics | RNA, Messenger - biosynthesis | Neoplasm Metastasis | Prostatic Neoplasms - genetics | Cytochrome P-450 CYP3A - genetics | Receptors, Androgen - biosynthesis | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - metabolism | 3-Hydroxysteroid Dehydrogenases - metabolism | Neoplasms, Hormone-Dependent - enzymology | Cytochrome P-450 CYP3A - biosynthesis | Prostatic Neoplasms - pathology | RNA, Messenger - genetics | Hydroxyprostaglandin Dehydrogenases - biosynthesis | Hydroxyprostaglandin Dehydrogenases - genetics | Orchiectomy | Gene Expression Regulation, Enzymologic | Receptors, Androgen - genetics | Aldo-Keto Reductase Family 1 Member C3 | Cytochrome P-450 CYP3A - metabolism | Neoplasms, Hormone-Dependent - pathology | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - genetics | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - biosynthesis | Cell Line, Tumor | Prostatic Neoplasms - enzymology | 3-Hydroxysteroid Dehydrogenases - genetics | Androgens - metabolism | abiraterone | androgen synthesis | testosterone | dihydrotestosterone | AKR1C3 | CYP17 | MDV3100 (enzalutamide) | Prostate cancer
Journal Article
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 10/2017, Volume 276, pp. 194 - 202
Journal Article