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Journal of Neurochemistry, ISSN 0022-3042, 09/2012, Volume 122, Issue 5, pp. 941 - 951
J. Neurochem. (2012) 122, 941951. Abstract In vitro and in vivo models of Parkinsons disease (PD) suggest that increased oxidant production leads to... 
hydroethidine | mitochondria | glycolysis | reactive oxygen species | NADPH OXIDASE | OXYGEN SPECIES PRODUCTION | OXIDATIVE STRESS | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOPAMINERGIC-NEURONS | PARAQUAT | NEUROSCIENCES | BRAIN MITOCHONDRIA | REACTIVE OXYGEN | ANIMAL-MODELS | CELL-CULTURE | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine - pharmacology | Insecticides - pharmacology | Rats | Herbicides - pharmacology | Adrenergic Agents - pharmacology | Dose-Response Relationship, Drug | Neurotoxins - pharmacology | Animals | Oligomycins - pharmacology | Oxidopamine - pharmacology | Time Factors | Dopamine Agents - pharmacology | Oxygen Consumption - drug effects | Adenosine Triphosphate - metabolism | Dopaminergic Neurons - metabolism | Proton Ionophores - pharmacology | Rotenone - pharmacology | Superoxides - metabolism | Dopaminergic Neurons - drug effects | Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone - pharmacology | Paraquat - pharmacology | Cell Line, Transformed | Energy Metabolism - drug effects | Glucose metabolism | Herbicides | Parkinson's disease | Cell death | Analysis | Superoxide | Mitochondrial DNA | Universities and colleges | Cells | Neurochemistry | Mitochondria | Neurotransmitters | Bioenergetics | Parkinsons disease | Apoptosis | Index Medicus | Dopamine | Neurodegenerative diseases | 6-Hydroxydopamine | Acidification | Data processing | Oxygen consumption | Rotenone | Toxicants | MPP super(+) | Oxidants | Glycolysis | Paraquat | Oxidation | Movement disorders
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 08/2012, Volume 122, Issue 3, pp. 582 - 593
Parkinson’s disease‐like symptoms inducing compound affects hippocampus. Cognitive deficits observed in PD paradigms might be related to the hippocampus. Acute... 
CA1 | MPTP | synaptic plasticity | hippocampus | dopamine | Parkinson’s disease | Parkinson's disease | RAT | BIOCHEMISTRY & MOLECULAR BIOLOGY | LTP | METABOTROPIC GLUTAMATE RECEPTORS | CA1 NEURONS | NEUROSCIENCES | IN-VITRO | SLICES | PROTEASOME | MICE | LONG-TERM POTENTIATION | PARKINSONS-DISEASE | Sulpiride - pharmacology | Electric Stimulation | Neural Pathways - drug effects | Neuronal Plasticity - drug effects | Male | Excitatory Postsynaptic Potentials - drug effects | Quinoxalines - pharmacology | Long-Term Potentiation - drug effects | Time Factors | Tetrodotoxin - pharmacology | Neurons - drug effects | Receptors, Dopamine - physiology | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine - pharmacology | Mice, Inbred C57BL | Valine - analogs & derivatives | Sodium Channel Blockers - pharmacology | Excitatory Amino Acid Agonists - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Benzazepines - pharmacology | Biophysics | Hippocampus - cytology | Neurotoxins - pharmacology | Patch-Clamp Techniques | Animals | Dopamine Antagonists - pharmacology | alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - pharmacology | Mice | Valine - pharmacology | In Vitro Techniques | Neurochemistry | Neurology | Dopamine | Index Medicus | Neurodegenerative diseases | Glutamic acid receptors (ionotropic) | Brain slice preparation | Long-term potentiation | Cognitive ability | Plasticity (presynaptic) | N-Methyl-D-aspartic acid receptors | Antagonists | Glutamic acid receptors | Vesicles | Dopamine D1 receptors | Plasticity (synaptic) | Synaptic transmission | Dopamine D2 receptors | Hippocampus | Movement disorders | Dopamine receptors
Journal Article
Glia, ISSN 0894-1491, 01/2014, Volume 62, Issue 1, pp. 145 - 157
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2015, Volume 10, Issue 12, pp. e0144848 - e0144848
Neuronal death in Parkinson's disease (PD) is often preceded by axodendritic tree retraction and loss of neuronal functionality. The presence of non-functional... 
Dopaminergic Neurons - pathology | Mesencephalon - metabolism | Male | Neuroprotective Agents - pharmacology | Dopaminergic Neurons - metabolism | Lipid Peroxidation - drug effects | Dopaminergic Neurons - drug effects | MPTP Poisoning - pathology | Mesencephalon - drug effects | Female | Hydroxyquinolines - pharmacology | Neurites - drug effects | Mesencephalon - pathology | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine - pharmacology | 2,2'-Dipyridyl - pharmacology | Nerve Fibers - pathology | Deferoxamine - pharmacology | Nerve Fibers - metabolism | Mice, Inbred C57BL | Rats | Nerve Fibers - drug effects | Neurites - metabolism | Antioxidants - pharmacology | MPTP Poisoning - drug therapy | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine - antagonists & inhibitors | Rats, Sprague-Dawley | Synaptophysin - agonists | Neurites - pathology | Tyrosine 3-Monooxygenase - biosynthesis | Animals | G Protein-Coupled Inwardly-Rectifying Potassium Channels - agonists | Iron Chelating Agents - pharmacology | MPTP Poisoning - metabolism | Synaptophysin - biosynthesis | Mice | Primary Cell Culture | G Protein-Coupled Inwardly-Rectifying Potassium Channels - biosynthesis | Pyridones - pharmacology | Antioxidants | Care and treatment | Usage | Parkinson's disease | Neurons | Chelating agents | Dopaminergic mechanisms | Health aspects | 8-Hydroxyquinoline | Cell culture | Oxidative stress | Basal ganglia | Model testing | Laboratories | Medical services | Parkinsons disease | Homeostasis | Acetylcysteine | Life assessment | Nervous system | Iron | Biology | MPP | Tyrosine 3-monooxygenase | Fibers | Neurodegeneration | Rodents | Aging | Damage accumulation | Movement disorders | Dopamine receptors | Trees | Tyrosine | Synaptophysin | Dopamine | Potassium channels (inwardly-rectifying) | Neurodegenerative diseases | Axonogenesis | Medical treatment | Hydroxylase | Oral administration | Central nervous system diseases | Hydroxyquinoline | Hypotheses | Brain research | Hypoxia | MPTP | Apoptosis | Index Medicus
Journal Article
Phytomedicine, ISSN 0944-7113, 02/2017, Volume 25, pp. 93 - 99
is a traditional Chinese herb normally which is used to treat the osteoporosis, cardiovascular dysfunction, and to improve neurological and sexual function in... 
Icariin | Dopamine | Parkinson's disease | Phosphatidylinositol 3-kinase | Mitogen-activated protein kinase kinase | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | CELLS | APOPTOSIS | CHEMISTRY, MEDICINAL | ALZHEIMERS-DISEASE | IGF-I RECEPTOR | HERBA-EPIMEDII | DOPAMINERGIC-NEURONS | PLANT SCIENCES | INTEGRATIVE & COMPLEMENTARY MEDICINE | DEPENDENT OSTEOBLASTIC FUNCTIONS | PHARMACOLOGY & PHARMACY | MICE | DIFFERENTIATION | EXPRESSION | Neuroprotective Agents - therapeutic use | Tyrosine 3-Monooxygenase - metabolism | Epimedium - chemistry | Drugs, Chinese Herbal - pharmacology | Parkinson Disease - drug therapy | Corpus Striatum - metabolism | Neuroprotective Agents - pharmacology | Dopaminergic Neurons - metabolism | Dopaminergic Neurons - drug effects | Female | Flavonoids - pharmacology | Parkinson Disease - metabolism | Phosphorylation - drug effects | Phytotherapy | Chromones - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Drugs, Chinese Herbal - therapeutic use | Phosphatidylinositol 3-Kinase - metabolism | Dopamine - metabolism | Disease Models, Animal | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | Animals | MAP Kinase Signaling System - drug effects | Signal Transduction - drug effects | Corpus Striatum - drug effects | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Parkinson Disease - etiology | Index Medicus
Journal Article
Journal of Pineal Research, ISSN 0742-3098, 11/2009, Volume 47, Issue 4, pp. 293 - 300
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 08/2003, Volume 306, Issue 2, pp. 752 - 762
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 01/2010, Volume 30, Issue 3, pp. 1166 - 1175
We report that rapamycin, an allosteric inhibitor of certain but not all actions of the key cellular kinase mammalian target of rapamycin ( mTOR), protects... 
MAMMALIAN TARGET | ACTIVATION | CELLULAR-MODELS | GENE-EXPRESSION | NIGRAL NEURONS | AKT | AUTOPHAGY | IMMUNOPHILIN LIGANDS | NEUROSCIENCES | MTOR | NERVE GROWTH-FACTOR | Neuroprotective Agents - therapeutic use | Tyrosine 3-Monooxygenase - metabolism | Humans | Male | Green Fluorescent Proteins - genetics | Intracellular Signaling Peptides and Proteins - metabolism | PC12 Cells | Dose-Response Relationship, Drug | Transfection - methods | Time Factors | Transcription Factors - pharmacology | Cell Death - drug effects | Neurons - drug effects | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Disease Models, Animal | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine - pharmacology | Sirolimus - therapeutic use | Drug Administration Schedule | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Protein-Serine-Threonine Kinases - genetics | Nerve Growth Factor - pharmacology | Rats | Transcription Factors - antagonists & inhibitors | Parkinsonian Disorders - chemically induced | Transcription Factors - genetics | Serine - metabolism | Cycloheximide - pharmacology | Gene Expression Regulation - drug effects | Parkinson Disease | Transcription Factors - metabolism | Oxidopamine - toxicity | Animals | Analysis of Variance | Parkinsonian Disorders - pathology | Mice | Parkinsonian Disorders - prevention & control | TOR Serine-Threonine Kinases | Index Medicus | Parkinson's disease | 6-Hydroxydopamine | neurodegeneration | mTOR | RTP801 | MPTP | rapamycin
Journal Article