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chemistry, organic (53) 53
1-n-iminosugars (41) 41
glycosidase inhibitors (33) 33
enzyme inhibitors - chemical synthesis (22) 22
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Tetrahedron, ISSN 0040-4020, 02/2018, Volume 74, Issue 8, pp. 852 - 858
The fluorinated piperidine iminosugars and their -octyl and -decyl derivatives were synthesized from -mannose/ -xylose using nucleophilic fluorination as the... 
Glycosidase inhibitory activity | Iminosugars | Immunosuppressive activity | Conformational analysis | 1-N-IMINOSUGARS | 1-DEOXYNOJIRIMYCIN | ANALOGS | CHEMISTRY, ORGANIC | POTENT | GLUCOSIDASE | AZASUGARS | CHEMISTRY | IMMUNOMODULATING AGENTS
Journal Article
Organic Letters, ISSN 1523-7060, 01/2012, Volume 14, Issue 2, pp. 596 - 599
A de novo synthesis of novel polyhydroxylated N-alkoxypiperidines based on the ring-closing double reductive amination of 1,5-dialdehydes, obtained by... 
DESIGN | 1-N-IMINOSUGARS | NUCLEOSIDES | 1-AZASUGARS | CHEMISTRY, ORGANIC | IMINOSUGARS | GLYCOSIDASE INHIBITORS | POTENTIAL INHIBITORS | SUGARS | DERIVATIVES | D-GLUCOSE | Organic chemistry | Chemical Sciences
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 01/2018, Volume 59, Issue 3, pp. 231 - 233
A short and efficient method for synthesizing -cytoxazone the corresponding oxazoline intermediate was developed. The formation of the oxazoline ring, which... 
Intramolecular cyclization | Oxazolidinone | epi-Cytoxazone | Trichloroacetimidate | Benzylic substitution | Oxazoline | AMINO-ALCOHOLS | ENANTIOSELECTIVE SYNTHESIS | 1-N-IMINOSUGARS | CHEMISTRY, ORGANIC | ENT-STAUROSPORINE | STREPTOMYCES SP | L-IDURONIC ACID | CYTOKINE MODULATOR | (-)-CYTOXAZONE | BETA-HYDROXY ACIDS | CONJUGATE ADDITION
Journal Article
RSC Advances, ISSN 2046-2069, 05/2013, Volume 3, Issue 17, pp. 5794 - 5797
A simple and highly facile protocol has been developed for the stereoselective synthesis of 1-deoxy-norcastanospermine from readily available D-glucose.... 
1-N-IMINOSUGARS | ANALOGS | CHEMISTRY | LYSOSOMAL STORAGE | ISOFAGOMINE | GLYCOSIDASE INHIBITORS | SUGARS | CHEMISTRY, MULTIDISCIPLINARY | D-GLUCOSE
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 10/2015, Volume 56, Issue 41, pp. 5607 - 5609
A facile and environmentally friendly synthesis of both enantiomers of a biologically important 1- -iminosugar (azasugar) is presented. To this end, the use of... 
Azasugar | 2,3-Epoxyamides | Sodium chlorite | Tandem oxidation | Stereoselective oxidation | OXIDATION | 1-N-IMINOSUGARS | STRATEGY | CHEMISTRY, ORGANIC | ISOFAGOMINE | EPOXIDATION | AMINES | MANGANESE(III) ACETYLACETONATE | CHLORINATION | CARBOXYLIC-ACIDS | AMIDES | Physiological aspects | Lipids | Usage | Enantiomers | Sustainable development
Journal Article
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 04/2012, Volume 10, Issue 14, pp. 2760 - 2773
Synthesis of isofagomine has been achieved by implementation of aza-Claisen rearrangement of 2-C-hydroxymethyl glycals as a key step. The above rearrangement... 
ROUTE | SUGARS APPLICATION | POTENT | 1-N-IMINOSUGARS | ANALOGS | GLYCOSYL | GLYCOSIDASE INHIBITORY-ACTIVITY | CHEMISTRY, ORGANIC | STEREOSELECTIVE-SYNTHESIS | BETA-GLUCOSIDASE | 5-EPI-ISOFAGOMINE | Carbohydrates - chemistry | Hydroxylation | Aza Compounds - chemistry | Imino Pyranoses - chemical synthesis | Molecular Structure | Methylation | Ether - chemistry
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 08/2013, Volume 78, Issue 15, pp. 7380 - 7397
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 09/2011, Volume 2, Issue 9, pp. 682 - 686
The new emerging immunosuppressive effects displayed by iminosugars have not been much investigated so far. Several new N-alkyl dideoxy iminoalditols were... 
synthesis | immunosuppressive agent | Iminosugar | mouse skin allograft | DESIGN | CHEMISTRY, MEDICINAL | 1,5-DIDEOXY-1,5-IMINOXYLITOL | 1-N-IMINOSUGARS | MECHANISM | ANALOGS | TRANSPLANTATION | CYCLOSPORINE-A | DISEASE | INHIBITORS | DERIVATIVES
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 11/2014, Volume 22, Issue 21, pp. 5776 - 5782
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2008, Volume 49, Issue 48, pp. 6812 - 6815
The versatility of 3,4- -isopropylidene-2- -methyl- -arabinonolactone [from -erythronolactone] as a chiron for complex piperidines and pyrrolidines is... 
CALCIUM HYDROXIDE | 1-N-IMINOSUGARS | ANALOGS | KILIANI | ISOMERIZATION | CHEMISTRY, ORGANIC | AMADORI KETOSES | CARBOHYDRATE BUILDING-BLOCKS | ENANTIOMER | Temperature inversions | Heterocyclic aromatic compounds
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2008, Volume 49, Issue 2, pp. 339 - 342
A simple and novel method is presented for the synthesis of aminocyclopentenecarboxylic ester diastereomers with an N-heteroatom in the ring. A simple strategy... 
Enzymatic resolution | Cyclic β-amino acids | Dihydroxylation | Piperidine | Ring closure | DESIGN | 1-N-IMINOSUGARS | ring closure | CHEMISTRY, ORGANIC | piperidine | cyclic beta-amino acids | OLIGOMERS | L-IDURONIC ACID | PEPTIDES | CHEMISTRY | dihydroxylation | INHIBITORS | DERIVATIVES | PROBE | enzymatic resolution
Journal Article
Tetrahedron: Asymmetry, ISSN 0957-4166, 12/2010, Volume 21, Issue 24, pp. 2966 - 2972
The synthesis of (3 ,4 ,5 )-3-(2-hydroxyethyl)piperidine-3,4,5-triol has been described from -glucose. The base promoted cyclization for the construction of... 
SELECTIVE DEPROTECTION | 1-DEOXYNOJIRIMYCIN | 1-N-IMINOSUGARS | CHEMISTRY, ORGANIC | CHEMISTRY, PHYSICAL | SUGARS | TERMINAL ISOPROPYLIDENE ACETALS | CHEMISTRY, INORGANIC & NUCLEAR | TRITYL ETHERS | POTENT | AZASUGARS | 1-AZASUGARS | GLUCOSE
Journal Article
Journal Article
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