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1-o-acylceramide synthase (25) 25
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JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 12/2008, Volume 181, Issue 11, pp. 7873 - 7881
Macrophages have long been known to secrete a Phospholipase A(2) with an acidic pH optimum in response to phagocytic stimuli. However, the enzyme or enzymes... 
ENZYME | METABOLISM | CLONING | SUPERFAMILY | 1-O-ACYLCERAMIDE SYNTHASE | IMMUNOLOGY | PROTEINS | IDENTIFICATION
Journal Article
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 01/2012, Volume 53, Issue 1, pp. 152 - 156
PURPOSE. The present study was conducted to determine lysosomal phospholipase A2 (LPLA2) activity in the aqueous humor (AH) and to identify the possible... 
ENZYME-ACTIVITIES | PHAGOCYTOSIS | TRABECULAR-MESHWORK CELLS | CLONING | DISEASE | ANTERIOR SEGMENT | OPHTHALMOLOGY | ALVEOLAR MACROPHAGES | 1-O-ACYLCERAMIDE SYNTHASE | TISSUES | Animals | Aqueous Humor - cytology | Swine | Lysosomes - enzymology | Aqueous Humor - enzymology | Phospholipases A2 - metabolism | Chromatography, Thin Layer | Blotting, Western | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2013, Volume 110, Issue 13, pp. 5097 - 5102
Journal Article
Molecular Cancer Research, ISSN 1541-7786, 03/2018, Volume 16, Issue 3, pp. 470 - 475
Journal Article
Journal Article
GLYCOCONJUGATE JOURNAL, ISSN 0282-0080, 2003, Volume 20, Issue 1, pp. 25 - 32
A series of inhibitors of glucosylceramide synthesis, the PDMP based family of compounds, has been developed as a tool for the study of sphingolipid... 
APOPTOSIS | phospholipase A | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROLIFERATION | CELL-GROWTH | SPHINGOLIPID METABOLISM | ceramide | PDMP | 1-O-acylceramide | CLONING | ENZYMES | 1-O-ACYLCERAMIDE SYNTHASE | lysosome | EXPRESSION
Journal Article
JOURNAL OF LIPID RESEARCH, ISSN 0022-2275, 11/2005, Volume 46, Issue 11, pp. 2441 - 2447
Lysosomal phospholipase A(2) (LPLA(2)) is an acidic phospholipase that is highly expressed in alveolar macrophages and that may play a role in the catabolism... 
DOMAIN | LECITHIN-CHOLESTEROL ACYLTRANSFERASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | lipase | macrophage | LCAT | FAMILY | phosphatidylethanolamine | ENZYME | phosphatidylcholine | INTERFACIAL RECOGNITION | 1-O-ACYLCERAMIDE SYNTHASE | phospholipid | PROTEINS | surfactant
Journal Article
JOURNAL OF LIPID RESEARCH, ISSN 0022-2275, 10/2006, Volume 47, Issue 10, pp. 2268 - 2279
Lysosomal phospholipase A(2) (Lpla2) is highly expressed in alveolar macrophages and may mediate the phospholipid metabolism of surfactant. Studies on the... 
2-ARACHIDONOYLGLYCEROL | alveolar macrophage | LECITHIN-CHOLESTEROL ACYLTRANSFERASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR | IDENTIFICATION | transacylation | phosphatidylethanolamine | CLONING | phosphatidylcholine | GENERATION | 1-O-ACYLCERAMIDE SYNTHASE | EXPRESSION | surfactant
Journal Article
JOURNAL OF LIPID RESEARCH, ISSN 0022-2275, 10/2007, Volume 48, Issue 10, pp. 2255 - 2263
A novel lysosomal phospholipase A(2) (LPLA2) with specificity toward phosphatidylethanolamine and phosphatidylcholine was previously purified and cloned. LPLA2... 
CELLS | 1-O-hexadecyl-2-acetyl-sn-glycerol | PROTEIN-KINASE-C | BIOCHEMISTRY & MOLECULAR BIOLOGY | N-acetylsphingosine | LYSOPHOSPHOLIPASE | D-threo-1-phenyl-2decanoylamino-3-morpholino-propanol | ceramide | amiodarone | RABBIT PLATELETS | CLONING | TRANSACYLASE ACTIVITIES | PURIFICATION | PLATELET-ACTIVATING-FACTOR | 1-O-ACYLCERAMIDE SYNTHASE | anandamide
Journal Article
Journal Article
LEUKEMIA, ISSN 0887-6924, 05/2002, Volume 16, Issue 5, pp. 902 - 910
The retinoid, N-(4-hydroxyphenyl)retinamide (4-HPR), mediates p53-independent cytotoxicity and can increase reactive oxygen species and ceramide In solid tumor... 
GROWTH-INHIBITION | 4-HPR | CARCINOMA CELLS | GLUCOSYLCERAMIDE SYNTHASE | INDUCED APOPTOSIS | PPMP | glucosylceramide | TRANS-RETINOIC ACID | NEUROBLASTOMA-CELLS | FENRETINIDE 4-HPR | BREAST-CANCER | ceramide | ONCOLOGY | acute lymphoblastic leukemia | 1-O-acylceramide | SERINE PALMITOYLTRANSFERASE | GENE-EXPRESSION | HEMATOLOGY
Journal Article
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