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10058-f4 (28) 28
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adenosine triphosphate - deficiency (2) 2
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International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 03/2019, Volume 108, pp. 7 - 16
Based on the frequent over-expression of c-Myc in hematologic malignancies and its crucial role in the regulation of diverse oncogenic pathways involved in... 
Acute leukemia | PTEN | PI3K pathway | c-Myc inhibition | 10058-F4 | p53 | TRANSCRIPTION FACTORS | CHEMOSENSITIVITY | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | AKT | CELL BIOLOGY | ONCOGENE | METABOLISM | SIGNALING PATHWAY | RESISTANCE | NF-KAPPA-B | EXPRESSION | Arsenic | Oncology, Experimental | Research | Blood banks | Tumor proteins | Cancer | Apoptosis
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2014, Volume 9, Issue 8, p. e105381
Journal Article
Journal Article
AMERICAN JOURNAL OF CANCER RESEARCH, ISSN 2156-6976, 2017, Volume 7, Issue 8, pp. 1724 - U133
Clinical management of malignant mesothelioma (MM) is very challenging due to marked resistance of this tumor to chemotherapy. Various mechanisms lead to a... 
PROTEIN | cytostasis | Mesothelioma | apoptosis | PROLIFERATION | EPIGENETICS | ONCOLOGY | 10058-F4 | GENETICS | MYC | GROWTH | PAK | NF2 | MUTATIONS | INHIBITOR
Journal Article
Genes & cancer, ISSN 1947-6019, 06/2010, Volume 1, Issue 6, pp. 650 - 659
Protein-protein interactions between members of the Myc transcription factor network are potential targets of small molecule inhibitors and stabilizers.... 
Mad | ID proteins | Max | 10058-F4 | Monographs
Journal Article
Oncotarget, ISSN 1949-2553, 2015, Volume 6, Issue 18, pp. 15857 - 15870
Journal Article
Journal of Functional Foods, ISSN 1756-4646, 12/2015, Volume 19, pp. 236 - 247
The dietary flavonoids luteolin and quercetin are reported to inhibit cancer mobility; however, the regulatory effect of luteolin and quercetin on RPS12 is... 
C-Myc | Luteolin | Invasiveness | Cervical cancer | Quercetin | RPS12 | LY294002 | 10058-F4 | DMSO | Rapamycin | MTT | Agarose | TYROSINE KINASE | FOOD SCIENCE & TECHNOLOGY | PROLIFERATION | HYBRIDIZATION | CDNA | IDENTIFICATION | RIBOSOME BIOGENESIS | NUTRITION & DIETETICS | GENE | SIMVASTATIN | CELL | EXPRESSION
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 12/2010, Volume 335, Issue 3, pp. 715 - 727
Journal Article
by Lee, YS and Heo, W and Son, CH and Kang, CD and Park, YS and Bae, J
MOLECULAR MEDICINE REPORTS, ISSN 1791-2997, 10/2019, Volume 20, Issue 4, pp. 3301 - 3307
c-Myc is a characteristic oncogene with dual functions in cell proliferation and apoptosis. Since the overexpression of the c-Myc proto-oncogene is a common... 
MEDICINE, RESEARCH & EXPERIMENTAL | APOPTOSIS | ACTIVATION | K562 | c-Myc | SUSCEPTIBILITY | natural killer group 2 member D ligands | RECEPTOR | TUMOR-CELLS | INDUCTION | INHIBITION | ONCOLOGY | 10058-F4 | EXPRESSION | T-CELLS
Journal Article
Oncotarget, ISSN 1949-2553, 2015, Volume 6, Issue 32, pp. 32380 - 32395
Many oncogenic signals originate from abnormal protein-protein interactions that are potential targets for small molecule inhibitors. However, the therapeutic... 
10074-G5 | Neuroblastoma | Myeloma | 10058-F4 | Quinone methide | BET inhibitors | quinone methide | TRANSCRIPTION FACTORS | MULTIPLE-MYELOMA | DNA-BINDING | neuroblastoma | REGULATED GENE-PRODUCTS | ACUTE MYELOID-LEUKEMIA | CELL BIOLOGY | myeloma | SMALL-MOLECULE INHIBITORS | PROMYELOCYTIC LEUKEMIA-CELLS | SUPPRESSES INVASION | PROTEIN-PROTEIN INTERACTIONS | NF-KAPPA-B | Neoplasms - metabolism | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - antagonists & inhibitors | Triterpenes - pharmacology | Apoptosis - drug effects | Humans | Protein Multimerization | Structure-Activity Relationship | Molecular Targeted Therapy | Dose-Response Relationship, Drug | Transfection | Neoplasms - genetics | Time Factors | Drug Design | Protein Structure, Quaternary | Antineoplastic Agents, Phytogenic - metabolism | Tumor Cells, Cultured | Triterpenes - metabolism | Proto-Oncogene Proteins c-myc - metabolism | Neoplasms - drug therapy | Signal Transduction - drug effects | Cell Cycle Checkpoints - drug effects | Proto-Oncogene Proteins c-myc - antagonists & inhibitors | Cell Line, Tumor | Protein Binding | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Cell Proliferation - drug effects | Proto-Oncogene Proteins c-myc - genetics | Antineoplastic Agents, Phytogenic - pharmacology | Neoplasms - pathology
Journal Article
Journal of Translational Medicine, ISSN 1479-5876, 08/2014, Volume 12, Issue 1, pp. 226 - 226
Journal Article
Cancer Medicine, ISSN 2045-7634, 04/2017, Volume 6, Issue 4, pp. 788 - 797
Journal Article