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Journal Article
CELL CYCLE, ISSN 1538-4101, 01/2011, Volume 10, Issue 2, pp. 278 - 284
The mammary gland is a dynamic organ that only undergoes complete differentiation during pregnancy. Differentiation is fuelled by asymmetric division of stem... 
MATRIX | differentiation | proliferation | TISSUE | MAMMARY STEM-CELLS | 14-3-3 sigma (sigma) | p63 | CULTURE | ADULT | CELL BIOLOGY | senescence | MORPHOGENESIS | stem cell | MALIGNANT BREAST | lactation | mammary gland | transient amplifying | HIERARCHY | CYCLE
Journal Article
VETERINARY PATHOLOGY, ISSN 0300-9858, 03/2018, Volume 55, Issue 2, pp. 233 - 240
14-3-3 sigma is a protein expressed in many epithelial tissues associated with essential cell functions, including cell-cycle control, apoptosis, and... 
stratifin | NEOPLASMS | SIGMA PROTEIN | 14-3-3 sigma | EARLY-STAGE | vimentin | cytokeratin | PATHOLOGY | CANCER | TUMORS | oncology | kidney | renal cell carcinoma | dogs | LUNG ADENOCARCINOMA | human mammary epithelial marker 1 | VETERINARY SCIENCES | urinary | immunohistochemistry | TISSUES | PROGRESSION
Journal Article
by Lu, YC and Wang, P and Wu, QG and Zhang, RK and Kong, A and Li, YF and Lee, SC
PROTEOMICS, ISSN 1615-9853, 04/2019, Volume 19, Issue 7
It has been reported recently that type 2 diabetes promotes centrosome amplification via 14-3-3 sigma/ROCK1 complex. In the present study, 14-3-3 sigma... 
MORTALITY | insulin | APG-2 | BIOCHEMISTRY & MOLECULAR BIOLOGY | 14-3-3 sigma | INVOLVEMENT | BIOCHEMICAL RESEARCH METHODS | INDUCTION | palmitic acid | Hsp74 | HEAT-SHOCK-PROTEIN | centrosome amplification | CANCER-PATIENTS | high glucose | STRUCTURAL BASIS | OVER-EXPRESSION | TUMORIGENESIS
Journal Article
ONCOLOGY LETTERS, ISSN 1792-1074, 11/2017, Volume 14, Issue 5, pp. 5257 - 5264
Loss of 14-3-3 sigma expression through DNA methylation has been associated with carcinogenesis and the prognosis for various cancer types. Detection of... 
non-small cell lung cancer | CIRCULATING DNA | HYPERMETHYLATION | ADENOCARCINOMA | 14-3-3 sigma | survival | SERUM | prognosis | INACTIVATION | ONCOLOGY | methylation | SIGMA | STRATIFIN | immunohistochemistry | PROTEINS | CARCINOMA | PROGRESSION
Journal Article
BIOMOLECULAR NMR ASSIGNMENTS, ISSN 1874-2718, 04/2019, Volume 13, Issue 1, pp. 103 - 107
14-3-3 proteins are a group of seven dimeric adapter proteins that exert their biological function by interacting with hundreds of phosphorylated proteins,... 
14-3-3 proteins | NMR resonance assignments | BIOPHYSICS | SPECTROSCOPY | Drug discovery | PROTEINS | Protein-protein interactions | Quantitative Biology - Biomolecules
Journal Article
ONCOGENE, ISSN 0950-9232, 08/2014, Volume 33, Issue 35, pp. 4407 - 4417
Wig-1, also known as ZMAT3, is a p53 target gene that encodes an RNA-binding zinc-finger protein involved in the regulation of mRNA stability through binding... 
AU-rich element-binding proteins | Wig-1 | HUR | STABILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | 14-3-3 sigma | DNA-DAMAGE | P53-ACTIVATED GENE | p53 | CELL BIOLOGY | ONCOLOGY | AU-RICH ELEMENTS | AU-rich element | GENETICS & HEREDITY | ZINC-FINGER PROTEIN | FAS | CCR4-NOT COMPLEX | MESSENGER-RNA DECAY | STRESS | EXPRESSION
Journal Article
ONCOGENE, ISSN 0950-9232, 12/2011, Volume 30, Issue 48, pp. 4791 - 4801
14-3-3 sigma, a gene upregulated by p53 in response to DNA damage, exists as part of a positive-feedback loop, which activates p53 and is a human cancer... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | 14-3-3 sigma | CSN6 | DNA-DAMAGE | CANCER | BREAST | NEGATIVE REGULATOR | P53 | CELL BIOLOGY | COP1 | LIGHT CONTROL | ONCOLOGY | ubiquitination | GENETICS & HEREDITY | ARABIDOPSIS | PROTEINS | REGULATES C-JUN | TUMOR-GROWTH | Transformation | Cell survival | DNA damage | proteasomes | AKT protein | Data processing | Tumorigenicity | signalosomes | p53 protein | 14-3-3 protein | Ubiquitin-protein ligase | Cancer
Journal Article
by Qin, X and Qiu, F and Zou, Z
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ISSN 0006-291X, 11/2017, Volume 493, Issue 1, pp. 568 - 572
Lung cancer, in particular, non-small cell lung cancer (NSCLC), is the leading cause of cancer-related mortality. Cis-Diamminedichloroplatinum (cisplatin,... 
FINGER PROTEIN | NSCLC | BIOCHEMISTRY & MOLECULAR BIOLOGY | Chemoresistance | 14-3-3 sigma | CANCER | Cisplatin | EFP | BIOPHYSICS | ROLES | MDM2 | TRIM25 | TUMOR-GROWTH | PROGRESSION | MOLECULAR-MECHANISMS
Journal Article
by Li, F and Huang, Y and Huang, YY and Kuang, YS and Wei, YJ and Xiang, L and Zhang, XJ and Jia, ZC and Jiang, S and Li, JY and Wan, Y
MOLECULAR IMMUNOLOGY, ISSN 0161-5890, 12/2017, Volume 92, pp. 180 - 189
B cells play a critical role in immune responses both in physiological and pathological conditions, and microRNAs have been shown to play important roles in... 
RECOMBINATION | MiR-146a | IgE | BIOCHEMISTRY & MOLECULAR BIOLOGY | 14-3-3 sigma | SENSITIVITY | Class switch | PROLIFERATION | INDUCTION | IMMUNOLOGY | Asthma | RESPONSES | INFLAMMATION | MOUSE MODEL | PROTEINS
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 10/2013, Volume 110, Issue 41, pp. E3937 - E3944
The protein 14-3-3s (stratifin) is frequently described as a tumor suppressor silenced in about 80% of breast tumors. Intriguingly, we show that 14-3-3s... 
GENE-EXPRESSION SIGNATURE | cytoskeleton | MULTIDISCIPLINARY SCIENCES | basal breast cancer | triple-negative | SACCHAROMYCES-CEREVISIAE | CANCER | EPITHELIAL-CELLS | 14-3-3 family | motility | PROTEINS | STRESS | IN-SITU | PROGRESSION | XENOGRAFT MODEL
Journal Article
by Wang, C and Zhu, XY and Feng, WW and Yu, YH and Jeong, KJ and Guo, W and Lu, YL and Mills, GB
AMERICAN JOURNAL OF CANCER RESEARCH, ISSN 2156-6976, 2016, Volume 6, Issue 1, pp. 27 - 37
Yes-associated protein (YAP), the central mediator of Hippo pathway, not only regulates a diversity of cellular processes during development but also plays a... 
YES-ASSOCIATED PROTEIN | SURVIVAL | APOPTOSIS | B COLORIMETRIC ASSAY | ACTIVATION | COMPLEX | PHOTODYNAMIC THERAPY | 14-3-3 sigma | YAP | CHRONIC MYELOID-LEUKEMIA | CELL-DEATH | ONCOLOGY | PATHWAY | endometrial cancer | Verteporfin
Journal Article
In Vitro Cellular & Developmental Biology - Animal, ISSN 1071-2690, 10/2018, Volume 54, Issue 9, pp. 658 - 665
Journal Article
Journal Article
APMIS, ISSN 0903-4641, 04/2018, Volume 126, Issue 4, pp. 309 - 313
The objective of this study was to analyze the expression and clinical role of 14‐3‐3 family proteins in high‐grade serous carcinoma (HGSC). Protein expression... 
high‐grade serous carcinoma | effusion | chemotherapy | 14‐3‐3 proteins | survival | 14-3-3 proteins | high-grade serous carcinoma | METHYLATION | MICROBIOLOGY | IMMUNOLOGY | PATHOLOGY | EPITHELIAL OVARIAN-CANCER | POOR SURVIVAL | EFFUSIONS | DISEASE | PROGNOSTIC MARKER | Proteins | Chemotherapy | Carcinoma | Metastasis | Analysis | Cancer | Immunohistochemistry | Parameters | Cell survival | Mitosis | Survival | Metastases | Tubulin | Protein expression | Peritoneum
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 05/2000, Volume 97, Issue 11, pp. 6049 - 6054
Expression of 14-3-3 sigma (sigma) is induced in response to DNA damage, and causes cells to arrest in G(2), By SAGE (serial analysis of gene expression)... 
CELLS | CPG ISLAND | MULTIDISCIPLINARY SCIENCES | TELOMERASE ACTIVITY | TRANSCRIPTIONAL REPRESSION | CHROMOSOME 1P | METHYLATION STATUS | RECEPTOR GENE | EXPRESSION | PROGRESSION | DUCTAL CARCINOMA | G2 Phase - genetics | Protein Biosynthesis | Epithelial Cells - metabolism | Humans | Neoplasm Proteins - physiology | Recombinant Fusion Proteins - physiology | Cell Line, Transformed - drug effects | DNA Repair - genetics | Tyrosine 3-Monooxygenase | RNA, Messenger - biosynthesis | Cell Line - drug effects | Transfection | Cell Transformation, Neoplastic - genetics | Cell Cycle Proteins - genetics | Female | Transcription, Genetic | Gene Expression Regulation, Neoplastic - drug effects | Neoplasm Proteins - genetics | Proteins - physiology | Breast - cytology | Neoplasm Proteins - biosynthesis | RNA, Messenger - genetics | Gene Silencing | Radiation Tolerance - genetics | Azacitidine - analogs & derivatives | Tumor Cells, Cultured - metabolism | Cell Cycle Proteins - biosynthesis | Proteins - genetics | Azacitidine - pharmacology | Breast Neoplasms - genetics | RNA, Neoplasm - biosynthesis | Breast Neoplasms - pathology | CpG Islands | RNA, Neoplasm - genetics | 14-3-3 Proteins | Cell Cycle Proteins - physiology | DNA Methylation - drug effects | 14-3-3s gene | 14-3-3 protein | 14-3-3 ^s gene | hypermethylation | 5-aza-2'-deoxycytidine
Journal Article
JOURNAL OF CELL SCIENCE, ISSN 0021-9533, 07/2013, Volume 126, Issue 14, pp. 3031 - 3031
Plakoglobin (c-catenin), a constituent of the adherens junction and desmosomes, has signaling capabilities typically associated with tumor/metastasis... 
SCC9 | SUBCELLULAR-DISTRIBUTION | 14-3-3 sigma | E-CADHERIN | Gene expression | BETA-CATENIN | Tumor suppressor | TUMOR-SUPPRESSOR P53 | p53 | CELL BIOLOGY | GAMMA-CATENIN EXPRESSION | PROSTATE-CANCER CELLS | MUTANT P53 | GENE-EXPRESSION | Plakoglobin | SQUAMOUS CARCINOMA-CELLS | WILLEBRAND-FACTOR PROMOTER
Journal Article
by Lu, YC and Wang, P and Wang, J and Ma, R and Lee, SC
JOURNAL OF CELLULAR PHYSIOLOGY, ISSN 0021-9541, 07/2019, Volume 234, Issue 7, pp. 11511 - 11523
We have recently reported that type 2 diabetes promotes centrosome amplification via enhancing the expression, biding, and centrosome translocation of... 
PHYSIOLOGY | PCNA | INSTABILITY | ROCK1 | PHOSPHORYLATION | 14-3-3 sigma | KINASE | JNK1 | NPM | CELL BIOLOGY | centrosome amplification | SIGNAL-TRANSDUCTION | NUCLEOPHOSMIN | INVASION | Stat3 | DUPLICATION | diabetes | EXPRESSION | TUMORIGENESIS
Journal Article
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