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triazoles - pharmacology (41) 41
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molecular docking (36) 36
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azole antifungals (33) 33
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Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2013, Volume 288, Issue 44, pp. 31602 - 31615
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 09/2013, Volume 57, Issue 9, pp. 4151 - 4163
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 04/2017, Volume 61, Issue 4
Journal Article
Journal Article
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 01/2017, Volume 18, Issue 1, p. 177
Twenty-three thiazolin-4-ones were synthesized starting from phenylthioamide or thiourea derivatives by condensation with alpha-monochloroacetic acid or ethyl... 
Thiazolin-4-one | Antifungal activity | ADME-Tox predictors | Lanosterol 14α-demethylase | Lipophilicity | Molecular docking | lanosterol 14 alpha-demethylase | BIOCHEMISTRY & MOLECULAR BIOLOGY | DRUG DISCOVERY | LIBRARY | MODEL | antifungal activity | CHEMISTRY, MULTIDISCIPLINARY | molecular docking | lipophilicity | AGENTS | thiazolin-4-one | DERIVATIVES | Fungal Proteins - chemistry | 14-alpha Demethylase Inhibitors - chemistry | Models, Chemical | Antifungal Agents - chemical synthesis | Antifungal Agents - chemistry | Fungal Proteins - antagonists & inhibitors | 14-alpha Demethylase Inhibitors - chemical synthesis | Microbial Sensitivity Tests | Candida - classification | Spectrophotometry, Infrared | Mass Spectrometry | Drug Design | Protein Domains | Molecular Structure | Antifungal Agents - pharmacology | Candida - growth & development | Magnetic Resonance Spectroscopy | 14-alpha Demethylase Inhibitors - pharmacology | Thiazoles - chemical synthesis | Protein Binding | Thiazoles - chemistry | Molecular Docking Simulation | Sterol 14-Demethylase - metabolism | Thiazoles - pharmacology | Candida - drug effects | Sterol 14-Demethylase - chemistry | Fungal Proteins - metabolism | Nuclear magnetic resonance--NMR | Fungicides | Toxicity | Fungi | Synthesis | Thiourea | Chloroacetic acid | Carbon 13 | Cytochromes P450 | Lanosterol | Excretion | Fluconazole | Cytochrome P450 | Antifungal agents | Mass spectroscopy | Infrared spectra | Lead compounds | Derivatives | Organic chemistry | Screening | Thiourea derivatives | Mass spectrometry | Index Medicus | lanosterol 14α-demethylase
Journal Article
Scientific Reports, ISSN 2045-2322, 04/2014, Volume 4, Issue 1, pp. 1 - 11
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2016, Volume 11, Issue 12, p. e0167485
Azole antifungals, known as demethylase inhibitors (DMIs), target sterol 14 alpha-demethylase (CYP51) in the ergosterol biosynthetic pathway of fungal... 
MYCOSPHAERELLA-GRAMINICOLA | CYTOCHROME-P450 | ASPERGILLUS-FUMIGATUS | FUNGICIDES | MULTIDISCIPLINARY SCIENCES | AZOLE RESISTANCE | SENSITIVITY | TRIAZOLE RESISTANCE | MECHANISMS | MUTATIONS | CYP51 | Antifungal Agents - pharmacology | Catalytic Domain | 14-alpha Demethylase Inhibitors - chemistry | Molecular Conformation | Substrate Specificity | Saccharomyces cerevisiae - drug effects | Antifungal Agents - chemistry | Structure-Activity Relationship | Yeasts - drug effects | Yeasts - enzymology | Azoles - pharmacology | Agrochemicals - pharmacology | Azoles - chemistry | Microbial Sensitivity Tests | 14-alpha Demethylase Inhibitors - pharmacology | Protein Binding | Saccharomyces cerevisiae - enzymology | Molecular Structure | Sterol 14-Demethylase - metabolism | Sterol 14-Demethylase - chemistry | Binding Sites | Agrochemicals - chemistry | Cytochrome | Yeast | Fungicides | Hydrophobicity | Enantiomers | Proteins | Fungi | Antifungal activity | Agrochemicals | Sterols | Crop yield | Crystal structure | Recombinant | Prochloraz | Pathogens | Agricultural chemicals | Ergosterol | Lanosterol | Enzymes | Plants (botany) | Difenoconazole | Crop science | Tebuconazole | Crops | Pesticides | Crop protection | Dentistry | Disease control | Mutants | Membrane proteins | Fluquinconazole | Food security | Crop diseases | Mutation | Binding sites | Structure-function relationships
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 08/2016, Volume 57, Issue 8, pp. 1552 - 1563
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 12/2014, Volume 58, Issue 12, pp. 7121 - 7127
Journal Article