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Journal of Immunology, ISSN 0022-1767, 05/2017, Volume 198, Issue 9, pp. 3426 - 3435
Journal Article
Journal Article
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 01/2013, Volume 54, pp. 1 - 16
... expression of several inflammatory genes. Our data demonstrate that although the receptor-associated tyrosine kinases Jak2 and Tyk2 are activated after the recruitment... 
Monocytes | Free radicals | Cytokines | Gene regulation | ROS | Inflammation | Alternative activation | COLLAGEN-INDUCED ARTHRITIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | INTERLEUKIN-13 | RECEPTOR | 15-LIPOXYGENASE | MONOCYTE-ENRICHED FRACTIONS | CULTURED ENDOTHELIAL-CELLS | MONOAMINE-OXIDASE-A | ENDOCRINOLOGY & METABOLISM | CENTRIFUGAL ELUTRIATION CCE | PERIPHERAL-BLOOD MONOCYTES | LDL OXIDATION | Dual Specificity Phosphatase 1 - genetics | Reactive Oxygen Species - metabolism | Macrophage Activation - immunology | Humans | Receptors, Interleukin-4 - metabolism | Cells, Cultured | Gene Expression Regulation | STAT Transcription Factors - metabolism | TYK2 Kinase - metabolism | Interleukin-13 - immunology | Monocytes - immunology | Arachidonate 15-Lipoxygenase - metabolism | Receptors, Interleukin-13 - metabolism | Interleukin-4 - immunology | Janus Kinase 1 - metabolism | Signal Transduction - immunology | Janus Kinase 2 - metabolism | Tissue Inhibitor of Metalloproteinase-3 - metabolism | Dual Specificity Phosphatase 1 - metabolism | Macrophages - immunology | Monoamine Oxidase - metabolism | Tissue Inhibitor of Metalloproteinase-3 - genetics | Tyrosine | Anopheles | Monoamine oxidase | Phosphatases | Interleukins | Genes | Genetic research | Macrophages | Gene expression | Free radicals (Chemistry) | cytokines | alternative activation
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 36, pp. 14040 - 14064
Journal Article
Cellular Signalling, ISSN 0898-6568, 11/2017, Volume 39, pp. 44 - 54
Journal Article
Diabetes, ISSN 0012-1797, 02/2011, Volume 60, Issue 2, pp. 614 - 624
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 04/2012, Volume 53, Issue 4, pp. 686 - 695
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 2014, Volume 76, pp. 147 - 162
... (AA), induces CD36 expression through xanthine oxidase and NADPH oxidase-dependent ROS production and Syk and Pyk2-dependent STAT1 activation... 
CD36 | Foam cell | Syk | STAT1 | ROS | ATHEROSCLEROTIC LESIONS | OXIDATION | 15-LIPOXYGENASE MESSENGER-RNA | INDUCED ANGIOGENESIS | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | LOW-DENSITY-LIPOPROTEIN | CHRONIC DISEASE | SCAVENGER RECEPTOR CD36 | ENDOCRINOLOGY & METABOLISM | TYROSINE KINASE INHIBITOR | E-DEFICIENT MICE | CD36 Antigens - genetics | Immunoprecipitation | Reactive Oxygen Species - metabolism | Protein-Tyrosine Kinases - metabolism | NADPH Oxidases - metabolism | Arachidonate 12-Lipoxygenase - chemistry | Arachidonate 15-Lipoxygenase - chemistry | Male | Intracellular Signaling Peptides and Proteins - metabolism | Foam Cells - cytology | Macrophages, Peritoneal - cytology | Promoter Regions, Genetic - genetics | Foam Cells - drug effects | Focal Adhesion Kinase 2 - genetics | Protein-Tyrosine Kinases - genetics | STAT1 Transcription Factor - metabolism | CD36 Antigens - metabolism | Chromatin Immunoprecipitation | Focal Adhesion Kinase 2 - metabolism | Hydroxyeicosatetraenoic Acids - pharmacology | Coronary Artery Disease - pathology | Electrophoretic Mobility Shift Assay | Phosphorylation - drug effects | Intracellular Signaling Peptides and Proteins - genetics | Macrophages, Peritoneal - drug effects | Real-Time Polymerase Chain Reaction | Syk Kinase | Foam Cells - metabolism | Coronary Artery Disease - metabolism | RNA, Messenger - genetics | Cells, Cultured | Arachidonate 12-Lipoxygenase - physiology | Coronary Artery Disease - drug therapy | Reverse Transcriptase Polymerase Chain Reaction | STAT1 Transcription Factor - genetics | Blotting, Western | Mice, Knockout | Animals | Signal Transduction - drug effects | Apolipoproteins E - physiology | Arachidonate 15-Lipoxygenase - physiology | Mice | Lipids - analysis | Macrophages, Peritoneal - metabolism | Oxidases | Purines | Unsaturated fatty acids | Iron compounds | Metabolites | Molybdenum compounds | Physiological aspects | Arachidonic acid | Macrophages
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 05/2012, Volume 104, Issue 9, pp. 709 - 716
Expression of 15-lipoxygenase-1 (15-LOX-1) is decreased in many human cancers; however, the mechanistic significance of its decreased expression has been difficult to determine because its mouse homolog 12/15-LOX has opposing functions... 
LIPOXYGENASE METABOLISM | ACTIVATED RECEPTOR-GAMMA | TUMOR PROGRESSION | ONCOLOGY | COLORECTAL-CANCER | GENE-EXPRESSION | FACTOR-KAPPA-B | 15-LIPOXYGENASE-1 EXPRESSION | TERMINAL DIFFERENTIATION | INDUCE APOPTOSIS | HUMAN BREAST-CANCER | Tumor Necrosis Factor-alpha - metabolism | Up-Regulation | Colon - enzymology | Gene Expression Regulation, Neoplastic | Colonic Neoplasms - chemically induced | Immunoblotting | NF-kappa B - metabolism | RNA, Messenger - metabolism | Carcinogens | Azoxymethane | Cell Transformation, Neoplastic - genetics | Intestinal Mucosa - enzymology | Transgenes | Real-Time Polymerase Chain Reaction | Disease Models, Animal | Mice, Transgenic | Arachidonate 15-Lipoxygenase - metabolism | Cell Transformation, Neoplastic - metabolism | Gene Expression Regulation, Enzymologic | Animals | Arachidonate 15-Lipoxygenase - genetics | Epithelial Cells - enzymology | Colonic Neoplasms - enzymology | Mice | Nitric Oxide Synthase Type II - metabolism | Colon cancer | Tumor necrosis factor | Physiological aspects | Development and progression | Genetic aspects | Research | Gene expression | Risk factors | Animal models | NF- Kappa B protein | Epithelial cells | Intestine | Tumorigenesis | Epithelium | Nitric-oxide synthase | Promoters | Tumor necrosis factor- alpha | Cancer | Brief Communication
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2003, Volume 100, Issue 3, pp. 1238 - 1243
...Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesis Rainer Spanbroek* †‡ , Rolf Gra ¨ bner* † , Katharina Lo... 
T lymphocytes | Biological Sciences | Epithelial cells | Atherosclerosis | Mast cells | Leukocytes | Islets of Langerhans | Lesions | Coronary artery disease | Foam cells | Endothelial cells | Coronary heart disease | Arachidonic acid cascade | arachidonic acid cascade | DENDRITIC CELLS | MULTIDISCIPLINARY SCIENCES | LOW-DENSITY-LIPOPROTEIN | 15-LIPOXYGENASE | LANGERHANS CELLS | RECEPTOR-DEFICIENT MICE | LEUKOTRIENE C-4 | MESSENGER-RNA | EARLY ATHEROSCLEROTIC LESIONS | ENDOTHELIAL-CELLS | coronary heart disease | SMOOTH-MUSCLE CELLS | Immunohistochemistry | Antigens, Differentiation, Myelomonocytic - biosynthesis | Reticulocytes - enzymology | Arachidonate 5-Lipoxygenase - metabolism | Antigens, CD - biosynthesis | Humans | Immunoblotting | Arachidonate 5-Lipoxygenase - biosynthesis | Arachidonate 15-Lipoxygenase - metabolism | Endothelium, Vascular - enzymology | RNA, Messenger - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Leukocytes - enzymology | Macrophages - enzymology | Tissue Distribution | Cell Lineage | Phenotype | Arteries - enzymology | Kinetics | Arteriosclerosis - pathology | Aorta - enzymology | RNA - metabolism | Synthesis | Leukotrienes | Physiological aspects | Genetic aspects | Inflammation | Research | Arachidonic acid | arachidonic acid cascade‖coronary heart disease
Journal Article