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index medicus (198) 198
humans (139) 139
animals (122) 122
messenger-rna (118) 118
biochemistry & molecular biology (88) 88
low-density-lipoprotein (82) 82
arachidonate 15-lipoxygenase - genetics (78) 78
arachidonate 15-lipoxygenase - metabolism (76) 76
15-lipoxygenase (70) 70
lipoxygenase (55) 55
expression (47) 47
mice (46) 46
male (43) 43
rabbits (42) 42
cell biology (38) 38
molecular sequence data (37) 37
atherosclerotic lesions (35) 35
cells, cultured (35) 35
atherosclerosis (34) 34
rna, messenger - metabolism (34) 34
female (32) 32
arachidonic-acid (31) 31
molecular-cloning (29) 29
rna, messenger - genetics (29) 29
15-lipoxygenase messenger-rna (26) 26
arachidonate 12-lipoxygenase - genetics (26) 26
arachidonate 12-lipoxygenase - metabolism (26) 26
arachidonate 15-lipoxygenase - biosynthesis (26) 26
gene expression (26) 26
gene-expression (25) 25
base sequence (24) 24
inflammation (24) 24
peripheral vascular disease (24) 24
protein (23) 23
amino acid sequence (22) 22
endothelial-cells (22) 22
oxidation-reduction (22) 22
arachidonic acid (21) 21
reticulocyte lipoxygenase (21) 21
cells (20) 20
chromatography, high pressure liquid (20) 20
lipoproteins, ldl - metabolism (20) 20
medicine, research & experimental (20) 20
immunohistochemistry (19) 19
oxidation (19) 19
abridged index medicus (18) 18
gene expression regulation (18) 18
macrophages (18) 18
enzymes (17) 17
interleukin-4 - pharmacology (17) 17
messenger rna (17) 17
oxidative modification (17) 17
epithelial-cells (15) 15
linoleic-acid (15) 15
proteins (15) 15
apoptosis (14) 14
atherogenesis (14) 14
disease models, animal (14) 14
mammalian lipoxygenases (14) 14
reverse transcriptase polymerase chain reaction (14) 14
12/15-lipoxygenase (13) 13
15-hydroxyeicosatetraenoic acid (13) 13
arachidonate 15-lipoxygenase (13) 13
arachidonate 15-lipoxygenase - chemistry (13) 13
endocrinology & metabolism (13) 13
human atherosclerotic lesions (13) 13
mice, inbred c57bl (13) 13
mice, knockout (13) 13
oncology (13) 13
protein biosynthesis (13) 13
smooth-muscle cells (13) 13
arachidonate 15-lipoxygenase - physiology (12) 12
biophysics (12) 12
blotting, western (12) 12
multidisciplinary sciences (12) 12
research (12) 12
unsaturated fatty acids (12) 12
12-lipoxygenase (11) 11
acid (11) 11
adult (11) 11
arachidonic acid - metabolism (11) 11
arteriosclerosis - pathology (11) 11
cell line (11) 11
cell-specific 15-lipoxygenase (11) 11
cytokines (11) 11
eicosanoids (11) 11
gene (11) 11
genes (11) 11
k cq biochemistry & molecular biology (11) 11
lipid peroxidation (11) 11
lipid-protein adducts (11) 11
lipids (11) 11
middle aged (11) 11
polymerase chain reaction (11) 11
rats (11) 11
reticulocytes - enzymology (11) 11
aged (10) 10
aorta - metabolism (10) 10
arachidonate 12-lipoxygenase (10) 10
arteriosclerosis - enzymology (10) 10
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CIRCULATION, ISSN 0009-7322, 12/1995, Volume 92, Issue 11, pp. 3297 - 3303
Background 15-lipoxygenase (15-LO) may be involved in atherogenesis and in oxidative modification of LDL. In this study, we investigated 15-LO expression in... 
SUPEROXIDE DISMUTASE | MAMMALIAN LIPOXYGENASES | ATHEROSCLEROSIS | LOW-DENSITY-LIPOPROTEIN | 15-LIPOXYGENASE | CARDIOVASCULAR SYSTEM | SMOOTH-MUSCLE | POLYMERASE CHAIN REACTION | MESSENGER-RNA | OXIDATIVE MODIFICATION | DNA | SEQUENCE | POLYMERASE CHAIN-REACTION | HEMATOLOGY | SUPEROXIDE-DISMUTASE | EXPRESSION
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2003, Volume 100, Issue 3, pp. 1238 - 1243
Oxidation products of low-density lipoproteins have been suggested to promote inflammation during atherogenesis, and reticulocyte-type 15-lipoxygenase has been... 
T lymphocytes | Biological Sciences | Epithelial cells | Atherosclerosis | Mast cells | Leukocytes | Islets of Langerhans | Lesions | Coronary artery disease | Foam cells | Endothelial cells | Coronary heart disease | Arachidonic acid cascade | arachidonic acid cascade | DENDRITIC CELLS | MULTIDISCIPLINARY SCIENCES | LOW-DENSITY-LIPOPROTEIN | 15-LIPOXYGENASE | LANGERHANS CELLS | RECEPTOR-DEFICIENT MICE | LEUKOTRIENE C-4 | MESSENGER-RNA | EARLY ATHEROSCLEROTIC LESIONS | ENDOTHELIAL-CELLS | coronary heart disease | SMOOTH-MUSCLE CELLS | Immunohistochemistry | Antigens, Differentiation, Myelomonocytic - biosynthesis | Reticulocytes - enzymology | Arachidonate 5-Lipoxygenase - metabolism | Antigens, CD - biosynthesis | Humans | Immunoblotting | Arachidonate 5-Lipoxygenase - biosynthesis | Arachidonate 15-Lipoxygenase - metabolism | Endothelium, Vascular - enzymology | RNA, Messenger - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Leukocytes - enzymology | Macrophages - enzymology | Tissue Distribution | Cell Lineage | Phenotype | Arteries - enzymology | Kinetics | Arteriosclerosis - pathology | Aorta - enzymology | RNA - metabolism | Synthesis | Leukotrienes | Physiological aspects | Genetic aspects | Inflammation | Research | Arachidonic acid | Cellular biology | Neurotransmitters | Index Medicus | arachidonic acid cascade‖coronary heart disease
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 11/2014, Volume 76, pp. 147 - 162
15( )-Hydroxyeicosatetraenoic acid (15( )-HETE), the major 15-lipoxygenase 1/2 (15-LO1/2) metabolite of arachidonic acid (AA), induces CD36 expression through... 
CD36 | Foam cell | Syk | STAT1 | ROS | ATHEROSCLEROTIC LESIONS | OXIDATION | 15-LIPOXYGENASE MESSENGER-RNA | INDUCED ANGIOGENESIS | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | LOW-DENSITY-LIPOPROTEIN | CHRONIC DISEASE | SCAVENGER RECEPTOR CD36 | ENDOCRINOLOGY & METABOLISM | TYROSINE KINASE INHIBITOR | E-DEFICIENT MICE | CD36 Antigens - genetics | Immunoprecipitation | Reactive Oxygen Species - metabolism | Protein-Tyrosine Kinases - metabolism | NADPH Oxidases - metabolism | Arachidonate 12-Lipoxygenase - chemistry | Arachidonate 15-Lipoxygenase - chemistry | Male | Intracellular Signaling Peptides and Proteins - metabolism | Foam Cells - cytology | Macrophages, Peritoneal - cytology | Promoter Regions, Genetic - genetics | Foam Cells - drug effects | Focal Adhesion Kinase 2 - genetics | Protein-Tyrosine Kinases - genetics | STAT1 Transcription Factor - metabolism | CD36 Antigens - metabolism | Chromatin Immunoprecipitation | Focal Adhesion Kinase 2 - metabolism | Hydroxyeicosatetraenoic Acids - pharmacology | Coronary Artery Disease - pathology | Electrophoretic Mobility Shift Assay | Phosphorylation - drug effects | Intracellular Signaling Peptides and Proteins - genetics | Macrophages, Peritoneal - drug effects | Real-Time Polymerase Chain Reaction | Syk Kinase | Foam Cells - metabolism | Coronary Artery Disease - metabolism | RNA, Messenger - genetics | Cells, Cultured | Arachidonate 12-Lipoxygenase - physiology | Coronary Artery Disease - drug therapy | Reverse Transcriptase Polymerase Chain Reaction | STAT1 Transcription Factor - genetics | Blotting, Western | Mice, Knockout | Animals | Signal Transduction - drug effects | Apolipoproteins E - physiology | Arachidonate 15-Lipoxygenase - physiology | Mice | Lipids - analysis | Macrophages, Peritoneal - metabolism | Oxidases | Purines | Unsaturated fatty acids | Iron compounds | Metabolites | Molybdenum compounds | Physiological aspects | Arachidonic acid | Macrophages | Index Medicus
Journal Article
Journal Article