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Journal of Neurochemistry, ISSN 0022-3042, 05/2015, Volume 133, Issue 3, pp. 343 - 351
Obesity is a worldwide health problem that urgently needs to be solved. Leptin is an anti‐obesity hormone that activates satiety signals to the brain. Evidence... 
15d | PGJ | STAT | PPAR | leptin | PPAR-γ | STAT3 | 15d-PGJ
Journal Article
Frontiers in Physiology, ISSN 1664-042X, 2012, Volume 3, pp. 369 - 369
There are a wide variety of reactive species which can affect cell function, including reactive oxygen, nitrogen, and lipid species. Some are formed... 
Thiol | 15-deoxy-prostaglandin J | Redox signaling | Reactive species | 15d-PGJ | Electrophile | electrophile | thiol | redox signaling | PHYSIOLOGY | reactive species | 15-deoxy-prostaglandin J (15d-PGJ) | 15-deoxy-prostaglandin J2 (15d-PGJ2)
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2014, Volume 740, pp. 58 - 65
The aim of this study was to evaluate the peripheral effect of 15-deoxy-Δ -prostaglandin J (15d-PGJ ) in albumin-induced arthritis in temporomandibular joint... 
Temporomandibular joint | Inflammation | 15d-PGJ
Journal Article
Free Radical Research, ISSN 1071-5762, 03/2019, Volume 53, Issue 3, pp. 335 - 347
15-Hydroxyprostaglandin dehydrogenase (15-PGDH) is the key enzyme that catalyses the conversion of prostaglandin E 2 to a keto metabolite. The expression of... 
breast cancer | DNMT1 | 15-PGDH | methylation | 15d-PGJ
Journal Article
Free Radical Research, ISSN 1071-5762, 03/2019, Volume 53, Issue 3, pp. 335 - 347
15-Hydroxyprostaglandin dehydrogenase (15-PGDH) is the key enzyme that catalyses the conversion of prostaglandin E to a keto metabolite. The expression of... 
breast cancer | DNMT1 | 15-PGDH | methylation | 15d-PGJ
Journal Article
Free Radical Research, ISSN 1071-5762, 02/2014, Volume 48, Issue 2, pp. 218 - 229
Abstract The omega-6 fatty acid derivative 15-Deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2) is believed to play a role in cellular protection against oxidative... 
Oxidative stress | VSMCs | Nrf2 | 15d-PGJ | PI3K/Akt | 15d-PGJ2
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 02/2013, Volume 431, Issue 3, pp. 472 - 477
► 15d-PGJ decreased IL-13 mRNA transcription and secretion in activated T cells. ► IL-13 inhibition by 15d-PGJ is independent of PPAR-γ. ► The nuclear... 
NF-κB | IL-13 | 15d-PGJ2 | T cells | 15d-PGJ
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 12/2008, Volume 76, Issue 11, pp. 1544 - 1553
Peroxisome proliferator-activated receptor γ (PPARγ), a nuclear hormone receptor, is a ligand-activated transcription factor involved in adipogenesis, glucose... 
Angiogenesis | HO-1 | 15d-PGJ2 | VEGF | PPARγ | 15d-PGJ
Journal Article
05/2010
The acute phase of Trypanosoma cruzi infection is associated with a strong inflammatory reaction in the heart characterised by a massive infiltration of immune... 
15d-PGJ2 | Chagas disease | Trypanosoma cruzi | PPAR-gamma
Web Resource
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 07/2010, Volume 182, Issue 2, pp. 170 - 182
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 02/2011, Volume 162, Issue 3, pp. 623 - 632
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 10/2017, Volume 142, pp. 168 - 193
Diabetes mellitus is a chronic disease characterized by hyperglycemia, insulin resistance and hyperlipidemia. Glitazones or thiazolidinediones (TZD) are drugs... 
Molecular dynamics | Rosiglitazone | Docking | 15d-PGJ2 | Pioglitazone | Troglitazone
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 06/2017, Volume 8, pp. 740 - 740
15-deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) has been described as an anti-inflammatory lipid mediator in several in vitro and in vivo studies, but its effect... 
House dust mite | Lung inflammation | 15d-PGJ | Allergen | Asthma | Resolution | allergen | asthma | house dust mite | 15d-PGJ2 | resolution | lung inflammation
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 05/2014, Volume 214, Issue 1, pp. 26 - 32
This study aims to investigate the inflammatory response characteristics of liver cells caused by HBV x protein (HBx) and the unique function of the PGE... 
15d-PGJ2 | Liver cell | HBx | Apoptosis
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 10/2016, Volume 7, pp. 459 - 459
15-Deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2) is an electrophilic lipid mediator derived from PGD2 with potent anti-inflammatory effects. These are likely to be... 
Covalent modification | Atherosclerosis | Adhesion molecules | Monocyte adhesion | Inflammation | Chemokines | 15d-PGJ | Proteasome
Journal Article
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