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Molecular and Cellular Endocrinology, ISSN 0303-7207, 2006, Volume 248, Issue 1, pp. 126 - 135
Endometrial cancer is the most common malignancy of the female genital tract. Its incidence correlates with prolonged estrogen stimulation unopposed by... 
Short-chain dehydrogenase reductase | 17β-Hydroxysteroid dehydrogenase | 20α-Hydroxysteroid dehydrogenase | Aldo-keto reductase | 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE-2 | HYDROXYSTEROID DEHYDROGENASES | ER-BETA | short-chain dehydrogenase reductase | RECEPTOR-B | CELL BIOLOGY | INACTIVATION | CARCINOGENESIS | KETO REDUCTASE SUPERFAMILY | ENDOCRINOLOGY & METABOLISM | 20 alpha-hydroxysteroid dehydrogenase | aldo-keto reductase | 17 beta-hydroxysteroid dehydrogenase | EXPRESSION | CARCINOMA | HORMONES | Humans | Endometrial Neoplasms - metabolism | Hydroxyprostaglandin Dehydrogenases - metabolism | Estrogens - analysis | Endometrial Neoplasms - genetics | Isoenzymes - metabolism | 3-Hydroxysteroid Dehydrogenases - metabolism | Female | Progesterone - biosynthesis | Tumor Cells, Cultured | Estradiol - biosynthesis | Endometrium - metabolism | Progesterone - analysis | 20-Hydroxysteroid Dehydrogenases - genetics | Estrogens - biosynthesis | Endometrial Neoplasms - chemistry | Oxidoreductases - metabolism | Isoenzymes - genetics | 20-Hydroxysteroid Dehydrogenases - metabolism | Hydroxyprostaglandin Dehydrogenases - genetics | Endometrium - chemistry | Animals | Aldo-Keto Reductase Family 1 Member C3 | Estradiol Dehydrogenases | 3-Hydroxysteroid Dehydrogenases - genetics | 17-Hydroxysteroid Dehydrogenases - metabolism | Enzymes | Care and treatment | Endometrial cancer | Phenols | Hormones | Progesterone | Estradiol | Cancer
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 03/2016, Volume 472, Issue 1, pp. 231 - 236
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 06/2019, Volume 489, pp. 98 - 106
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 2004, Volume 218, Issue 1, pp. 7 - 20
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 2006, Volume 248, Issue 1, pp. 47 - 55
Journal Article
Biochemical Journal, ISSN 0264-6021, 03/2007, Volume 402, Issue 3, pp. 419 - 427
To this day, a significant proportion of the human genome remains devoid of functional characterization. In this study, we present evidence that the previously... 
Steroid metabolism | DHRS10 | 17β-hydroxysteroid dehydrogenase | Pre-receptor control | Crystal structure | Short-chain dehydrogenase/reductase | BRAIN-INJURY | 17-BETA-HYDROXYSTEROID DEHYDROGENASES | BIOCHEMISTRY & MOLECULAR BIOLOGY | short-chain dehydrogenase/reductase | WEIGHT-LOSS | SHORT-CHAIN DEHYDROGENASES/REDUCTASES | HUMAN ADIPOSE-TISSUE | steroid metabolism | crystal structure | pre-receptor control | ESTROGEN | REDUCTASE | MOLECULAR-CLONING | TYPE-1 | 17 beta-hydroxysteroid dehydrogenase | EXPRESSION | Protein Structure, Tertiary | Amino Acid Sequence | Cell Line | Gene Expression | Oxidation-Reduction | Protein Structure, Secondary | Humans | Models, Molecular | Molecular Sequence Data | Crystallography, X-Ray | Organ Specificity | Cytosol - enzymology | Sequence Alignment | 17-Hydroxysteroid Dehydrogenases - isolation & purification | 17-Hydroxysteroid Dehydrogenases - genetics | Ligands | Structural Homology, Protein | Kinetics | 17-Hydroxysteroid Dehydrogenases - chemistry | 17-Hydroxysteroid Dehydrogenases - metabolism | Binding Sites | NAD - metabolism | GFP, green fluorescent protein | RMSD, root mean square deviation | HEK-293T cells, HEK-293 cells (human embryonic kidney cells) expressing the large T-antigen of SV40 (simian virus 40) | NCS, non-crystallographic symmetry | TCEP, tris-(2-carboxyethyl)phosphine | reductase | HSD, hydroxysteroid dehydrogenase | SDR, short-chain dehydrogenase | ER, oestrogen receptor | MDR, medium-chain dehydrogenase | DHEA, dehydroepiandrosterone | short-chain dehydrogenase
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 09/2017, Volume 18, Issue 9, p. 2007
Journal Article