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18 beta-glycyrrhetinic acid (86) 86
18β-glycyrrhetinic acid (48) 48
glycyrrhetinic acid (37) 37
index medicus (32) 32
pharmacology & pharmacy (32) 32
glycyrrhizin (29) 29
glycyrrhetinic acid - pharmacology (28) 28
animals (25) 25
chemistry, medicinal (22) 22
glycyrrhetinic acid - analogs & derivatives (22) 22
licorice (18) 18
biochemistry & molecular biology (17) 17
rats (17) 17
apoptosis (16) 16
humans (15) 15
mice (15) 15
cells (14) 14
18-beta-glycyrrhetinic acid (12) 12
glycyrrhizic acid (12) 12
glycyrrhizic acid - pharmacology (11) 11
cell biology (10) 10
chemistry, organic (10) 10
expression (9) 9
inflammation (9) 9
liver (9) 9
male (9) 9
oxidative stress (9) 9
plant sciences (9) 9
glycyrrhetinic acid - chemistry (8) 8
in-vitro (8) 8
inhibition (8) 8
triterpenoids (8) 8
18 β-glycyrrhetinic acid (7) 7
activation (7) 7
cancer (7) 7
chemistry, multidisciplinary (7) 7
cytotoxicity (7) 7
18β‐glycyrrhetinic acid (6) 6
antineoplastic agents - pharmacology (6) 6
biochemistry, general (6) 6
chemistry, analytical (6) 6
dose-response relationship, drug (6) 6
food science & technology (6) 6
glycyrrhiza - chemistry (6) 6
identification (6) 6
performance liquid-chromatography (6) 6
agriculture, multidisciplinary (5) 5
antineoplastic agents - chemical synthesis (5) 5
antioxidant (5) 5
biochemical research methods (5) 5
biotechnology & applied microbiology (5) 5
cell line, tumor (5) 5
chemistry, applied (5) 5
drug screening assays, antitumor (5) 5
injury (5) 5
integrative & complementary medicine (5) 5
mechanisms (5) 5
metabolism (5) 5
neurosciences (5) 5
nf-kappa-b (5) 5
organic chemistry (5) 5
structure-activity relationship (5) 5
synthesis (5) 5
toxicology (5) 5
18 alpha-glycyrrhetinic acid (4) 4
agents (4) 4
anti-inflammation (4) 4
anti-tumor activity (4) 4
antihepatotoxic activity (4) 4
antineoplastic agents - chemistry (4) 4
biomedicine (4) 4
biotechnology (4) 4
cell proliferation - drug effects (4) 4
cells, cultured (4) 4
chemistry (4) 4
chronic hepatitis-c (4) 4
female (4) 4
gap junctions - drug effects (4) 4
glycyrrhetinic acid - chemical synthesis (4) 4
glycyrrhetinic acid - metabolism (4) 4
lipopolysaccharide (4) 4
medicine, research & experimental (4) 4
metastasis (4) 4
microbiology (4) 4
molecular conformation (4) 4
nitric-oxide (4) 4
plant extracts - pharmacology (4) 4
products (4) 4
proliferation (4) 4
18 beta-glycyrrhetinic acid derivatives (3) 3
18^b-glycyrrhetinic acid (3) 3
18α-glycyrrhetinic acid (3) 3
analysis (3) 3
animal anatomy / morphology / histology (3) 3
betulinic acid (3) 3
biological-fluids (3) 3
biotransformation (3) 3
cloning (3) 3
conversion (3) 3
dementia (3) 3
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JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, ISSN 1010-6030, 01/2007, Volume 185, Issue 2-3, pp. 271 - 276
The interaction of 18 beta-glycyrrhetinic acid (GA): The metabolite of glycyrrhizic acid which is the main active component of a commonly used traditional... 
binding sites | 18 beta-glycyrrhetinic acid | fluorescence quenching | CHEMISTRY, PHYSICAL | PROTEIN-BINDING | FLAVONOIDS | serum albumin-drug interactions | OXYGEN | IN-VITRO | INHIBITION | FLUORESCENCE | GLYCYRRHETINIC ACID | LIVER | ENERGY-TRANSFER | GLYCYRRHIZIN | bovine serum albumin
Journal Article
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ISSN 0006-291X, 04/2012, Volume 420, Issue 4, pp. 805 - 810
18 beta-Glycyrrhetinic acid (18 beta-GA) obtained from the herb liquorice has various pharmacological properties including anti-inflammatory and anti-bacterial... 
ADIPOSE TRIGLYCERIDE LIPASE | HORMONE-SENSITIVE LIPASE | LIPID-METABOLISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | MITOTIC CLONAL EXPANSION | 18 beta-Glycyrrhetinic acid | Lipolysis | 3T3-L1 preadipocytes | SKELETAL-MUSCLE | IN-VITRO | OBESITY | BIOPHYSICS | FAT | ADIPOCYTE DIFFERENTIATION | Adipogenesis | TRANSGENIC MICE
Journal Article
by Wu, SY and Cui, SC and Wang, L and Zhang, YY and Yan, XX and Lu, HL and Xing, GZ and Ren, J and Gong, LK
ACTA PHARMACOLOGICA SINICA, ISSN 1671-4083, 12/2018, Volume 39, Issue 12, pp. 1865 - 1873
Cholestasis is a common feature of liver injury, which manifests as bile acid excretion and/or enterohepatic circulation disorders. However, very few effective... 
FXR | TRANSPORTERS | hepatoprotective effect | bile acid transporters | NAPHTHYL ISOTHIOCYANATE | SANDWICH-CULTURED RAT | CHEMISTRY, MULTIDISCIPLINARY | INDUCED LIVER-INJURY | cholestatic liver injury | DELETION | 18 beta-glycyrrhetinic acid (18b-GA) | GLYCYRRHETINIC ACID | PHARMACOLOGY & PHARMACY | Sirt1 | GLYCYRRHIZIN | EXPRESSION | BILE-ACIDS
Journal Article
Journal Article
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 08/2010, Volume 58, Issue 15, pp. 8623 - 8629
Journal Article
by Park, M and Lee, JH and Choi, JK and Hong, YD and Bae, IH and Lim, KM and Park, YH and Ha, H
MOLECULAR NUTRITION & FOOD RESEARCH, ISSN 1613-4125, 07/2014, Volume 58, Issue 7, pp. 1436 - 1446
Scope: Previous reports suggest that licorice extract has various metabolically beneficial effects and may help to alleviate adiposity and hyperlipidemia.... 
Obesity | CARDIOMETABOLIC RISK | 18 beta-glycyrrhetinic acid | FOOD-INTAKE | FOOD SCIENCE & TECHNOLOGY | ENDOCANNABINOID SYSTEM | RECEPTOR | Licorice | ENERGY-BALANCE | BODY-WEIGHT | ANTAGONIST SR141716 | Cannabinoid receptor type 1 | PPAR-GAMMA | DIFFERENTIATION | GLYCYRRHIZA-GLABRA | 3T3-L1
Journal Article
Journal of Inorganic Biochemistry, ISSN 0162-0134, 05/2018, Volume 182, pp. 194 - 199
Metal-arene complexes containing bioactive natural-product derived ligands can have new and unusual properties. We report the synthesis, characterization and... 
Anticancer | Ru(II) arene complexes | 18β-Glycyrrhetinic acid | ACTIVATION | NONBOND INTERACTIONS | BIOCHEMISTRY & MOLECULAR BIOLOGY | RUTHENIUM | MECHANISMS | 18 beta-Glycyrrhetinic acid | ORGANOMETALLIC ANTICANCER COMPLEXES | CHEMISTRY, INORGANIC & NUCLEAR | IN-VITRO | ARENE COMPLEXES | DNA | CYTOTOXICITY | METAL-COMPLEXES
Journal Article
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, ISSN 1382-6689, 06/2018, Volume 60, pp. 82 - 90
Journal Article
by Lee, CS and Kim, YJ and Lee, MS and Han, ES and Lee, SJ
LIFE SCIENCES, ISSN 0024-3205, 09/2008, Volume 83, Issue 13-14, pp. 481 - 489
Defects in mitochondrial function have been shown to participate in the induction of cell death in cancer cells. The present study was designed to assess the... 
MEDICINE, RESEARCH & EXPERIMENTAL | OXIDATIVE STRESS | 18 beta-glycyrrhetinic acid | cell death | CANCER CELLS | MITOMYCIN-C | INVOLVEMENT | mitochondrial membrane permeability change | INDUCTION | SiHa cells | PROMYELOTIC LEUKEMIA | MITOCHONDRIAL DAMAGE | LIVER | antibiotic cancer drugs | PHARMACOLOGY & PHARMACY | GLYCYRRHETIC ACID | CYTOTOXICITY
Journal Article
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 02/2015, Volume 63, Issue 4, pp. 1200 - 1209
The clinical use of antineoplastic drug cisplatin (CP) is commonly complicated by nephrotoxic side effects that limit its application and therapeutic... 
anti-inflammation | nephrotoxicity | cisplatin | glycyrrhizic acid | 18β-glycyrrhetinic acid | TARGET | OXIDATIVE STRESS | FOOD SCIENCE & TECHNOLOGY | INJURY | RATS | QUERCETIN | 18 beta-glycyrrhetnic acid | AMIFOSTINE | INFLAMMATION | AGRICULTURE, MULTIDISCIPLINARY | CHEMISTRY, APPLIED
Journal Article
by Lee, KW and Ho, WS
PROTEIN AND PEPTIDE LETTERS, ISSN 0929-8665, 12/2013, Volume 20, Issue 12, pp. 1360 - 1364
UDP-glucuronosyltransferase (UDP) catalyzes a broad spectrum of endobiotic and xenobiotics. It is the isoform of the UGT1 family, which are made from the... 
DIFFERENTIAL INDUCTION | expression | 18 beta-glycyrrhetinic acid | GENE SUPERFAMILY | transcription | BIOCHEMISTRY & MOLECULAR BIOLOGY | THYROXINE | IDENTIFICATION | BILIRUBIN | induction | CLONING | AH-RECEPTOR | LIVER | OLTIPRAZ | UGT1A8
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 10/2017, Volume 25, Issue 20, pp. 5441 - 5451
Journal Article
ANTICANCER RESEARCH, ISSN 0250-7005, 06/2011, Volume 31, Issue 6, pp. 2209 - 2215
Background: UVB radiation is the major etiological factor in the pathogenesis of skin aging and cancer development. New approaches to prevent and reverse UVB... 
UVB | PATHWAYS | CELLS | APOPTOSIS | 18 beta-glycyrrhetinic acid | CANCER | RADIATION | DAMAGE | FIBROBLASTS | REACTIVE OXYGEN | ONCOLOGY | normal human keratinocytes | LICORICE | ROS | glabridin | SKIN
Journal Article
by Zhang, M and Chang, Z and Zhao, F and Zhang, P and Hao, YJ and Yan, L and Liu, N and Wang, JL and Bo, L and Ma, P and Zhou, W and Ma, X and Xu, QB and Zhou, R
FRONTIERS IN PHARMACOLOGY, ISSN 1663-9812, 01/2019, Volume 10, p. 13
Pulmonary arterial hypertension (PAH) is a destructive and rare disorder characterized by a progressive increase in pulmonary artery pressure and... 
SURVIVAL | NADPH OXIDASE | APOPTOSIS | SUPEROXIDE | 18 beta-glycyrrhetinic acid | monocrotaline | INJURY | REACTIVE OXYGEN | ANTIOXIDANT | PHARMACOLOGY & PHARMACY | pulmonary arterial hypertension | nicotinamide adenine dinucleotide phosphate oxidase | oxidative stress | 18β-glycyrrhetinic acid
Journal Article
by Chen, X and Zhi, X and Yin, ZF and Li, XQ and Qin, LJ and Qiu, ZL and Su, JC
FRONTIERS IN PHARMACOLOGY, ISSN 1663-9812, 06/2018, Volume 9
Bone metabolism is determined by a delicate balance between bone resorption by osteoclasts and bone formation by osteoblasts. The imbalance due to... 
RANKL | ACTIVATION | 18 beta-glycyrrhetinic acid | RESORPTION | MAPK signaling pathway | NFATC1 | SUPPRESSION | OSTEOPOROSIS | COMMITMENT | TRAF6 | GLYCYRRHETINIC ACID | PHARMACOLOGY & PHARMACY | MICE | DIFFERENTIATION | osteoclastogenesis | INDUCED BONE LOSS
Journal Article
by Kim, SH and Hong, JH and Lee, JE and Lee, YC
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, ISSN 1382-6689, 06/2017, Volume 52, pp. 99 - 113
18 beta-Glycyrrhetinic acid (18Gly), the major bioactive component of Glycyrrhizae Radix, possesses anti ulcerative, anti-inflammatory, and other... 
OXIDATIVE STRESS | 18 beta-glycyrrhetinic acid | ACTIVATED RECEPTOR-GAMMA | IL-5 | IL-13 | GATA-3 | Asthma | MURINE MODEL | ENVIRONMENTAL SCIENCES | EXPERIMENTAL ALLERGIC-ASTHMA | IMMUNE-RESPONSES | LICORICE | REGULATORY T-CELLS | PHARMACOLOGY & PHARMACY | MICE | TOXICOLOGY | Foxp3 | NF-KAPPA-B | UP-REGULATION
Journal Article
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