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192 igg-saporin (273) 273
neurosciences (254) 254
animals (249) 249
rats (214) 214
male (182) 182
basal forebrain (124) 124
ribosome inactivating proteins, type 1 (124) 124
acetylcholine (109) 109
n-glycosyl hydrolases (109) 109
alzheimers-disease (103) 103
index medicus (86) 86
rats, sprague-dawley (69) 69
hippocampus (62) 62
memory (62) 62
acetylcholine - metabolism (58) 58
choline o-acetyltransferase - metabolism (58) 58
antibodies, monoclonal - toxicity (57) 57
saporins (56) 56
immunotoxins - toxicity (54) 54
neurons (53) 53
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ngf receptor (49) 49
rats, long-evans (49) 49
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brain (44) 44
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rats, wistar (37) 37
injections, intraventricular (35) 35
neurons - physiology (35) 35
cholinergic agents - pharmacology (33) 33
cholinergic agents - toxicity (32) 32
hippocampus - metabolism (32) 32
maze learning - physiology (32) 32
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humans (31) 31
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cholinergic fibers - physiology (30) 30
prosencephalon - physiology (30) 30
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immunotoxins (29) 29
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attention (28) 28
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neurons - drug effects (28) 28
acetylcholine - physiology (27) 27
memory - physiology (27) 27
time factors (27) 27
cerebral-cortex (26) 26
cholinergic fibers - drug effects (26) 26
denervation (26) 26
neurology (26) 26
prosencephalon - drug effects (25) 25
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pharmacology & pharmacy (24) 24
192 igg‐saporin (23) 23
behavior, animal - physiology (23) 23
learning (23) 23
prosencephalon - cytology (22) 22
behavior, animal - drug effects (21) 21
disease models, animal (21) 21
medial septal area (21) 21
192 igg saporin (20) 20
192-igg-saporin (20) 20
excitotoxic lesions (20) 20
medial prefrontal cortex (20) 20
prefrontal cortex (20) 20
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cholinergic agents (19) 19
cholinergic basal forebrain (19) 19
growth-factor receptor (19) 19
life sciences (19) 19
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immunotoxins - administration & dosage (18) 18
long-term potentiation (18) 18
acetylcholinesterase - metabolism (17) 17
cholinergic fibers - metabolism (17) 17
immunoglobulin g (17) 17
mice (17) 17
neural pathways - physiology (17) 17
selective immunotoxic lesions (17) 17
water maze (17) 17
antibodies, monoclonal - administration & dosage (16) 16
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Current Topics in Behavioral Neurosciences, ISSN 1866-3370, 2016, Volume 29, pp. 111 - 123
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 03/2002, Volume 22, Issue 5, pp. 1905 - 1913
Journal Article
Journal Article
Behavioural Brain Research, ISSN 0166-4328, 12/2008, Volume 195, Issue 2, pp. 231 - 238
Journal Article
Neuroscience Letters, ISSN 0304-3940, 03/2007, Volume 415, Issue 2, pp. 97 - 101
Degeneration of cholinergic neurons is a well known characteristic of Alzheimer's disease (AD). Two radioligands were studied in a rat model of cholinergic... 
192 IgG-saporin | IBVM | I-A-85380 | Vesicular acetylcholine transporter | Nicotinic acetylcholine receptor
Journal Article
Pharmacology, Biochemistry and Behavior, ISSN 0091-3057, 2002, Volume 72, Issue 4, pp. 899 - 912
In a previous experiment [Eur J Neurosci 12 (2000) 79], combined intracerebroventricular injections of 5,7-dihydroxytryptamine (5,7-DHT; 150 μg) and 192... 
192 IgG-saporin | Locomotion | Motor | Memory | Sex | Water maze | Basal forebrain | Beam-walking | Radial maze | T-maze | 5,7-DHT | Raphe | motor | memory | WATER-MAZE | water maze | ALZHEIMERS-DISEASE | locomotion | CHOLINERGIC SYSTEM | NUCLEUS BASALIS MAGNOCELLULARIS | SEROTONIN DEPLETION | BEHAVIORAL SCIENCES | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | radial maze | basal forebrain | sex | AMPA-INDUCED LESIONS | LOCOMOTOR-ACTIVITY | raphe | beam-walking | NEUROSCIENCES | SEX-DIFFERENCES | RADIAL-ARM MAZE | Antibodies, Monoclonal - toxicity | Brain Chemistry - drug effects | Immunotoxins - toxicity | Serotonin - physiology | Rats, Long-Evans | Injections, Intraventricular | Saporins | Motor Activity - drug effects | Male | Postural Balance - drug effects | Hippocampus - drug effects | Cerebral Cortex - metabolism | Brain Diseases - chemically induced | Immunotoxins - administration & dosage | 5,7-Dihydroxytryptamine - administration & dosage | Neostriatum - drug effects | Behavior, Animal - drug effects | Neostriatum - metabolism | N-Glycosyl Hydrolases | Cerebral Cortex - drug effects | Prosencephalon - pathology | Ribosome Inactivating Proteins, Type 1 | Rats | Memory, Short-Term - drug effects | 5,7-Dihydroxytryptamine - toxicity | Maze Learning - drug effects | Stereotaxic Techniques | Hippocampus - metabolism | Animals | Brain Diseases - pathology | Antibodies, Monoclonal - administration & dosage | Histocytochemistry | Acetylcholinesterase - metabolism
Journal Article
Brain Research, ISSN 0006-8993, 2003, Volume 969, Issue 1, pp. 147 - 159
Journal Article
Experimental Brain Research, ISSN 0014-4819, 5/1999, Volume 126, Issue 2, pp. 270 - 280
Journal Article
Journal Article
Neuroscience Letters, ISSN 0304-3940, 2007, Volume 415, Issue 2, pp. 97 - 101
Degeneration of cholinergic neurons is a well known characteristic of Alzheimer's disease (AD). Two radioligands were studied in a rat model of cholinergic... 
192 IgG-saporin | IBVM | Nicotinic acetylcholine receptor | I-A-85380 | Vesicular acetylcholine transporter
Journal Article
Journal Article
Journal of Neuroscience Methods, ISSN 0165-0270, 1999, Volume 91, Issue 1, pp. 9 - 19
Journal Article
European Journal of Neuroscience, ISSN 0953-816X, 01/2000, Volume 12, Issue 1, pp. 67 - 79
This study assessed behavioural and neurochemical effects of i.c.v. injections of both the cholinergic toxin 192 IgG‐saporin (2 μg) and the serotonergic toxin... 
beam walking | T‐maze alternation | motor | memory | water‐maze | 192 IgG‐saporin | basal forebrain | locomotion | raphe | 7‐DHT | radial‐maze | 192 IgG-saporin | Locomotion | T-maze alternation | Water-maze | Motor | Memory | Basal forebrain | Beam walking | Radial-maze | 5,7-DHT | Raphe | PURKINJE-CELLS | ALZHEIMERS-DISEASE | AMPA-INDUCED LESIONS | SHORT-TERM-MEMORY | NEUROSCIENCES | water-maze | GROWTH-FACTOR RECEPTOR | SPATIAL PERFORMANCE | WATER MAZE | NUCLEUS BASALIS MAGNOCELLULARIS | SELECTIVE REMOVAL | radial-maze | CENTRAL-NERVOUS-SYSTEM | Antibodies, Monoclonal - toxicity | Immunotoxins - toxicity | Memory - drug effects | Frontal Lobe - metabolism | Rats, Long-Evans | Cholinergic Agents - toxicity | Saporins | Motor Activity - drug effects | Acetylcholine - metabolism | Parietal Lobe - metabolism | Brain - physiology | Corpus Striatum - metabolism | Serotonin Agents - toxicity | Female | N-Glycosyl Hydrolases | Dopamine - metabolism | Locomotion - drug effects | Ribosome Inactivating Proteins, Type 1 | Rats | Hydroxyindoleacetic Acid - metabolism | 5,7-Dihydroxytryptamine - toxicity | Maze Learning - drug effects | Brain - drug effects | Hippocampus - metabolism | Animals | Norepinephrine - metabolism | Serotonin - metabolism | Brain - pathology | Biogenic Monoamines - metabolism | Life Sciences | Neurons and Cognition | Neurobiology
Journal Article
Journal Article