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Bioorganic and Medicinal Chemistry Letters, ISSN 0960-894X, 05/2012, Volume 22, Issue 10, pp. 3567 - 3570
This Letter presents the synthesis and biological evaluation of a collection of 2-aminothiazoles as a novel class of compounds with the capability to reduce... 
2-Aminothiazoles | Colon cancer | COX-2 | PGE
Journal Article
Tetrahedron, ISSN 0040-4020, 12/2018, Volume 74, Issue 50, pp. 7143 - 7147
A novel and efficient reaction has been developed to synthesize a set of substituted 2-aminothiazoles from α-nitroepoxides and ammonium thiocyanate. This... 
2-Aminothiazoles | Ammonium thiocyanate | Facile synthesis | α-Nitroepoxides | SCHIFF-BASES | CHEMISTRY, ORGANIC | alpha-Nitroepoxides | INHIBITORS | DERIVATIVES | DISCOVERY
Journal Article
by Zhu, ZZ and Tang, XD and Cen, JH and Li, JX and Wu, WQ and Jiang, HF
CHEMICAL COMMUNICATIONS, ISSN 1359-7345, 04/2018, Volume 54, Issue 30, pp. 3767 - 3770
A novel copper-catalyzed annulation of oxime acetates and xanthates for the synthesis of thiazol-2-yl ethers with remarkable regioselectivity has been... 
VINYL AZIDES | POTASSIUM THIOCYANATE | EFFICIENT SYNTHESIS | 2-AMINOTHIAZOLES | INHIBITORS | C-H FUNCTIONALIZATION | CASCADE ANNULATION | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY | INTERNAL OXIDANTS | ACCESS
Journal Article
Asian Journal of Chemistry, ISSN 0970-7077, 07/2015, Volume 27, Issue 11, pp. 4081 - 4084
Journal Article
Organic Process Research & Development, ISSN 1083-6160, 09/2013, Volume 17, Issue 9, pp. 1183 - 1191
The development of a tube-in-tube reactor based on a semipermeable polymer membrane has enabled the efficient transfer of gases into liquid flow streams. In... 
DESIGN | TRANSPORT | HYDROGENATION | TEMPERATURE-DEPENDENCE | PERMEABILITY | RECOGNITION | MOLECULE | CHEMISTRY, ORGANIC | GLUCOKINASE ACTIVATORS | CONVENIENT | 2-AMINOTHIAZOLES | CHEMISTRY, APPLIED
Journal Article
Tetrahedron, ISSN 0040-4020, 09/2016, Volume 72, Issue 35, pp. 5285 - 5289
An efficient synthesis of 2,4,5-trisubstituted thiazoles via the reaction of α-nitroepoxides and thioureas under mild conditions has been developed. This... 
2,4,5-Trisubstituted thiazoles | Facile synthesis | Thioureas | α-Nitroepoxides | SUPPORTED REAGENTS | ONE-POT SYNTHESIS | CHEMISTRY, ORGANIC | alpha-Nitroepoxides | 2-AMINOTHIAZOLES | AGENTS | INHIBITORS
Journal Article
Tetrahedron, ISSN 0040-4020, 2008, Volume 64, Issue 22, pp. 5019 - 5022
A highly efficient and facile method has been described for the synthesis of substituted 2-aminothiazoles in water without any added catalyst or co-organic... 
Water | 2-Aminothiazoles | Environment-friendly synthesis | Ambient temperature | PHASE SYNTHESIS | SERIES | DIELS-ALDER REACTIONS | ANALOGS | CHEMISTRY, ORGANIC | ambient temperature | water | THIAZOLES | 2-aminothiazoles | AMINOTHIAZOLES | INHIBITORS | environment-friendly synthesis | DERIVATIVES
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 2016, Volume 14, Issue 29, pp. 7061 - 7068
New 5-azo substituted thiazole derivatives have been obtained, under mild conditions and in good yields, by the reaction between 2-N-pyrrolidinylthiazole and a... 
DESIGN | ARENEDIAZONIUM SALTS | ELECTROPHILICITY | COUPLING REACTIONS | COMPLEXES | CHEMISTRY, ORGANIC | NUCLEOPHILICITY | 2-AMINOTHIAZOLES | DERIVATIVES
Journal Article
Organic & Biomolecular Chemistry, ISSN 1477-0520, 2016, Volume 14, Issue 29, pp. 7061 - 7068
New 5-azo substituted thiazole derivatives have been obtained, under mild conditions and in good yields, by the reaction between 2-N-pyrrolidinylthiazole and a... 
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 02/2017, Volume 127, pp. 859 - 873
Prion diseases are serious, not curable neurodegenerative disorders caused by the accumulation of the misfolded protein PrP that represents the pathological... 
3D-QSAR | Anti-Prion agents | Pharmacophore modeling | Theranostic tools | Prion | CHEMISTRY, MEDICINAL | PROTEIN | MECHANISM | IN-SILICO | 2-AMINOTHIAZOLES | DISCOVERY | POTENT | ACCURATE DOCKING | BIOLOGY | CREUTZFELDT-JAKOB-DISEASE | INHIBITORS | Index Medicus
Journal Article
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, ISSN 0960-894X, 05/2012, Volume 22, Issue 10, pp. 3567 - 3570
This Letter presents the synthesis and biological evaluation of a collection of 2-aminothiazoles as a novel class of compounds with the capability to reduce... 
CHEMISTRY, MEDICINAL | Colon cancer | COX-2 | 2-Aminothiazoles | CHEMISTRY, ORGANIC | MPGES-1 | HALLMARKS | PGE
Journal Article
Chemical Communications, ISSN 1359-7345, 2018, Volume 54, Issue 30, pp. 3767 - 3770
A novel copper-catalyzed annulation of oxime acetates and xanthates for the synthesis of thiazol-2-yl ethers with remarkable regioselectivity has been... 
MATERIALS SCIENCE, BIOMATERIALS | VINYL AZIDES | POTASSIUM THIOCYANATE | EFFICIENT SYNTHESIS | 2-AMINOTHIAZOLES | INHIBITORS | C-H FUNCTIONALIZATION | CASCADE ANNULATION | DERIVATIVES | INTERNAL OXIDANTS | ACCESS | Organic chemistry | Additives | Ketones | Regioselectivity | Aromatic compounds | Chemical reactions | Copper | Ethers | Chemical synthesis | Acetates
Journal Article
MOLECULES, ISSN 1420-3049, 11/2019, Volume 24, Issue 21, p. 3846
A catalyst-free heterocyclization reaction of alpha-chloroglycinates with thiobenzamides or thioureas leading to 2,4-disubstituted-5-acylamino-1,3-thiazoles... 
SYSTEM | BIOCHEMISTRY & MOLECULAR BIOLOGY | 2-AMINOTHIAZOLES | 3-thiazoles | RELEASE | 5-acylamino-1 | CHEMISTRY, MULTIDISCIPLINARY | alpha-chloroglycinates | CONSTRUCTION | AMIDOALKYLATION | Hantzsch reaction | DERIVATIVES | EFFICIENT | hantzsch reaction | 5-acylamino-1,3-thiazoles | α-chloroglycinates
Journal Article
Bioorganic and Medicinal Chemistry Letters, ISSN 0960-894X, 11/2011, Volume 21, Issue 21, pp. 6500 - 6504
Synthesis, SAR and physico-chemical properties of an alkyl aminothiazole series 8 and 16are described. 2-Pyridylaminothiazole based compounds such as 8c and... 
Inhibition of cPP induced feeding | Sulfamides | NPY5 antagonists | 5-(20-Pyridyl)-2-aminothiazoles | Sulfonamides | CHEMISTRY, MEDICINAL | FOOD-INTAKE | FEEDING-BEHAVIOR | CHEMISTRY, ORGANIC | 5-(2 '-Pyridyl)-2-aminothiazoles | DISCOVERY | NEUROPEPTIDE-Y
Journal Article
Synthesis, ISSN 0039-7881, 12/2018, Volume 50, Issue 24, pp. 4867 - 4874
Abstract A simple and efficient one-pot protocol has been developed for the synthesis of thiazole derivatives from readily available starting materials.... 
paper | thiourea | heterocycles | pot-ecomomy | thiazole | condensation | tribromoisocyanuric acid | quinoxaline | green chemistry | ISOTHIOCYANATES | REAGENT | SYSTEM | DESIGN | ACID/TRIPHENYLPHOSPHINE | N-PHENYLUREAS | CHEMISTRY, ORGANIC | 2-AMINOTHIAZOLES | GREEN | FACILE SYNTHESIS | CHEMISTRY
Journal Article
by Zhu, Y and Chen, WT and Zhao, DH and Zhang, GL and Yu, YP
SYNTHESIS-STUTTGART, ISSN 0039-7881, 05/2019, Volume 51, Issue 9, pp. 2023 - 2029
Polysubstituted 2-aminothiazoles have been synthesized via a one-pot three-component reaction of -nitro epoxides, potassium thiocyanate, and primary amines... 
DESIGN | NITROEPOXIDES | primary amines | CHEMISTRY, ORGANIC | nitro epoxides | THIAZOLES | 2-aminothiazoles | DISCOVERY | potassium thiocyanate | IN-VITRO | BENZAMIDES | BIOLOGICAL-ACTIVITY | INHIBITORS | one-pot synthesis | DERIVATIVES | EFFICIENT
Journal Article
CHEMISTRY OF HETEROCYCLIC COMPOUNDS, ISSN 0009-3122, 04/2014, Volume 50, Issue 1, pp. 103 - 110
We have developed an effective synthetic method and prepared several 4-hydroxy-1-methyl-2,2-dioxo-N-(1,3-thiazol-2-yl)-1De-2... 
amides | esters | CHEMISTRY, ORGANIC | analgesic activity | ACID ALKYLAMIDES | 2,1-benzothiazines | 2-aminothiazoles
Journal Article
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