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2-arachidonylglycerol (309) 309
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Annual Review of Neuroscience, ISSN 0147-006X, 07/2012, Volume 35, pp. 529 - 529
Despite being regarded as a hippie science for decades, cannabinoid research has finally found its well-deserved position in mainstream neuroscience. A series... 
2-Arachidonylglycerol
Journal Article
Recent Patents on CNS Drug Discovery, ISSN 1574-8898, 04/2012, Volume 7, Issue 1, pp. 25 - 40
Rich evidence has shown that cannabis products exert a broad gamut of effects on emotional regulation. The main psychoactive ingredient of hemp, Delta... 
2-Arachidonylglycerol
Journal Article
Recent Patents on CNS Drug Discovery, ISSN 1574-8898, 04/2012, Volume 7, Issue 1, pp. 49 - 70
Endocannabinoids are lipid transmitters binding and activating the cannabinoid receptors. Both cannabinoid receptors and endocannabinoids, such as... 
2-Arachidonylglycerol
Journal Article
Neuroreport, ISSN 0959-4965, 04/2000, Volume 11, Issue 6, pp. 1231 - 1235
The human astrocytoma cell line CCF-STTG1 accumulates [ super(3)H]2-AG through an Na super(+)- and energy-independent process, with a K sub(m) of 0.7 plus or... 
2-Arachidonylglycerol
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 1 - 1
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. 
Spinal cord | Calcium mobilization | Calcium (intracellular) | 2-Arachidonylglycerol | Astrocytes | Receptor mechanisms | Cannabinoid CB1 receptors
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 07/2013, Volume 126, Issue 1, pp. 29 - 36
2‐arachidonyl glycerol (2‐AG) allosterically potentiates GABAA receptors via a binding site located in transmembrane segment M4 of the β2 subunit. Two amino... 
GABA | 2‐arachidonylglycerol (2‐AG) | endocannabinoids | GABAA receptors | 2-arachidonylglycerol (2-AG) | receptors
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 09/2018, Volume 43, Issue 10, pp. 2056 - 2063
Prominent motor deficits (e.g., chorea) that typify Huntington’s disease (HD) arise following a prolonged prodromal stage characterized by psychiatric... 
Huntingtons disease | Emotional behavior | Neurosciences | Dopamine | Chorea | Nervous system | Huntington's disease | Apathy | Degradation | 2-Arachidonylglycerol | Motivation | Coding | Rodents | Reinforcement | Inhibition | Dopamine receptors
Journal Article
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, ISSN 0193-1849, 10/2018, Volume 315, Issue 4, pp. E489 - E495
Intestinal production of endocannabinoid and oleoylethanolamide (OEA) is impaired in highfat diet/obese rodents, leading to reduced satiety. Such diets also... 
ACTIVATION | PHYSIOLOGY | RISK-FACTORS | RECEPTOR | GUT MICROBIOTA | OLEOYLETHANOLAMIDE | DIET-INDUCED OBESITY | inflammation tight-junction proteins | FAT INTAKE | INSULIN | REDUCTION | DYSREGULATION | ENDOCRINOLOGY & METABOLISM | n-acylethanolamines | anandamide | intestinal fat sensors | 2-arachidonylglycerol
Journal Article
Organic & Biomolecular Chemistry, ISSN 1477-0520, 01/2018, Volume 16, Issue 29, pp. 5250 - 5253
Diacylglycerol lipases (DAGL) produce the endocannabinoid 2-arachidonoylglycerol, a key modulator of neurotransmitter release. Chemical tools that visualize... 
Proteins | Urea | Organic chemistry | Neurotransmitter release | 2-Arachidonylglycerol | Profiling | Diacylglycerol | Lipoprotein lipase | Lipase
Journal Article
Journal Article
Journal of Animal Science, ISSN 0021-8812, 10/2016, Volume 94, pp. 716 - 717
Endocannabinoids, including anandamide (AEA) and 2-arachidonoylglycerol (2-AG), are a class of endogenous lipid mediators that activate cannabinoids receptors... 
Energy metabolism | Correlation | Composition | Lipids | Metabolism | Chemical compounds | Anandamide | Studies | Receptors | 2-Arachidonylglycerol | Cattle | Mathematical analysis | Feeds | Feed efficiency | Finishing
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 890 - 12
Human alpha/beta hydrolase domain 6 (hABHD6) is an enzyme that hydrolyzes 2-arachidonoylglycerol (2-AG), a potent agonist at both cannabinoid CB1 and CB2... 
PROFILE | ENZYMES | MULTIDISCIPLINARY SCIENCES | ABHD6 | INHIBITORS | PROTEINS | HUMAN MONOACYLGLYCEROL LIPASE | DELETION | Carbamylation | Enzymes | Hydrolase | Therapeutic applications | Serine | Methionine | Ions | Mass spectroscopy | Proteins | Trypsin | 2-Arachidonylglycerol | Affinity chromatography | Post-translation | Cannabinoid CB2 receptors | Catalysis | Protein structure
Journal Article
Journal of Immunology, ISSN 0022-1767, 04/2017, Volume 198, Issue 8, pp. 3255 - 3263
The endocannabinoids 2-arachidonoyl-glycerol and N-arachidonoyl-ethanolamine mediate an array of pro- and anti-inflammatory effects. These effects are related,... 
Ethanolamine | Leukocyte migration | Neutrophils | Glycerol | Prostaglandin E2 | Biosynthesis | Superoxide | Leukocytes (neutrophilic) | Pharmacology | Inflammation | Lipase | Metabolism | Prostaglandin endoperoxide synthase | Hydrolysis | Receptors | 2-Arachidonylglycerol | Leukotriene B4 | Cyclooxygenase-2
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2018, Volume 115, Issue 45, p. E10720
Adequate pain management remains an unmet medical need. We previously revealed an opioid-independent analgesic mechanism mediated by orexin 1 receptor... 
Pain perception | Orexins | Opioid receptors | Neurons | Periaqueductal gray area | Stimulation | Hypothalamus | Neuropathy | Electrical stimuli | Analgesia | Receptors | γ-Aminobutyric acid | Pain | 2-Arachidonylglycerol | Analgesics | Antagonist drugs | Pain management | Median nerve | Needles | Mice | Acupuncture | Lidocaine | c-Fos protein
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 11/2019, Volume 9, Issue 1, pp. 1 - 8
Brain trauma was clinically associated with increased osteogenesis in the appendicular skeleton. We showed previously in C57BL/6J mice that mild traumatic... 
SYSTEM | HEAD-INJURY | DEFECTS | CB1 | MULTIDISCIPLINARY SCIENCES | MAST-CELLS | INDUCED INFLAMMATION | OSTEOGENESIS | Femur | Traumatic brain injury | Cannabinoid CB1 receptors | Trauma | Anandamide | Bone growth | Calvaria | 2-Arachidonylglycerol | Computed tomography | Inverse agonists | Degranulation | Skull | Skeleton | Porosity | Osteogenesis
Journal Article
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