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index medicus (172) 172
isoprenoid biosynthesis (154) 154
escherichia-coli (130) 130
nonmevalonate pathway (123) 123
biochemistry & molecular biology (104) 104
isopentenyl diphosphate (102) 102
1-deoxy-d-xylulose 5-phosphate reductoisomerase (96) 96
biosynthesis (94) 94
2-c-methyl-d-erythritol 4-phosphate pathway (92) 92
2-c-methyl-d-erythritol 4-phosphate (91) 91
terpenoid biosynthesis (74) 74
non-mevalonate pathway (67) 67
erythritol - analogs & derivatives (64) 64
enzymes (60) 60
terpenes - metabolism (58) 58
erythritol - metabolism (54) 54
mevalonate-independent pathway (54) 54
phosphates (51) 51
methylerythritol phosphate-pathway (50) 50
physiological aspects (47) 47
plant sciences (47) 47
4--2-c-methyl-d-erythritol (45) 45
molecular sequence data (45) 45
chemistry, organic (44) 44
isoprenoids (43) 43
amino acid sequence (40) 40
sugar phosphates - metabolism (40) 40
terpenoids (36) 36
mep pathway (33) 33
plants (33) 33
crystal-structure (29) 29
higher-plants (29) 29
mevalonic acid - metabolism (29) 29
fosmidomycin (28) 28
research (28) 28
bacteria (27) 27
escherichia coli - genetics (27) 27
biophysics (26) 26
cloning, molecular (26) 26
enzyme (26) 26
cell biology (25) 25
1-deoxy-d-xylulose 5-phosphate synthase (24) 24
aldose-ketose isomerases - metabolism (24) 24
biotechnology & applied microbiology (24) 24
dimethylallyl diphosphate (24) 24
escherichia coli - enzymology (24) 24
protein (24) 24
escherichia coli (23) 23
escherichia coli - metabolism (23) 23
models, molecular (23) 23
oxidoreductases - metabolism (23) 23
catalysis (22) 22
erythritol - chemistry (22) 22
heterologous expression (22) 22
kinetics (22) 22
microbiology (22) 22
synthase (22) 22
cloning (21) 21
fosfomycin - analogs & derivatives (21) 21
mevalonate (21) 21
molecular structure (21) 21
organophosphorus compounds - metabolism (21) 21
analysis (20) 20
bacterial proteins - metabolism (20) 20
humans (20) 20
isoprenoid (20) 20
2-c-methyl-d-erythritol (19) 19
gene expression regulation, plant (19) 19
life sciences (19) 19
multienzyme complexes - metabolism (19) 19
genes (18) 18
genetic aspects (18) 18
hemiterpenes (18) 18
mevalonate pathway (18) 18
mycobacterium-tuberculosis (18) 18
phylogeny (18) 18
precursor (18) 18
animals (17) 17
arabidopsis-thaliana (17) 17
bacterial proteins - genetics (17) 17
fosfomycin - pharmacology (17) 17
sequence homology, amino acid (17) 17
1-deoxy-d-xylulose 5-phosphate (16) 16
2-c-methyl-d-erythritol 2,4-cyclodiphosphate (16) 16
aldose-ketose isomerases - chemistry (16) 16
biochemistry (16) 16
gcpe (16) 16
oxidoreductases - chemistry (16) 16
oxidoreductases - genetics (16) 16
pathway (16) 16
plant proteins - metabolism (16) 16
proteins (16) 16
chemistry, medicinal (15) 15
gene expression (15) 15
lytb (15) 15
metabolism (15) 15
reductoisomerase (15) 15
terpenes (15) 15
-4-hydroxy-3-methylbut-2-enyl diphosphate (14) 14
2c-methyl-d-erythritol 2,4-cyclodiphosphate (14) 14
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Journal Article
FEBS Letters, ISSN 0014-5793, 2005, Volume 579, Issue 17, pp. 3802 - 3806
Although flavodoxin I is indispensable for growth, the exact pathway(s) where flavodoxin I is essential has not been identified. We performed transposon... 
2- C-Methyl- D-erythritol 4-phosphate | ( E)-4-Hydroxy-3-methylbutyl-2-enyl pyrophosphate | Flavodoxin I | fldA | γδ T cell | PBS | isopentenyl pyrophosphate | dimethylallyl pyrophosphate | HMBPP | IPP | erythritol 4-phosphate | Luria-Bertani | mevalonate | 4-hydroxy-3-methylbutyl-2-enyl pyrophosphate | phosphate buffered saline | MEP | MVA | DMAPP | methyl | (E)-4-Hydroxy-3- methylbutyl-2-enyl pyrophosphate | 2-C-Methyl-D-erythritol 4-phosphate | ISPH PROTEIN | METHYLERYTHRITOL PHOSPHATE-PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | 4FE-4S PROTEIN | DELTA-T-CELLS | flavodoxin I | gamma delta T cell | CELL BIOLOGY | SP STRAIN CL190 | GCPE | BIOPHYSICS | (E)-4-hydroxy-3-methylbutyl-2-enyl pyrophosphate | ISOPENTENYL DIPHOSPHATE | MEVALONATE PATHWAY | 2-C-methyl-D-erythritol 4-phosphate | NONMEVALONATE PATHWAY | Glycine - genetics | Flavodoxin - metabolism | Erythritol - analogs & derivatives | Flavodoxin - genetics | Escherichia coli Proteins - physiology | Genes, Essential | Genetic Complementation Test | Aspartic Acid - genetics | Sugar Phosphates - metabolism | Terpenes - metabolism | Mutagenesis | Escherichia coli - genetics | Escherichia coli - metabolism | Escherichia coli Proteins - genetics | Erythritol - metabolism | Amino Acid Substitution | Phosphates | Enzymes | Transposons | Gene mutations | Escherichia coli | Genetic research | Physiological aspects | Universities and colleges | Index Medicus
Journal Article
Journal Article
Journal Article
FEBS Letters, ISSN 0014-5793, 2001, Volume 488, Issue 3, pp. 170 - 173
The 2‐ C ‐methyl‐ D ‐erythritol 4‐phosphate (MEP) pathway for isoprenoid biosynthesis is essential in most eubacteria and plants and has remarkable... 
GcpE | 2- C-methyl- D-erythritol 4-phosphate pathway | Mevalonic acid | Isoprenoid biosynthesis | xylulose 5-phosphate synthase | erythritol 4-phosphate pathway | DXR, 1-deoxy | erythritol 4-phosphate | ME-2,4cPP, 2 | MEP, 2 | xylulose 5-phosphate reductoisomerase | erythritol 2-phosphate | methyl | DMAPP, dimethylallyl diphosphate | MVA, mevalonate | ORF, open reading frame | CDP-ME2P, 4-diphosphocytidyl-2 | chloramphenicol acetyl transferase | IPP, isopentenyl diphosphate | DXS, 1-deoxy | DXP, 1-deoxy | CAT | xylulose 5-phosphate | erythritol 2,4-cyclodiphosphate | CDP-ME, 4-diphosphocytidyl-2 | erythritol | 2-C-methyl-D-erythritol 4-phosphate pathway | isoprenoid biosynthesis | PRECURSOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | TERPENOID BIOSYNTHESIS | THIAMIN | CELL BIOLOGY | GepE | BIOPHYSICS | CATALYZES | PYRIDOXOL | 5-PHOSPHATE | mevalonic acid | PLANTS | Enzymes | Erythritol - analogs & derivatives | Erythritol - chemistry | Genes, Bacterial - genetics | Sugar Phosphates - chemistry | Bacterial Proteins - chemistry | Bacterial Proteins - genetics | Escherichia coli - chemistry | Open Reading Frames - genetics | Genetic Complementation Test | Sequence Homology | Sugar Phosphates - metabolism | Escherichia coli - genetics | Gene Deletion | Cloning, Molecular | Escherichia coli - metabolism | Bacterial Proteins - metabolism | Erythritol - metabolism | Index Medicus
Journal Article
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 03/2001, Volume 166, Issue 6, pp. 3655 - 3658
Journal Article
Bioscience, Biotechnology, and Biochemistry, ISSN 0916-8451, 11/2008, Volume 72, Issue 11, pp. 2903 - 2917
Journal Article
Journal Article
FEBS LETTERS, ISSN 0014-5793, 12/2001, Volume 509, Issue 2, pp. 317 - 322
The gcpE and lytB gene products control the terminal steps of isoprenoid biosynthesis via the 2-C-methyl-D-erythritol 4-phosphate pathway in Escherichia coli.... 
4-hydroxy-3-methyl-but-2-enyl pyrophosphate | gcpE | 2-C-methyl-D-erythritol 4-phosphate pathway | 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE | BIOCHEMISTRY & MOLECULAR BIOLOGY | lytB | gamma delta T cell | CELL BIOLOGY | EVOLUTION | BIOPHYSICS | ISOPRENOID BIOSYNTHESIS | MEVALONATE-INDEPENDENT PATHWAY | NONMEVALONATE PATHWAY | LYMPHOCYTES | ANTIGEN
Journal Article
Journal Article
FEBS Letters, ISSN 0014-5793, 2003, Volume 541, Issue 1, pp. 115 - 120
The last enzyme (LytB) of the methylerythritol phosphate pathway for isoprenoid biosynthesis catalyzes the reduction of ( E )‐4‐hydroxy‐3‐methylbut‐2‐enyl... 
2- C-Methyl- D-erythritol 4-phosphate pathway | Isoprenoid | Isopentenyl diphosphate | ( E)-4-Hydroxy-3-methylbut-2-enyl diphosphate | Dimethylallyl diphosphate | LytB | EPR, electron paramagnetic resonance | HMBPP | erythritol 4-phosphate pathway | erythritol 4-phosphate | 4-Hydroxy-3-methylbut-2-enyl diphosphate | IPP, isopentenyl diphosphate | MEP, 2 | Methyl | DAF, 5-deazaflavin (10-methyl-5-deazaisoalloxazine) | DMAPP, dimethylallyl diphosphate | ME, 2 | erythritol | (E)-4-Hydroxy-3-methylbut-2-enyl diphosphate | 2-C-Methyl-D-erythritol 4-phosphate pathway | IRON-SULFUR PROTEINS | 2-C-methyl-D-erythritol 4-phosphate pathway | CONVERSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | QUANTITATION | LYASE ACTIVATING ENZYME | isopentenyl diphosphate | (E)-4-hydroxy-3-methylbut-2-enyl diphosphate | CELL BIOLOGY | SYNTHASE | BIOPHYSICS | CLUSTERS | HIGHER-PLANTS | 2-C-METHYL-D-ERYTHRITOL | PYROPHOSPHATE | dimethylallyl diphosphate | isoprenoid | NONMEVALONATE PATHWAY | Diphosphates - metabolism | Escherichia coli - enzymology | Electron Spin Resonance Spectroscopy | Erythritol - analogs & derivatives | Models, Chemical | Oxidoreductases - metabolism | Polyisoprenyl Phosphate Sugars - biosynthesis | Escherichia coli Proteins - metabolism | Iron-Sulfur Proteins - chemistry | Organophosphorus Compounds - metabolism | Oxidoreductases - chemistry | Sugar Phosphates - metabolism | Hemiterpenes | Erythritol - metabolism | Iron-Sulfur Proteins - metabolism | Escherichia coli Proteins - chemistry | NADH, NADPH Oxidoreductases - metabolism | isoprenoids | LytB protein | diphosphate reductase | methylerythritol phosphate | Index Medicus
Journal Article