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Original Article - Enhancement of radionuclide induced cytotoxicity by 2-deoxy-D-glucose in human tumor cell lines, 12/2006
The efficacy of targeted radiotherapy can be enhanced by selective delivery of radionuclide to the tumors and/or by differentially enhancing the manifestation... 
Radionuclide, micronuclei frequency, 2-deoxy-D-Glucose, survival
Journal
Journal of Neurophysiology, ISSN 0022-3077, 05/2018, Volume 119, Issue 5, pp. 1912 - 1923
The ketogenic diet (KD), a high-fat, carbohydrate-restricted diet, is used as an alternative treatment for drug-resistant epileptic patients. Evidence suggests... 
Glycolysis | 2-deoxy-D-glucose | Oxidative phosphorylation | Epileptiform activity | In vitro
Journal Article
Cancer Research, ISSN 0008-5472, 01/2019, Volume 79, Issue 2, pp. 331 - 345
Tumor cells exhibiting the Warburg effect rely on aerobic glycolysis for ATP production and have a notable addiction to anaplerotic use of glutamine for... 
HERPES-SIMPLEX-VIRUS | ACTIVATION | METABOLISM | ONCOLOGY | GLUCOSE | BIOLOGY | 2-DEOXY-D-GLUCOSE | NUTRITIONAL REQUIREMENTS | INDUCTION
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 01/2019, Volume 25, Issue 2, pp. 844 - 855
Purpose: Hexokinase II (HK2) protein expression is elevated in glioblastoma (GBM), and we have shown that HK2 could serve as an effective therapeutic target... 
SURVIVAL | AGENT | INHIBITION | GENE | ONCOLOGY | II HEXOKINASE | 2-DEOXY-D-GLUCOSE | 3-BROMOPYRUVATE | DIFFERENTIATION | CANCER | BRAIN
Journal Article
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, ISSN 0735-1097, 08/2011, Volume 58, Issue 6, pp. 603 - 614
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 09/2018, Volume 201, Issue 5, pp. 1400 - 1411
Glucose-derived mannose is a common component of glycoproteins, and its deficiency leads to a severe defect in protein glycosylation and failure in basic cell... 
IN-VITRO | INHIBITION | 2-DEOXYGLUCOSE | GLUCOSE | AEROBIC GLYCOLYSIS | GLYCOPROTEINS | TUMOR-CELLS | 2-DEOXY-D-GLUCOSE | GLYCOSYLATION | IMMUNOLOGY | LIPID-LINKED OLIGOSACCHARIDES
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 8919 - 13
Insulin-like growth factor-1 (IGF-1) is synthesised as a prohormone (proIGF-1) requiring enzymatic activity to yield the mature IGF-1. Three proIGF-1s are... 
INHIBITION | MULTIDISCIPLINARY SCIENCES | COMPLEXITY | GLYCANS | MUSCLE | ENDOPLASMIC-RETICULUM | 2-DEOXY-D-GLUCOSE | PROTEINS | EXPRESSION | CELL-DEATH
Journal Article
Iranian Journal of Medical Sciences, ISSN 0253-0716, 03/2019, Volume 44, Issue 2, pp. 99 - 107
Both mitochondrial dysfunction and aerobic glycolysis are signs of growing aggressive cancer. If altered metabolism of cancer cell is intended, using the... 
Esophageal carcinoma | Metformin | 2-Deoxy-D-Glucose | Apoptosis | Original | apoptosis
Journal Article
International Journal of Toxicology, ISSN 1091-5818, 2016, Volume 35, Issue 3, pp. 284 - 293
Journal Article
Journal Article
by Zhao, SG and Liu, HL and Liu, YH and Wu, JN and Wang, CL and Hou, X and Chen, XF and Yang, G and Zhao, L and Che, H and Bi, YK and Wang, HY and Peng, F and Ai, J
CANCER LETTERS, ISSN 0304-3835, 06/2013, Volume 333, Issue 2, pp. 253 - 260
Glioblastomas rely mainly on aerobic glycolysis to sustain proliferation and growth; however, little is known about the regulatory mechanisms of metabolism in... 
GLIOMA-CELLS | HEXOKINASE 2 | Glioblastoma stem-like cells | Neurosphere | 2-Deoxy-D-glucose (2-DG) | 2-DEOXY-D-GLUCOSE | HYPOXIA | SUPPRESSION | BREAST-CANCER CELLS | ONCOLOGY | miR-143 | GROWTH | Glycolysis | CHEMORESISTANCE | DIFFERENTIATION | EXPRESSION
Journal Article
Cancer Investigation, ISSN 0735-7907, 02/2018, Volume 36, Issue 2, pp. 93 - 105
Primary malignant glioma cell lines are being used for initial screening of anticancer agents. We utilized a simple mechanical disaggregation method for... 
Malignant gliomas | Radiation therapy | Temozolomide | 2-deoxy-d-glucose | Primary cell lines
Journal Article
PLOS PATHOGENS, ISSN 1553-7366, 01/2019, Volume 15, Issue 1
Human Cytomegalovirus (HCMV) infection induces several metabolic activities that are essential for viral replication. Despite the important role that this... 
MAMMALIAN TARGET | COMPLEX | ACTIVATION | FATTY-ACID SYNTHESIS | MICROBIOLOGY | 2-DEOXY-D-GLUCOSE | VIRAL REPLICATION | CELL-DEATH | VIROLOGY | INFECTION | STRESS | EXPRESSION | PARASITOLOGY
Journal Article
The American Journal of Pathology, ISSN 0002-9440, 01/2018, Volume 188, Issue 1, pp. 72 - 83
Tumor immune microenvironment and tumor metabolism are major determinants of chemoradiotherapy response. The interdependency and prognostic significance of... 
TUMOR-INFILTRATING LYMPHOCYTES | BREAST-CANCER | OXIDATIVE STRESS | RECTAL-CANCER | GLUCOSE-TRANSPORTER-1 | LACTATE | HYDROGEN-PEROXIDE | 2-DEOXY-D-GLUCOSE | PATHOLOGY | RADIATION | CD8(+) T-CELLS
Journal Article
PLOS ONE, ISSN 1932-6203, 11/2017, Volume 12, Issue 11
A glucose analog called 2-deoxy-D-glucose (2DG) has been successfully used to sensitize cancer cells to ROS-inducing cancer treatments such as ionizing... 
CANCER-CELLS | DOSE-ESCALATION | OXIDATIVE STRESS | METABOLISM | 2-DEOXYGLUCOSE | EFFICACY | MULTIDISCIPLINARY SCIENCES | HIGH AEROBIC GLYCOLYSIS | ADRIAMYCIN | 2-DEOXY-D-GLUCOSE | ANTITUMOR-ACTIVITY
Journal Article
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