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index medicus (353) 353
20-hydroxysteroid dehydrogenases - metabolism (278) 278
animals (207) 207
female (187) 187
humans (169) 169
20-hydroxysteroid dehydrogenases - genetics (104) 104
rats (102) 102
20-alpha-hydroxysteroid dehydrogenase (92) 92
kinetics (79) 79
3-hydroxysteroid dehydrogenases - metabolism (70) 70
pregnancy (66) 66
progesterone - metabolism (61) 61
male (56) 56
mice (53) 53
biochemistry & molecular biology (48) 48
endocrinology & metabolism (47) 47
20-hydroxysteroid dehydrogenases - antagonists & inhibitors (46) 46
cells, cultured (45) 45
progesterone (43) 43
substrate specificity (39) 39
expression (34) 34
pharmacology & pharmacy (32) 32
aldo-keto reductase family 1 member c3 (31) 31
abridged index medicus (30) 30
hydroxysteroid dehydrogenases - metabolism (30) 30
ovary - enzymology (30) 30
17-hydroxysteroid dehydrogenases - metabolism (29) 29
aldo-keto reductase (29) 29
corpus luteum - enzymology (29) 29
hydroxyprostaglandin dehydrogenases - metabolism (29) 29
20-hydroxysteroid dehydrogenases - chemistry (28) 28
gene expression (28) 28
rats, inbred strains (27) 27
3-hydroxysteroid dehydrogenases - genetics (25) 25
binding sites (25) 25
cell line, tumor (25) 25
molecular sequence data (25) 25
physiological aspects (25) 25
placenta - enzymology (25) 25
amino acid sequence (24) 24
20-hydroxysteroid dehydrogenases - isolation & purification (23) 23
enzymes (23) 23
hydroxysteroid dehydrogenases - genetics (23) 23
3-alpha-hydroxysteroid dehydrogenase (22) 22
aldo-keto reductases (22) 22
metabolism (22) 22
rna, messenger - metabolism (22) 22
20-hydroxysteroid dehydrogenases - biosynthesis (21) 21
progesterone - biosynthesis (21) 21
cell line (20) 20
cloning, molecular (20) 20
progesterone - blood (20) 20
cancer (19) 19
hydroxyprostaglandin dehydrogenases - genetics (19) 19
oxidoreductases - metabolism (19) 19
toxicology (19) 19
alcohol oxidoreductases - metabolism (18) 18
cortisone reductase - metabolism (18) 18
rats, wistar (18) 18
reverse transcriptase polymerase chain reaction (18) 18
cell biology (17) 17
dihydrodiol dehydrogenase (17) 17
in vitro techniques (17) 17
models, molecular (17) 17
nadp - metabolism (17) 17
ovary - metabolism (17) 17
protein binding (17) 17
rna, messenger - genetics (17) 17
adult (16) 16
base sequence (16) 16
corpus luteum - metabolism (16) 16
gene expression regulation, enzymologic (16) 16
oxidation-reduction (16) 16
purification (16) 16
recombinant proteins - metabolism (16) 16
tissue distribution (16) 16
cattle (15) 15
corpus luteum - drug effects (15) 15
cytosol - enzymology (15) 15
enzyme inhibitors - pharmacology (15) 15
gene-expression (15) 15
granulosa cells - metabolism (15) 15
interleukin-3 (15) 15
isoenzymes - metabolism (15) 15
keto reductase superfamily (15) 15
middle aged (15) 15
oncology (15) 15
testis - enzymology (15) 15
transfection (15) 15
cells (14) 14
chemistry, medicinal (14) 14
genes (14) 14
granulosa cells - drug effects (14) 14
hydroxysteroid dehydrogenases (14) 14
ovary - drug effects (14) 14
rats, sprague-dawley (14) 14
reproductive biology (14) 14
dose-response relationship, drug (13) 13
follicle stimulating hormone - pharmacology (13) 13
gestational age (13) 13
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Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 12/2010, Volume 335, Issue 3, pp. 533 - 545
Doxorubicin (DOX) and daunorubicin (DAUN) are effective anticancer drugs; however, considerable interpatient variability exists in their pharmacokinetics. This... 
DIHYDRODIOL DEHYDROGENASE ISOFORMS | QUINONE REDUCTASE | HUMAN CARBONYL REDUCTASE | ENZYMES | ANTHRACYCLINE-INDUCED CARDIOTOXICITY | SUPERFAMILY | PHARMACOLOGY & PHARMACY | HUMAN LIVER | ALDEHYDE REDUCTASE | SINGLE NUCLEOTIDE POLYMORPHISMS | PROSTAGLANDIN-F SYNTHASE | Aldehyde Reductase - genetics | Humans | Polymorphism, Single Nucleotide - physiology | Mitochondrial Proteins - genetics | NAD(P)H Dehydrogenase (Quinone) - genetics | Hydroxyprostaglandin Dehydrogenases - metabolism | Alcohol Oxidoreductases - genetics | Recombinant Proteins - isolation & purification | Mitochondrial Proteins - metabolism | 3-Hydroxysteroid Dehydrogenases - metabolism | Aldehyde Reductase - metabolism | Hydroxysteroid Dehydrogenases - metabolism | Doxorubicin - metabolism | Daunorubicin - metabolism | Glyceraldehyde - metabolism | Phenanthrenes - metabolism | Recombinant Proteins - metabolism | 20-Hydroxysteroid Dehydrogenases - genetics | Biocatalysis | Oxidoreductases - metabolism | Oxidoreductases - genetics | Gene Frequency | Indans - metabolism | Models, Molecular | Alcohol Oxidoreductases - metabolism | Recombinant Proteins - genetics | Hydroxysteroid Dehydrogenases - genetics | 20-Hydroxysteroid Dehydrogenases - metabolism | Hydroxyprostaglandin Dehydrogenases - genetics | Aldo-Keto Reductases | Vitamin K 3 - metabolism | Aldo-Keto Reductase Family 1 Member C3 | NAD(P)H Dehydrogenase (Quinone) - metabolism | Kinetics | 3-Hydroxysteroid Dehydrogenases - genetics | Index Medicus
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 06/2008, Volume 93, Issue 6, pp. 2366 - 2374
Context: Experimental and clinical studies in a variety of nonprimate species demonstrate that progesterone withdrawal leads to changes in gene expression that... 
17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE-2 | UTERINE CERVIX | ENDOCRINOLOGY & METABOLISM | PRETERM BIRTH | 5-ALPHA-REDUCTASE TYPE-1 | DEHYDROGENASE-ACTIVITY | HUMAN-ENDOMETRIUM | GUINEA-PIG | RECEPTOR-A | EXPRESSION | INTERLEUKIN-8 PRODUCTION | Cervical Ripening - metabolism | Cervix Uteri - metabolism | Humans | RNA, Messenger - metabolism | Hydroxyprostaglandin Dehydrogenases - metabolism | Myometrium - metabolism | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - metabolism | 3-Hydroxysteroid Dehydrogenases - metabolism | Female | Hydroxysteroid Dehydrogenases - metabolism | Estrogens - metabolism | 20-Hydroxysteroid Dehydrogenases - genetics | Oxidoreductases - metabolism | Oxidoreductases - genetics | Cervix Uteri - enzymology | Parturition - genetics | Hydroxysteroid Dehydrogenases - genetics | 20-Hydroxysteroid Dehydrogenases - metabolism | Gestational Age | Hydroxyprostaglandin Dehydrogenases - genetics | Gene Expression Regulation, Enzymologic | Pregnancy | Animals | Aldo-Keto Reductase Family 1 Member C3 | Estradiol Dehydrogenases | Models, Biological | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - genetics | Cervix Uteri - physiology | Progesterone - metabolism | Mice | 3-Hydroxysteroid Dehydrogenases - genetics | 17-Hydroxysteroid Dehydrogenases - metabolism | Parturition - metabolism | Index Medicus | Abridged Index Medicus | Original
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 2006, Volume 248, Issue 1, pp. 126 - 135
Endometrial cancer is the most common malignancy of the female genital tract. Its incidence correlates with prolonged estrogen stimulation unopposed by... 
Short-chain dehydrogenase reductase | 17β-Hydroxysteroid dehydrogenase | 20α-Hydroxysteroid dehydrogenase | Aldo-keto reductase | 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE-2 | HYDROXYSTEROID DEHYDROGENASES | ER-BETA | short-chain dehydrogenase reductase | RECEPTOR-B | CELL BIOLOGY | INACTIVATION | CARCINOGENESIS | KETO REDUCTASE SUPERFAMILY | ENDOCRINOLOGY & METABOLISM | 20 alpha-hydroxysteroid dehydrogenase | aldo-keto reductase | 17 beta-hydroxysteroid dehydrogenase | EXPRESSION | CARCINOMA | HORMONES | Humans | Endometrial Neoplasms - metabolism | Hydroxyprostaglandin Dehydrogenases - metabolism | Estrogens - analysis | Endometrial Neoplasms - genetics | Isoenzymes - metabolism | 3-Hydroxysteroid Dehydrogenases - metabolism | Female | Progesterone - biosynthesis | Tumor Cells, Cultured | Estradiol - biosynthesis | Endometrium - metabolism | Progesterone - analysis | 20-Hydroxysteroid Dehydrogenases - genetics | Estrogens - biosynthesis | Endometrial Neoplasms - chemistry | Oxidoreductases - metabolism | Isoenzymes - genetics | 20-Hydroxysteroid Dehydrogenases - metabolism | Hydroxyprostaglandin Dehydrogenases - genetics | Endometrium - chemistry | Animals | Aldo-Keto Reductase Family 1 Member C3 | Estradiol Dehydrogenases | 3-Hydroxysteroid Dehydrogenases - genetics | 17-Hydroxysteroid Dehydrogenases - metabolism | Enzymes | Care and treatment | Endometrial cancer | Phenols | Hormones | Progesterone | Estradiol | Cancer | Index Medicus
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 02/2013, Volume 202, Issue 1-3, pp. 210 - 217
► In endometrial cancer progesterone biosynthesis genes are down-regulated. ► Expression of most progesterone metabolism genes is not altered in cancerous... 
Steroidogenic acute regulatory protein | 5α-Reductase | Pre-receptor metabolism | Side-chain cleavage enzyme | 3-Keto/20-keto-reductase | 3-ALPHA-HYDROXYSTEROID DEHYDROGENASES | ADENOCARCINOMA | BIOCHEMISTRY & MOLECULAR BIOLOGY | STEROID 5-ALPHA-REDUCTASE | RECEPTOR-A | 5 alpha-Reductase | ER-ALPHA | 17-BETA-HYDROXYSTEROID-DEHYDROGENASE | KETO REDUCTASE SUPERFAMILY | ESTROGEN | PHARMACOLOGY & PHARMACY | TOXICOLOGY | YOUNG-WOMEN | TYPE-2 | Cholesterol Side-Chain Cleavage Enzyme - metabolism | Progesterone Reductase - metabolism | Humans | Middle Aged | Endometrial Neoplasms - metabolism | Multienzyme Complexes - metabolism | Receptors, Progesterone - genetics | Hydroxyprostaglandin Dehydrogenases - metabolism | Receptors, Progesterone - metabolism | Cholesterol Side-Chain Cleavage Enzyme - genetics | Endometrial Neoplasms - genetics | Phosphoproteins | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - metabolism | Aged, 80 and over | 3-Hydroxysteroid Dehydrogenases - metabolism | Adult | Female | Progesterone - biosynthesis | Membrane Proteins - metabolism | Steroid Isomerases - genetics | Endometrium - metabolism | 20-Hydroxysteroid Dehydrogenases - genetics | Membrane Proteins - genetics | Steroid Isomerases - metabolism | RNA, Messenger - genetics | Multienzyme Complexes - genetics | Progesterone Reductase - genetics | 20-Hydroxysteroid Dehydrogenases - metabolism | Down-Regulation - genetics | Hydroxyprostaglandin Dehydrogenases - genetics | Aldo-Keto Reductase Family 1 Member C3 | Estradiol Dehydrogenases - genetics | 17-Hydroxysteroid Dehydrogenases - genetics | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - genetics | Estradiol Dehydrogenases - metabolism | Progesterone - metabolism | Aged | Progesterone - genetics | 3-Hydroxysteroid Dehydrogenases - genetics | 17-Hydroxysteroid Dehydrogenases - metabolism | Endometrial cancer | RNA | Genes | Cytochrome P-450 | Physiological aspects | Genetic aspects | Progesterone | Cancer | Index Medicus
Journal Article
Journal Article
Biochemical Journal, ISSN 0264-6021, 07/2011, Volume 437, Issue 1, pp. 53 - 61
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 03/2012, Volume 55, Issue 5, pp. 2311 - 2323
Aldo-keto reductase 1C3 (AKR1C3; type 5 17 beta-hydroxysteroid dehydrogenase) is overexpressed in castration resistant prostate cancer (CRPC) and is implicated... 
TARGET | CHEMISTRY, MEDICINAL | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | PURIFICATION | BIOLOGICAL EVALUATION | AKR1C3 | ABIRATERONE ACETATE | 17-BETA-HSD1 | RESISTANT PROSTATE-CANCER | EXPRESSION | 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE | Antineoplastic Agents - chemical synthesis | Humans | Male | Structure-Activity Relationship | Hydroxyprostaglandin Dehydrogenases - metabolism | Fenamates - pharmacology | 3-Hydroxysteroid Dehydrogenases - antagonists & inhibitors | 20-Hydroxysteroid Dehydrogenases - antagonists & inhibitors | 3-Hydroxysteroid Dehydrogenases - metabolism | Antineoplastic Agents - pharmacology | Prostatic Neoplasms - drug therapy | Fenamates - chemistry | Testosterone - biosynthesis | Cyclooxygenase Inhibitors - chemistry | Antineoplastic Agents - chemistry | Hydroxyprostaglandin Dehydrogenases - genetics | Cyclooxygenase Inhibitors - pharmacology | Hydroxyprostaglandin Dehydrogenases - antagonists & inhibitors | Aldo-Keto Reductase Family 1 Member C3 | Testosterone - antagonists & inhibitors | Cyclooxygenase 2 - metabolism | Cyclooxygenase Inhibitors - chemical synthesis | Cell Line, Tumor | Hydroxysteroid Dehydrogenases - antagonists & inhibitors | Fenamates - chemical synthesis | Cyclooxygenase 1 - metabolism | 3-Hydroxysteroid Dehydrogenases - genetics | Isoenzymes - antagonists & inhibitors | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2014, Volume 9, Issue 5, pp. e97448 - e97448
G1-phase cell cycle defects, such as alterations in cyclin D1 or cyclin-dependent kinase (cdk) levels, are seen in most tumors. For example, increased cyclin... 
CDK6 | ETS2 TRANSCRIPTION FACTOR | DEHYDROGENASE ISOFORMS | MULTIDISCIPLINARY SCIENCES | ALDO-KETO REDUCTASES | MAST-CELLS | REVEALS ROLES | RECEPTOR | PROLIFERATION | STEROID-HORMONE | G PHASE | Cyclin D1 - metabolism | Cytochrome P-450 CYP1B1 - genetics | Cell Proliferation | Cyclin-Dependent Kinase 4 - genetics | Humans | Gene Expression Regulation, Neoplastic | Aromatase - metabolism | Cytochrome P-450 CYP1B1 - metabolism | Mammary Glands, Human - metabolism | Hydroxyprostaglandin Dehydrogenases - metabolism | Aromatase - genetics | 3-Hydroxysteroid Dehydrogenases - metabolism | Female | Hydroxysteroid Dehydrogenases - metabolism | G1 Phase - genetics | Estrogens - metabolism | Estradiol - metabolism | 20-Hydroxysteroid Dehydrogenases - genetics | Signal Transduction | Cyclin-Dependent Kinase 6 - genetics | Mammary Glands, Human - pathology | Cyclin-Dependent Kinase 6 - metabolism | Hydroxysteroid Dehydrogenases - genetics | 20-Hydroxysteroid Dehydrogenases - metabolism | Cyclin-Dependent Kinase 4 - metabolism | Hydroxyprostaglandin Dehydrogenases - genetics | Cyclin D1 - genetics | Aldo-Keto Reductase Family 1 Member C3 | Estradiol Dehydrogenases - genetics | Estrone - metabolism | Estradiol Dehydrogenases - metabolism | Cell Line, Tumor | 3-Hydroxysteroid Dehydrogenases - genetics | Genes | Estrogen | Cytochrome P-450 | Physiological aspects | Phenols | Breast cancer | Small and medium sized companies | Phosphotransferases | Cytochrome | Cell proliferation | Cell culture | Pediatrics | Phosphorylation | Transcription | Estrogens | Homology | Biology | Kinases | Cyclin D1 | Experiments | Estradiol | Cyclin-dependent kinase 4 | Proteins | Cyclin-dependent kinase | Alterations | Cell growth | Xenoestrogens | Rodents | Aromatase | Cell cycle | Enzymes | Tumor cells | Cyclin-dependent kinases | Cytochrome P450 | Tumor cell lines | Metabolism | Gene expression | Aldo-keto reductase | Sex hormones | Gene amplification | Breast | Estrone | Tumors | Cancer | Index Medicus
Journal Article
BMC Cancer, ISSN 1471-2407, 08/2012, Volume 12, Issue 1, pp. 381 - 381
Background: Since proteins involved in chemotherapy drug pharmacokinetics and pharmacodynamics have a strong impact on the uptake, metabolism, and efflux of... 
Resistance | Lysosome | Cytotoxicity | Drug localization | Aldo-keto reductases | Pharmacokinetics | Doxorubicin | DNA-binding | Gene profiling | PharmGKB | BIOLOGICAL PATHWAYS | MINIMUM INFORMATION | CARBONYL REDUCTASE | CELL-LINES | BREAST-CANCER | DRUG TRANSPORTERS | ONCOLOGY | HUMAN LIVER | MULTIDRUG-RESISTANCE | ANTHRACYCLINES | MICROARRAY DATA | 3-Hydroxysteroid Dehydrogenases - biosynthesis | Aldehyde Reductase - genetics | Oligonucleotide Array Sequence Analysis | Cyclosporine - pharmacology | DNA, Neoplasm - metabolism | Humans | Drug Resistance, Neoplasm | Gene Expression Profiling | Hydroxyprostaglandin Dehydrogenases - metabolism | Breast Neoplasms - metabolism | Cell Nucleus - metabolism | MCF-7 Cells | Doxorubicin - analogs & derivatives | 3-Hydroxysteroid Dehydrogenases - metabolism | Aldehyde Reductase - metabolism | 20-Hydroxysteroid Dehydrogenases - biosynthesis | 20-Hydroxysteroid Dehydrogenases - genetics | Intracellular Space - drug effects | Aldehyde Reductase - biosynthesis | Hydroxyprostaglandin Dehydrogenases - biosynthesis | 20-Hydroxysteroid Dehydrogenases - metabolism | Breast Neoplasms - drug therapy | Doxorubicin - pharmacokinetics | Hydroxyprostaglandin Dehydrogenases - genetics | Cholic Acids - pharmacology | Breast Neoplasms - genetics | Aldo-Keto Reductase Family 1 Member C3 | Intracellular Space - metabolism | 3-Hydroxysteroid Dehydrogenases - genetics | Cell Nucleus - drug effects | Doxorubicin - pharmacology | Aldose reductase | Physiological aspects | Research | Drug resistance | DNA-ligand interactions | Anthracyclines | Genes | Genomics | Genomes | Proteins | Chemotherapy | Metabolites | Analysis | DNA | Genetic research | Cancer | Index Medicus
Journal Article
Biochemical Journal, ISSN 0264-6021, 12/2011, Volume 440, Issue 3, pp. 335 - 344
Human AKR (aldo-keto reductase) 1C proteins (AKR1C1-AKR1C4) exhibit relevant activity with steroids, regulating hormone signalling at the pre-receptor level.... 
Aldo-keto reductase (AKR) | Retinaldehyde | Proliferation | Retinoic acid | Retinol | 3-ALPHA-HYDROXYSTEROID DEHYDROGENASES | proliferation | BIOCHEMISTRY & MOLECULAR BIOLOGY | aldo-keto reductase (AKR) | retinaldehyde | STEROID-HORMONE | DIHYDRODIOL DEHYDROGENASE | retinol | SHORT-CHAIN DEHYDROGENASES/REDUCTASES | BREAST-CANCER CELLS | retinoic acid | METABOLISM | REVEALS ROLES | MCF-7 CELLS | PROSTAGLANDIN-F SYNTHASE | Vitamin A - pharmacology | Vitamin A - chemistry | Cell Proliferation | Hydroxysteroid Dehydrogenases - chemistry | Humans | Transcriptional Activation | 20-Hydroxysteroid Dehydrogenases - chemistry | Retinaldehyde - chemistry | Substrate Specificity | Hydroxyprostaglandin Dehydrogenases - metabolism | Oxidoreductases - chemistry | 3-Hydroxysteroid Dehydrogenases - metabolism | Hydroxysteroid Dehydrogenases - metabolism | Retinaldehyde - physiology | Hydroxyprostaglandin Dehydrogenases - chemistry | Binding Sites | Mutagenesis, Site-Directed | Oxidoreductases - metabolism | Models, Molecular | Receptors, Retinoic Acid - antagonists & inhibitors | Receptors, Retinoic Acid - metabolism | 20-Hydroxysteroid Dehydrogenases - metabolism | Hydroxyprostaglandin Dehydrogenases - genetics | Aldo-Keto Reductase Family 1 Member C3 | Vitamin A - physiology | Retinaldehyde - pharmacology | Cell Line, Tumor | Protein Binding | 3-Hydroxysteroid Dehydrogenases - chemistry | Kinetics | 3-Hydroxysteroid Dehydrogenases - genetics | Amino Acid Substitution | Index Medicus
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 02/2013, Volume 202, Issue 1-3, pp. 218 - 225
► Genes encoding P4 metabolizing enzymes are expressed in Z-12 endometriotic cells. ► Treatments with progesterone and dydrogesterone decrease expression. ►... 
Dydrogesterone | Peritoneal endometriosis | Medroxyprogesterone acetate | Pre-receptor metabolism | Progesterone resistance | Dienogest | 3-Hydroxysteroid Dehydrogenases - biosynthesis | Epithelial Cells - metabolism | Endometriosis - genetics | Epithelial Cells - drug effects | Humans | Endometrium - drug effects | Medroxyprogesterone Acetate - pharmacology | Receptors, Progesterone - genetics | Hydroxyprostaglandin Dehydrogenases - metabolism | Receptors, Progesterone - metabolism | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - metabolism | 3-Hydroxysteroid Dehydrogenases - metabolism | Female | Hydroxysteroid Dehydrogenases - biosynthesis | Hydroxysteroid Dehydrogenases - metabolism | Membrane Proteins - metabolism | Progesterone - pharmacology | Endometrium - metabolism | 20-Hydroxysteroid Dehydrogenases - genetics | Membrane Proteins - genetics | RNA, Messenger - genetics | Cells, Cultured | Nandrolone - analogs & derivatives | Progestins - pharmacology | Hydroxyprostaglandin Dehydrogenases - biosynthesis | Hydroxysteroid Dehydrogenases - genetics | 20-Hydroxysteroid Dehydrogenases - metabolism | Down-Regulation - drug effects | Down-Regulation - genetics | Hydroxyprostaglandin Dehydrogenases - genetics | Membrane Proteins - biosynthesis | Aldo-Keto Reductase Family 1 Member C3 | Estradiol Dehydrogenases - genetics | Nandrolone - pharmacology | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - genetics | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - biosynthesis | Dydrogesterone - pharmacology | Endometriosis - metabolism | Estradiol Dehydrogenases - metabolism | 3-Hydroxysteroid Dehydrogenases - genetics | Receptors, Progesterone - biosynthesis | Medroxyprogesterone | Physiological aspects | Progesterone | RNA | Index Medicus
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 2011, Volume 191, Issue 1, pp. 217 - 226
Endometriosis is a very common disease that is characterized by increased formation of estradiol and disturbed progesterone action. This latter is usually... 
5α-Reductase (SRD5A) | 5α-Dihydroprogesterone | Progesterone receptor B (PR-B) | 20α-Hydroxyprogesterone | 5β-Reductase (AKR1D1) | 5 alpha-Reductase (SRD5A) | BIOCHEMISTRY & MOLECULAR BIOLOGY | 5 beta-Reductase (AKR1D1) | PELVIC ENDOMETRIOSIS | 5 alpha-Dihydroprogesterone | RECEPTOR | DEHYDROGENASE-ACTIVITY | STEROID 5-BETA-REDUCTASE AKR1D1 | 5-ALPHA-REDUCTASE | BREAST-CANCER CELLS | 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE-2 EXPRESSION | REVEALS ROLES | ESTROGEN | PHARMACOLOGY & PHARMACY | TOXICOLOGY | 20 alpha-Hydroxyprogesterone | B PR-B | Up-Regulation | Endometriosis - genetics | Humans | RNA, Messenger - metabolism | Hydroxyprostaglandin Dehydrogenases - metabolism | Receptors, Progesterone - metabolism | 3-Hydroxysteroid Dehydrogenases - metabolism | Adult | Female | Hydroxysteroid Dehydrogenases - metabolism | 20-Hydroxysteroid Dehydrogenases - genetics | Membrane Proteins - genetics | Down-Regulation | RNA, Messenger - genetics | Endometriosis - pathology | Hydroxysteroid Dehydrogenases - genetics | 20-Hydroxysteroid Dehydrogenases - metabolism | Hydroxyprostaglandin Dehydrogenases - genetics | Gene Expression Regulation, Enzymologic | Aldo-Keto Reductase Family 1 Member C3 | Estradiol Dehydrogenases - genetics | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - genetics | Endometriosis - metabolism | Progesterone - metabolism | 3-Hydroxysteroid Dehydrogenases - genetics | Immunohistochemistry | Messenger RNA | Isoenzymes | Analysis | Physiological aspects | Endometriosis | Oxidoreductases | Progesterone | Index Medicus
Journal Article
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 02/2013, Volume 202, Issue 1-3, pp. 234 - 242
► Aldo–keto reductases 1C1 and 1C3 are evoked with colon cancer tolerance to cisplatin. ► A possible mechanism of the resistance is to detoxify toxic nonenals... 
Colon cancer cells | Aldo–keto reductase | Drug resistance | Cisplatin | Proteasome | Aldo-keto reductase | CARCINOMA-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY |