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Frontiers in Pharmacology, ISSN 1663-9812, 2015, Volume 6, p. 60
EBI2, aka GPR183, is a G-couple receptor originally identified in 1993 as one of main genes induced in Burkitt's lymphoma cell line BL41 by Epstein-Barr virus... 
25-OHC | EBI2
Journal Article
Neuropharmacology, ISSN 0028-3908, 05/2018, Volume 133, pp. 121 - 128
Journal Article
Journal of Crohn's and Colitis, ISSN 1873-9946, 02/2019, Volume 13, Issue 2, pp. 218 - 229
Abstract Background and Aims Inflammatory bowel diseases [IBD] represent a challenging health issue with a complex aetiology involving genetic and... 
Cyp3A | 25-OHC | LXR | 4β-OHC | ACTIVATION | CHOLESTEROL | MOUSE MODELS | LXR-ALPHA | CELL-MIGRATION | LIVER | GENE-EXPRESSION | 4 beta-OHC | GASTROENTEROLOGY & HEPATOLOGY | INFLAMMATORY BOWEL DISEASES | CONTRIBUTES | 25-HYDROXYCHOLESTEROL
Journal Article
by Sun, SQ and Liu, CL
FRONTIERS IN PHARMACOLOGY, ISSN 1663-9812, 03/2015, Volume 6
EBI2, aka GPR183, is a G-couple receptor originally identified in 1993 as one of main genes induced in Burkitt's lymphoma cell line BL41 by Epstein-Barr virus... 
SYSTEM | HOMEOSTASIS | EBI2 | RECEPTOR EBI2 | IDENTIFICATION | 7 alpha | 25-OHC | CLONING | PHARMACOLOGY & PHARMACY | OXYSTEROL-BINDING | LIGAND | B-CELL MIGRATION | EXPRESSION
Journal Article
Redox Biology, ISSN 2213-2317, 06/2018, Volume 16, pp. 139 - 145
Oxysterols (OHC) are biologically active cholesterol metabolites circulating in plasma that may be formed enzymatically (e.g. 24S-OHC, 25-OHC and 27-OHC) or by... 
Vascular disease | Hydroxycholesterol | Statin | Mass spectrometry | Dementia | VASCULAR RISK-FACTORS | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ATHEROSCLEROSIS | CHOLESTEROL PRECURSORS | STATINS | MASS-SPECTROMETRY | PLASMA | 24S-HYDROXYCHOLESTEROL | LDL-LIPIDS
Journal Article
EBioMedicine, ISSN 2352-3964, 02/2017, Volume 16, Issue C, pp. 238 - 250
While angiotensin II (ang II) has been implicated in the pathogenesis of cardiac cachexia (CC), the molecules that mediate ang II's wasting effect have not... 
Heart failure | Ch25h | TNF-α | Angiotensin II | Cardiac cachexia | TNF | MEDICINE, RESEARCH & EXPERIMENTAL | CHRONIC HEART-FAILURE | CANCER CACHEXIA | TNF-alpha | NECROSIS-FACTOR-ALPHA | GLYCOGEN-SYNTHASE KINASE-3-BETA | SKELETAL-MUSCLE | MYOGENIC DIFFERENTIATION | OXYSTEROL-INDUCED APOPTOSIS | EXERCISE INTOLERANCE | ISCHEMIA-REPERFUSION | GROWTH-FACTOR-I | Tumor Necrosis Factor-alpha - metabolism | Steroid Hydroxylases - metabolism | SKP Cullin F-Box Protein Ligases - genetics | Tumor Necrosis Factor-alpha - genetics | Male | Muscle, Skeletal - metabolism | Insulin-Like Growth Factor I - genetics | Muscular Atrophy - chemically induced | Receptors, Tumor Necrosis Factor, Type I - metabolism | Proto-Oncogene Proteins c-akt - genetics | Myoblasts - metabolism | Muscle, Skeletal - drug effects | Muscle Proteins - metabolism | Myoblasts - cytology | Muscular Atrophy - prevention & control | Proto-Oncogene Proteins c-akt - metabolism | Steroid Hydroxylases - genetics | Thiadiazoles - pharmacology | Cell Line | Muscular Atrophy - metabolism | Signal Transduction | Mice, Inbred C57BL | Cells, Cultured | Gene Expression Profiling - methods | Glycogen Synthase Kinase 3 beta - antagonists & inhibitors | SKP Cullin F-Box Protein Ligases - metabolism | Receptors, Tumor Necrosis Factor, Type I - genetics | Reverse Transcriptase Polymerase Chain Reaction | Glycogen Synthase Kinase 3 beta - metabolism | Blotting, Western | Mice, Knockout | Muscle Proteins - genetics | Animals | Hydroxycholesterols | Muscle, Skeletal - pathology | Insulin-Like Growth Factor I - metabolism
Journal Article
FEBS Letters, ISSN 0014-5793, 03/2010, Volume 584, Issue 6, pp. 1143 - 1148
Oxysterols activating liver X receptors (LXRs) repress expression of pro-inflammatory genes and have anti-inflammatory effects. Here, we show for the first... 
IgE receptor | Nuclear receptor | Mast cell | Cell degranulation | Cytokine production | SREBP | high-affinity IgE | LXR | 22(R)-OHC | 22(R)-hydroxycholesterol | 24(S),25-EC | LDL receptor | 22(S)-OHC | 25-hydroxycholesterol | 25-OHC | 24(S),25-epoxycholesterol | BMMCs | 22(S)-hydroxycholesterol | bone marrow-derived mast cells | FcεRI | liver X receptor | LDLR | sterol regulatory element-binding protein | endoplasmic reticulum | LIPID-METABOLISM | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | ENDOPLASMIC-RETICULUM STRESS | BETA | CELL BIOLOGY | BIOPHYSICS | LIGANDS | STEROL REGULATORY ELEMENT | INFLAMMATION | EXPRESSION | Bone Marrow Cells - physiology | Antibody Affinity - drug effects | Orphan Nuclear Receptors - metabolism | Bone Marrow Cells - immunology | Liver X Receptors | Orphan Nuclear Receptors - physiology | Mast Cells - metabolism | Bone Marrow Cells - drug effects | Interleukin-6 - metabolism | Sterols - pharmacology | Mast Cells - immunology | Receptors, IgE - physiology | Mice, Inbred C57BL | Orphan Nuclear Receptors - agonists | Cells, Cultured | Mast Cells - physiology | Down-Regulation - drug effects | Hydroxycholesterols - pharmacology | Mast Cells - drug effects | Cholestanols - pharmacology | Animals | Receptors, IgE - metabolism | Signal Transduction - drug effects | Signal Transduction - physiology | Mice | Bone Marrow Cells - metabolism | Cell Degranulation - drug effects
Journal Article
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