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Cell, ISSN 0092-8674, 2009, Volume 136, Issue 4, pp. 701 - 718
Journal Article
EMBO JOURNAL, ISSN 0261-4189, 07/1994, Volume 13, Issue 14, pp. 3356 - 3367
We have isolated and determined the protein composition of the spliceosomal complex C. The pre-mRNA in this complex has undergone catalytic step I, but not... 
2ND REACTION | SITE SELECTION | ACTIVE-SITE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PREMESSENGER RNA | SACCHAROMYCES-CEREVISIAE | SPLICEOSOMAL COMPLEXES | U6 SNRNA | CELL BIOLOGY | MESSENGER-RNA | MAMMALIAN SPLICEOSOME | SPLICING REACTION | SMALL NUCLEAR RIBONUCLEOPROTEIN | YEAST PRP8 PROTEIN
Journal Article
Journal Article
Genes and Development, ISSN 0890-9369, 04/1999, Volume 13, Issue 7, pp. 841 - 850
Journal Article
RNA, ISSN 1355-8382, 08/1995, Volume 1, Issue 6, pp. 584 - 597
For the second catalytic step of pre-mRNA splicing to occur, a 3' splice site must be selected and juxtaposed with the 5' exon. Four proteins, Prp16p, Slu7p,... 
2ND REACTION | LARIAT FORMATION | PROTEIN | U5 SNRNP | BIOCHEMISTRY & MOLECULAR BIOLOGY | PREMESSENGER RNA | UV CROSS-LINKING | SACCHAROMYCES-CEREVISIAE | SNRNP-SNRNP INTERACTIONS | YEAST | RNA-DEPENDENT ATPASE | SMALL NUCLEAR RIBONUCLEOPROTEIN | BINDING
Journal Article
Nature Structural & Molecular Biology, ISSN 1545-9993, 12/2009, Volume 16, Issue 12, pp. 1237 - 1243
The spliceosome is a ribonucleoprotein machine that removes introns from pre-mRNA in a two-step reaction. To investigate the catalytic steps of splicing, we... 
2ND REACTION | PRP2 | ACTIVATION | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMPLEXES | PRE-MESSENGER-RNA | CELL BIOLOGY | BIOPHYSICS | DEPENDENT ATPASE | INTERACTS | SLU7 | CATALYTIC STEPS | Adenosine Triphosphatases - isolation & purification | RNA Helicases - metabolism | DEAD-box RNA Helicases - isolation & purification | RNA Splicing Factors | Adenosine Triphosphatases - metabolism | Ribonucleoprotein, U5 Small Nuclear - metabolism | Ribonucleoprotein, U2 Small Nuclear - isolation & purification | Spliceosomes - ultrastructure | RNA, Fungal - metabolism | Saccharomyces cerevisiae - metabolism | Spliceosomes - metabolism | Ribonucleoprotein, U2 Small Nuclear - metabolism | Image Processing, Computer-Assisted | Microscopy, Electron - methods | Models, Biological | Saccharomyces cerevisiae Proteins - metabolism | Saccharomyces cerevisiae Proteins - isolation & purification | RNA, Fungal - isolation & purification | DEAD-box RNA Helicases - metabolism | RNA Helicases - isolation & purification | Ribonucleoprotein, U5 Small Nuclear - isolation & purification | Ribonucleoproteins, Small Nuclear - isolation & purification | Ribonucleoproteins, Small Nuclear - metabolism | Ribonucleoproteins | Physiological aspects | Genetic aspects | Research | Structure | Brewer's yeast | Health aspects | RNA splicing | Proteins | Catalysis | Mutation | Molecular structure | Molecular biology
Journal Article