X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (358432) 358432
Publication (34305) 34305
Book / eBook (21201) 21201
Conference Proceeding (5151) 5151
Dissertation (4447) 4447
Book Chapter (3856) 3856
Book Review (2651) 2651
Report (1593) 1593
Magazine Article (1247) 1247
Music Score (1090) 1090
Government Document (1042) 1042
Web Resource (986) 986
Newspaper Article (845) 845
Paper (315) 315
Data Set (144) 144
Journal / eJournal (138) 138
Trade Publication Article (125) 125
Manuscript (124) 124
Painting (65) 65
Streaming Video (63) 63
Art (57) 57
Reference (40) 40
Exam (19) 19
Microfilm (12) 12
Newsletter (10) 10
Technical Report (8) 8
Standard (7) 7
Drawing (4) 4
Compact Disc (3) 3
Computer File (2) 2
Graphic Arts (2) 2
Photograph (2) 2
Poster (2) 2
Streaming Audio (2) 2
Video Recording (2) 2
Archival Material (1) 1
Audio Recording (1) 1
Map (1) 1
Music Recording (1) 1
Presentation (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (118930) 118930
animals (99673) 99673
index medicus (97876) 97876
male (58233) 58233
female (49092) 49092
mice (42404) 42404
biochemistry & molecular biology (40037) 40037
apoptosis (33535) 33535
rats (30938) 30938
expression (28292) 28292
cell biology (27924) 27924
adult (21118) 21118
analysis (20731) 20731
middle aged (20406) 20406
cells, cultured (19795) 19795
phosphorylation (19458) 19458
oncology (19289) 19289
activation (18826) 18826
caspase 3 - metabolism (18561) 18561
proteins (18339) 18339
signal transduction (18155) 18155
cell line, tumor (18115) 18115
apoptosis - drug effects (17730) 17730
gene expression (16693) 16693
research (16503) 16503
neurosciences (16176) 16176
cell line (15831) 15831
pharmacology & pharmacy (15078) 15078
cancer (14780) 14780
aged (14517) 14517
molecular sequence data (14386) 14386
article (14131) 14131
immunology (13239) 13239
cells (12618) 12618
base sequence (11797) 11797
rna, messenger - metabolism (10679) 10679
mutation (10468) 10468
research article (10381) 10381
caspase 3 (10312) 10312
3' untranslated regions (10301) 10301
time factors (10248) 10248
rats, sprague-dawley (10120) 10120
chemistry (10111) 10111
gene-expression (9822) 9822
mice, inbred c57bl (9717) 9717
blotting, western (9711) 9711
grade 3 (9687) 9687
mitogen-activated protein kinase 1 - metabolism (9490) 9490
physiological aspects (9475) 9475
genetic aspects (9413) 9413
dose-response relationship, drug (9411) 9411
inflammation (9390) 9390
amino acid sequence (9376) 9376
inhibition (9204) 9204
oxidative stress (9198) 9198
protein (9107) 9107
multidisciplinary sciences (9048) 9048
genetics & heredity (8936) 8936
physiology (8895) 8895
immunohistochemistry (8887) 8887
mitogen-activated protein kinase 3 - metabolism (8509) 8509
signal transduction - drug effects (8491) 8491
growth (8459) 8459
health aspects (8340) 8340
genes (8336) 8336
cell proliferation (8278) 8278
protein binding (8212) 8212
disease models, animal (8160) 8160
in-vitro (8158) 8158
gene (8157) 8157
endocrinology & metabolism (8135) 8135
rna, messenger - genetics (8003) 8003
chemistry, multidisciplinary (7975) 7975
identification (7924) 7924
transfection (7904) 7904
history (7845) 7845
kinases (7646) 7646
medicine, research & experimental (7591) 7591
caspases - metabolism (7586) 7586
kinetics (7577) 7577
medicine (7554) 7554
biophysics (7350) 7350
enzyme activation (7348) 7348
chemistry, organic (7026) 7026
adolescent (6875) 6875
biology (6857) 6857
gene expression regulation (6854) 6854
3次元 (6828) 6828
enzyme inhibitors - pharmacology (6693) 6693
hematology (6656) 6656
child (6647) 6647
in-vivo (6644) 6644
proliferation (6641) 6641
life sciences (6633) 6633
cell survival - drug effects (6600) 6600
science (6577) 6577
rna (6540) 6540
cell proliferation - drug effects (6496) 6496
binding sites (6494) 6494
mice, knockout (6464) 6464
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Robarts - Stacks (13570) 13570
UofT at Mississauga - Stacks (3510) 3510
UTL at Downsview - May be requested (3423) 3423
Collection Dvlpm't (Acquisitions) - Vendor file (3066) 3066
UofT at Scarborough - Stacks (2624) 2624
Victoria University E.J. Pratt - Stacks (2343) 2343
St. Michael's College (John M. Kelly) - 2nd Floor (2037) 2037
Trinity College (John W Graham) - Stacks (1672) 1672
Gerstein Science - Stacks (1600) 1600
Pontifical Inst. Mediaeval Studies - Library use only (1281) 1281
Collection Dvlpm't (Acquisitions) - Closed Orders (1020) 1020
Music - Stacks (830) 830
Online Resources - Online (805) 805
St. Michael's College (John M. Kelly) - 3rd Floor (775) 775
OISE - Stacks (734) 734
Engineering & Comp. Sci. - Stacks (605) 605
Innis College - Stacks (465) 465
New College (Ivey) - Stacks (316) 316
Law (Bora Laskin) - Stacks (299) 299
Regis College - Stacks (242) 242
Victoria University Emmanuel College - Stacks (230) 230
Knox College (Caven) - Stacks (216) 216
St. Augustine's Seminary - Stacks (194) 194
Victoria University CRRS - Library use only (164) 164
Faculty of Information - Stacks (162) 162
Mathematical Sciences - Stacks (139) 139
Royal Ontario Museum - Stacks (139) 139
University College (Laidlaw) - Stacks (136) 136
Victoria University E.J. Pratt - Reference (135) 135
Earth Sciences (Noranda) - Stacks (106) 106
Pontifical Inst. Mediaeval Studies - Guest (99) 99
Indust. Rel's & Hum. Resources (Newman) - Library use only (98) 98
Institute for Christian Studies - Stacks (94) 94
Trinity College (John W Graham) - Storage (90) 90
Physics - Stacks (78) 78
Robarts - Reference (69) 69
UofT Schools - Stacks (69) 69
Thomas Fisher Rare Book - Rare Book (65) 65
Trinity College (John W Graham) - Reference (61) 61
Architecture Landscape (Shore + Moffat) - Stacks (59) 59
UofT at Scarborough - Withdrawn (58) 58
Robarts - Storage (57) 57
Robarts - Searching (50) 50
Art - Library use only (46) 46
Robarts - Library use only (44) 44
Media Commons - Microtexts (40) 40
Business (Joseph L Rotman) - Stacks (38) 38
OISE - Curriculum Resources (37) 37
St. Michael's College (John M. Kelly) - Reference (36) 36
Criminology - Stacks (35) 35
Robarts - Not Returned (29) 29
Astronomy & Astrophysics - Ask at library (27) 27
Victoria University E.J. Pratt - Oversize (27) 27
UofT at Mississauga - Reference (25) 25
Chemistry (A D Allen) - Stacks (24) 24
Collection Dvlpm't (Acquisitions) - Cancelled Order (24) 24
Robarts - Government Pubs (22) 22
Pontifical Inst. Mediaeval Studies - Reference (21) 21
Robarts - Course Reserves (21) 21
Robarts - May be requested in 6-10 wks (21) 21
OISE - Missing (20) 20
East Asian (Cheng Yu Tung) - Stacks (19) 19
Robarts - In process for Downsview (19) 19
Royal Ontario Museum - Far Eastern (18) 18
UofT at Mississauga - Missing (18) 18
Baycrest Hospital - Stacks (17) 17
Holland Bloorview Kids Rehabilitation - Stacks (17) 17
Gerstein Science - Missing (16) 16
Thomas Fisher Rare Book - May be requested at Fisher (16) 16
Aerospace - Stacks (15) 15
Music - Donations processing (15) 15
OISE - May be requested in 6-10 wks (15) 15
Providence Healthcare - Stacks (15) 15
UofT Schools - Special Collections (15) 15
Engineering & Comp. Sci. - May be requested in 6-10 wks (14) 14
UofT at Scarborough - May be requested in 6-10 wks (14) 14
Art - Deshman (13) 13
Law (Bora Laskin) - Reserve desk (13) 13
Regis College - Storage (13) 13
Royal Ontario Museum - Periodical Stacks (13) 13
St. Augustine's Seminary - Reference (13) 13
UofT at Mississauga - May be requested in 6-10 wks (13) 13
Baycrest Hospital - Resident/Client Library (12) 12
Collection Dvlpm't (Acquisitions) - On order (12) 12
OISE - Lost (12) 12
Trinity College (John W Graham) - Wycliffe Storage (12) 12
Gerstein Science - Circulation Desk (11) 11
Gerstein Science - Reference (11) 11
Regis College - Reference (11) 11
Victoria University Emmanuel College - Reference (11) 11
Music - Protected Material (10) 10
St. Michael's Hospital - Stacks (10) 10
Engineering & Comp. Sci. - Missing (9) 9
Innis College - Searching (9) 9
Physics - Reference (9) 9
Robarts - Moving to offsite: no requests (9) 9
Robarts - Processing (9) 9
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (9) 9
Trinity College (John W Graham) - Oversize (9) 9
Trinity College (John W Graham) - Periodical Stacks (9) 9
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (361357) 361357
Japanese (20262) 20262
Chinese (10670) 10670
German (6430) 6430
French (2867) 2867
Spanish (1838) 1838
Korean (1474) 1474
Portuguese (1132) 1132
Russian (968) 968
Italian (577) 577
Latin (495) 495
Danish (358) 358
Swedish (323) 323
Polish (213) 213
Czech (165) 165
Turkish (134) 134
Dutch (100) 100
Norwegian (89) 89
Arabic (86) 86
Persian (77) 77
Hungarian (64) 64
Catalan (57) 57
Indonesian (57) 57
Hebrew (44) 44
Croatian (38) 38
Greek (28) 28
Ukrainian (27) 27
Afrikaans (21) 21
Bulgarian (21) 21
Finnish (19) 19
Romanian (13) 13
Slovak (13) 13
Slovenian (13) 13
Lithuanian (12) 12
Icelandic (11) 11
Serbian (9) 9
Urdu (6) 6
Macedonian (5) 5
Malay (4) 4
Ndonga (4) 4
Welsh (4) 4
Bosnian (3) 3
Irish (3) 3
Yiddish (3) 3
Albanian (2) 2
Azerbaijani (2) 2
Bengali (2) 2
Hindi (2) 2
Nepali (2) 2
Ottoman (2) 2
Quechua (2) 2
Sanskrit (2) 2
Tagalog (2) 2
Avestan (1) 1
Chechen (1) 1
Fijian (1) 1
Galician (1) 1
Kurdish (1) 1
Norwegian Nynorsk (1) 1
Occitan (1) 1
Panjabi (1) 1
Romansh (1) 1
Tahitian (1) 1
Telugu (1) 1
Tibetan (1) 1
Venda (1) 1
Western Frisian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Medicinal Chemistry, ISSN 0022-2623, 05/2016, Volume 59, Issue 10, pp. 4926 - 4947
Journal Article
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 07/2017, Volume 60, Issue 13, pp. 5857 - 5867
Blockade of the PD-1/PD-L1 immune checkpoint pathway with monoclonal antibodies has provided significant advances in cancer treatment. The antibody-based... 
unclassified drug | protein interaction | 4 [[[4 [[3 (2,3 dihydro 1,4 benzodioxin 6 yl) 2methylphenyl]methoxy] 2,5 difluorophenyl]methyl]amino] 3 hydroxybutanoic acid hydrochloride | drug synthesis | 3 [4 chloro 5 [[3 (2,3 dihydro 1,4 benzodioxin 6 yl) 2 methylphenyl]methoxy] 2 formylphenoxymethyl]benzonitrile | 4 [[3 (2,3 dihydro 1,4 benzodioxin 6 yl) 2 methylphenyl]methoxy] 2,5 difluorobenzaldehyde | drug structure | protein function | 2 [[[2,6 dimethoxy 4 [(2 methyl 3 phenylphenyl)methoxy]phenyl]methyl]amino] 3 methylbutan 1 ol hydrochloride | X ray analysis | 2 [[[2 [(3 cyanophenyl)methoxy] 4 [[3 (2,3 dihydro 1,4 benzodioxin 6 yl) 2 methylphenyl]methoxy] 5 methylphenyl] methyl]amino] 3 hydroxypropanoic acid hydrochloride | 1 [[3 bromo 4 [(2 methyl 3 phenylphenyl)methoxy]phenyl]methyl]piperidine 2 carboxylic acid | protein structure | oligomerization | 4 [[3 (2,3 dihydro 1,4 benzodioxin 6 yl) 2 methylphenyl]methoxy] 2 hydroxy 5 methylbenzaldehyde | drug determination | 3 [5 [[3 (2,3 dihydro 1,4 benzodioxin 6 yl) 2 methylphenyl]methoxy] 2 formyl 4 methylphenoxymethyl]benzonitrile | IC50 | immunomodulating agent | 2,6 dimethoxy 4 [(2 methyl 3 phenylphenyl)methoxy]benzaldehyde | 5 chloro 4 [[3 (2,3 dihydro 1,4 benzodioxin 6 yl) 2 methylphenyl]methoxy] 2 hydroxybenzaldehyde | human | protein expression | [3 (2,3 dihydro 1,4 benzodioxin 6 yl) 2 methylphenyl]methanol | n [2 [[[2 methoxy 6 [(2 methyl 3 phenylphenyl)methoxy]pyridin 3 yl]methyl]amino]ethyl]acetamide hydrochloride | 3 bromo 4 [(2 methyl 3 phenylphenyl)methoxy]benzaldehyde | dimerization | nuclear magnetic resonance spectroscopy | programmed death 1 ligand 1 | heteronuclear multiple quantum coherence | 1 [[5 chloro 2 [(3 cyanophenyl)methoxy] 4 [[3 (2,3 dihydro 1,4 benzodioxin 6 yl) 2 methylphenyl]methoxy]phenyl] methyl] 4 hydroxypyrrolidine 2 carboxylic acid hydrochloride | protein inhibitor | (2 methyl 3 biphenylyl)methanol | article | To be checked by Faculty | hydrophobicity | 2 methoxy 6 [(2 methyl 3 phenylphenyl)methoxy]pyridine 3 carbaldehyde | cancer immunotherapy | crystallization | COMPLEX | CHEMISTRY, MEDICINAL | THERAPY | CANCER-IMMUNOTHERAPY | MONOCLONAL-ANTIBODIES | DERIVATIVES | CHECKPOINT BLOCKADE | Small Molecule Libraries - pharmacology | Programmed Cell Death 1 Receptor - chemistry | Protein Interaction Maps - drug effects | Humans | Programmed Cell Death 1 Receptor - metabolism | Crystallography, X-Ray | Programmed Cell Death 1 Receptor - antagonists & inhibitors | B7-H1 Antigen - chemistry | Small Molecule Libraries - chemistry | B7-H1 Antigen - metabolism | B7-H1 Antigen - antagonists & inhibitors | Molecular Docking Simulation | Protein Multimerization - drug effects
Journal Article
Letters in Drug Design and Discovery, ISSN 1570-1808, 2016, Volume 13, Issue 1, pp. 64 - 76
A series of 6,7-disubstituted-3-{2-[4-(substituted) piperazin-1-yl]-2-oxoethyl}quinazoline-2,4(1H, 3H)-dione derivatives (7-34) were synthesized and their... 
Cytotoxicity | Sulforhodamine B method | Quinazoline | Anticancer | Quinazoline-2,4(1H,3H)-dione | Piperazine | SUBSTITUTED QUINAZOLINEDIONES | DESIGN | CHEMISTRY, MEDICINAL | AMPA | PROTEIN | piperazine | sulforhodamine B method | ANTICONVULSANT | anticancer | QUINAZOLINE-2,4-DIONE | IN-VITRO | DNA GYRASE | INHIBITORS | TOPOISOMERASE-IV | cytotoxicity | quinazoline-2,4(1H,3H)-dione
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 12/2018, Volume 61, Issue 24, pp. 11021 - 11036
Spinal muscular atrophy (SMA), a rare neuromuscular disorder, is the leading genetic cause of death in infants and toddlers. SMA is caused by the deletion or a... 
CHEMISTRY, MEDICINAL | MODIFIERS | IDENTIFICATION | SINGLE NUCLEOTIDE
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 01/2016, Volume 108, pp. 301 - 308
Journal Article
Journal Article
Journal Article