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3 alpha-hydroxysteroid dehydrogenase (63) 63
biochemistry & molecular biology (60) 60
3α-hydroxysteroid dehydrogenase (49) 49
animals (44) 44
humans (40) 40
index medicus (36) 36
rats (33) 33
3 alpha -hydroxysteroid dehydrogenase (32) 32
expression (30) 30
pharmacology & pharmacy (25) 25
endocrinology & metabolism (23) 23
3-hydroxysteroid dehydrogenases - metabolism (22) 22
male (22) 22
female (21) 21
liver (21) 21
dihydrodiol dehydrogenase (19) 19
3-alpha-hydroxysteroid dehydrogenase (17) 17
aldo-keto reductase (16) 16
molecular-cloning (16) 16
neurosteroids (16) 16
toxicology (16) 16
neurosciences (15) 15
testosterone (15) 15
enzymes (14) 14
messenger-rna (14) 14
progesterone (14) 14
cell biology (13) 13
kinetics (13) 13
tissue distribution (13) 13
20-alpha-hydroxysteroid dehydrogenase (12) 12
3-hydroxysteroid dehydrogenases - genetics (12) 12
5 alpha-reductase (12) 12
allopregnanolone (12) 12
mice (12) 12
steroids (12) 12
3-oxo-5-alpha-steroid 4-dehydrogenase - metabolism (11) 11
biophysics (11) 11
brain (11) 11
keto reductase superfamily (11) 11
neurosteroid (11) 11
binding sites (10) 10
gene expression (10) 10
rna, messenger - metabolism (10) 10
3-alpha-hydroxysteroid dehydrogenase - metabolism (9) 9
chemistry, medicinal (9) 9
comamonas testosteroni (9) 9
enzyme inhibitors - pharmacology (9) 9
gene (9) 9
liver - enzymology (9) 9
reductase (9) 9
substrate specificity (9) 9
3^a-hydroxysteroid dehydrogenase (8) 8
5α-reductase (8) 8
apoptosis (8) 8
biotechnology & applied microbiology (8) 8
cytosol (8) 8
dehydrogenase (8) 8
hydroxysteroid dehydrogenase (8) 8
inhibition (8) 8
metabolism (8) 8
neuroactive steroids (8) 8
purification (8) 8
rats, sprague-dawley (8) 8
rna, messenger - genetics (8) 8
3-hydroxysteroid dehydrogenases - chemistry (7) 7
acid-binding protein (7) 7
amino acid sequence (7) 7
androgens (7) 7
biochemical research methods (7) 7
cancer (7) 7
cell line (7) 7
cells, cultured (7) 7
chemistry, analytical (7) 7
crystal-structure (7) 7
gene-expression (7) 7
molecular sequence data (7) 7
oxidoreductases - metabolism (7) 7
superfamily (7) 7
5 alpha-reductase 1 (6) 6
alcohol oxidoreductases - metabolism (6) 6
aldehyde reductase (6) 6
carbonyl reductase (6) 6
central-nervous-system (6) 6
cloning (6) 6
identification (6) 6
isoenzymes - metabolism (6) 6
leydig-cells (6) 6
models, molecular (6) 6
physiological aspects (6) 6
pregnancy (6) 6
progesterone - metabolism (6) 6
prostate (6) 6
rat (6) 6
rat-brain (6) 6
recombinant proteins - genetics (6) 6
research (6) 6
retinol dehydrogenase 2 (6) 6
steroids - metabolism (6) 6
20 alpha-hydroxysteroid dehydrogenase (5) 5
20α-hydroxysteroid dehydrogenase (5) 5
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Journal Article
Biochemical Journal, ISSN 0264-6021, 04/2016, Volume 473, Issue 8, pp. 1037 - 1046
Journal Article
Molecular Pain, ISSN 1744-8069, 8/2015, Volume 11, p. 46
Background Koumine is an alkaloid monomer found abundantly in Gelsemium plants. It has been shown to reverse thermal hyperalgesia and mechanical allodynia... 
Neurosteroids | PROGESTERONE | Koumine | GELSEMIUM-ELEGANS BENTH | NEUROSTEROID ALLOPREGNANOLONE | INVOLVEMENT | POSSIBLE MECHANISM | NERVE INJURY | NEUROSCIENCES | DEHYDROGENASE | Neuropathic pain | Allopregnanolone | 3 alpha-Hydroxysteroid dehydrogenase | MICROGLIA | INFLAMMATORY PAIN | SEPARATION | Immunohistochemistry | Analgesics - pharmacology | Gene Expression Regulation, Enzymologic - drug effects | Neuralgia - complications | Neuralgia - genetics | Spinal Cord - drug effects | Indole Alkaloids - therapeutic use | Medroxyprogesterone Acetate - pharmacology | Male | Indole Alkaloids - administration & dosage | RNA, Messenger - metabolism | Hyperalgesia - pathology | 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific) - genetics | Biocatalysis - drug effects | Spinal Cord - pathology | Injections, Subcutaneous | Sciatic Nerve - drug effects | Indole Alkaloids - chemistry | Disease Models, Animal | Analgesics - therapeutic use | Constriction | Sciatic Nerve - pathology | Hyperalgesia - complications | RNA, Messenger - genetics | Spinal Cord - enzymology | Neuralgia - enzymology | Rats, Sprague-Dawley | Neuralgia - drug therapy | Spinal Cord Dorsal Horn - enzymology | Spinal Cord Dorsal Horn - drug effects | Animals | Spinal Cord Dorsal Horn - pathology | Hyperalgesia - drug therapy | 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific) - metabolism | Indole Alkaloids - pharmacology | 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific) - antagonists & inhibitors | Chronic Disease | Sciatic Nerve - enzymology
Journal Article
Protein Expression and Purification, ISSN 1046-5928, 11/2015, Volume 115, pp. 102 - 108
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 2009, Volume 178, Issue 1, pp. 215 - 220
3α-Hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni is a key enzyme in the degradation of steroids in the environment. The encoding... 
Steroid determination | Comamonas testosteroni | 3α-Hydroxysteroid dehydrogenase/carbonyl reductase | Biosensor | 3 alpha-Hydroxysteroid dehydrogenase/carbonyl reductase | GENE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHARMACOLOGY & PHARMACY | TOXICOLOGY | BACTERIUM COMAMONAS-TESTOSTERONI
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 2010, Volume 45, Issue 11, pp. 5309 - 5317
Journal Article
Journal Article