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Nanomedicine: Nanotechnology, Biology, and Medicine, ISSN 1549-9634, 2015, Volume 11, Issue 8, pp. 2013 - 2023
Abstract An appropriate representation of the tumor microenvironment in tumor models can have a pronounced impact on directing combinatorial treatment... 
Internal Medicine | Targeted nanoparticle | 3D co-cultures | Tumor microenvironment | Galectin-1 | 3 dimensional triple negative breast cancer (3D TNBC) model | Tumor tissue analogs (TTA) | Tumor cell spheroids | MEDICINE, RESEARCH & EXPERIMENTAL | SOLID TUMORS | INDUCED APOPTOSIS | DRUG-DELIVERY | DNA-DAMAGE | P38 MAPK | STEM-CELL NICHE | NANOSCIENCE & NANOTECHNOLOGY | ARSENIC TRIOXIDE | BREAST-CANCER | CROSS-TALK | ENDOTHELIAL-CELLS | Nanoparticles - chemistry | Spheroids, Cellular - pathology | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Triple Negative Breast Neoplasms - drug therapy | Cisplatin - administration & dosage | Drug Delivery Systems | Tumor Cells, Cultured - pathology | Arsenicals - therapeutic use | Galectin 1 - analysis | Triple Negative Breast Neoplasms - pathology | Female | Spheroids, Cellular - drug effects | Breast - pathology | Oxides - administration & dosage | Disease Models, Animal | Breast - radiation effects | Oxides - therapeutic use | Tumor Microenvironment - drug effects | Tumor Cells, Cultured - drug effects | Coculture Techniques - methods | Fibroblasts - pathology | Tumor Microenvironment - radiation effects | Arsenicals - administration & dosage | Animals | Cisplatin - therapeutic use | Breast - drug effects | Mice, Nude | Fibroblasts - drug effects | Mice | Endothelial Cells - pathology | Triple Negative Breast Neoplasms - radiotherapy | Endothelial Cells - drug effects | Chemotherapy | Arsenic | Nanotechnology | Radiation | Cancer | Tumors | targeted nanoparticle | 3 dimensional Triple negative breast cancer (3D TNBC) model | tumor microenvironment | galectin-1
Journal Article
Molecules, ISSN 1420-3049, 2018, Volume 23, Issue 3, p. 678
Journal Article
Oncogene, ISSN 0950-9232, 01/2017, Volume 36, Issue 1, pp. 122 - 132
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 4456 - 16
Collagen prolyl 4-hydroxylase (P4H) expression and collagen hydroxylation in cancer cells are necessary for breast cancer progression. Here, we show that P4H... 
EPITHELIAL-MESENCHYMAL TRANSITION | LACTATE-DEHYDROGENASE | HYPOXIA-INDUCIBLE FACTOR | BREAST-CANCER CELLS | PYRUVATE-DEHYDROGENASE KINASE | MULTIDISCIPLINARY SCIENCES | HEMATOPOIETIC STEM-CELLS | EXTRACELLULAR-MATRIX | DRUG-RESISTANCE | FACTOR-I | HIF-ALPHA | Reactive Oxygen Species - metabolism | Humans | Drug Resistance, Neoplasm | RNA, Messenger - metabolism | Gene Knockdown Techniques | Procollagen-Proline Dioxygenase - metabolism | Triple Negative Breast Neoplasms - physiopathology | Neoplastic Stem Cells - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Neoplasm Metastasis - prevention & control | Triple Negative Breast Neoplasms - pathology | Procollagen-Proline Dioxygenase - antagonists & inhibitors | Female | Ketoglutaric Acids - metabolism | Triple Negative Breast Neoplasms - enzymology | Cell Line | Gene Expression | Neoplasm Recurrence, Local - metabolism | Neoplasm Recurrence, Local - prevention & control | Mice, SCID | Collagen - metabolism | Animals | Procollagen-Proline Dioxygenase - genetics | Triple Negative Breast Neoplasms - metabolism | Survival Analysis | Mice | Neoplastic Stem Cells - enzymology | Hypoxia-inducible factors | Hypoxia-inducible factor 1 | Phosphorylation | Hydroxylation | Xenotransplantation | Hydroxylase | Chemoresistance | Collagens | Proline | Breast cancer | Kinases | Doxorubicin | ErbB-2 protein | Proteins | Chemotherapy | Oxidative phosphorylation | Collagen | Xenografts | Breast | Hypoxia | Procollagen-proline dioxygenase | Cancer
Journal Article
Cancer Cell, ISSN 1535-6108, 02/2018, Volume 33, Issue 2, pp. 187 - 201.e10
Journal Article