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Archives of Biochemistry and Biophysics, ISSN 0003-9861, 04/2013, Volume 532, Issue 2, pp. 103 - 113
► [E43S]SNase retains the DNA-binding ability but loses its catalytic activity. ► Binding of ssDNA/Cd to [E43S]SNase induced dynamics changes. ► Solution... 
NMR | DNA hydrolysis | Modeling | Backbone dynamics | Staphylococcal nuclease | MAGNETIC-RESONANCE RELAXATION | SEQUENCE-SPECIFIC ASSIGNMENTS | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMICAL-SHIFT | CONTEMPORARY ENZYMOLOGY | PROTEIN STRUCTURES | 3',5'-BISPHOSPHATE-CA-2+ TERNARY COMPLEX | BIOPHYSICS | HETERONUCLEAR NMR-SPECTROSCOPY
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 2004, Volume 343, Issue 2, pp. 305 - 312
A human 3′-5′-exoribonuclease (3′hExo) has recently been identified and shown to be responsible for histone mRNA degradation. Functionally, 3′hExo and a... 
3′-5′ DEDDh exoribonuclease | bound nucleotide conformation | active-site pocket | hydrolytic cleavage mechanism | REFINEMENT | REPLICATION | RNA | DNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | 3 '-5 ' DEDDh exoribonuclease | BNL | national synchrotron light source | BASIC BIOLOGICAL SCIENCES | NUCLEASES | MOLECULAR BIOLOGY
Journal Article
DNA Repair, ISSN 1568-7864, 07/2014, Volume 19, pp. 95 - 107
To avoid genome instability, DNA repair nucleases must precisely target the correct damaged substrate before they are licensed to incise. Damage identification... 
FEN1 | Genome maintenance | RNA | UVDE | Metals | DNase | Crystallography | DNA repair | Base excision repair | Telomere | Nfi | Double strand break repair | Exonuclease | Mre11 | Exo1 | Mismatch repair | Nfo | Magnesium | RNase | Nucleases | Enzyme–DNA complex | APE1 | Zinc | Structure-specific nuclease | Vsr | TDP2 | DNA | Endonucleases | Nucleotide incision repair | EndoIV | EndoV | Manganese | Enzyme-DNA complex | HUMAN FLAP ENDONUCLEASE-1 | ESCHERICHIA-COLI | SACCHAROMYCES-CEREVISIAE | BASE EXCISION-REPAIR | STRUCTURAL BASIS | GENETICS & HEREDITY | TOXICOLOGY | 3'-5' EXONUCLEASE ACTIVITY | CRYSTAL-STRUCTURE | STRAND-BREAK REPAIR | SUBSTRATE-SPECIFICITY | APURINIC/APYRIMIDINIC ENDONUCLEASE | Deoxyribonuclease (Pyrimidine Dimer) - chemistry | Transcription Factors - chemistry | Humans | Multienzyme Complexes - genetics | DNA Repair - genetics | Endodeoxyribonucleases - chemistry | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Nuclear Proteins - chemistry | DNA-Binding Proteins - chemistry | DNA-(Apurinic or Apyrimidinic Site) Lyase - chemistry | Multienzyme Complexes - chemistry | DNA-(Apurinic or Apyrimidinic Site) Lyase - genetics | Endodeoxyribonucleases - genetics | Deoxyribonuclease IV (Phage T4-Induced) - chemistry | Deoxyribonuclease (Pyrimidine Dimer) - genetics | DNA Damage - genetics | Protein Conformation | Flap Endonucleases - chemistry | Deoxyribonuclease IV (Phage T4-Induced) - genetics | Nuclear Proteins - genetics | Nucleic Acid Conformation | Flap Endonucleases - genetics | DNA replication | DNA damage | Analysis | Ribonuclease | DNA binding proteins | Index Medicus | Nucleotide Incision Repair
Journal Article
International Journal for Parasitology, ISSN 0020-7519, 2008, Volume 38, Issue 5, pp. 513 - 526
Journal Article
PROTEIN SCIENCE, ISSN 0961-8368, 01/2002, Volume 11, Issue 1, pp. 82 - 91
Pulsed hydrogen exchange methods were used to follow the formation of structure during the refolding of acid-denatured staphylococcal nuclease containing a... 
PROTEIN | hydrogen exchange | SEQUENCE-SPECIFIC ASSIGNMENTS | STABILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | pulse labeling | CYTOCHROME-C | DENATURED STATE | NMR | 3',5'-BISPHOSPHATE-CA-2+ TERNARY COMPLEX | CIRCULAR-DICHROISM | staphylococcal nuclease | PROLINE MUTATIONS | MAGNETIC-RESONANCE | protein folding | deoxyribonuclease
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 07/2014, Volume 450, Issue 1, pp. 634 - 640
The RNase D-type 3′–5′ exonuclease Rrp6p from is a nuclear-specific cofactor of the RNA exosome and associates with Rrp47p (Lrp1p). Here, we show using... 
RNA turnover | RNA processing | Exosome | Ribosomal RNA | 3′–5′ nuclease | snoRNA | 3′-5′ nuclease | 3 '-5 ' nuclease | SUBUNIT RRP6P | DOMAIN | PROTEIN | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | EUKARYOTIC EXOSOME | RRP47P | MUTANTS | BIOPHYSICS | RNA EXOSOME | PACKAGE | DEGRADATION | Models, Chemical | Nuclear Proteins - ultrastructure | Molecular Sequence Data | DNA-Binding Proteins - metabolism | Exosome Multienzyme Ribonuclease Complex - chemistry | X-Ray Diffraction | Computer Simulation | RNA - ultrastructure | Exosome Multienzyme Ribonuclease Complex - metabolism | Binding Sites | Exosome Multienzyme Ribonuclease Complex - ultrastructure | RNA - metabolism | Saccharomyces cerevisiae Proteins - ultrastructure | Amino Acid Sequence | RNA-Binding Proteins - chemistry | Models, Molecular | Scattering, Small Angle | Nuclear Proteins - metabolism | Nuclear Proteins - chemistry | RNA - chemistry | DNA-Binding Proteins - chemistry | DNA-Binding Proteins - ultrastructure | RNA-Binding Proteins - ultrastructure | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Protein Conformation | RNA-Binding Proteins - metabolism | Saccharomyces cerevisiae Proteins - chemistry | X-RAY DIFFRACTION | SACCHAROMYCES CEREVISIAE | SYNCHROTRON RADIATION | IN VIVO | RIBOSOMAL RNA | CHROMATOGRAPHY | 60 APPLIED LIFE SCIENCES | MOLECULAR WEIGHT | RNA PROCESSING | ELECTROPHORESIS | AFFINITY | BIOCHEMISTRY | DICHROISM | IN VITRO | LIGHT SCATTERING | SMALL ANGLE SCATTERING | FLUORESCEIN
Journal Article
by Yun, JS and Yoon, JH and Choi, YJ and Son, YJ and Kim, S and Tong, L and Chang, JH
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ISSN 0006-291X, 09/2018, Volume 504, Issue 1, pp. 89 - 95
The decapping exoribonuclease DXO functions in pre-mRNA capping quality control, and shows multiple biochemical activities such as decapping, deNADding,... 
Nuclease inhibitor | HUMAN-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | Adenosine 3',5'-bisphosphate | RNA DECAY | QUALITY-CONTROL MECHANISM | RAI1 | 5'-3' exoribohuclease | ENZYME | CAP | BIOPHYSICS | XRN1 | 5'-3' EXORIBONUCLEASES | DEGRADATION | DXO | DCPS | Crystal
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 2004, Volume 32, Issue 1, pp. 158 - 168
Journal Article
DNA Repair, ISSN 1568-7864, 05/2019, Volume 77, pp. 27 - 35
NME1 (also known as NM23-H1) was the first identified tumor metastasis suppressor, which has been reported to link with genomic stability maintenance and... 
Genomic stability | NHEJ | DNA double-strand breaks | 3′-5′ exonuclease | NME1 | 3 '-5 ' exonuclease | POLYMERASE-MU | PROTEIN-KINASE | HUMAN POLYNUCLEOTIDE KINASE | XRCC4 PROTEIN | DAMAGE RESPONSE | REPAIR | XLF | ARTEMIS NUCLEASE | NM23-H1 | GENETICS & HEREDITY | LIGASE IV | TOXICOLOGY | Medical colleges | DNA damage | Genomics | DNA | Genomes | Metastasis | DNA repair
Journal Article
Journal Article
Journal Article
Journal of Biological Inorganic Chemistry, ISSN 0949-8257, 4/1997, Volume 2, Issue 2, pp. 168 - 176
Metal-mediated hydrolysis of phosphate esters is a common catalytic pathway in nucleic acid biochemistry. Two distinct models are principally invoked in... 
Magnesium | Nuclease | Mechanism | Two-metal-ion | Klenow | two-metal-ion | DNA-POLYMERASE-I | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | magnesium | 3'-5' EXONUCLEASE | HAIRPIN RIBOZYME | CHEMISTRY, INORGANIC & NUCLEAR | 3-DIMENSIONAL STRUCTURE | nuclease | HAMMERHEAD RIBOZYME | BINDING-SITE | ECORV RESTRICTION-ENDONUCLEASE | mechanism | RIBONUCLEASE-H
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 08/2018, Volume 19, Issue 8, p. 2389
Journal Article
Journal Article