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3-aroylindoles (33) 33
index medicus (16) 16
chemistry, organic (15) 15
humans (14) 14
chemistry, medicinal (13) 13
structure-activity relationship (12) 12
antineoplastic agents - pharmacology (11) 11
cell line, tumor (11) 11
combretastatin a-4 analogs (11) 11
antineoplastic agents - chemistry (9) 9
antimitotic agents (8) 8
antineoplastic agents - chemical synthesis (8) 8
inhibitors (8) 8
biological evaluation (7) 7
derivatives (7) 7
drug screening assays, antitumor (7) 7
indoles - chemistry (7) 7
indoles - pharmacology (7) 7
tubulin polymerization (7) 7
binding (6) 6
cancer (6) 6
cell proliferation - drug effects (6) 6
chemistry, multidisciplinary (6) 6
tubulin - metabolism (6) 6
tubulin modulators - pharmacology (6) 6
animals (5) 5
bond activation (5) 5
colchicine (5) 5
indoles - chemical synthesis (5) 5
molecular structure (5) 5
potent (5) 5
tubulin modulators - chemistry (5) 5
3-acylindoles (4) 4
antineoplastic agents (4) 4
binding sites (4) 4
biochemistry & molecular biology (4) 4
chemistry (4) 4
friedel-crafts acylation (4) 4
mice (4) 4
tubulin (4) 4
tubulin modulators - chemical synthesis (4) 4
activation (3) 3
antitumor-activity (3) 3
arylthioindoles (3) 3
c3-acylation (3) 3
catalyzed acylation (3) 3
cytotoxicity (3) 3
discovery (3) 3
drugs (3) 3
green chemistry (3) 3
indole (3) 3
inhibitory concentration 50 (3) 3
medicinal chemistry (3) 3
n-h indoles (3) 3
one-pot (3) 3
one-pot synthesis (3) 3
polymerization (3) 3
potent antitubulin agents (3) 3
synthesis (3) 3
tertiary-amines (3) 3
tubulin - chemistry (3) 3
vascular disrupting agents (3) 3
analogs (2) 2
analysis (2) 2
angiogenesis inhibitors - chemistry (2) 2
angiogenesis inhibitors - pharmacology (2) 2
anticancer (2) 2
anticancer agents (2) 2
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apoptosis - drug effects (2) 2
b16 melanoma cells (2) 2
bis alkaloids (2) 2
bpr0l075 (2) 2
cancer-cells (2) 2
catalysis (2) 2
catalyzed oxidative cyanation (2) 2
cell-growth (2) 2
cells (2) 2
combretastatin a-4 (2) 2
combretastatin a4 (2) 2
cytotoxic evaluation (2) 2
disubstituted 3-aroylindoles (2) 2
docking (2) 2
drug design (2) 2
drug resistance, neoplasm (2) 2
ea.hy 926 endothelial cells (2) 2
efficient (2) 2
functional groups (2) 2
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heterocyclic compounds (2) 2
histone deacetylase inhibitors - pharmacology (2) 2
human umbilical vein endothelial cells - drug effects (2) 2
hydrogen-peroxide (2) 2
hydroxamic acids - pharmacology (2) 2
in-vivo (2) 2
indazoles (2) 2
indoles (2) 2
isoxazole derivatives (2) 2
ligands (2) 2
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Journal of Natural Products, ISSN 0163-3864, 09/2013, Volume 76, Issue 9, pp. 1668 - 1678
Journal Article
Letters in Organic Chemistry, ISSN 1570-1786, 2018, Volume 15, Issue 11, pp. 931 - 939
A series of novel N-substituted-2-amino-3,4,5-trimethoxybenzoylindoles was synthesized and assessed against human cancer cell lines of breast (MCF-7) and colon... 
Combretastatin A-4 | Docking | Synthesis | Anticancer | N-substituted-2-amino-3,4,5-trimethoxybenzoylindole | MCF-7 | synthesis | ASSAY | CHEMISTRY, ORGANIC | MODEL | docking | COMBRETASTATIN A-4 ANALOGS | POTENT ANTIMITOTIC AGENTS | combretastatin A-4 | TUBULIN POLYMERIZATION INHIBITORS | 3-AROYLINDOLES | DERIVATIVES
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 06/2012, Volume 55, Issue 11, pp. 5174 - 5187
Journal Article
Chemical Communications: Chem Comm, ISSN 1359-7345, 01/2015, Volume 51, Issue 85, pp. 15554 - 15557
Magnetic graphitic carbon nitride, Fe-C sub(3)N sub(4), has been synthesized by adorning a graphitic carbon nitride (g-C sub(3)N sub(4)) support with iron... 
Activation | Amines | Catalysts | Iron oxides | Carbon nitride
Journal Article
Chemical Communications, ISSN 1359-7345, 2015, Volume 51, Issue 85, pp. 15554 - 15557
Magnetic graphitic carbon nitride, Fe@g-C3N4, has been synthesized by adorning a graphitic carbon nitride (g-C3N4) support with iron oxide via non-covalent... 
TERTIARY-AMINES | 3-AROYLINDOLES | SODIUM-CYANIDE | GREEN CHEMISTRY | HYDROGEN-PEROXIDE | BOND ACTIVATION | FUTURE | CATALYZED OXIDATIVE CYANATION | CHEMISTRY, MULTIDISCIPLINARY | SUSTAINABLE APPLICATIONS | Amines - chemistry | Magnetic Phenomena | Iron - chemistry | Nitriles - chemistry | Nitriles - chemical synthesis | Molecular Structure | Catalysis
Journal Article
ORGANIC & BIOMOLECULAR CHEMISTRY, ISSN 1477-0520, 02/2020, Volume 18, Issue 8, pp. 1623 - 1628
An efficient regioselective C-3 acylation of free indoles (N-H) has been accomplished via oxidative decarbethoxylation of easily available ethyl arylacetates... 
N-H INDOLES | CARBONYLATION | C-O | ONE-POT | 3-AROYLINDOLES | C3-ACYLATION | CHEMISTRY, ORGANIC | RECENT PROGRESS | BOND ACTIVATION | CATALYZED ACYLATION | CYCLIZATION
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 2015, Volume 13, Issue 11, pp. 3416 - 3431
A new class of pyrazole and isoxazole conjugates were synthesized and evaluated for their cytotoxic activity against various human cancer cell lines. These... 
COMBRETASTATIN A-4 ANALOGS | POTENT | COLCHICINE | ISOXAZOLE DERIVATIVES | 3-AROYLINDOLES | DRUGS | BIOLOGICAL EVALUATION | CHEMISTRY, ORGANIC | ANTITUMOR-ACTIVITY | BINDING | CANCER
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 2017, Volume 15, Issue 32, pp. 6702 - 6705
An efficient one-pot method was developed for the construction of 3-acylindoles via oxidative rearrangement of 2-aminochalcones followed by intramolecular... 
FRIEDEL-CRAFTS ACYLATION | PHENYLIODINE(III) BIS(TRIFLUOROACETATE) PIFA | ROUTE | N-H INDOLES | BIS(INDOLE) ALKALOIDS | ONE-POT | 3-AROYLINDOLES | C3-ACYLATION | CHEMISTRY | CHEMISTRY, ORGANIC | CATALYZED ACYLATION
Journal Article
Organic & biomolecular chemistry, ISSN 1477-0520, 08/2017, Volume 15, Issue 32, pp. 6702 - 6705
An efficient one-pot method was developed for the construction of 3-acylindoles via oxidative rearrangement of 2-aminochalcones followed by intramolecular... 
Journal Article
by Li, YN and Wang, B and Xing, RG
HETEROCYCLES, ISSN 0385-5414, 02/2019, Volume 98, Issue 2, pp. 295 - 303
An efficient reductive cyclization of o-nitrobenzyl ketone compounds was achieved by using a Hantzsch 1,4-dihydropyridine ester as a biomimetic reducing agent... 
FUNCTIONALIZATION | ASSISTED INTRAMOLECULAR AMINATION | REDUCTION | 1,4-DIHYDROPYRIDINE | ANALOGS | 3-AROYLINDOLES | CHEMISTRY, ORGANIC | OLEFINS | ADDITIONS | EFFICIENT | PD/C
Journal Article
by Zhang, ZB and Yang, YS and Yu, ZX and Xia, JB
ACS catalysis, ISSN 2155-5435, 05/2020, Volume 10, Issue 10, pp. 5419 - 5429
Lewis base-catalyzed transformations of allenes have received much attention over the last decades. However, this type of reaction has so far been limited to... 
DOMINO REACTION | ACTIVATION | CHEMISTRY, PHYSICAL | proton transfer | ACYL | ALLENES | ALKYNES | Lewis base catalysis | 3+2 CYCLOADDITION | ACYCLIC AMIDES | 4+2 ANNULATION | C-N bond cleavage | 3-aroylindoles | CARBON-NITROGEN BOND | weakly activated allenes
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 12/2014, Volume 55, Issue 52, pp. 7198 - 7202
Journal Article
European Journal of Organic Chemistry, ISSN 1434-193X, 03/2016, Volume 2016, Issue 7, pp. 1449 - 1453
A Cu‐catalyzed synthesis of indoloquinoxalin‐6‐one has been developed that starts from o‐indolyl‐N,N‐dialkylamines through sp3 C–H bond oxidation α to the... 
C–H activation | Synthetic methods | Nitrogen heterocycles | Copper | Cross‐coupling | Homogeneous catalysis | C-H activation | Cross-coupling | CATALYSIS | SP C-H | PHOTOREDOX | TERTIARY-AMINES | STRATEGY | CHEMISTRY, ORGANIC | ADJACENT | 3-AROYLINDOLES | NITROGEN | BOND ACTIVATION | MOLECULAR-OXYGEN
Journal Article
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