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PloS one, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, p. e60581
Most conditions detected by expanded newborn screening result from deficiency of one of the enzymes that degrade acyl-coenzyme A (CoA... 
RAT-LIVER | 3-HYDROXY-3-METHYLGLUTARYL-COA LYASE | INHIBITION | METABOLISM | COENZYME-A PROFILES | PYRUVATE-CARBOXYLASE | QUANTIFICATION | MULTIDISCIPLINARY SCIENCES | DEFICIENT MICE | LYASE HL | SPECTROMETRY | Hyperammonemia - metabolism | Humans | Hypoglycemia - mortality | Acetyl Coenzyme A - genetics | Acyl Coenzyme A - genetics | Hepatocytes - metabolism | Mitochondria - ultrastructure | Genes, Lethal | Mitochondria - genetics | Pyruvic Acid - metabolism | Hyperammonemia - mortality | Gene Order | Hypoglycemia - genetics | Gene Targeting | Hyperammonemia - genetics | Leucine - metabolism | Carbon Dioxide - metabolism | Liver - metabolism | Acyl Coenzyme A - deficiency | Metabolome | Mitochondria - metabolism | Gene Knockout Techniques | Hypoglycemia - metabolism | Acetyl Coenzyme A - metabolism | Mice, Knockout | Peroxisomes | Phenotype | Animals | Gluconeogenesis - genetics | Metabolic Networks and Pathways | Models, Biological | Lethargy | Mice | Enzymes | Esters | Metabolites | Glutamate | Analysis | Organic acids | Glutamic acid | Inborn errors of metabolism | Ketogenesis | Laboratories | Liver | Pyruvic acid | Leucine | Defects | Degradation | Proteins | Mitochondria | Rodents | Coenzyme A | Chemical synthesis | Gluconeogenesis | Urine | Medical research | Incubation | Hyperammonemia | Hypoglycemia | Metabolism | Fatty acids | Studies | Urea | Hepatocytes | Carboxylation | Scientific imaging | Mass spectrometry | Acetyl Coenzyme A | Life Sciences | Hépatology and Gastroenterology | Carbon Dioxide | Human health and pathology | Pyruvic Acid | Acyl Coenzyme A
Journal Article
Rheumatology (Oxford, England), ISSN 1462-0324, 2017, Volume 56, Issue 2, pp. 287 - 293
Journal Article
Journal of the American Heart Association, ISSN 2047-9980, 02/2016, Volume 5, Issue 2, p. n/a
.... In vitro, activator protein 1 activity was inhibited by two 3‐hydroxy‐3‐methylglutaryl coenzyme A reductase inhibitors, rosuvastatin and atorvastatin, in stretch... 
smooth muscle cells | veins | activator protein 1 | 3‐hydroxy‐3‐methylglutaryl coenzyme A reductase inhibitors | vascular remodeling | Vascular remodeling | Veins | Smooth muscle cells | 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors | Activator protein 1 | CARDIAC & CARDIOVASCULAR SYSTEMS | VIVO | CHRONIC VENOUS INSUFFICIENCY | PROLIFERATION | RANDOMIZED CONTROLLED-TRIAL | DECOY OLIGODEOXYNUCLEOTIDES | IN-VITRO | MATRIX-METALLOPROTEINASE-9 | SMOOTH-MUSCLE-CELLS | ACTIVATOR PROTEIN-1 | EXPRESSION | Muscle, Smooth, Vascular - metabolism | Transcription Factor AP-1 - genetics | Humans | Middle Aged | Varicose Veins - prevention & control | Myocytes, Smooth Muscle - pathology | Male | Transcription Factor AP-1 - metabolism | Case-Control Studies | Dose-Response Relationship, Drug | Time Factors | Varicose Veins - metabolism | Female | Chemokine CCL2 - metabolism | Vascular Remodeling - drug effects | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | Disease Models, Animal | Muscle, Smooth, Vascular - drug effects | Rosuvastatin Calcium - pharmacology | Cells, Cultured | Varicose Veins - pathology | Atorvastatin - pharmacology | Veins - drug effects | Muscle, Smooth, Vascular - pathology | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Signal Transduction - drug effects | Veins - metabolism | Cell Proliferation - drug effects | Mice | Veins - pathology
Journal Article
Journal Article
Circulation research, ISSN 0009-7330, 02/2007, Volume 100, Issue 2, pp. e12 - e21
The rate-limiting enzyme for cholesterol synthesis, the hydroxy-methylglutaryl coenzyme A reductase (HCR... 
Shear stress | Signal transduction | HMG-CoA reductase | Nitric oxide | Endothelial cells | RAT-LIVER | endothelial cells | nitric oxide | CARDIAC & CARDIOVASCULAR SYSTEMS | ANGIOGENESIS | signal transduction | PHOSPHORYLATION | NITRIC-OXIDE SYNTHASE | AKT | 3-HYDROXY-3-METHYLGLUTARYL COENZYME | KNOCKOUT MICE | CROSS-TALK | shear stress | HYPERPOLARIZING FACTOR | PERIPHERAL VASCULAR DISEASE | INHIBITORS | HEMATOLOGY | Endothelium, Vascular - cytology | Humans | Molecular Sequence Data | Multienzyme Complexes - metabolism | Stress, Mechanical | Forkhead Transcription Factors - physiology | Endothelium, Vascular - enzymology | AMP-Activated Protein Kinases | Hydroxymethylglutaryl-CoA Reductase Inhibitors - metabolism | Hydroxymethylglutaryl CoA Reductases - metabolism | Swine | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Forkhead Transcription Factors - antagonists & inhibitors | Protein-Serine-Threonine Kinases - metabolism | Amino Acid Sequence | Shear Strength | Endothelial Cells - metabolism | Nitric Oxide - antagonists & inhibitors | Mice, Inbred C57BL | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Nitric Oxide - physiology | Multienzyme Complexes - genetics | Forkhead Transcription Factors - genetics | Multienzyme Complexes - antagonists & inhibitors | Mice, Knockout | Animals | Endothelium, Vascular - metabolism | Nitric Oxide - genetics | Forkhead Box Protein O1 | Mice | Endothelial Cells - enzymology | Enzyme Activation - physiology | Hydroxymethylglutaryl CoA Reductases - genetics
Journal Article
Journal Article
BMC molecular biology, ISSN 1471-2199, 09/2012, Volume 13, Issue 1, pp. 29 - 29
Journal Article