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The Journal of pharmacology and experimental therapeutics, ISSN 0022-3565, 12/2010, Volume 335, Issue 3, pp. 533 - 545
Journal Article
American Journal of Physiology - Endocrinology And Metabolism, ISSN 0193-1849, 02/2009, Volume 296, Issue 2, pp. 244 - 255
Journal Article
BMC cancer, ISSN 1471-2407, 08/2012, Volume 12, Issue 1, pp. 381 - 381
Background: Since proteins involved in chemotherapy drug pharmacokinetics and pharmacodynamics have a strong impact on the uptake, metabolism, and efflux of such drugs, they likely play critical roles... 
Resistance | Lysosome | Cytotoxicity | Drug localization | Aldo-keto reductases | Pharmacokinetics | Doxorubicin | DNA-binding | Gene profiling | PharmGKB | Life Sciences & Biomedicine | Oncology | Science & Technology | 3-Hydroxysteroid Dehydrogenases - biosynthesis | Aldehyde Reductase - genetics | Oligonucleotide Array Sequence Analysis | Cyclosporine - pharmacology | DNA, Neoplasm - metabolism | Humans | Drug Resistance, Neoplasm | Gene Expression Profiling | Hydroxyprostaglandin Dehydrogenases - metabolism | Breast Neoplasms - metabolism | Cell Nucleus - metabolism | MCF-7 Cells | Doxorubicin - analogs & derivatives | 3-Hydroxysteroid Dehydrogenases - metabolism | Aldehyde Reductase - metabolism | 20-Hydroxysteroid Dehydrogenases - biosynthesis | 20-Hydroxysteroid Dehydrogenases - genetics | Intracellular Space - drug effects | Aldehyde Reductase - biosynthesis | Hydroxyprostaglandin Dehydrogenases - biosynthesis | 20-Hydroxysteroid Dehydrogenases - metabolism | Breast Neoplasms - drug therapy | Doxorubicin - pharmacokinetics | Hydroxyprostaglandin Dehydrogenases - genetics | Cholic Acids - pharmacology | Breast Neoplasms - genetics | Aldo-Keto Reductase Family 1 Member C3 | Intracellular Space - metabolism | 3-Hydroxysteroid Dehydrogenases - genetics | Cell Nucleus - drug effects | Doxorubicin - pharmacology | Anthracyclines | Genes | Genomics | Genomes | Drug resistance | Proteins | Chemotherapy | Metabolites | Aldose reductase | Analysis | DNA | Genetic research | DNA-ligand interactions | Cancer | Index Medicus
Journal Article
Clinical cancer research, ISSN 1078-0432, 10/2013, Volume 19, Issue 20, pp. 5613 - 5625
Journal Article
Journal Article
Journal Article
Biochemical journal, ISSN 0264-6021, 12/2011, Volume 440, Issue 3, pp. 335 - 344
Journal Article
Toxicology and applied pharmacology, ISSN 0041-008X, 08/2014, Volume 278, Issue 3, pp. 238 - 248
Pharmacokinetic drug resistance is a serious obstacle that emerges during cancer chemotherapy. In this study, we investigated the possible role of aldo-keto... 
Anthracyclines | Aldo-keto reductase 1C3 | Drug resistance | Metabolism | Enzyme induction | Pharmacology & Pharmacy | Toxicology | Life Sciences & Biomedicine | Science & Technology | Antibiotics, Antineoplastic - pharmacology | Humans | Daunorubicin - agonists | Daunorubicin - pharmacology | Idarubicin - pharmacology | Neoplasm Proteins - antagonists & inhibitors | Neoplasm Proteins - metabolism | Anthracyclines - agonists | Hydroxyprostaglandin Dehydrogenases - metabolism | 3-Hydroxysteroid Dehydrogenases - antagonists & inhibitors | Anthracyclines - pharmacology | Biotransformation | Anthracyclines - metabolism | Enzyme Induction - drug effects | 3-Hydroxysteroid Dehydrogenases - metabolism | Doxorubicin - metabolism | Daunorubicin - metabolism | Neoplasm Proteins - genetics | Antibiotics, Antineoplastic - agonists | Carcinoma - drug therapy | Idarubicin - metabolism | Recombinant Proteins - metabolism | Cell Survival - drug effects | Oxidation-Reduction | Flavanones - pharmacology | Enzyme Inhibitors - pharmacology | Recombinant Proteins - chemistry | Hydroxyprostaglandin Dehydrogenases - genetics | Drug Synergism | Hydroxyprostaglandin Dehydrogenases - antagonists & inhibitors | Aldo-Keto Reductase Family 1 Member C3 | Cell Line, Tumor | Kinetics | 3-Hydroxysteroid Dehydrogenases - genetics | Antibiotics, Antineoplastic - metabolism | Idarubicin - agonists | Doxorubicin - pharmacology | Drug Resistance, Neoplasm - drug effects | Physiological aspects | Chemotherapy | Cancer cells | Cancer | Index Medicus | CARBONYLS | METABOLISM | NEOPLASMS | ENZYMES | DRUGS | TOXICITY | INCUBATION | 60 APPLIED LIFE SCIENCES | ENZYME INDUCTION | CHEMOTHERAPY
Journal Article
Cancer research (Chicago, Ill.), ISSN 0008-5472, 02/2010, Volume 70, Issue 3, pp. 1256 - 1264
Journal Article
PLoS biology, ISSN 1545-7885, 04/2012, Volume 10, Issue 4, pp. e1001305 - e1001305
Journal Article
Journal Article