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PloS one, ISSN 1932-6203, 2011, Volume 6, Issue 6, pp. e21402 - e21402
Androgens are important regulators of bone mass but the relative importance of testosterone (T) versus dihydrotestosterone (DHT) for the activation of the... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Bone and Bones - pathology | Bone Density - physiology | Forelimb - physiology | Receptors, Prolactin - blood | Body Weight - drug effects | Male | Gene Expression Profiling | RNA, Messenger - metabolism | Testosterone - pharmacology | Membrane Proteins - deficiency | Isoenzymes - metabolism | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - metabolism | Female | Ovary - drug effects | Membrane Proteins - metabolism | Forelimb - drug effects | Ovary - pathology | Viscera - metabolism | Isoenzymes - genetics | Membrane Proteins - genetics | RNA, Messenger - genetics | Receptors, Prolactin - genetics | Viscera - drug effects | Enzyme Activation - drug effects | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - deficiency | Mice, Knockout | Orchiectomy | Bone Density - drug effects | Bone and Bones - physiopathology | Organ Size - drug effects | Animals | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - genetics | Mice | Muscle Strength - drug effects | Androgens - metabolism | Body Weight - physiology | Hand Strength - physiology | Muscle Strength - physiology | Regulators | Liver | Estrogens | Arthritis | Insulin-like growth factors | Bone (trabecular) | Males | Dihydrotestosterone | Coding | Rodents | Animal tissues | Grip strength | Muscular strength | Bone (cortical) | Drug dosages | Polycystic ovary syndrome | Enzymes | Isoenzymes | Metabolism | Bone mineral content | Medicine | Testosterone | Androgens | Bone mass | Nitric oxide | Bone mineral density | Clinical medicine | Females | Prostate | Reductase | Index Medicus | Bone and Bones | Body Weight | pathology | RNA | Ovary | Receptors | genetics | Endokrinologi och diabetes | Prolactin | Viscera | pharmacology | Muscle Strength | Forelimb | Hand Strength | Endocrinology and Diabetes | Bone Density | physiology | Organ Size | drug effects | Messenger | blood | Knockout | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase | Membrane Proteins | physiopathology | deficiency | metabolism | Enzyme Activation | Estrogen
Journal Article
Cancer research (Chicago, Ill.), ISSN 0008-5472, 02/2010, Volume 70, Issue 3, pp. 1256 - 1264
Journal Article
Journal Article
Reproduction (Cambridge, England), ISSN 1470-1626, 2017, Volume 154, Issue 4, pp. 445 - 454
Equine fetuses have substantial circulating pregnenolone concentrations and thus have been postulated to provide significant substrate for placental 5... 
Life Sciences & Biomedicine | Developmental Biology | Reproductive Biology | Science & Technology | Dehydroepiandrosterone - biosynthesis | Cholesterol Side-Chain Cleavage Enzyme - metabolism | Testis - metabolism | Progesterone Reductase - metabolism | Gonadal Steroid Hormones - biosynthesis | Androstenedione - blood | Aromatase - metabolism | Multienzyme Complexes - metabolism | Male | Gonadal Steroid Hormones - blood | Adrenal Glands - embryology | Embryo, Mammalian - metabolism | Cholesterol Side-Chain Cleavage Enzyme - genetics | Aromatase - genetics | Adrenal Cortex Hormones - biosynthesis | Testis - embryology | Gene Expression Regulation, Developmental | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - metabolism | Female | Steroid Isomerases - genetics | Pregnenolone - biosynthesis | Ovary - metabolism | Ovary - embryology | Steroid Isomerases - metabolism | Placenta - embryology | Dehydroepiandrosterone - blood | Multienzyme Complexes - genetics | Progesterone Reductase - genetics | Gestational Age | Gene Expression Regulation, Enzymologic | Placenta - metabolism | Pregnancy | Animals | Pregnenolone - blood | Adrenal Glands - metabolism | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - genetics | Horses | Steroid 17-alpha-Hydroxylase - genetics | Steroid 17-alpha-Hydroxylase - metabolism | Adrenal Cortex Hormones - blood | Androstenedione - biosynthesis | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 9/2006, Volume 103, Issue 39, pp. 14602 - 14607
Allopregnanolone (ALLO) and tetrahydrodeoxycorticosterone (THDOC) are potent positive allosteric modulators of GABA action at receptors. ALLO and THDOC are... 
Brain | Enzymes | Receptors | Messenger RNA | Neurons | Purkinje cells | Pyramidal cells | Neuroglia | Antibodies | Hippocampus | Glutamatergic neurons | 5α-reductase (type I) | GABAergic neurons | 3α-hydroxysteroid dehydrogenase | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Brain - enzymology | Male | Neurons - cytology | Cerebellum - enzymology | RNA, Messenger - metabolism | Cerebral Cortex - cytology | Corpus Striatum - cytology | 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific) - genetics | Amygdala - enzymology | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - metabolism | Hippocampus - enzymology | Corpus Striatum - enzymology | Olfactory Bulb - cytology | Olfactory Bulb - enzymology | Cerebral Cortex - enzymology | RNA, Messenger - genetics | Thalamus - enzymology | Rats | Amygdala - cytology | Hippocampus - cytology | Desoxycorticosterone - analogs & derivatives | Desoxycorticosterone - biosynthesis | Gene Expression Regulation, Enzymologic | Membrane Proteins | Animals | Pregnanolone - biosynthesis | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - genetics | 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific) - metabolism | Neurons - enzymology | Cerebellum - cytology | Thalamus - cytology | Mice | GABA | Research | Progesterone | Oxidoreductases | Structure | Steroids | Proteins | Rodents | Cells | Index Medicus | Biological Sciences | glutamatergic neurons
Journal Article
PloS one, ISSN 1932-6203, 02/2013, Volume 8, Issue 2, pp. e55905 - e55905
The high incidence of prostate cancer (PCa) and benign prostatic hypertrophy (BPH) in elderly men is a cause of increasing public health concern. In recent... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Estradiol - blood | Rats, Wistar | Aromatase - metabolism | Male | Immunoenzyme Techniques | Prostate - metabolism | Aromatase - genetics | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - metabolism | Prostate - drug effects | Membrane Proteins - metabolism | Testosterone - blood | Prostatic Hyperplasia - drug therapy | Real-Time Polymerase Chain Reaction | Phenols - pharmacology | Isoenzymes | Membrane Proteins - genetics | RNA, Messenger - genetics | Rats | Reverse Transcriptase Polymerase Chain Reaction | Prostatic Hyperplasia - genetics | Blotting, Western | Prostatic Hyperplasia - metabolism | Animals | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - genetics | Benzhydryl Compounds - pharmacology | Estrogens, Non-Steroidal - pharmacology | Endocrine disruptors | Neurosciences | Estrogens | mRNA | Biochemistry | Biosynthesis | Malignancy | Estradiol | Proteins | Dihydrotestosterone | Rodents | Aromatase | Older people | Drug dosages | Public health | Enzymes | Health risks | Organs | Exposure | Gene expression | Medicine | Polymerase chain reaction | Bisphenol A | Sex hormones | Testosterone | Androgens | Phenols | Biomarkers | Laboratory animals | Molecular biology | Prostate cancer | Prostate | Hypertrophy | Geriatrics | Reductase | Index Medicus
Journal Article
Cancer research (Chicago, Ill.), ISSN 1538-7445, 12/2012, Volume 72, Issue 23, pp. 6142 - 6152
...), because of several mechanisms that include increased AR expression and intratumoral androgen metabolism... 
Life Sciences & Biomedicine | Oncology | Science & Technology | 3-Hydroxysteroid Dehydrogenases - biosynthesis | Immunohistochemistry | Neoplasms, Hormone-Dependent - metabolism | Prostatic Neoplasms - metabolism | Humans | Receptors, Androgen - metabolism | Gene Expression Regulation, Neoplastic | Transcriptome | Androgens - biosynthesis | Data Mining | Male | Hydroxyprostaglandin Dehydrogenases - metabolism | Neoplasms, Hormone-Dependent - genetics | RNA, Messenger - biosynthesis | Neoplasm Metastasis | Prostatic Neoplasms - genetics | Cytochrome P-450 CYP3A - genetics | Receptors, Androgen - biosynthesis | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - metabolism | 3-Hydroxysteroid Dehydrogenases - metabolism | Neoplasms, Hormone-Dependent - enzymology | Cytochrome P-450 CYP3A - biosynthesis | Prostatic Neoplasms - pathology | RNA, Messenger - genetics | Hydroxyprostaglandin Dehydrogenases - biosynthesis | Hydroxyprostaglandin Dehydrogenases - genetics | Orchiectomy | Gene Expression Regulation, Enzymologic | Receptors, Androgen - genetics | Aldo-Keto Reductase Family 1 Member C3 | Cytochrome P-450 CYP3A - metabolism | Neoplasms, Hormone-Dependent - pathology | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - genetics | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - biosynthesis | Cell Line, Tumor | Prostatic Neoplasms - enzymology | 3-Hydroxysteroid Dehydrogenases - genetics | Androgens - metabolism | Index Medicus | abiraterone | androgen synthesis | testosterone | dihydrotestosterone | AKR1C3 | CYP17 | MDV3100 (enzalutamide) | Prostate cancer
Journal Article