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3-phosphoglycerate kinase (255) 255
biochemistry & molecular biology (231) 231
index medicus (154) 154
humans (130) 130
animals (124) 124
3-phosphoglycerate (101) 101
3-phosphoglycerate dehydrogenase (101) 101
molecular sequence data (95) 95
enzymes (92) 92
phosphoglycerate kinase (92) 92
phosphoglycerate kinase - metabolism (89) 89
amino acid sequence (81) 81
kinetics (81) 81
phosphoglycerate kinase - chemistry (81) 81
plant sciences (78) 78
escherichia-coli (73) 73
phosphoglycerate kinase - genetics (72) 72
biophysics (71) 71
analysis (67) 67
3-phosphoglycerate dehydrogenase-deficiency (60) 60
serine (60) 60
biosynthesis (57) 57
metabolism (57) 57
enzyme (56) 56
expression (56) 56
glyceraldehyde-3-phosphate dehydrogenase (56) 56
physiological aspects (55) 55
protein conformation (55) 55
proteins (54) 54
sequence (53) 53
genetics & heredity (52) 52
research (52) 52
glycolysis (49) 49
male (49) 49
models, molecular (48) 48
base sequence (47) 47
cell biology (44) 44
site-directed mutagenesis (43) 43
saccharomyces cerevisiae - enzymology (42) 42
mutation (41) 41
phosphorylation (39) 39
mice (38) 38
amino acids (37) 37
cloning, molecular (37) 37
serine - metabolism (37) 37
phosphoglycerate dehydrogenase (36) 36
genetic aspects (34) 34
acetyl-coa carboxylase (33) 33
genes (33) 33
l-serine (33) 33
life sciences (33) 33
microbiology (32) 32
phosphates (32) 32
phylogeny (32) 32
gene expression (31) 31
binding sites (30) 30
female (30) 30
gene (30) 30
protein structure, tertiary (30) 30
substrate specificity (30) 30
catalysis (29) 29
sequence homology, amino acid (29) 29
biochemistry, general (28) 28
plants (28) 28
serine - biosynthesis (28) 28
protein (27) 27
research article (27) 27
wheat (27) 27
binding (26) 26
photosynthesis (26) 26
protein folding (26) 26
cloning (25) 25
glycine (25) 25
neurosciences (25) 25
protein binding (25) 25
biotechnology & applied microbiology (24) 24
escherichia coli - genetics (24) 24
glyceric acids - metabolism (24) 24
mutagenesis, site-directed (24) 24
phosphoglycerate dehydrogenase - metabolism (24) 24
rats (24) 24
protein denaturation (23) 23
purification (23) 23
serine biosynthesis (23) 23
infant (22) 22
mechanism (22) 22
article (21) 21
glucose (21) 21
inhibition (21) 21
phosphoglycerate dehydrogenase - genetics (21) 21
saccharomyces-cerevisiae (21) 21
yeast phosphoglycerate kinase (21) 21
brain (20) 20
escherichia coli (20) 20
evolution (20) 20
glyceraldehyde-3-phosphate dehydrogenases - metabolism (20) 20
pediatrics (20) 20
adenosine triphosphate - metabolism (19) 19
clinical neurology (19) 19
complex (19) 19
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Nature Reviews Cancer, ISSN 1474-175X, 09/2016, Volume 16, Issue 10, pp. 650 - 662
Journal Article
Nature Genetics, ISSN 1061-4036, 09/2011, Volume 43, Issue 9, pp. 869 - 874
Journal Article
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 09/2019, Volume 62, Issue 17, pp. 7976 - 7997
Phosphoglycerate dehydrogenase (PHGDH) is known to be the rate-limiting enzyme in the serine synthesis pathway in humans. It converts glycolysis-derived... 
3-PHOSPHOGLYCERATE DEHYDROGENASE | DESIGN | CHEMISTRY, MEDICINAL | LIGAND-BINDING | METABOLISM | PATHWAY | IDH1 | ALLYLIC 1,3-STRAIN | CONTRIBUTES | EXPRESSION | NEGATIVE BREAST-CANCER
Journal Article
Journal of Shanghai Jiaotong University (Medical Science), ISSN 1674-8115, 04/2018, Volume 38, Issue 4, pp. 463 - 466
Journal Article
Journal of Cell Biology, ISSN 0021-9525, 08/2016, Volume 214, Issue 3, pp. 249 - 257
Journal Article
The Plant Cell, ISSN 1040-4651, 4/2011, Volume 23, Issue 4, pp. 1249 - 1263
Journal Article
BIOCHEMISTRY, ISSN 0006-2960, 03/2018, Volume 57, Issue 11, pp. 1798 - 1806
The equilibrium of the reaction catalyzed by D-3-phosphoglycerate dehydrogenase (PGDH), the first enzyme in the L-serine biosynthetic pathway, is far in the... 
MYCOBACTERIUM-TUBERCULOSIS | 3-PHOSPHOGLYCERATE DEHYDROGENASE | ANIMAL-TISSUES | PHOSPHOGLYCERATE DEHYDROGENASE | HIGHER-PLANTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | TUBERCULOSIS D-3-PHOSPHOGLYCERATE DEHYDROGENASE | D-2-HYDROXYGLUTARATE | END PRODUCT INHIBITION | EFFECTOR-BINDING
Journal Article