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4,4′-diisothiocyanatostilbene-2,2′-disulfonic acid (10) 10
animals (9) 9
biochemistry & molecular biology (8) 8
4,4'-diisothiocyanostilbene-2,2'-disulfonic acid - pharmacology (7) 7
4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid (6) 6
biophysics (6) 6
dids (6) 6
cell biology (5) 5
humans (5) 5
4,4 '-diisothiocyanatostilbene-2,2 '-disulfonic acid (4) 4
apoptosis (4) 4
chloride channels - antagonists & inhibitors (4) 4
hydrogen-ion concentration (4) 4
ion channels (4) 4
mice (4) 4
anion transport (3) 3
cell line (3) 3
cells, cultured (3) 3
chloride channel (3) 3
cystic fibrosis (3) 3
dose-response relationship, drug (3) 3
index medicus (3) 3
kinetics (3) 3
male (3) 3
membrane (3) 3
nitric oxide (3) 3
patch-clamp techniques (3) 3
physiology (3) 3
rats (3) 3
4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid inhibition (2) 2
4,4'-diisothiocyanostilbene-2,2'-disulfonic acid - metabolism (2) 2
4-acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid - pharmacology (2) 2
anions (2) 2
apoptosis - drug effects (2) 2
apoptosis - physiology (2) 2
band-3 (2) 2
bicarbonate transporter (2) 2
biological sciences (2) 2
biological transport (2) 2
brain (2) 2
cardiac & cardiovascular systems (2) 2
cells (2) 2
channel (2) 2
chloride channels (2) 2
chloride channels - metabolism (2) 2
chlorides - metabolism (2) 2
cl (2) 2
cl − channel (2) 2
cl- channel (2) 2
dids, 4,4′-diisothiocyanatostilbene-2,2′-disulfonic acid (2) 2
enzyme inhibitors - pharmacology (2) 2
epithelial secretion (2) 2
erythrocyte membrane - metabolism (2) 2
expression (2) 2
female (2) 2
hemoglobin (2) 2
inhibition (2) 2
ion channels - drug effects (2) 2
kidney (2) 2
mechanism (2) 2
membrane potentials (2) 2
membrane potentials - drug effects (2) 2
myocytes (2) 2
neurons - drug effects (2) 2
neurosciences (2) 2
niflumic acid (2) 2
niflumic acid - pharmacology (2) 2
nitrates - metabolism (2) 2
nitric-oxide (2) 2
oxidants - metabolism (2) 2
oxidation-reduction (2) 2
oxidative stress (2) 2
patch clamp (2) 2
pbs (2) 2
permeability (2) 2
pharmacology & pharmacy (2) 2
physiological aspects (2) 2
plant sciences (2) 2
plasmodium-falciparum (2) 2
potassium channel blockers - pharmacology (2) 2
protein (2) 2
proteins (2) 2
smooth-muscle cells (2) 2
superoxide (2) 2
v-atpase (2) 2
vesicles (2) 2
1,3-bis-1-nitrosourea (1) 1
2 '-disulfonic acid (1) 1
2′,7′-bis-5-carboxy-fluorescein-tetraacetoxymethyl ester (1) 1
2′-disulfonic acid (1) 1
2′‐disulfonic acid (1) 1
3t3 cells (1) 1
4,4 '-diisothiocyanatostilbene-2,2'-disulfonic acid (1) 1
4,4' -diisothiocyanatostilbene-2,2' disulfonic acid (1) 1
4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid dids (1) 1
4,4'-diisothiocyanostilbene-2,2'-disulfonic acid (1) 1
4,4′-diisothiocyanatostilbene-2, 2′-disulfonic acid (1) 1
4,4′-diisothiocyanatostilbene-2,2′disulfonic acid (1) 1
4-acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid - analogs & derivatives (1) 1
4-aminopyridine (1) 1
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Journal Article
Journal Article
Biochemistry (Washington), ISSN 0006-2960, 01/1991, Volume 30, Issue 23, pp. 5700 - 5706
Calcium accumulation by purified vesicles derived from basolateral membranes of kidney proximal tubules was reversibly inhibited by micromolar concentrations... 
kidney | plasma membranes | proximal tubules | 4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/1998, Volume 95, Issue 7, pp. 3566 - 3571
Journal Article
International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 05/2000, Volume 32, Issue 5, pp. 519 - 527
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/1998, Volume 95, Issue 7, pp. 3566 - 3571
Journal Article
Journal Article
Toxicology, ISSN 0300-483X, 2001, Volume 169, Issue 1, pp. 17 - 23
Suramin, a polysulfonated naphthylamine, caused a dose dependent inhibition of carbonyl cyanide p-(tri-fluoromethoxy)phenylhydrazone-stimulated respiration... 
Suramin | Thiol oxidation | Isolated rat liver mitochondria | Mitochondrial membrane permeability transition | Ca 2 | CARCINOMA-CELLS | OXIDATIVE STRESS | MECHANISM | suramin | CA2+ IONS | INORGANIC-PHOSPHATE | thiol oxidation | PLUS PROOXIDANTS | CYCLOSPORINE-A | DISRUPTION | 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID DIDS | Ca2 | mitochondrial membrane permeability transition | PHARMACOLOGY & PHARMACY | TOXICOLOGY | isolated rat liver mitochondria | THIOL CROSS-LINKING | Intracellular Membranes - physiology | Mitochondrial Swelling - drug effects | Rats, Wistar | Suramin - toxicity | Cyclosporine - pharmacology | Mitochondria, Liver - metabolism | Trypanocidal Agents - toxicity | Drug Interactions | Cell Respiration - drug effects | Ethylmaleimide - pharmacology | Membrane Potentials - drug effects | Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Rats | Chelating Agents - pharmacology | Magnesium - pharmacology | Adenosine Diphosphate - pharmacology | Mitochondria, Liver - drug effects | Animals | Egtazic Acid - pharmacology | Oxygen Consumption - drug effects | Cell Membrane Permeability - drug effects | Sulfhydryl Reagents - pharmacology | Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone - pharmacology | Intracellular Membranes - drug effects
Journal Article
Brain Research, ISSN 0006-8993, 2002, Volume 943, Issue 2, pp. 245 - 256
Cellular volume loss or shrinkage is a ubiquitous feature of apoptosis and thus may contribute to this form of degeneration. Chloride (Cl ) and potassium (K )... 
2′-Disulfonic acid | Exchanger | SITS (4-acetamido-4′-isothiocyanatostilbene-2 | K + channel | Cl − channel | DIDS (4,4′-diisothiocyanatostilbene-2,2′-disulfonic acid) | Transporter | channel | ACTIVATION | COTRANSPORT | SITS (4-acetamido-4 '-isothiocyanatostilbene-2 | MEMBRANE | Cl- channel | NEUROSCIENCES | CULTURED CORTICAL-NEURONS | OUTWARD POTASSIUM CURRENT | K+ channel | 2 '-disulfonic acid | DIDS (4,4 '-diisothiocyanatostilbene-2,2 '-disulfonic acid) | SHRINKAGE | PHARMACOLOGY | transporter | exchanger | ENHANCEMENT | THYMOCYTE APOPTOSIS | Neurons - pathology | Central Nervous System - metabolism | Sodium Potassium Chloride Symporter Inhibitors | Apoptosis - drug effects | Central Nervous System - pathology | Ion Channels - drug effects | Neuroblastoma | Neurodegenerative Diseases - drug therapy | Sodium-Potassium-Chloride Symporters - metabolism | Potassium Channels - metabolism | Potassium Chloride - pharmacology | Niflumic Acid - pharmacology | Cell Membrane - metabolism | Neurons - metabolism | Tumor Cells, Cultured | Neurons - drug effects | Cell Membrane - drug effects | Potassium Channel Blockers - pharmacology | Chloride Channels - antagonists & inhibitors | 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid - pharmacology | Cell Size - drug effects | Enzyme Inhibitors - pharmacology | Cell Size - physiology | Neurodegenerative Diseases - metabolism | Potassium Channels - drug effects | Bumetanide - pharmacology | Chloride Channels - metabolism | Animals | Neurodegenerative Diseases - physiopathology | Ion Channels - metabolism | 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid - pharmacology | Mice | Apoptosis - physiology | Central Nervous System - physiopathology | Furosemide - pharmacology | Staurosporine - pharmacology
Journal Article
FEBS Letters, ISSN 0014-5793, 2008, Volume 582, Issue 25, pp. 3601 - 3606
Journal Article
Journal Article