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Molecular Vision, ISSN 1090-0535, 01/2012, Volume 18, pp. 103 - 113
Purpose: To explore the ability of macrophages and microglial cells to phagocytize rod outer segments (ROSs) in a cell culture and characterize the resulting... 
4-Hydroxynonenal
Journal Article
PLoS ONE, 05/2013, Volume 8, Issue 5
The interplay of specific leukocyte subpopulations, resident cells and proalgesic mediators results in pain in inflammation. Proalgesic mediators like reactive... 
4-Hydroxynonenal
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 05/2003, Volume 85, Issue 4, pp. 999 - 1005
Reactive oxygen species are a necessary triggering event for apoptosis of sympathetic neurons after nerve growth factor (NGF) withdrawal. Reactive oxygen... 
4-Hydroxynonenal
Journal Article
Experimental Brain Research, ISSN 0014-4819, 03/2001, Volume 137, Issue 2, pp. 205 - 213
Lipid peroxidation is known to be associated with many neurodegenerative diseases and with traumatic brain injury, but its occurrence in the normal developing... 
4-Hydroxynonenal
Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 11/2000, Volume 57, Issue 12, pp. 1802 - 1809
The amyloid beta -peptide (A beta ) is a 4-kDa species derived from the amyloid precursor protein, which accumulates in the brains of patients with Alzheimer's... 
4-Hydroxynonenal
Journal Article
Microscopy Research and Technique, ISSN 1059-910X, 03/2001, Volume 52, Issue 6, pp. 709 - 718
Oligodendroglial reactions to compression injury of spinal cord include apoptosis, secondary demyelination, and remyelination failure. Within hours after... 
4-Hydroxynonenal
Journal Article
Neuroscience Letters, ISSN 0304-3940, 12/1999, Volume 277, Issue 2, pp. 91 - 94
Previous experiments reported that an incubation of striatal synaptosomes with 4-hydroxynonenal (4-HNE) resulted in an inhibition of dopamine (DA) uptake and... 
4-Hydroxynonenal
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 01/2008, Volume 153, Issue 1, pp. 6 - 20
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 2006, Volume 40, Issue 3, pp. 376 - 387
Ischemic stroke is caused by obstruction of blood flow to the brain, resulting in energy failure that initiates a complex series of metabolic events,... 
Oxidative stress | Stroke | Free radicals | CNS injury | Phosphatidylcholine | Cytidine-5′-diphosphocholine | Arachidonic acid | 4-hydroxynonenal
Journal Article
Biochemical Journal, ISSN 0264-6021, 05/2013, Volume 451, Issue 3, pp. 375 - 388
Vascular injury and chronic arterial diseases result in exposure of VSMCs (vascular smooth muscle cells) to increased concentrations of growth factors. The... 
Restenosis | 4-hydroxy-nonenal (4-HNE) | Spautin | Autophagy | Atherosclerosis | Growth factor | atherosclerosis | ALPHA-ACTIN | 4-hydroxynonenal (4-HNE) | restenosis | autophagy | ATHEROSCLEROTIC PLAQUES | LIPID-PEROXIDATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ISOLATED RAT HEPATOCYTES | growth factor | spautin | GROWTH-FACTOR RECEPTOR | INTIMAL HYPERPLASIA | PROTECTIVE ROLE | SERUM RESPONSE FACTOR | OXIDIZED PHOSPHOLIPIDS | DIFFERENTIATION MARKERS | Osteopontin - genetics | Microtubule-Associated Proteins - genetics | Muscle, Smooth, Vascular - metabolism | Oxidative Stress | Microtubule-Associated Proteins - metabolism | Vimentin - metabolism | Actins - metabolism | Male | Osteopontin - metabolism | Aorta - metabolism | Autophagy - drug effects | Actins - genetics | Vimentin - genetics | Aldehydes - pharmacology | Macrolides - pharmacology | Microfilament Proteins - metabolism | Autophagy - genetics | Myocytes, Smooth Muscle - drug effects | Microfilament Proteins - genetics | Myocytes, Smooth Muscle - cytology | Myocytes, Smooth Muscle - metabolism | Muscle, Smooth, Vascular - drug effects | Biomarkers - metabolism | Calcium-Binding Proteins - metabolism | Adenine - analogs & derivatives | Aorta - drug effects | Rats | Adenine - pharmacology | Platelet-Derived Growth Factor - pharmacology | Muscle, Smooth, Vascular - cytology | Rats, Sprague-Dawley | Gene Expression Regulation - drug effects | Phenotype | Animals | Signal Transduction - drug effects | Aorta - cytology | Primary Cell Culture | Calcium-Binding Proteins - genetics | 4-hydroxynonenal
Journal Article
Biology of Reproduction, ISSN 0006-3363, 2015, Volume 92, Issue 4
ABSTRACT Lipid peroxidation products such as the naturally occurring aldehyde 4-hydroxynonenal (4-HNE) are known to be cytotoxic toward different cell types,... 
methyltransferase | proteomics | epigenetics | protein kinase | 4-hydroxynonenal
Journal Article
Journal Article
Brain, ISSN 0006-8950, 05/2016, Volume 139, Issue 5, pp. 1361 - 1377
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 11/2019
Journal Article
BBA - General Subjects, ISSN 0304-4165, 03/2020, Volume 1864, Issue 3, p. 129487
Background: Skeletal muscle cells continuously generate reactive oxygen species (ROS). Excessive ROS can affect lipids resulting in lipid peroxidation (LPO).... 
Lipid peroxidation | Mitochondrial metabolism | Reactive oxygen species | Calcium oscillations | NADH | 4-hydroxynonenal
Journal Article