X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (468) 468
Publication (78) 78
Book Review (35) 35
Dissertation (4) 4
Book Chapter (3) 3
Conference Proceeding (2) 2
Government Document (2) 2
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
4e-bp1 (372) 372
index medicus (358) 358
phosphorylation (262) 262
humans (214) 214
animals (196) 196
phosphoproteins - metabolism (170) 170
mtor (159) 159
biochemistry & molecular biology (146) 146
cell biology (127) 127
translation (107) 107
mammalian target (102) 102
rapamycin (102) 102
male (100) 100
signal transduction (95) 95
adaptor proteins, signal transducing - metabolism (93) 93
protein biosynthesis (92) 92
proteins (89) 89
translation initiation (85) 85
mice (84) 84
oncology (77) 77
cancer (74) 74
tor serine-threonine kinases - metabolism (74) 74
eif4e (73) 73
protein binding (73) 73
activation (72) 72
carrier proteins - metabolism (72) 72
rats (72) 72
cell line, tumor (65) 65
female (63) 63
tor serine-threonine kinases (61) 61
sirolimus - pharmacology (60) 60
expression (59) 59
insulin (57) 57
akt (56) 56
phosphoproteins - genetics (56) 56
eukaryotic initiation factor-4e - metabolism (54) 54
protein-synthesis (53) 53
s6k1 (53) 53
cell line (51) 51
initiation (51) 51
growth (50) 50
p70 s6 kinase (47) 47
protein synthesis (47) 47
phas-i (43) 43
signal transduction - drug effects (43) 43
messenger-rna translation (42) 42
ribosomal protein s6 kinases, 70-kda - metabolism (41) 41
analysis (40) 40
messenger-rna (40) 40
adaptor proteins, signal transducing - genetics (39) 39
kinases (39) 39
pathway (38) 38
mechanistic target of rapamycin complex 1 (37) 37
phosphorylation - drug effects (36) 36
article (35) 35
genetic translation (35) 35
research (35) 35
adaptor proteins, signal transducing (34) 34
apoptosis (34) 34
biophysics (34) 34
peptide initiation factors - metabolism (34) 34
protein kinases - metabolism (34) 34
immunohistochemistry (33) 33
gene expression (32) 32
inhibition (32) 32
cell-growth (31) 31
eukaryotic initiation factor-4e (31) 31
middle aged (31) 31
cap-dependent translation (30) 30
cells (30) 30
kinase (30) 30
signaling pathway (30) 30
adult (29) 29
mtorc1 (29) 29
physiological aspects (29) 29
survival (29) 29
binding (28) 28
biological phenomena, cell phenomena, and immunity (28) 28
cells, cultured (28) 28
environment and public health (28) 28
muscle, skeletal - metabolism (28) 28
proto-oncogene proteins c-akt - metabolism (28) 28
breast-cancer (27) 27
initiation-factor 4e (27) 27
ribosomal protein s6 kinases - metabolism (27) 27
4e-binding protein-1 (26) 26
4e-bp1 phosphorylation (26) 26
protein biosynthesis - drug effects (26) 26
4e‐bp1 (25) 25
aged (25) 25
phosphatidylinositol 3-kinases - metabolism (25) 25
physiology (25) 25
prognosis (25) 25
rats, sprague-dawley (25) 25
skeletal-muscle (25) 25
cell cycle (24) 24
leucine (24) 24
multiprotein complexes - metabolism (24) 24
p70s6k (24) 24
rna, messenger - metabolism (24) 24
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 06/2009, Volume 106, Issue 26, pp. 10666 - 10671
The incidence of brain metastasis is rising and poses a severe clinical problem, as we lack effective therapies and knowledge of mechanisms that control... 
Angiogenesis | Integrin activation | 4E-BP1 | Brain metastasis | Biological Sciences | brain metastasis | integrin activation | angiogenesis
Journal Article
Cellular Signalling, ISSN 0898-6568, 05/2016, Volume 28, Issue 5, pp. 412 - 424
Iron is an indispensable micronutrient that regulates many aspects of cell function, including growth and proliferation. These processes are critically... 
Rheb | TSC2 | 4E-BP1 | PP2A | Akt | Deferoxamine | S6K1
Journal Article
Oncotarget, ISSN 1949-2553, 06/2019, Volume 10, Issue 40, pp. 4038 - 4052
Epithelioid glioblastoma is a recognized glioblastoma variant, recently added to the World Health Organization brain tumor classification, with similar... 
Journal Article
Cancer Gene Therapy, ISSN 0929-1903, 06/2013, Volume 20, Issue 6, pp. 331 - 335
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 05/2019, Volume 79, Issue 10, pp. 2480 - 2493
Reprogrammed glucose metabolism of enhanced aerobic glycolysis (or the Warburg effect) is known as a hallmark of cancer. The roles of long noncoding RNAs... 
GLYCOLYSIS | METASTASIS | ONCOLOGY | SPLICING FACTOR SF2/ASF | PHOSPHORYLATION | PATHWAY EFFECTOR TCF7L2 | 4E-BP1 | ENERGY-METABOLISM | EXPRESSION | PROMOTES | PROGRESSION
Journal Article
MOLECULAR CELL, ISSN 1097-2765, 06/2012, Volume 46, Issue 6, pp. 847 - 858
Translational control of gene expression plays a key role in many biological processes. Consequently, the activity of the translation apparatus is under tight... 
SIGNALING PATHWAY | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEGRADATION | INITIATION-FACTOR 4E | INHIBITOR 4E-BP1 | UBIQUITIN LIGASES | EIF4E | EXPRESSION | CANCER | PROGRESSION | CELL BIOLOGY
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2009, Volume 284, Issue 12, pp. 8023 - 8032
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 06/2009, Volume 106, Issue 26, pp. 10666 - 10671
The incidence of brain metastasis is rising and poses a severe clinical problem, as we lack effective therapies and knowledge of mechanisms that control... 
CARCINOMA-CELLS | integrin activation | angiogenesis | MULTIDISCIPLINARY SCIENCES | PROLIFERATION | MALIGNANT-MELANOMA | TRANSLATION | BREAST-CANCER | ADHESION | MICROENVIRONMENT | PLATELETS | brain metastasis | 4E-BP1 | EXPRESSION | PROGRESSION
Journal Article
Cellular Signalling, ISSN 0898-6568, 10/2019, Volume 62, pp. 109331 - 109331
Upon occurrence of kidney injury, tubular cells arrested in G2/M stage may promote interstitial fibroblast activation and kidney fibrosis through producing... 
4E-BP1 | Kidney fibrosis | G2/M arrest | mTORC1 | Tubular epithelial cells | CYCLE ARREST | PROLIFERATION | MESENCHYMAL TRANSITION | MTOR | P53 | CELL BIOLOGY | FIBROBLAST ACTIVATION | GROWTH | MITOTIC CHECKPOINT | Index Medicus
Journal Article
Oncogene, ISSN 0950-9232, 1/2016, Volume 35, Issue 2, pp. 148 - 157
The mammalian target of rapamycin (mTOR) is commonly activated in colon cancer. mTOR complex 1 (mTORC1) is a major downstream target of the PI3K/ATK pathway... 
mTOR inhibitors | ER stress | apoptosis | 4E-BP1 | FADD | DR5
Journal Article
Science translational medicine, ISSN 1946-6234, 07/2019, Volume 11, Issue 503, p. eaaw4993
The androgen receptor (AR) is a driver of cellular differentiation and prostate cancer development. An extensive body of work has linked these normal and... 
MEDICINE, RESEARCH & EXPERIMENTAL | INITIATION | PHOSPHORYLATION | INSULIN-RESISTANCE | CELL-PROLIFERATION | 4E-BP1 | DIET-INDUCED OBESITY | PROTEIN-SYNTHESIS | EIF4E | TUMORIGENESIS | SMALL-MOLECULE INHIBITION | CELL BIOLOGY | Index Medicus
Journal Article
GENES & DEVELOPMENT, ISSN 0890-9369, 06/2003, Volume 17, Issue 11, pp. 1352 - 1365
To elucidate the functions of the serine/threonine kinase Akt/PKB in vivo, we generated mice lacking both akt1 and akt2 genes. Akt1/Akt2 double-knockout (DKO)... 
C/EBP | S6K | TSC2 | DEVELOPMENTAL BIOLOGY | CELL-GROWTH | FKHR/FOXO | SIGNALING PATHWAY | CLONAL EXPANSION | IN-VIVO | GENETICS & HEREDITY | mTOR | KINASE-B-GAMMA | PPAR-GAMMA | ADIPOCYTE DIFFERENTIATION | TUMOR-SUPPRESSOR | 4E-BP1 | INSULIN-RECEPTOR SUBSTRATE-1 | TRANSGENIC MICE
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 2016, Volume 310, Issue 11, p. C874
Protein synthesis is stimulated by resistance exercise and intake of amino acids, in particular leucine. Moreover, activation of mammalian target of rapamycin... 
Medical and Health Sciences | Medicin och hälsovetenskap | 4E-BP1 | BCAA | Skeletal muscle | S6K1
Journal Article
GENES & DEVELOPMENT, ISSN 0890-9369, 04/2019, Volume 33, Issue 7-8, pp. 418 - 435
The RNA polymerase II (RNAPII) C-terminal domain kinase, CDK12, regulates genome stability, expression of DNA repair genes, and cancer cell resistance to... 
genome stability | DNA-DAMAGE | KINASE | TRANSCRIPTION ELONGATION | DEVELOPMENTAL BIOLOGY | PROTEIN-SYNTHESIS | CELL BIOLOGY | POLYMERASE-II CTD | RNAPII CTD kinase | MESSENGER-RNA | chromosome misalignment | GENETICS & HEREDITY | translation | SYNTHETIC LETHALITY | 4E-BP1 | CDK12 | C-TERMINAL DOMAIN | MUTATIONS | mTORC1 | EXPRESSION | Index Medicus
Journal Article
MOLECULAR CARCINOGENESIS, ISSN 0899-1987, 09/2019, Volume 58, Issue 9, pp. 1680 - 1690
Treatment with vemurafenib, a potent and selective inhibitor of mitogen-activated protein kinase signaling downstream of the BRAF(V600E) oncogene, elicits... 
APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PTEN | BRAF | INDUCTION | BRAFV600E | ONCOLOGY | metastatic melanoma | vemurafenib resistance | GROWTH | 4E-BP1 | metabolic reprogramming | PROGRESSION
Journal Article
by Kuo, CT and Chen, CL and Li, CC and Huang, GS and Ma, WY and Hsu, WF and Lin, CH and Lu, YS and Wo, AM
SCIENTIFIC REPORTS, ISSN 2045-2322, 07/2019, Volume 9, Issue 1, pp. 10898 - 11
When breast cancer patients start to exhibit resistance to hormonal therapy or chemotherapy, the mTOR inhibitor everolimus can be considered as an alternative... 
INDUCED ACTIVATION | PIK3CA | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | SENSITIVITY | PTEN | 4E-BP1 | CELL-GROWTH | MESENCHYMAL TRANSITION | TOR protein | Cell culture | LKB1 protein | Chemotherapy | Extracellular signal-regulated kinase | AKT protein | MAP kinase | Breast cancer | Immunofluorescence | 1-Phosphatidylinositol 3-kinase | Metastases | Index Medicus
Journal Article
No results were found for your search.

Cannot display more than 1000 results, please narrow the terms of your search.