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Canadian medical education journal, ISSN 1923-1202, 04/2020, Volume 11, Issue 2, pp. e31 - e153
Journal Article
European journal of medicinal chemistry, ISSN 0223-5234, 07/2018, Volume 155, pp. 1 - 12
Nifedipine and isradipine are prominent examples of calcium channel blockers with a 1,4-dihydropyridine (DHP) scaffold. Although successfully used in clinics... 
Molecular modelling | Whole cell patch clamp | Hexahydroquinoline | 1,4-dihydropyridine | Calcium channel | Binding mechanism | Hypertension | Calcium channels | Analysis | Calcium channel blockers | Pharmacy | Molecular dynamics | Physiological aspects | Drugstores | Index Medicus
Journal Article
FEBS letters, ISSN 0014-5793, 10/2011, Volume 585, Issue 20, pp. 3259 - 3262
Journal Article
Bioorganic & medicinal chemistry, ISSN 0968-0896, 06/2015, Volume 23, Issue 11, pp. 2699 - 2715
[Display omitted] Scaffold diversity is key in the ongoing exercise of discovery of novel bioactive compounds using high throughput screening (HTS). Based on... 
Synthesis | Tetrazol | Parallel | Isocyanide | Ugi | Pictet–Spengler | unclassified drug | n [[(4 chlorophenyl)[1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl]methyl] 2 3,4 dimethoxyphenyl]ethanamine | 8 ethyl 2,3 dimethoxy 8 methyl 6,8,13,13a tetrahydro 5h tetrazolo[1',5' 4,5]pyrazino [2,1 a]isoquinoline | n [2 (1h indol 3 yl)ethyl] 1 [1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl]propan 1 amine | tetracyclic tetrazole scaffold | 1 [1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl] n (3,4 dimethoxyphenethyl)cyclohexanamine | n [[1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl](4 fluorophenyl)methyl] 2 (3,4 dimethoxy phenyl)ethanamine | 8 (4 chlorophenyl) 2,3 dimethoxy 6,8,13,13a tetrahydro 5h tetrazolo[1',5' 4,5]pyrazino [2,1 a]isoquinoline | 8 isopropyl 2,3 dimethoxy 6,8,13,13a tetrahydro 5h tetrazoleo[1',5' 4,5]pyrazino [2,1 a]isoquinoline | 1 [1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl] n (3,4 dimethoxyphenethyl) 2 phenylethanamine | high throughput screening | mass spectrometry | Pictet-Spengler | multicomponent reaction chemistry | 1 [1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl] n (3,4 dimethoxyphenethyl)propan 1 amine | thin layer chromatography | 1 benzyl 4 [1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl] n (3,4 dimethoxy phenethyl)piperidin 4 amine | proton nuclear magnetic resonance | n [2 (1h indol 3 yl)ethyl] 1 benzyl 4 [1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl]piperidin 4 amine | 2,3 dimethoxy 8 phenyl 6,8,13,13a tetrahydro 5h tetrazolo[1',5' 4,5]pyrazino [2,1 a]isoquinoline | 7',12',12b',13' tetrahydro 6'h spiro[cyclohexane 1,4' tetrazolo[1'',5'' 4',5']pyrazino[1',2' 1,2]pyrido[3,4 b]indole] | 1 [1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl] n (3,4 dimethoxyphenethyl) 2 phenylpropan 1 amine | 2,3 dimethoxy 8 phenethyl 6,8,13,13a tetrahydro 5h tetrazoleo[1',5' 4,5]pyrazino [2,1 a]isoquinoline | chemical reaction | supercritical fluid chromatography | tetrazole derivative | n [2 (1h indol 3 yl)ethyl] 1 [1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl]cyclohexanamine | article | carbon nuclear magnetic resonance | n [[1,1' biphenyl] 4 yl[1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl]methyl] 2 (3,4 dimethoxyphenyl)ethanamine | controlled study | 8 (4 fluorophenyl) 2,3 dimethoxy 6,8,13,13a tetrahydro 5h tetrazolo[1',5' 4,5]pyrazino [2,1 a]isoquinoline | 8 benzyl 2,3 dimethoxy 6,8,13,13a tetrahydro 5h tetrazoleo[1',5' 4,5]pyrazino [2,1 a]isoquinoline | 8 ethyl 2,3 dimethoxy 6,8,13,13a tetrahydro 5h tetrazoleo[1',5' 4,5]pyrazino [2,1 a]isoquinoline | 1 [1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl] n (3,4 dimethoxyphenethyl) 2 methylpropan 1 amine | 8 [[1,1' biphenyl] 4 yl] 2,3 dimethoxy 6,8,13,13a tetrahydro 5h tetrazolo[1',5' 4,5]pyrazino [2,1 a]isoquinoline | 1 benzyl 2',3'dimethoxy 5',6',13',13a' tetrahydrospiro[piperidine 4,8' tetrazolo[1',5' 4,5]pyrazino [2,1 a]isoquinoline] | 4 ethyl 4,6,7,12,12b,13 hexahydro tetrazolo[1'',5'' 4',5']pyrazino[1',2' 1,2]pyrido[3,4 b]indole | 2',3'dimethoxy 5',6',13',13a' tetrahydrospiro[cyclohexane 1,8' tetrazolo[1',5' 4,5]pyrazino [2,1 a]isoquinoline] | unindexed drug | pharmacophore | n [[1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl](phenyl)methyl] 2 (3,4 dimethoxy phenyl)ethanamine | 2 [1 (2,2 dimethoxyethyl) 1h tetrazole 5 yl] n (3,4 dimethoxyphenethyl)butan 2 amine | Models, Molecular | Molecular Structure | Tetrazoles - chemical synthesis | Polycyclic Compounds - chemical synthesis | Drug Discovery | Index Medicus | Pictet-spengler
Journal Article
2010, Ashgate popular and folk music series, ISBN 9780754668626, xvi, 209
This volume offers a comprehensive range of approaches to the work of Mark E. Smith and his band The Fall in relation to music, art and politics. Mark E. Smith... 
Fall (Musical group) | Rock music | History and criticism | Smith, Mark E., 1957 Mar. 5- Criticism and interpretation | Music & Politics | European Music | Popular Music | British Studies | Smith, Mark E | Criticism and interpretation | England | 1957 Mar. 5
Book
Canadian medical education journal, ISSN 1923-1202, 04/2020, Volume 11, Issue 2, pp. e154 - e273
Journal Article
Journal Article
Bioorganic & medicinal chemistry, ISSN 0968-0896, 03/2013, Volume 21, Issue 6, pp. 1451 - 1464
Journal Article
MedChemComm, ISSN 2040-2503, 5/2015, Volume 6, Issue 5, pp. 935 - 946
A chemical genomic screen of an in-house library of small molecule heterocycles was carried out using Xenopus laevis embryos. This led to the identification of... 
Pharmacology & Pharmacy | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology
Journal Article
Neurology, ISSN 1526-632X, 10/2013, Volume 81, Issue 22, pp. 1945 - 1952
OBJECTIVES:To validate the ability of candidate CSF biomarkers to distinguish between the 2 main forms of frontotemporal lobar degeneration (FTLD), FTLD with... 
Ab42 5 b-amyloid 1-42 | FTD 5 frontotemporal degeneration | FTLD 5 frontotemporal lobar degeneration | FTLD-TDP 5 frontotemporal lobar degeneration with TAR DNA-binding protein 43 (TDP-43) inclusions | P-Tau181 5 Tau phosphorylated at threonine 181 | Penn 5 University of Pennsylvania | PN 5 peripheral neuropathy | AUC 5 area under the curve | ALS 5 amyotrophic lateral sclerosis | ROC 5 receiver operating characteristic | T-Tau 5 total Tau | FTLD-Tau 5 frontotemporal lobar degeneration with Tau inclusions | CI 5 confidence interval | AD 5 Alzheimer disease | IL 5 interleukin | PSP 5 progressive supranuclear palsy | Frontotemporal Lobar Degeneration - cerebrospinal fluid | Phosphorylation | Peptide Fragments - cerebrospinal fluid | Humans | Intercellular Signaling Peptides and Proteins - genetics | Male | tau Proteins - cerebrospinal fluid | Chi-Square Distribution | DNA-Binding Proteins - genetics | Threonine - metabolism | Proteins - genetics | DNA-Binding Proteins - cerebrospinal fluid | Interleukin-23 - cerebrospinal fluid | Frontotemporal Lobar Degeneration - diagnosis | Sensitivity and Specificity | Amyloid beta-Peptides - cerebrospinal fluid | Female | C9orf72 Protein | Biomarkers - cerebrospinal fluid | Frontotemporal Lobar Degeneration - genetics | Cohort Studies | Index Medicus | Abridged Index Medicus | 111 | 166 | 178
Journal Article
Medicinal chemistry (Shp-sariqah, United Arab Emirates), ISSN 1573-4064, 05/2018, Volume 14, Issue 3, pp. 269 - 280
Journal Article