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index medicus (43) 43
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biochemistry & molecular biology (26) 26
delta-3-oxosteroid 5-beta-reductase (20) 20
srd5b1 akr1d1 (17) 17
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endocrinology & metabolism (14) 14
3-alpha-hydroxysteroid dehydrogenase (13) 13
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5-beta-reductase akr1d1 (10) 10
aldo-keto reductases (10) 10
hepatitis (10) 10
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liver (9) 9
aldo-keto reductase (8) 8
delta-3-oxosteroid 5-beta-reductase deficiency (8) 8
delta-4-3-ketosteroid 5-beta-reductase (8) 8
mass spectrometry (8) 8
metabolism (8) 8
oxidoreductases - chemistry (8) 8
substrate specificity (8) 8
toxicology (8) 8
bile acids and salts - biosynthesis (7) 7
bile acids and salts - metabolism (7) 7
bile-acids (7) 7
cholestasis (7) 7
deoxycholic acid (7) 7
gene analysis (7) 7
keto reductase superfamily (7) 7
kinetics (7) 7
physiological aspects (7) 7
steroids - metabolism (7) 7
substrate-specificity (7) 7
3-hydroxysteroid dehydrogenases - metabolism (6) 6
5 beta-reductase (6) 6
aldehyde reductase (6) 6
analysis (6) 6
bile acids (6) 6
biosynthesis (6) 6
chenodeoxycholic acid (6) 6
diagnosis (6) 6
enzymes (6) 6
expressed enzyme (6) 6
infant (6) 6
metabolites (6) 6
models, molecular (6) 6
mutations (6) 6
pediatrics (6) 6
rat-liver (6) 6
reductase (6) 6
research (6) 6
steroid metabolism (6) 6
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alcohol oxidoreductases - metabolism (5) 5
bile (5) 5
catalysis (5) 5
genetics & heredity (5) 5
medicine, research & experimental (5) 5
oxidation-reduction (5) 5
steroid 5-beta-reductase akr1d1 (5) 5
steroid hormones (5) 5
superfamily (5) 5
ursodeoxycholic acid (5) 5
20-hydroxysteroid dehydrogenases - metabolism (4) 4
3-alpha-hydroxysteroid dihydrodiol dehydrogenase (4) 4
3-beta-hydroxy-delta-c-27-steroid oxidoreductase deficiency (4) 4
3-hydroxysteroid dehydrogenases - chemistry (4) 4
5-beta-reductase (4) 4
5β-reductase (4) 4
alcohol oxidoreductases - genetics (4) 4
bile acid (4) 4
bile acids and salts - blood (4) 4
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cerebrotendinous xanthomatosis (4) 4
children (4) 4
cholestasis - diagnosis (4) 4
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cytosolic hydroxysteroid dehydrogenases (4) 4
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failure (4) 4
genetics (4) 4
hormone-metabolism (4) 4
human liver (4) 4
infant, newborn (4) 4
liver - enzymology (4) 4
liver - metabolism (4) 4
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Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 2009, Volume 301, Issue 1, pp. 191 - 198
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2010, Volume 285, Issue 32, pp. 24529 - 24537
Bile acid deficiency is a serious syndrome in newborns that can result in death if untreated. 5 beta-Reductase deficiency is one form of bile acid deficiency... 
HUMAN DELTA-3-OXOSTEROID 5-BETA-REDUCTASE | GENE ANALYSIS | METABOLISM | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SUPERFAMILY | RECEPTOR | SRD5B1 AKR1D1 | BINDING | ALDO-KETO REDUCTASE | 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE | Steroid | Molecular Bases of Disease | Bile Acid | Mutant | Enzyme Kinetics | Protein Stability | Enzymology | 5beta-Reduction | Aldo-keto Reductase
Journal Article
STEROIDS, ISSN 0039-128X, 05/2014, Volume 83, pp. 17 - 26
Journal Article
Journal Article
STEROIDS, ISSN 0039-128X, 04/2008, Volume 73, Issue 4, pp. 417 - 423
Journal Article
Journal of Inherited Metabolic Disease, ISSN 0141-8955, 5/2013, Volume 36, Issue 3, pp. 565 - 573
Journal Article
BIOCHEMISTRY, ISSN 0006-2960, 12/2008, Volume 47, Issue 51, pp. 13537 - 13546
The 5 beta-reductases (AKR1D1-3) are unique enzymes able to catalyze efficiently and in a stereospecific manner the 50-reduction of the C4-C5 double bond found... 
RAT-LIVER | DELTA-3-OXOSTEROID 5-BETA-REDUCTASE | LIVER 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE | KETO REDUCTASE SUPERFAMILY | TISSUE DISTRIBUTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | 20-ALPHA-HYDROXYSTEROID DEHYDROGENASE | KINETIC MECHANISM | EXPRESSED ENZYME | BILE-ACIDS | HEMOGLOBIN SYNTHESIS
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 2011, Volume 191, Issue 1, pp. 217 - 226
Endometriosis is a very common disease that is characterized by increased formation of estradiol and disturbed progesterone action. This latter is usually... 
5α-Reductase (SRD5A) | 5α-Dihydroprogesterone | Progesterone receptor B (PR-B) | 20α-Hydroxyprogesterone | 5β-Reductase (AKR1D1) | 5 alpha-Reductase (SRD5A) | BIOCHEMISTRY & MOLECULAR BIOLOGY | 5 beta-Reductase (AKR1D1) | PELVIC ENDOMETRIOSIS | 5 alpha-Dihydroprogesterone | RECEPTOR | DEHYDROGENASE-ACTIVITY | STEROID 5-BETA-REDUCTASE AKR1D1 | 5-ALPHA-REDUCTASE | BREAST-CANCER CELLS | 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE-2 EXPRESSION | REVEALS ROLES | ESTROGEN | PHARMACOLOGY & PHARMACY | TOXICOLOGY | 20 alpha-Hydroxyprogesterone | B PR-B | Up-Regulation | Endometriosis - genetics | Humans | RNA, Messenger - metabolism | Hydroxyprostaglandin Dehydrogenases - metabolism | Receptors, Progesterone - metabolism | 3-Hydroxysteroid Dehydrogenases - metabolism | Adult | Female | Hydroxysteroid Dehydrogenases - metabolism | 20-Hydroxysteroid Dehydrogenases - genetics | Membrane Proteins - genetics | Down-Regulation | RNA, Messenger - genetics | Endometriosis - pathology | Hydroxysteroid Dehydrogenases - genetics | 20-Hydroxysteroid Dehydrogenases - metabolism | Hydroxyprostaglandin Dehydrogenases - genetics | Gene Expression Regulation, Enzymologic | Aldo-Keto Reductase Family 1 Member C3 | Estradiol Dehydrogenases - genetics | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - genetics | Endometriosis - metabolism | Progesterone - metabolism | 3-Hydroxysteroid Dehydrogenases - genetics | Immunohistochemistry | Messenger RNA | Isoenzymes | Analysis | Physiological aspects | Endometriosis | Oxidoreductases | Progesterone | Index Medicus
Journal Article
Journal of Pediatric Gastroenterology and Nutrition, ISSN 0277-2116, 06/2017, Volume 64, Issue 6, pp. 864 - 868
Journal Article