X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
chemistry, organic (83) 83
5-endo-trig (39) 39
nucleophilic 5-endo-trig cyclization (33) 33
cyclization (27) 27
5-endo-trig cyclization (26) 26
chemistry, multidisciplinary (19) 19
derivatives (14) 14
organic-synthesis (13) 13
fluorine (12) 12
gem-difluoroalkenes (12) 12
heterocycles (9) 9
index medicus (9) 9
radical cyclization (9) 9
ring-closure (9) 9
alpha-halo amides (8) 8
f bond activation (8) 8
formal synthesis (8) 8
stereoselective-synthesis (8) 8
carbonyl-compounds (7) 7
chemical properties (7) 7
cyclisation (7) 7
facile synthesis (7) 7
letter (7) 7
synthesis (7) 7
5-endo-trig radical cyclization (6) 6
alkenes (6) 6
analysis (6) 6
beta-lactams (6) 6
catalysis (6) 6
esters (6) 6
lactams (6) 6
one-carbon units (6) 6
radical (6) 6
radical cascade (6) 6
radicals (6) 6
vinylic fluorines (6) 6
-gamma-lycorane (5) 5
4-exo-trig (5) 5
5-endo-trig radical cyclizations (5) 5
acids (5) 5
activation (5) 5
alcohols (5) 5
alkaloid (5) 5
arylboronic acids (5) 5
asymmetric induction (5) 5
chemical synthesis (5) 5
conjugate addition (5) 5
cross-coupling reactions (5) 5
diazo-compounds (5) 5
difluoromethyl 2-pyridyl sulfone (5) 5
gem-difluoroolefins (5) 5
intramolecular cyclization (5) 5
molecular structure (5) 5
pyrrolidines (5) 5
regiochemistry (5) 5
research (5) 5
rules (5) 5
temperature (5) 5
tributyltin hydride (5) 5
-γ-lycorane (4) 4
2,4-disubstituted 3-fluoroquinolines (4) 4
5-endo-trig cyclizations (4) 4
5-membered lactams (4) 4
alkaloids (4) 4
alkylation (4) 4
alpha-trifluoromethylstyrenes (4) 4
atom (4) 4
biological-activity (4) 4
c bond formation (4) 4
crafts-type cyclization (4) 4
cyclizations (4) 4
design (4) 4
efficient synthesis (4) 4
enamides (4) 4
fluorides (4) 4
fluoroalkene (4) 4
functionalization (4) 4
grignard-reagents (4) 4
homoallylic alcohols (4) 4
kinetics (4) 4
olefins (4) 4
oxidative cyclization (4) 4
palladium (4) 4
pyroglutamates (4) 4
reagents (4) 4
route (4) 4
secondary amides (4) 4
stereocontrolled synthesis (4) 4
stereoselectivity (4) 4
substituted pyrrolidinones (4) 4
tetrahydrofurans (4) 4
-mesembranol (3) 3
acid (3) 3
alkenes - chemistry (3) 3
alkyl-halides (3) 3
alpha (3) 3
alpha-bromo amides (3) 3
aryl halides (3) 3
asymmetric-synthesis (3) 3
bearing (3) 3
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Asian Journal of Organic Chemistry, ISSN 2193-5807, 05/2019, Volume 8, Issue 5, pp. 637 - 640
3‐(Trifluoromethyl)indoles were successfully synthesized by cyclization through intramolecular oxidative C−H/N−H coupling of α‐(trifluoromethyl)styrenes... 
oxidation | indole | radical | cyclization | fluorine | BEARING METHOXYCARBONYL | NUCLEOPHILIC 5-ENDO-TRIG CYCLIZATION | ARENES | CHEMISTRY, ORGANIC | TETHERED 1,7-ENYNES | AMINATION | ETHERS | BICYCLIZATION | RADICAL CYCLIZATION | INHIBITORS | TRIFLUOROMETHYLATION
Journal Article
Asian Journal of Organic Chemistry, ISSN 2193-5807, 02/2019, Volume 8, Issue 2, pp. 279 - 282
A mild and efficient method for the synthesis of unsymmetrical 2,5‐disubstituted 1,3,4‐oxadiazoles by condensation of gem‐difluoroalkenes with acyl hydrazides... 
acyl hydrazides | gem-difluoroalkenes | cyclization | synthetic methods | 1,3,4-oxadiazoles | C-H ALKYLATION | ACCESS 1,3,4-OXADIAZOLES | ONE-POT SYNTHESIS | NUCLEOPHILIC 5-ENDO-TRIG CYCLIZATION | CHEMISTRY, ORGANIC | CARBONYL-COMPOUNDS | F BOND ACTIVATION | FUNCTIONALIZATION | CRAFTS-TYPE CYCLIZATION | RING | OXIDATIVE CYCLIZATION
Journal Article
Organic Letters, ISSN 1523-7060, 10/2007, Volume 9, Issue 22, pp. 4431 - 4434
Heck-type 4-exo-trig cyclization of linear 2-enol triflate-1,5-hexadienes provides functionalized methylene cyclobutanes. Intramolecular palladium coordination... 
CHEMISTRY, ORGANIC | 5-ENDO-TRIG | ALKENYL | INDOLES | PALLADIUM-CATALYZED CYCLIZATION | ALPHA,BETA-UNSATURATED CARBONYL
Journal Article
Organic Letters, ISSN 1523-7060, 08/2006, Volume 8, Issue 18, pp. 4059 - 4062
4-(2‘-Bromoaryloxymethylene)-9-methyl-2,3,9-trihydrothiopyrano[2,3-b]indoles under tri-n-butyltin hydride mediated aryl radical cyclization furnished... 
TRIBUTYLTIN HYDRIDE | ALPHA-BROMO AMIDES | ACIDS | ANNULATED SULFUR HETEROCYCLES | RING | REGIOCHEMISTRY | CHEMISTRY, ORGANIC | 5-ENDO-TRIG | PYRROLES | SIGMATROPIC REARRANGEMENT | BETA-LACTAMS
Journal Article
Synlett, ISSN 0936-5214, 01/2013, Volume 24, Issue 1, pp. 57 - 60
Abstract 3,3-Difluoroallylic ketones readily undergo nucleophilic 5 -endo-trig cyclization through their metal enolates to afford 5-fluor­inated... 
letter | furans | 5- endo - trig | vinylic substitution | alkenes | cyclization | ketone enolates | fluorine | SUBSTITUTION | C BOND FORMATION | CHEMISTRY, ORGANIC | BETA,BETA-DIFLUOROSTYRENES | 5-endo-trig | INTRAMOLECULAR CYCLIZATION | FACILE SYNTHESIS | DIASTEREOSELECTIVE SYNTHESIS | HETEROCYCLES | RULES | RING-CLOSURE | 2,4-DISUBSTITUTED 3-FLUOROQUINOLINES
Journal Article
Organic Letters, ISSN 1523-7060, 05/2003, Volume 5, Issue 9, pp. 1455 - 1458
o-Cyano-β,β-difluorostyrenes react with organolithiums selectively at the cyano carbon to generate the corresponding sp2 nitrogen anions, which in turn undergo... 
CHEMISTRY, ORGANIC | NUCLEOPHILIC 5-ENDO-TRIG CYCLIZATION | DERIVATIVES | Quinolines - chemical synthesis | Hydrocarbons, Fluorinated - chemical synthesis | Styrenes - chemistry | Cyclization | Isoquinolines - chemical synthesis | Nitriles - chemistry
Journal Article
Advanced Synthesis & Catalysis, ISSN 1615-4150, 12/2019, Volume 361, Issue 24, pp. 5661 - 5676
Here we report a mild and regioselective copper‐catalyzed direct synthesis of multi‐substituted and functionalized NH‐pyrroles in high yields from diverse... 
NH-Pyrrole | NH-enamine | 5-Endo-trig radical cyclization | captodative-stabilization | Cu(I)-catalyst | Organic chemistry | Agrochemicals | Aromatic compounds | Natural products | Pyrroles | Organometallic compounds | Catalysis | Chemical synthesis | Substrates | Carbonyls
Journal Article
Synthesis, ISSN 0039-7881, 4/2002, Volume 2002, Issue 6, pp. 695 - 713
Journal Article
Nature Communications, ISSN 2041-1723, 06/2015, Volume 6, Issue 1, p. 7472
Fluoroalkenes represent a class of privileged structural motifs, which found widespread use in medicinal chemistry. However, the synthetic access to... 
OLEFINIC TRIFLUOROMETHYLATION | CRAFTS-TYPE CYCLIZATION | H FLUOROALKENYLATION | VINYLIC FLUORINES | MULTIDISCIPLINARY SCIENCES | ARENES | ARYL | ALKYNES | CLEAVAGE | 5-ENDO-TRIG CYCLIZATION | FLUOROOLEFINS
Journal Article
Organic & Biomolecular Chemistry, ISSN 1477-0520, 03/2017, Volume 15, Issue 10, pp. 2253 - 2258
A simple base mediated reaction of 2-trifluoromethyl-1,3-conjugated enynes with N-acetylated 2-aminomalonates was developed, which could deliver two distinct... 
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 2017, Volume 15, Issue 10, pp. 2253 - 2258
A simple base mediated reaction of 2-trifluoromethyl-1,3-conjugated enynes with N-acetylated 2-aminomalonates was developed, which could deliver two distinct... 
ORGANIC-SYNTHESIS | FACILE ACCESS | HETEROCYCLES | NUCLEOPHILIC 5-ENDO-TRIG CYCLIZATION | BUILDING-BLOCKS | GOLD-CATALYZED CYCLIZATION | INTRAMOLECULAR HYDROAMINATION | CHEMISTRY, ORGANIC | RECENT PROGRESS | OXIDATIVE CYCLIZATION | H BOND FUNCTIONALIZATION
Journal Article
Heterocycles, ISSN 0385-5414, 2013, Volume 87, Issue 3, pp. 527 - 545
This review focuses on radical cyclizations for the synthesis of a variety of alkaloids. Emphasis has been placed on radical cascades that afford synthesis of... 
5-endo-Trig | 5-EXO | (+/-)-ISOSTEMONAMIDE | CHEMISTRY, ORGANIC | FORMAL TOTAL-SYNTHESIS | CASCADE | 6-EXO | Radical | SKELETON | Alkaloid | ALPHA-BROMO AMIDES | STEREOSELECTIVE-SYNTHESIS | Radical Cascade | 5-MEMBERED LACTAMS | ENAMIDES
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2017, Volume 58, Issue 5, pp. 375 - 392
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 11/2012, Volume 51, Issue 48, pp. 12059 - 12062
Replacing the fluorine: 3‐Fluorinated pyrazoles were regioselectively synthesized by sequential substitution reactions of 2‐trifluoromethyl‐1‐alkenes (see... 
pyrazole | fluoroalkene | nucleophilic substitution | cyclization | fluorine | PYRAZOLES | NUCLEOPHILIC 5-ENDO-TRIG CYCLIZATION | VINYLIC FLUORINES | ALPHA | CHEMISTRY, MULTIDISCIPLINARY | HETEROCYCLES | DIFLUOROALKENES | 1,1-DIFLUORO-1-ALKENES | BEARING | ONE-CARBON UNITS | CONCISE SYNTHESIS | Universities and colleges | Fluorides | Substitution reactions | Synthesis | Fluorine | Pyrazole
Journal Article
Synlett, ISSN 0936-5214, 07/2009, Volume 2009, Issue 12, pp. 1997 - 2001
Abstract Synthesis of new thiazolidine-fused five-, six-, and seven-membered heterocycles through vinylogous N-acyliminium ion-cyclization sequence, involving... 
letter | Lactams | Iminium ions | Cyclization | Fused-ring systems | Neighboring-group effects | neighboring-group effects | lactams | fused-ring systems | ESTERS | CHEMISTRY, ORGANIC | cyclization | DERIVATIVES | iminium ions | PARTICIPATION | 5-ENDO-TRIG CYCLIZATION
Journal Article
Yakugaku Zasshi, ISSN 0031-6903, 2012, Volume 132, Issue 12, pp. 1413 - 1430
Journal Article
by He, YW and Anand, D and Sun, ZC and Zhou, L
ORGANIC LETTERS, ISSN 1523-7060, 05/2019, Volume 21, Issue 10, pp. 3769 - 3773
A visible-light-promoted redox neutral gamma,gamma-difluoroallylation of cycloketone oxime ethers with trifluor-omethyl alkenes through C-C and C-F bond... 
FUNCTIONALIZATION | H CYANOALKYLATION | SUBSTITUTION | ACTIVATION | NUCLEOPHILIC 5-ENDO-TRIG CYCLIZATION | ACIDS | ESTERS | CHEMISTRY, ORGANIC | GEM-DIFLUOROALKENES | CARBONYL-COMPOUNDS | IMINYL RADICALS
Journal Article
No results were found for your search.

Cannot display more than 1000 results, please narrow the terms of your search.