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Chemical communications (Cambridge, England), ISSN 1359-7345, 11/2018, Volume 54, Issue 93, pp. 13107 - 13110
5-Formyluracil (5fU) based probes were designed and synthesized to detect Al3+ ions in vitro and in biological systems. These probes were synthesised using... 
5-FORMYLPYRIMIDINE | CHEMISTRY, MULTIDISCIPLINARY | DNA | 5-FORMYLCYTOSINE | Index Medicus
Journal Article
by Xiong, J and Ye, TT and Ma, CJ and Cheng, QY and Yuan, BF and Feng, YQ
NUCLEIC ACIDS RESEARCH, ISSN 0305-1048, 02/2019, Volume 47, Issue 3, pp. 1268 - 1277
In addition to DNA cytosine methylation (5-methyl-2-deoxycytidine, m(5)dC), DNA adenine methylation (N-6-methyl-2-deoxyadenosine, m(6)dA) is another DNA... 
EPIGENETIC MARK | METHYLATION | 5-METHYLCYTOSINE | RNA | N-6-ADENINE | SUBSTRATE | BIOCHEMISTRY & MOLECULAR BIOLOGY | 5-HYDROXYMETHYLCYTOSINE | ADDUCTS | 5-FORMYLCYTOSINE | BASE
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 06/2016, Volume 7, pp. 12039 - 12039
Epitranscriptome modifications are required for structure and function of RNA and defects in these pathways have been associated with human disease. Here we... 
METHYLTRANSFERASE MISU NSUN2 | NONCODING RNA | HYPERTROPHIC CARDIOMYOPATHY | 5-METHYLCYTOSINE | DNA | MULTIDISCIPLINARY SCIENCES | BOVINE LIVER | MITOCHONDRIAL TRANSFER-RNAS | ANTICODON | 5-FORMYLCYTOSINE | GENOME | Index Medicus
Journal Article
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, ISSN 0002-7863, 04/2019, Volume 141, Issue 16, pp. 6420 - 6429
While some DNA base modifications such as 5-methylcytosine have been known and studied for decades, recent discoveries of a number of other modified bases have... 
RESOLUTION ANALYSIS | METHYLATION | N-6-ADENINE | 5-METHYL-CYTOSINE | TRANSCRIPTION | CYTOSINE MODIFICATIONS | 5-HYDROXYMETHYLCYTOSINE | WIDE | CHEMISTRY, MULTIDISCIPLINARY | 5-FORMYLCYTOSINE | GENOME
Journal Article
EMBO JOURNAL, ISSN 0261-4189, 10/2016, Volume 35, Issue 19, pp. 2104 - 2119
Mitochondrial gene expression uses a non-universal genetic code in mammals. Besides reading the conventional AUG codon, mitochondrial (mt-)tRNA(Met) mediates... 
RNA modification | METHYLATION | METHYLTRANSFERASE | PROTEIN | mitochondria | BIOCHEMISTRY & MOLECULAR BIOLOGY | NSUN3 | RIBOSOMAL-RNA | CELL BIOLOGY | BOX C/D | ABH1 | BIOGENESIS | DNA | translation | 5-HYDROXYMETHYLCYTOSINE | TRANSFER-RNA | 5-FORMYLCYTOSINE
Journal Article
Chemical Communications, ISSN 1359-7345, 2018, Volume 54, Issue 12, pp. 1497 - 1500
An azide and hydrazine tethered to a naphthalimide analogue was created to selectively react with 5-formyluracil in one system and fluorogenically label... 
CPG DINUCLEOTIDE | 5-METHYLCYTOSINE | RNA | CYTOSINE MODIFICATIONS | ENDOGENOUS FORMALDEHYDE | THYMINE | OXIDATION-PRODUCTS | CHEMISTRY, MULTIDISCIPLINARY | STEM-CELL DNA | FLUORESCENT-PROBE | 5-FORMYLCYTOSINE
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 10/2018, Volume 140, Issue 41, pp. 13190 - 13194
High-resolution detection of genome-wide 5-hydroxymethylcytosine (5hmC) sites of small-scale samples remains challenging. Here, we present hmC-CATCH, a... 
METHYLATION | MAMMALIAN DNA | 5-METHYLCYTOSINE | SIGNATURES | CONVERSION | PEROXOTUNGSTATE | CHEMISTRY, MULTIDISCIPLINARY | 5-FORMYLCYTOSINE | GENOME | 5-CARBOXYLCYTOSINE | CELL-FREE DNA | Index Medicus
Journal Article
CHEMICAL SCIENCE, ISSN 2041-6520, 04/2019, Volume 10, Issue 14, pp. 3937 - 3942
We report proof of principle biomimetic switching of transcription in vitro through non-natural chemical reactions in the major groove of DNA templates.... 
METHYLATION | 5-CARBOXYCYTOSINE | BIOSYNTHESIS | 5-(HYDROXYMETHYL) URACIL | 5-HYDROXYMETHYLCYTOSINE | PROTECTING GROUPS | CLEAVAGE | CHEMISTRY, MULTIDISCIPLINARY | 5-FORMYLCYTOSINE | CYTOSINE | BASE
Journal Article
Chemical Science, ISSN 2041-6520, 2019, Volume 10, Issue 2, pp. 447 - 452
5-Hydroxymethylcytosine (5hmC) is known as one of the vital players in nuclear reprogramming and the process of active DNA demethylation. Although the... 
5-METHYLCYTOSINE | CONVERSION | MOUSE | GENES | MECHANISMS | TET PROTEINS | CHEMISTRY, MULTIDISCIPLINARY | 5-FORMYLCYTOSINE | REVEALS
Journal Article
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, ISSN 1433-7851, 09/2017, Volume 56, Issue 37, pp. 11268 - 11271
Until recently, it was believed that the genomes of higher organisms contain, in addition to the four canonical DNA bases, only 5-methyl-dC (m(5)dC) as a... 
DNA METHYLATION | MAMMALIAN DNA | 5-METHYLCYTOSINE | methyldeoxyadenosine | N-6-METHYLADENINE | methyldeoxycytidine | CHEMISTRY, MULTIDISCIPLINARY | epigenetics | BASE | N-6-ADENINE | DNA | mass spectrometry | 5-HYDROXYMETHYLCYTOSINE | N-4-METHYLCYTOSINE | 5-FORMYLCYTOSINE | 5-CARBOXYLCYTOSINE
Journal Article
by Wang, XL and Yu, Y and Zhou, ZN and Liu, YY and Yang, YJ and Xu, JH and Chen, JQ
JOURNAL OF PHYSICAL CHEMISTRY B, ISSN 1520-6106, 07/2019, Volume 123, Issue 27, pp. 5782 - 5790
DNA methylation and demethylation are the key steps in epigenetics. Emerging studies have demonstrated that these two processes play crucial roles in mammalian... 
EXCITED-STATE LIFETIMES | CYCLOBUTANE PYRIMIDINE DIMERS | TRIPLET-STATE | DYNAMICS | CHEMISTRY, PHYSICAL | 5-HYDROXYMETHYLCYTOSINE | PHOTOCHEMISTRY | INTERNAL-CONVERSION | CYTOSINE METHYLATION | 5-FORMYLCYTOSINE | 5-CARBOXYLCYTOSINE
Journal Article
Chemical Science, ISSN 2041-6520, 2018, Volume 9, Issue 36, pp. 7247 - 7252
Transcription-activator-like effectors (TALEs) are repeat-based proteins featuring programmable DNA binding. The repulsion of TALE repeats by 5-methylcytosine... 
EFFECTORS | SPECIFICITY | CONVERSION | CYTOSINE MODIFICATIONS | 5-HYDROXYMETHYLCYTOSINE | PROTEINS | CHEMISTRY, MULTIDISCIPLINARY | 5-FORMYLCYTOSINE | 5-CARBOXYLCYTOSINE | DISCOVERY | BASE
Journal Article
Organic Letters, ISSN 1523-7060, 09/2016, Volume 18, Issue 17, pp. 4368 - 4371
Investigation of the function of the new epigenetic bases requires the development of stabilized analogues that are stable during base excision repair (BER).... 
THYMINE DNA GLYCOSYLASE | MAMMALIAN DNA | 5-METHYLCYTOSINE | NUCLEOSIDES | DEMETHYLATION | CHEMISTRY, ORGANIC | 5-HYDROXYMETHYLCYTOSINE | EXCISION | DECARBOXYLATION | 5-CARBOXYLCYTOSINE | 5-FORMYLCYTOSINE
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 11/2018, Volume 140, Issue 46, pp. 15842 - 15849
In mammals, 5-formylcytosine (5fC) has been identified as an important mark, which plays significant roles in active DNA demethylation and also in epigenetic... 
RESTRICTION ENZYME | TRANSCRIPTION | POLYMERASE | 5-HYDROXYMETHYLCYTOSINE | STEADY-STATE | THYMINE DNA | STATE KINETIC-ANALYSIS | CHEMISTRY, MULTIDISCIPLINARY | 5-FORMYLCYTOSINE | 5-CARBOXYLCYTOSINE | BASE | Index Medicus
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 03/2019, Volume 47, Issue 5, pp. e28 - e28
Abstract Since the discovery of 5-hydroxymethylcytosine (5hmC) as a prominent DNA modification found in mammalian genomes, an emergent question has been what... 
TET ENZYMES | 5-METHYLCYTOSINE | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE-EXPRESSION | PATTERNS | 5-FORMYLCYTOSINE | DIFFERENTIAL DNA METHYLATION | Methods Online
Journal Article