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Psychopharmacology, ISSN 0033-3158, 07/2017, Volume 234, Issue 13, pp. 2031 - 2046
Journal Article
Journal Article
Molecular Neurobiology, ISSN 0893-7648, 4/2016, Volume 53, Issue 3, pp. 2003 - 2015
5-Hydroxytryptamine 1A receptor and galanin receptor 1 belong to the G protein-coupled receptors superfamily, and they have been described to heterodimerize... 
G protein-coupled receptor | Neurosciences | Galanin receptor | G protein signaling | Neurobiology | Protein stability | Depression | Heterodimerization | Zinc | Cell Biology | Neurology | Biomedicine | Serotonin receptor | Purified receptor | MOLECULAR-BIOLOGY | 5-HT1A RECEPTORS | CRYSTAL-STRUCTURE | DIMERIZATION | NEUROSCIENCES | DEFICIENCY | CESSATION | SPECTROSCOPY | RHODOPSIN | SURFACE-PLASMON RESONANCE | GALANIN-RECEPTOR | Surface Plasmon Resonance | Receptors, G-Protein-Coupled - metabolism | Zinc - metabolism | Electrophoresis, Polyacrylamide Gel | Humans | Protein Multimerization | Models, Molecular | Depression - metabolism | Animals | Receptor, Serotonin, 5-HT1A - chemistry | Cattle | HEK293 Cells | Fluorescence Resonance Energy Transfer | Receptors, Galanin - metabolism | Binding Sites | Receptor, Serotonin, 5-HT1A - metabolism | Receptors, G-Protein-Coupled - chemistry | GTP-Binding Proteins - metabolism | Receptors, Galanin - chemistry | Analysis | Depression, Mental | Zinc in the body | Physiological aspects | Neuropeptides | G proteins | Membrane proteins | Signal transduction | Mental depression | Index Medicus | Enginyeria química | G-protein-coupled receptor | Receptors | Cell receptors | Biotecnologia | Proteïnes G | G-protein signaling | Àrees temàtiques de la UPC | Receptors cel·lulars | Depressió psíquica
Journal Article
JOURNAL OF NEUROSCIENCE, ISSN 0270-6474, 12/2001, Volume 21, Issue 24, pp. 9917 - 9929
Anatomical evidence indicates that medial prefrontal cortex (mPFC) neurons project to the dorsal raphe nucleus (DR). In this study, we functionally... 
EFFERENT PROJECTIONS | medial prefrontal cortex | 5-hydroxytryptamine | FRONTAL-CORTEX | AUTORECEPTOR ACTIVATION | LOCAL INFUSION | NMDA receptors | NEUROSCIENCES | dorsal raphe nucleus | AMPA/KA receptors | DOPAMINE NEURONS | 5-HT1A RECEPTOR | 5-HT release | GABA receptors | IN-VIVO | RAT MIDBRAIN RAPHE | CENTRAL-NERVOUS-SYSTEM | 5-HT1A receptors | EXTRACELLULAR 5-HYDROXYTRYPTAMINE | Receptors, Glutamate - metabolism | Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors | Electric Stimulation | Rats, Wistar | Autoreceptors - metabolism | Receptors, N-Methyl-D-Aspartate - metabolism | Receptors, Serotonin - drug effects | Evoked Potentials - physiology | Male | Raphe Nuclei - cytology | Neural Pathways - physiology | Raphe Nuclei - metabolism | Serotonin Receptor Agonists - pharmacology | Neural Inhibition - physiology | Neurons - classification | Prefrontal Cortex - drug effects | Neurons - metabolism | Neurons - drug effects | Catheterization | GABA-A Receptor Antagonists | Rats | Excitatory Amino Acid Antagonists - pharmacology | 8-Hydroxy-2-(di-n-propylamino)tetralin - pharmacology | Reaction Time - physiology | Serotonin Antagonists - pharmacology | Receptors, Serotonin - metabolism | GABA Antagonists - pharmacology | Animals | Microdialysis | Raphe Nuclei - drug effects | Receptors, Neurotransmitter - agonists | Receptors, Serotonin, 5-HT1 | Serotonin - metabolism | Receptors, GABA-A - metabolism | Receptors, Neurotransmitter - metabolism | Neural Inhibition - drug effects | Prefrontal Cortex - physiology | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2004, Volume 101, Issue 31, pp. 11304 - 11309
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 05/2011, Volume 54, Issue 9, pp. 3206 - 3221
The synthesis and structure-activity relationship of a novel series of compounds with combined effects on 5-HT3A and 5-HT1A receptors and on the serotonin... 
FREELY MOVING RATS | ARYL BROMIDES | SEROTONIN REUPTAKE INHIBITORS | IN-VIVO MICRODIALYSIS | CHEMISTRY, MEDICINAL | PALLADIUM-CATALYZED SYNTHESIS | 5-HT1A RECEPTORS | MOOD DISORDERS | DRUG DISCOVERY | FRONTAL-CORTEX | ANTIDEPRESSANT-LIKE BEHAVIOR | Xenopus | Humans | Microsomes, Liver - metabolism | Receptor, Serotonin, 5-HT2C - metabolism | Sulfides - chemistry | Serotonin 5-HT1 Receptor Agonists - pharmacology | Sulfides - chemical synthesis | Piperazines - chemistry | Structure-Activity Relationship | Hippocampus - drug effects | Serotonin Uptake Inhibitors - chemical synthesis | Receptors, Serotonin, 5-HT1 - metabolism | Serotonin 5-HT1 Receptor Agonists - chemistry | Antidepressive Agents - chemistry | Oocytes - drug effects | Antidepressive Agents - pharmacology | Radioligand Assay | Serotonin 5-HT3 Receptor Antagonists - chemistry | Receptor, Serotonin, 5-HT1A - metabolism | Depressive Disorder, Major - drug therapy | Sulfides - pharmacology | Cell Line | Recombinant Proteins - antagonists & inhibitors | Drug Partial Agonism | Drug Stability | Rats | Serotonin Uptake Inhibitors - chemistry | Serotonin 5-HT1 Receptor Agonists - chemical synthesis | Recombinant Proteins - agonists | Piperazines - pharmacology | Receptors, Serotonin - metabolism | Serotonin 5-HT3 Receptor Antagonists - chemical synthesis | Serotonin Plasma Membrane Transport Proteins - metabolism | Hippocampus - metabolism | Animals | Oocytes - physiology | Receptors, Serotonin, 5-HT3 - metabolism | Serotonin - metabolism | Antidepressive Agents - chemical synthesis | Piperazines - chemical synthesis | Serotonin 5-HT3 Receptor Antagonists - pharmacology | In Vitro Techniques | Serotonin Uptake Inhibitors - pharmacology | Index Medicus
Journal Article
Brain Structure and Function, ISSN 1863-2653, 9/2011, Volume 216, Issue 3, pp. 239 - 254
The avian nidopallium caudolaterale is a multimodal area in the caudal telencephalon that is apparently not homologous to the mammalian prefrontal cortex but... 
Human | BA10 | Neurosciences | Dopamine | Rat | Fr2 | Receptor autoradiography | Prefrontal cortex | Cg1 | Glutamate | Cell Biology | Neurology | Biomedicine | Nidopallium caudolaterale | GABA | TYROSINE-HYDROXYLASE | ANATOMY & MORPHOLOGY | DOPAMINE D1 RECEPTORS | COLUMBA-LIVIA | NEUROSCIENCES | CEREBRAL-CORTEX | MUSCARINIC CHOLINERGIC RECEPTORS | DORSOLATERALIS POSTERIOR THALAMI | DOMESTIC CHICK | NEURAL MECHANISMS | BINDING-SITES | WORKING-MEMORY | Receptors, Nicotinic - metabolism | Telencephalon - metabolism | Receptor, Muscarinic M2 - metabolism | Species Specificity | Receptors, Adrenergic - metabolism | Humans | Receptors, N-Methyl-D-Aspartate - metabolism | Rats | Telencephalon - anatomy & histology | Columbidae - anatomy & histology | Receptors, Dopamine D1 - metabolism | Autoradiography | Receptors, Kainic Acid - metabolism | Animals | Image Processing, Computer-Assisted | Columbidae - metabolism | Receptors, GABA-A - metabolism | Receptors, Neurotransmitter - metabolism | Densitometry | Receptor, Muscarinic M1 - metabolism | Receptor, Serotonin, 5-HT1A - metabolism | Receptors, AMPA - metabolism | Methyl aspartate | Evolutionary biology | Analysis | Evolution | Universities and colleges | Neurochemistry | Brain research | Binding sites | Adaptations | Cortex (prefrontal) | Kainic acid receptors | Executive function | Acetylcholine receptors (muscarinic) | Glutamic acid receptors (ionotropic) | Telencephalon | N-Methyl-D-aspartic acid receptors | Glutamic acid receptors | alpha -Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid | Serotonin S1 receptors | Dopamine D1 receptors | Functional anatomy | gamma -Aminobutyric acid A receptors | Receptor density | Norepinephrine | Structure-function relationships | Index Medicus
Journal Article
Psychopharmacology, ISSN 0033-3158, 6/2014, Volume 231, Issue 11, pp. 2291 - 2298
α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor stimulation has been proposed to be a common neural mechanism of metabotropic glutamate... 
Neurosciences | AMPA receptor | Biomedicine | Ketamine | Serotonin | Metabotropic glutamate 2/3 receptor antagonist | Depression | Pharmacology/Toxicology | Psychiatry | 5-HT1A receptor | Novelty-suppressed feeding test | 5-HT1Areceptor | ANTIDEPRESSANT | Novelty-suppressedfeedingtest | RESISTANT MAJOR DEPRESSION | 5-HT1A RECEPTORS | PSYCHIATRY | INVOLVEMENT | RELEASE | NEUROSCIENCES | PREFRONTAL CORTEX | MGS0039 | ANIMAL-MODELS | PHARMACOLOGY & PHARMACY | MICE | Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors | Serotonin 5-HT1 Receptor Antagonists - pharmacology | Receptors, N-Methyl-D-Aspartate - metabolism | Male | Receptors, Metabotropic Glutamate - metabolism | Amino Acids - pharmacology | Quinoxalines - pharmacology | Piperidines - pharmacology | Dioxoles - pharmacology | Antidepressive Agents - pharmacology | Ritanserin - pharmacology | Fenclonine - pharmacology | Receptors, AMPA - metabolism | Tryptophan Hydroxylase - metabolism | Xanthenes - pharmacology | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Serotonin 5-HT2 Receptor Antagonists - pharmacology | Piperazines - pharmacology | Feeding Behavior - physiology | Feeding Behavior - drug effects | Neuropsychological Tests | Animals | Pyridines - pharmacology | Ketamine - pharmacology | Tryptophan Hydroxylase - antagonists & inhibitors | Receptors, Metabotropic Glutamate - antagonists & inhibitors | Receptors, AMPA - antagonists & inhibitors | Neurons | Amino acids | Index Medicus
Journal Article
European Journal of Clinical Pharmacology, ISSN 0031-6970, 11/2012, Volume 68, Issue 11, pp. 1465 - 1472
Buspirone, a partial 5HT1A agonist and D2 and D3 antagonist, has shown promising antiemetic efficacy when given parenterally in animal models, but its efficacy... 
Biomedicine | Buspirone | Pharmacology/Toxicology | Randomised clinical trial | Antiemetic | Postoperative nausea and vomiting | CATS | MANAGEMENT | 5-HT1A RECEPTORS | ONDANSETRON | AGONISTS | FLESINOXAN | PROPHYLAXIS | ANXIOLYTICS | PHARMACOLOGY & PHARMACY | 5-HT(1A) RECEPTOR | CISPLATIN-INDUCED EMESIS | Anti-Anxiety Agents - administration & dosage | Injections, Intravenous | Buspirone - blood | Dopamine Antagonists - pharmacokinetics | Humans | Middle Aged | Receptors, Dopamine D3 - metabolism | Antiemetics - administration & dosage | Male | Buspirone - pharmacokinetics | Receptors, Dopamine D2 - metabolism | Dopamine Antagonists - administration & dosage | Incidence | Dose-Response Relationship, Drug | Young Adult | Anti-Anxiety Agents - pharmacokinetics | Buspirone - administration & dosage | Antiemetics - pharmacokinetics | Antiemetics - therapeutic use | Aged, 80 and over | Adult | Anti-Anxiety Agents - adverse effects | Antiemetics - adverse effects | Female | Anti-Anxiety Agents - therapeutic use | Buspirone - adverse effects | Receptors, Dopamine D3 - antagonists & inhibitors | Buspirone - therapeutic use | Receptor, Serotonin, 5-HT1A - metabolism | Postoperative Nausea and Vomiting - epidemiology | Double-Blind Method | Dopamine Antagonists - therapeutic use | Serotonin 5-HT1 Receptor Agonists - therapeutic use | Serotonin 5-HT1 Receptor Agonists - adverse effects | Postoperative Nausea and Vomiting - prevention & control | Receptor, Serotonin, 5-HT1A - chemistry | Buspirone - analogs & derivatives | Dopamine Antagonists - adverse effects | Serotonin 5-HT1 Receptor Agonists - administration & dosage | Aged | Dopamine D2 Receptor Antagonists | Postoperative Nausea and Vomiting - blood | Prevention | Complications and side effects | Buspirone hydrochloride | Adults | Nausea | Analysis | Postoperative period | Vomiting | Clinical trials | Pharmacology | Drug therapy | Clinical outcomes | Index Medicus
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 12/2011, Volume 671, Issue 1-3, pp. 79 - 86
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 12/2007, Volume 103, Issue 5, pp. 2111 - 2120
Interaction between brain endocannabinoid (EC) and serotonin (5‐HT) systems was investigated by examining 5‐HT‐dependent behavioral and biochemical responses... 
tail suspension test | receptors | hypothermia | 5‐HT | antidepressants | S]GTPγS labelling | 2A/2C | ANANDAMIDE HYDROLYSIS | ANTIDEPRESSANT-LIKE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOCANNABINOID SYSTEM | MAJOR DEPRESSION | SUICIDE VICTIMS | NEUROSCIENCES | PREFRONTAL CORTEX | 5-HT2A/2C receptors | ANTAGONIST SR 141716A | CANNABINOID RECEPTOR | SEROTONIN(1A) RECEPTOR | HYPOTHERMIC RESPONSE | CB1 receptors | [S-35] GTP gamma S labelling | 5-HT1A receptors | Guanosine 5'-O-(3-Thiotriphosphate) - pharmacology | Receptor, Serotonin, 5-HT2A - genetics | Body Temperature - drug effects | Gene Expression Regulation - genetics | Amphetamines - pharmacology | Receptor, Serotonin, 5-HT2C - metabolism | Receptor, Serotonin, 5-HT1A - genetics | Autoradiography - methods | 8-Hydroxy-2-(di-n-propylamino)tetralin - pharmacology | Mice, Knockout | Serotonin Receptor Agonists - pharmacology | Animals | Body Temperature - genetics | Protein Binding - drug effects | Behavior, Animal - drug effects | Female | Mice | Receptor, Cannabinoid, CB1 - deficiency | Receptor, Serotonin, 5-HT2C - genetics | Receptor, Serotonin, 5-HT2A - metabolism | Receptor, Serotonin, 5-HT1A - metabolism | Proteins | Brain | Genotype & phenotype | Neurosciences | Chemistry | Animal behavior | Rodents | Biochemistry | Index Medicus | Efectes fisiològics | Receptors | 5-HT2A receptors | Serotonina | Antidepressants | Cannabinoides
Journal Article