X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
biochemistry & molecular biology (277) 277
animals (274) 274
glycolysis (251) 251
6-phosphofructo-2-kinase (239) 239
index medicus (178) 178
humans (176) 176
fructose 2,6-bisphosphate (162) 162
rats (144) 144
expression (138) 138
phosphofructokinase-2 (136) 136
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (133) 133
phosphorylation (128) 128
phosphofructokinase-2 - metabolism (110) 110
metabolism (106) 106
molecular sequence data (101) 101
male (100) 100
fructose (97) 97
6-phosphofructo-2-kinase fructose-2,6-bisphosphatase (94) 94
fructose-2,6-bisphosphatase (90) 90
amino acid sequence (81) 81
mice (80) 80
biophysics (79) 79
cell biology (75) 75
kinetics (75) 75
phosphofructokinase-2 - genetics (75) 75
glucose (74) 74
liver - enzymology (72) 72
enzymes (70) 70
activation (67) 67
liver (65) 65
base sequence (63) 63
fructosediphosphates - metabolism (59) 59
gene expression (58) 58
phosphotransferases - metabolism (55) 55
phosphoric monoester hydrolases - metabolism (53) 53
cancer (52) 52
female (52) 52
glucose - metabolism (50) 50
glucose metabolism (50) 50
hypoxia (50) 50
insulin (50) 50
phosphoric monoester hydrolases - genetics (50) 50
phosphotransferases - genetics (50) 50
kinases (49) 49
pfkfb3 (48) 48
oncology (46) 46
proteins (45) 45
apoptosis (44) 44
bifunctional enzyme (43) 43
fructose-2,6-bisphosphate (43) 43
site-directed mutagenesis (43) 43
glucose-metabolism (42) 42
binding sites (41) 41
inhibition (41) 41
amino-acid-sequence (39) 39
cell line, tumor (39) 39
physiological aspects (39) 39
gene (38) 38
phosphofructokinase (38) 38
mutagenesis, site-directed (37) 37
crystal-structure (36) 36
escherichia-coli (36) 36
messenger-rna (36) 36
molecular-cloning (36) 36
rat-liver (36) 36
research (36) 36
endocrinology & metabolism (35) 35
growth (35) 35
analysis (34) 34
cell proliferation (34) 34
cloning, molecular (34) 34
signal transduction (33) 33
inducible 6-phosphofructo-2-kinase (32) 32
proliferation (32) 32
recombinant proteins - metabolism (32) 32
cell line (31) 31
isoenzymes - metabolism (31) 31
rna, messenger - metabolism (31) 31
sequence (31) 31
multienzyme complexes - metabolism (30) 30
rat-liver 6-phosphofructo-2-kinase (30) 30
enzyme (29) 29
phosphoric monoester hydrolases - chemistry (29) 29
gene-expression (28) 28
liver 6-phosphofructo-2-kinase fructose-2,6-bisphosphatase (28) 28
6-phosphofructo-2-kinase pfkfb3 (27) 27
dependent protein-kinase (27) 27
multienzyme complexes - genetics (27) 27
phosphofructokinase-2 - antagonists & inhibitors (27) 27
article (26) 26
genes (26) 26
glycolysis - drug effects (26) 26
heart 6-phosphofructo-2-kinase (26) 26
isoenzymes - genetics (26) 26
mechanism (26) 26
myocardium - enzymology (26) 26
phosphotransferases - chemistry (26) 26
cells, cultured (25) 25
enzyme activation (25) 25
gluconeogenesis (25) 25
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


世界胃肠病学杂志:英文版(电子版), ISSN 1007-9327, 2014, Volume 20, Issue 38, pp. 13705 - 13717
Enzymes 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 and-4(PFKFB-3 and PFKFB-4)play a significant role in the regulation of glycolysis in cancer... 
6-phosphofructo-2-kinase/fructose-2,6-bisphosphata | MKN45 | NUGC3 | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-4 | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 | Hypoxia inducible factor | Lung cancer | Hypoxia | PST-1 | Gastric cancer | Panc1 | ACTIVATED PROTEIN-KINASE | MESSENGER-RNA EXPRESSION | 6-PHOSPHOFRUCTO-2-KINASE PFKFB3 | FACTOR-I | RESPONSIVE ELEMENT | HYPOXIA-INDUCIBLE FACTOR-1-ALPHA | GLUCOSE-METABOLISM | 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE GENE | GENE-EXPRESSION | MOLECULAR-CLONING | GASTROENTEROLOGY & HEPATOLOGY | Cell Proliferation | Humans | Phosphofructokinase-2 - adverse effects | Gene Expression Regulation, Neoplastic | Tumor Microenvironment | Stomach Neoplasms - pathology | Antineoplastic Agents - therapeutic use | Molecular Targeted Therapy | RNA, Messenger - metabolism | Pancreatic Neoplasms - drug therapy | Drug Design | Biomarkers, Tumor - metabolism | Stomach Neoplasms - enzymology | Stomach Neoplasms - genetics | Signal Transduction | Cell Survival | Pancreatic Neoplasms - pathology | Pancreatic Neoplasms - enzymology | Phosphofructokinase-2 - antagonists & inhibitors | Pancreatic Neoplasms - genetics | Stomach Neoplasms - drug therapy | Enzyme Inhibitors - therapeutic use | Gene Expression Regulation, Enzymologic | Animals | Phosphofructokinase-2 - metabolism | Phosphofructokinase-2 - genetics | Biomarkers, Tumor - genetics | 6-phosphofructo-2-kinase | fructose-2,6-bisphosphatase-3 | fructose-2,6-bisphosphatase-4 | Topic Highlight
Journal Article
Biochemical Journal, ISSN 0264-6021, 06/2013, Volume 452, Issue 3, pp. 531 - 543
Journal Article
Journal Article
Biochemical Journal, ISSN 0264-6021, 08/2004, Volume 381, Issue 3, pp. 561 - 579
Fru-2,6-P-2 (fructose 2,6-bisphosphate) is a signal molecule that controls glycolysis. Since its discovery more than 20 years ago, inroads have been made... 
Glycolysis | Evolution | Phosphorylation | Fructose 2,6-bisphosphate | Catalysis | Gene | PROTEIN-KINASE-C | gene | BIOCHEMISTRY & MOLECULAR BIOLOGY | glycolysis | TISSUE-SPECIFIC EXPRESSION | catalysis | FRUCTOSE 6-PHOSPHATE,2-KINASE-FRUCTOSE 2,6-BISPHOSPHATASE | RAT-LIVER 6-PHOSPHOFRUCTO-2-KINASE | evolution | SITE-DIRECTED MUTAGENESIS | HEPATOCYTE NUCLEAR FACTOR-6 | F-TYPE 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE | GENE-ENCODING 6-PHOSPHOFRUCTO-2-KINASE | AMINO-ACID-SEQUENCE | fructose 2,6-bisphosphate | phosphorylation | TRANSCRIPTION FACTOR | Phosphofructokinase-2 - physiology | Amino Acid Sequence | Glycolysis - physiology | Phosphofructokinase-2 - chemistry | Animals | Models, Biological | Humans | Models, Molecular | Molecular Sequence Data | ACC, acetyl-CoA carboxylase | NF-1, nuclear factor 1 | PI3K, phosphoinositide 3-kinase | EGF, epidermal growth factor | CAMK, Ca2 | PFK-1, 6-phosphofructo-1-kinase | AMPK, AMP-activated protein kinase | HNF, hepatocyte nuclear factor | Review | PEPCK, phosphoenolpyruvate carboxykinase | FBPase-2, fructose-2,6-bisphosphatase | PKB, protein kinase B | GRU, glucocorticoid-response unit | calmodulin-activated protein kinase | GLUT4, glucose transporter 4 | PDK, phosphoinositide-dependent protein kinase | PFK-2, 6-phosphofructo-2-kinase | enhancer-binding protein | OC, Onecut | PKC, protein kinase C | p70S6k, p70 ribosomal protein S6 kinase | EBP, CCAAT | PKA, cAMP-dependent protein kinase | Fru-2,6-P2, fructose 2,6-bisphosphate | Fru-6-P, fructose 6-phosphate | WISK, wortmannin-sensitive, insulin-stimulated protein kinase | 3D, three-dimensional | FBPase-1, fructose-1,6-bisphosphatase | iPFK-2, inducible PFK-2 | GAP, GTPase-activating protein | GR, glucocorticoid receptor | MAPK, mitogen-activated protein kinase | AK, adenylate kinase
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 08/2013, Volume 12, Issue 8, pp. 1461 - 1470
Journal Article
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, ISSN 1073-449X, 09/2019, Volume 200, Issue 5, pp. 532 - 534
Consistent with being a transcriptional target of several oncogenic transcription factors (HIF-1α [hypoxia inducible factor], Akt [serine/threonine protein... 
6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE | 6-PHOSPHOFRUCTO-2-KINASE | RESPIRATORY SYSTEM | CRITICAL CARE MEDICINE | Hypertension | Phosphorylation | Pulmonary arteries | Cyclin-dependent kinases | DNA damage | Smooth muscle | Metabolism | Kinases | Proteins | Angiogenesis | Cell growth | Cell cycle | Hypoxia | Deoxyribonucleic acid--DNA | Cancer
Journal Article
Journal Article
Cell, ISSN 0092-8674, 08/2013, Volume 154, Issue 3, pp. 651 - 663
Journal Article