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atherosclerotic lesions (2) 2
biochemistry & molecular biology (2) 2
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cholesterol (2) 2
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FEBS Letters, ISSN 0014-5793, 01/2014, Volume 588, Issue 1, pp. 65 - 70
StAR family proteins in vascular macrophages participate in reverse cholesterol transport (RCT). We hypothesize that under pathophysiological oxidative stress,... 
StAR protein | Oxidative stress | Reverse cholesterol transport | Cholesterol hydroperoxide | Macrophage | 7α-OOH | db-cAMP | 3-(4,5-dimethylthiazolyl-2-yl)-2,5-diphenyltetrazolium bromide | 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethyl-benzimidazolylcarbocyanine iodide | ATP binding cassette transporter A1 | phosphate-buffered saline | MTT | 3β-hydroxycholest-5-ene-7α-hydroperoxide | StarD4 | 1-palmitoyl-2-sn-glycero-3-phosphocholine | dibutyryl-cAMP | POPC | 7α-OH | ChOOH(s) | cholest-5-ene-3β,7α-diol | ABCA1 | PBS | 4,4-difluoro-5-(4-phenyl-1,3-butadienyl)-4-bora-3a,4a-diaza-s-inda-cene-3-undecanoic acid | cholesterol hydroperoxide(s) | small unilamellar vesicle(s) | StarD1 | type-4 steroidogenic acute regulatory domain protein | type-1 steroidogenic acute regulatory domain protein | C11-BODIPY | SUV(s) | JC-1 | ATHEROSCLEROTIC LESIONS | CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | LOW-DENSITY-LIPOPROTEIN | TRAFFICKING | CELL BIOLOGY | EFFLUX | BIOPHYSICS | EFFECTOR ACTION | PROTEINS | EXPRESSION | Oxidative Stress | Membrane Potential, Mitochondrial - drug effects | Phosphoproteins - metabolism | ATP Binding Cassette Transporter 1 - metabolism | Dose-Response Relationship, Drug | RNA Interference | Time Factors | Lipid Peroxidation - drug effects | Biological Transport - drug effects | Cell Membrane - metabolism | Cell Membrane - drug effects | Cell Line | Cell Survival - drug effects | Cholesterol - analogs & derivatives | Mitochondria - metabolism | Macrophages - cytology | Phosphoproteins - genetics | Cholesterol - metabolism | Blotting, Western | Macrophages - metabolism | Animals | Cholesterol - pharmacology | Macrophages - drug effects | Bucladesine - pharmacology | Mice | Macrophages | Cholesterol
Journal Article
FEBS Letters, ISSN 0014-5793, 1999, Volume 462, Issue 1, pp. 113 - 116
Oxidized low density lipoprotein (OxLDL) possesses several proatherogenic characteristics, among which a marked cytotoxicity. In vitro, cytotoxicity of OxLDL... 
5,6-Epoxycholesterol | 7-Ketocholesterol | Stress protein | 7-Hydroperoxycholesterol | 7-Hydroxycholesterol | 25-Hydroxycholesterol | 7α-OOH, 7-α-hydroperoxycholesterol | HUVEC, human umbilical vein endothelial cells | LDL, low density lipoproteins | ECGF, endothelial cell growth factor | hsp(s), heat shock protein(s) | OxLDL, oxidized low density lipoproteins | 25-OH, 25-hydroxycholesterol | 7α-OH, 7-α-hydroxycholesterol | PAGE, polyacrylamide gel electrophoresis | MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide | 7-keto, 7-ketocholesterol | 7β-OH, 7-β-hydroxycholesterol | 5α-OOH, 5-α-hydroperoxycholesterol | FCS, fetal calf serum | 7- Ketocholesterol | ATHEROSCLEROTIC LESIONS | OXIDATION | CHOLESTEROL | BIOCHEMISTRY & MOLECULAR BIOLOGY | LOW-DENSITY-LIPOPROTEIN | 7-hydroxycholesterol | IDENTIFICATION | 5,6-epoxycholesterol | STRESS PROTEINS | CELL BIOLOGY | 25-hydroxycholesterol | 7-hydroperoxycholeslerol | HEAT-SHOCK PROTEIN-70 | BIOPHYSICS | 7-ketocholesterol | stress protein | ATHEROGENICITY | SMOOTH-MUSCLE CELLS | Gene Expression | Oxidation-Reduction | Endothelium, Vascular - metabolism | Humans | Endothelium, Vascular - pathology | Hydroxycholesterols - metabolism | Lipoproteins, LDL - metabolism | In Vitro Techniques | Ketocholesterols - metabolism | Apoptosis | HSP70 Heat-Shock Proteins - biosynthesis
Journal Article
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