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RSC ADVANCES, ISSN 2046-2069, 2019, Volume 9, Issue 12, pp. 6779 - 6784
Fluorescent immunosorbent assay (FIA) is very promising for sensitive and selective analysis in bio-medical applications. Here, we proposed an assay, using... 
SENSOR | METRONIDAZOLE | AMINES | CHEMISTRY, MULTIDISCIPLINARY | 9-AMINOACRIDINE
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 06/2019, Volume 309, Issue C
Structure-guided design of novel pharmacologically active molecules relies at least in part on functionally relevant accuracy of macromolecular structures for... 
Human acetylcholinesterase | Structure-based drug design | Donepezil | Room-temperature X-ray structure | BW284c51 | 9-Aminoacridine
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 10315 - 8
Biomolecule abundance levels change with the environment and enable a living system to adapt to the new conditions. Although, the living system maintains at... 
MATRIX | POPULATION | NETWORKS | MULTIDISCIPLINARY SCIENCES | MASS-SPECTROMETRY | 9-AMINOACRIDINE | Homeostasis | Aging | Lysates | Scaling | Metabolites
Journal Article
Journal of Organometallic Chemistry, ISSN 0022-328X, 10/2019, Volume 897, pp. 42 - 49
Two new platinum(II) complexes incorporating acridine ligands with aniline moieties were successfully synthesised and characterised. The acridine-based ligands... 
Anticancer | Acridine | Platinum | MECHANISM | ANTICANCER AGENTS | CISPLATIN-INDUCED NEPHROTOXICITY | CHEMISTRY, ORGANIC | COORDINATION | CHEMISTRY, INORGANIC & NUCLEAR | PALLADIUM(II) COMPLEXES | IN-VITRO | BIOLOGICAL EVALUATION | LIGAND | DERIVATIVES | 9-AMINOACRIDINE | Aniline | Analysis
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 08/2019, Volume 309, Issue C, pp. 108698 - 108698
Structure-guided design of novel pharmacologically active molecules relies at least in part on functionally relevant accuracy of macromolecular structures for... 
Human acetylcholinesterase | Room-temperature X-ray structure | BW284c51 | Structure-based drug design | Donepezil | 9-Aminoacridine | TORPEDO-CALIFORNICA | COMPLEX | DESIGN | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHARMACOLOGY & PHARMACY | TOXICOLOGY | CHOLINESTERASES | BINDING | Index Medicus
Journal Article
Journal of the Brazilian Chemical Society, ISSN 0103-5053, 12/2017, Volume 28, Issue 12, pp. 2334 - 2340
In this work, we describe the synthesis of a novel 9-aminoacridine derivative that presents surprisingly different colors when exposed to neutral, acidic or... 
PH indicator | 9-aminoacridine derivative | Organic medium | PK(A) VALUES | DYES | organic medium | TITRATIONS | MIXED-SOLVENTS | CHEMISTRY, MULTIDISCIPLINARY | pH indicator | SOLUBILITY | WATER
Journal Article
BBA - Biomembranes, ISSN 0005-2736, 06/2016, Volume 1858, Issue 6, pp. 1362 - 1372
Journal Article
Inorganica Chimica Acta, ISSN 0020-1693, 08/2016, Volume 449, pp. 44 - 51
We report the synthesis and X-ray characterization of an unusual complex formed by pyridine-2,6-dicarboxylic acid N-oxide and Fe exhibiting a rare 1:3... 
Pyridine-2,6-dicarboxylic acid N-oxide | π-Stacking | Supramolecular | 9-Aminoacridine | Proton transfer | DESIGN | CHEMISTRY | pi-Stacking | DERIVATIVES | CHEMISTRY, INORGANIC & NUCLEAR | Alkaloids | Pyridine | Chemical plants | Oxalic acid
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 01/2018, Volume 143, pp. 1028 - 1038
In an attempt to develop effective and safe anticancer agents, we designed, synthesized and examined 23 novel quinacrine (QC) derivatives by combining the... 
Anticancer agents | S phase arrest | Inhibition of DNA replication | 9-Aminoacridine | Cyclins | Hybrid molecules | CELLS | CHEMISTRY, MEDICINAL | MECHANISM | REALITY | ANALOGS | QUINACRINE | MOLECULES | AGENTS | INHIBITORS | CYTOTOXICITY | DERIVATIVES | Cytokinins | DNA replication | Breast cancer | Cell death | Prostate cancer | Protein binding | Index Medicus
Journal Article
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, ISSN 1386-1425, 01/2019, Volume 206, pp. 622 - 629
The fluorescence quenching of Acriflavine (AFN) by certain estrogens was examined in aqueous media by employing steady state and time-resolved fluorescence... 
Antioxidant | AFN | Fluorescence quenching | HYDROGEN ABSTRACTION | ACID | LIPID-PEROXIDATION | ANTIOXIDANTS | MOLECULAR-ORBITAL METHODS | TERT-BUTOXYL | FLUORESCENCE | SPECTROSCOPY | BASIS-SETS | RADICALS | 9-AMINOACRIDINE | Antioxidants | Thermodynamics | Hydrogen | Estrogen | Fluorescence | Investigations | Sugars | Monosaccharides
Journal Article
International Journal of Mass Spectrometry, ISSN 1387-3806, 2012, Volume 310, pp. 72 - 76
► Glycosaminoglycans (GAGs) are acidic polysaccharides – often sulphated. ► Sulphate loss is an important, but unwanted fragmentation in the mass spectra of... 
Hyaluronan | 9-AA (9-aminoacridine) | Chondroitin sulphate/oversulphated chondroitin | Sulphate loss | DHB (2,5-dihydroxybenzoic acid) | MALDI | CHONDROITIN SULFATE | MATRIX | ASSISTED-LASER-DESORPTION/IONIZATION | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | RATIO | SPECTROSCOPY | SPECTROMETRIC ANALYSIS | 9-AMINOACRIDINE | Hyaluronic acid
Journal Article
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, ISSN 1386-1425, 10/2013, Volume 114, pp. 316 - 322
The interaction of acriflavine with uracils was investigated by using spectroscopic tools viz., UV–Vis absorption, steady state and time resolved fluorescence... 
Acriflavine | Uracils | Fluorescence quenching | NUCLEOTIDES | DYE | ACID | FLUORESCENCE | SPECTROSCOPY | DNA | COMPLEXES | 9-AMINOACRIDINE | Pyrimidines
Journal Article
International Journal of Cancer, ISSN 0020-7136, 04/2012, Volume 130, Issue 7, pp. 1660 - 1670
Journal Article
New Journal of Chemistry, ISSN 1144-0546, 11/2012, Volume 36, Issue 11, pp. 2188 - 2191
A facile synthesis of novel antitumor N(9)-methyl-3-(9-acridinylamino)-5-hydroxymethylaniline (AHMA) derivatives is described. Boc protection of aminobenzoic... 
3-(9-ACRIDINYLAMINO)-5-HYDROXYMETHYLANILINE | INVITRO | COMPLEXES | AGENTS | CHLOROQUINE | ACRIDINE-DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY | 9-AMINOACRIDINE
Journal Article
ONCOLOGY LETTERS, ISSN 1792-1074, 11/2016, Volume 12, Issue 5, pp. 4125 - 4132
The present study found that, similarly to 5-fluorouracil, low concentrations (1-10 mu M) of 9-aminoacridine (9-AAA) inhibited the growth of the two rat... 
CANCER-CELLS | SURFACE-PROPERTIES | ANTICANCER AGENTS | apoptosis | 9-AMINOACRIDINE FLUORESCENCE | YEAST-CELLS | 5-fluorouracil | specific inhibition of cancer cell growth | ASPIRATED CELLS | ONCOLOGY | ACRIDINE | 9-aminoacridine | NF-KAPPA-B | DERIVATIVES | CHARGE
Journal Article