X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (1367193) 1367193
Newspaper Article (261318) 261318
Book Review (185831) 185831
Book / eBook (114603) 114603
Publication (113368) 113368
Dissertation (108956) 108956
Report (99677) 99677
Book Chapter (35397) 35397
Newsletter (18159) 18159
Web Resource (11853) 11853
Magazine Article (10111) 10111
Conference Proceeding (7445) 7445
Transcript (6488) 6488
Trade Publication Article (2839) 2839
Government Document (1868) 1868
Paper (1687) 1687
Reference (1549) 1549
Patent (1141) 1141
Data Set (242) 242
Technical Report (129) 129
Electronic Resource (53) 53
Market Research (47) 47
Presentation (15) 15
Streaming Audio (12) 12
Map (11) 11
Journal / eJournal (5) 5
Compact Disc (2) 2
Streaming Video (2) 2
Poem (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (794985) 794985
humans (493412) 493412
animals (330309) 330309
male (252030) 252030
female (242692) 242692
research (170186) 170186
analysis (160319) 160319
capital gains (140360) 140360
mice (124120) 124120
earnings per share (120490) 120490
stockholders (120334) 120334
proteins (118894) 118894
adult (118020) 118020
middle aged (115641) 115641
biochemistry & molecular biology (107527) 107527
stock exchanges (104076) 104076
business metrics (103734) 103734
research article (101028) 101028
gene expression (92946) 92946
present value (91928) 91928
cell biology (91164) 91164
medicine (91123) 91123
physiological aspects (90478) 90478
health aspects (89191) 89191
aged (86715) 86715
stock prices (85885) 85885
corporate profits (82814) 82814
neurosciences (81981) 81981
multidisciplinary sciences (81487) 81487
expression (80576) 80576
studies (80576) 80576
rats (77407) 77407
equity (74971) 74971
genetic aspects (74077) 74077
article (73477) 73477
immunology (71937) 71937
cancer (70426) 70426
oncology (69564) 69564
profit margins (68722) 68722
risk factors (67148) 67148
capital losses (65472) 65472
dividends (65152) 65152
science (64513) 64513
boards of directors (63814) 63814
biology (61091) 61091
care and treatment (58798) 58798
medicine & public health (56688) 56688
pharmacology & pharmacy (56455) 56455
genes (56253) 56253
microbiology (55587) 55587
inflammation (55512) 55512
apoptosis (52391) 52391
rodents (50276) 50276
signal transduction (50259) 50259
physiology (49746) 49746
biochemistry (48700) 48700
endocrinology & metabolism (48171) 48171
life sciences (47829) 47829
abridged index medicus (46004) 46004
genetics (45575) 45575
enzymes (43747) 43747
medical research (42764) 42764
oxidative stress (42688) 42688
cells, cultured (42621) 42621
cells (42298) 42298
gene-expression (41870) 41870
investments (41418) 41418
mutation (41113) 41113
adolescent (41091) 41091
metabolism (40657) 40657
appointments & personnel changes (40646) 40646
activation (40246) 40246
molecular sequence data (40213) 40213
review (39947) 39947
usage (39199) 39199
molecular biology (38774) 38774
in-vitro (38509) 38509
disease (38420) 38420
biotechnology & applied microbiology (38242) 38242
genetics & heredity (38029) 38029
chemistry (37823) 37823
medicine, research & experimental (37337) 37337
diabetes (37163) 37163
brain (36446) 36446
cytokines (36151) 36151
volatility (35526) 35526
diagnosis (35169) 35169
kinases (34760) 34760
development and progression (33834) 33834
amino acid sequence (33189) 33189
alzheimer's disease (32651) 32651
time factors (32596) 32596
return on assets (32106) 32106
mortality (31728) 31728
protein (31724) 31724
disease models, animal (31095) 31095
child (31061) 31061
phosphorylation (31026) 31026
methods (30874) 30874
pathology (30871) 30871
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (36104) 36104
Robarts - Stacks (27819) 27819
UTL at Downsview - May be requested (22610) 22610
UofT at Mississauga - Stacks (7572) 7572
Engineering & Comp. Sci. - Stacks (5848) 5848
UofT at Scarborough - Stacks (5120) 5120
Collection Dvlpm't (Acquisitions) - Vendor file (4405) 4405
Collection Dvlpm't (Acquisitions) - Closed Orders (4179) 4179
OISE - Stacks (3507) 3507
Online Resources - Online (2803) 2803
St. Michael's College (John M. Kelly) - 2nd Floor (2665) 2665
Earth Sciences (Noranda) - Stacks (2108) 2108
Victoria University E.J. Pratt - Stacks (2094) 2094
Royal Ontario Museum - Stacks (1570) 1570
Trinity College (John W Graham) - Stacks (1521) 1521
Pontifical Inst. Mediaeval Studies - Library use only (1054) 1054
Physics - Stacks (1009) 1009
Music - Stacks (872) 872
Trinity College (John W Graham) - Storage (823) 823
Thomas Fisher Rare Book - Rare Book (822) 822
Mathematical Sciences - Stacks (810) 810
Law (Bora Laskin) - Stacks (768) 768
St. Michael's College (John M. Kelly) - 3rd Floor (721) 721
Victoria University E.J. Pratt - Reference (590) 590
New College (Ivey) - Stacks (559) 559
Providence Healthcare - Stacks (549) 549
Astronomy & Astrophysics - Ask at library (516) 516
Aerospace - Stacks (464) 464
Knox College (Caven) - Stacks (452) 452
Scarborough Hospital - General (434) 434
Chemistry (A D Allen) - Stacks (427) 427
Media Commons - Microtexts (407) 407
Faculty of Information - Stacks (372) 372
Gerstein Science - Reference (371) 371
Dentistry (Harry R Abbott) - Stacks (363) 363
Robarts - Reference (356) 356
Trinity College (John W Graham) - Reference (344) 344
Robarts - Storage (334) 334
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (324) 324
Criminology - Stacks (314) 314
Holland Bloorview Kids Rehabilitation - Stacks (312) 312
Victoria University Emmanuel College - Stacks (300) 300
UofT at Mississauga - Reference (296) 296
St. Augustine's Seminary - Stacks (284) 284
Regis College - Stacks (282) 282
Toronto East General Hospital - Stacks (269) 269
UofT at Scarborough - Withdrawn (259) 259
Dentistry (Harry R Abbott) - Withdrawn (250) 250
Victoria University E.J. Pratt - Storage (238) 238
St. Michael's College (John M. Kelly) - Reference (228) 228
University College (Laidlaw) - Stacks (223) 223
Victoria University CRRS - Library use only (223) 223
Royal Ontario Museum - Periodical Stacks (215) 215
Lakeridge Health Sciences - Oshawa (214) 214
Architecture Landscape (Shore + Moffat) - Stacks (213) 213
St. Michael's Hospital - Stacks (201) 201
Scarborough Hospital - Birchmount (196) 196
Indust. Rel's & Hum. Resources (Newman) - Library use only (194) 194
Dentistry (Harry R Abbott) - May be requested in 6-10 wks (191) 191
Engineering & Comp. Sci. - Reference (186) 186
Art - Library use only (181) 181
Credit Valley Hospital - Stacks (173) 173
West Park Healthcare Centre - Stacks (168) 168
Gerstein Science - Circulation Desk (166) 166
Massey College (Robertson Davies) - Rare Book (159) 159
Gerstein Science - Missing (157) 157
Markham Stouffville Hospital - Stacks (156) 156
Humber River Regional Hospital - Church Stacks (154) 154
UofT Schools - Stacks (152) 152
East Asian (Cheng Yu Tung) - Reference (151) 151
OISE - Reference (151) 151
Innis College - Stacks (145) 145
Institute for Christian Studies - Stacks (145) 145
Baycrest Hospital - Stacks (139) 139
Faculty of Information - May be requested in 6-10 wks (136) 136
Humber River Regional Hospital - Finch Stacks (135) 135
OISE - Curriculum Resources (131) 131
Providence Healthcare - Reference (124) 124
Music - Reference (120) 120
Pontifical Inst. Mediaeval Studies - Reference (120) 120
Robarts - May be requested in 6-10 wks (116) 116
Earth Sciences (Noranda) - Reference (113) 113
Engineering & Comp. Sci. - Missing (111) 111
Royal Ontario Museum - Far Eastern (111) 111
Thomas Fisher Rare Book - May be requested at Fisher (111) 111
Engineering & Comp. Sci. - May be requested in 6-10 wks (94) 94
Collection Dvlpm't (Acquisitions) - Cancelled Order (90) 90
OISE - Missing (90) 90
Trinity College (John W Graham) - Wycliffe Storage (86) 86
Stacks (84) 84
Robarts - Course Reserves (83) 83
Robarts - Petro Jacyk (80) 80
St. Augustine's Seminary - Reference (80) 80
Earth Sciences (Noranda) - Missing (77) 77
East Asian (Cheng Yu Tung) - Stacks (77) 77
UofT at Scarborough - May be requested in 6-10 wks (77) 77
Physics - Reference (76) 76
Trillium Health Centre - Stacks (74) 74
Victoria University Emmanuel College - Storage (74) 74
UofT at Mississauga - May be requested in 6-10 wks (72) 72
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (2000126) 2000126
French (20040) 20040
Spanish (12661) 12661
German (8046) 8046
Japanese (3255) 3255
Italian (2502) 2502
Portuguese (2156) 2156
Chinese (1255) 1255
Russian (1236) 1236
Polish (1188) 1188
Latin (871) 871
Czech (769) 769
Dutch (543) 543
Turkish (526) 526
Korean (459) 459
Swedish (455) 455
Hungarian (408) 408
Arabic (344) 344
Croatian (270) 270
Danish (268) 268
Slovenian (232) 232
Slovak (201) 201
Ancient Greek (185) 185
Greek (172) 172
Catalan (165) 165
Hebrew (134) 134
Norwegian (127) 127
Romanian (125) 125
Lithuanian (122) 122
Serbian (79) 79
Hindi (71) 71
Sanskrit (67) 67
Bulgarian (46) 46
Indonesian (34) 34
Bengali (33) 33
Afrikaans (32) 32
Finnish (31) 31
Persian (31) 31
Urdu (30) 30
Icelandic (29) 29
Ukrainian (27) 27
Latvian (26) 26
Bosnian (23) 23
Old English (20) 20
Middle (19) 19
Ndonga (18) 18
Austronesian (17) 17
Malay (17) 17
Irish (16) 16
Panjabi (16) 16
Armenian (13) 13
Estonian (13) 13
Nepali (13) 13
Amharic (12) 12
Tibetan (12) 12
Welsh (12) 12
Tamil (11) 11
Telugu (11) 11
American (10) 10
Aramaic (10) 10
Geez (10) 10
Indian (10) 10
Old Provençal (10) 10
Galician (9) 9
Gujarati (9) 9
Niger-Kordofanian (9) 9
Yiddish (9) 9
Indic (8) 8
Occitan (8) 8
Basque (7) 7
Breton (7) 7
Germanic (7) 7
Old French (7) 7
Quechua (7) 7
Malayalam (6) 6
Old High German (6) 6
Ottoman (6) 6
Romance (6) 6
South (6) 6
Ugaritic (6) 6
Western Frisian (6) 6
Albanian (5) 5
Creole (5) 5
Gaelic (5) 5
High (5) 5
Slavic (5) 5
Sorbian (5) 5
Vietnamese (5) 5
Akkadian (4) 4
Assamese (4) 4
Bhasa (4) 4
Braj (4) 4
Church Slavic (4) 4
Kannada (4) 4
Maori (4) 4
Marathi (4) 4
Mongolian (4) 4
Nepal (4) 4
Romansh (4) 4
Sino-Tibetan (4) 4
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, ISSN 0002-7863, 08/2016, Volume 138, Issue 30, pp. 9663 - 9674
Amyloid-beta (A beta) is a 39-42 residue protein produced by the cleavage of the amyloid precursor protein (APP), which subsequently aggregates to form... 
ANGLE-SPINNING NMR | 3-DIMENSIONAL STRUCTURE | ROTATING SOLIDS | EXPERIMENTAL CONSTRAINTS | SOLID-STATE NMR | SUPRAMOLECULAR STRUCTURE | PROTEIN AGGREGATION | ALZHEIMERS-DISEASE | NUCLEAR-MAGNETIC-RESONANCE | ELECTRON-MICROSCOPY | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 06/2013, Volume 110, Issue 24, pp. 9758 - 9763
The generation of toxic oligomers during the aggregation of the amyloid-beta (A beta) peptide A beta 42 into amyloid fibrils and plaques has emerged as a... 
IMPLIES | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | neurodegeneration | COMMON MECHANISM | POLYMERIZATION | OLIGOMERS | FORMS | molecular mechanisms | chemical kinetics | protein misfolding | CONFORMATIONAL CONVERSION | KINETICS | PROTEINS | Naturvetenskap | Kemi | Physical Chemistry | Fysikalisk kemi | Natural Sciences | Chemical Sciences
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 07/2014, Volume 111, Issue 26, pp. 9384 - 9389
The two major forms of the amyloid-beta (A beta) peptide found in plaques in patients suffering from Alzheimer's disease, A beta 40 and A beta 42, only differ... 
aggregation mechanism | MECHANISM | protein aggregation | rate law | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | AMYLOID-BETA-PEPTIDE | neurodegeneration | OCCURS
Journal Article
BIOPHYSICAL JOURNAL, ISSN 0006-3495, 06/2013, Volume 104, Issue 12, pp. 2714 - 2724
Using homonuclear H-1 NOESY spectra, with chemical shifts, (3)J(H)(H)(N)(alpha) scalar couplings, residual dipolar couplings, and (H-15N)-H-1 NOEs, we have... 
PROTEIN A-BETA | AMYLOID FIBRILS | BIOPHYSICS | UNFOLDED STATE | C-TERMINUS | PEPTIDES A-BETA(1-40) | ALZHEIMERS-DISEASE | ENSEMBLES | SECONDARY STRUCTURE | MOLECULAR-DYNAMICS SIMULATIONS | CONFORMATIONS
Journal Article
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, ISSN 0022-3069, 11/2006, Volume 65, Issue 11, pp. 1040 - 1048
Neuropathologic examination of 3 patients with Alzheimer disease in the Elan Pharmaceuticals trial using antibodies specific for different A beta species... 
ANTIBODIES | CLEARANCE | antibody | AMYLOID DEPOSITION | Alzheimer disease | therapy | ALZHEIMERS-DISEASE | A-BETA-42 IMMUNIZATION | PATHOLOGY | NEUROSCIENCES | PEPTIDE | CLINICAL NEUROLOGY | IMMUNOTHERAPY | immunization | MOUSE MODEL | A beta species | NEUROPATHOLOGY | microglia
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 01/2015, Volume 6
In Alzheimer's disease (AD), beta-amyloid (A beta) plaques are tightly enveloped by microglia processes, but the significance of this phenomenon is unknown.... 
CLEARANCE | AMYLOID-BETA | ALZHEIMERS-DISEASE | DEPOSITION | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | A-BETA | CROSS-LINKING | OLIGOMERS | COGNITIVE DEFICITS | TRANSGENIC MICE
Journal Article
ANNALS OF NEUROLOGY, ISSN 0364-5134, 03/2006, Volume 59, Issue 3, pp. 512 - 519
Objectives. Amyloid-beta(42) (A beta(42)) appears central to Alzheimer's disease (AD) pathogenesis and is a major component of amyloid plaques. Mean... 
ENTORHINAL CORTEX | DEMENTIA | METABOLISM | ALZHEIMERS-DISEASE | MOUSE MODEL | MILD COGNITIVE IMPAIRMENT | APOLIPOPROTEIN-E GENOTYPE | NEUROSCIENCES | PITTSBURGH COMPOUND-B | BRAIN | CLINICAL NEUROLOGY | AGE
Journal Article
JOURNAL OF ALZHEIMERS DISEASE, ISSN 1387-2877, 2017, Volume 55, Issue 2, pp. 813 - 822
Background: Decreased concentrations of amyloid-beta 1-42 (A beta(42)) in cerebrospinal fluid (CSF) and increased retention of A beta tracers in the brain on... 
DEMENTIA | A-BETA-42 | MARKERS | TAU | CSF A-BETA-42/A-BETA-40 | BIOMARKER CHANGES | biomarker | MILD COGNITIVE IMPAIRMENT | NEUROSCIENCES | PITTSBURGH COMPOUND-B | BETA | amyloid-beta | A-BETA-42/A-BETA-40 RATIO | cerebrospinal fluid | positron emission tomography | Alzheimer's disease
Journal Article
EMBO JOURNAL, ISSN 0261-4189, 10/2010, Volume 29, Issue 19, pp. 3408 - 3420
The amyloid peptides A beta(40) and A beta(42) of Alzheimer's disease are thought to contribute differentially to the disease process. Although A beta(42)... 
LONG-TERM | BIOCHEMISTRY & MOLECULAR BIOLOGY | oligomer | TERMINAL FRAGMENT | AMYLOID PRECURSOR PROTEIN | SYNAPTIC PLASTICITY | OLIGOMERS | CELL BIOLOGY | microelectrode array | neurotoxicity | IN-VIVO | MUTATIONS | beta-amyloid peptides | Alzheimer's disease | GAMMA-SECRETASE | MOLECULAR-BASIS | AGGREGATION
Journal Article
BIOCHEMISTRY, ISSN 0006-2960, 07/2015, Volume 54, Issue 27, pp. 4197 - 4207
Soluble oligorners and protofibrils of the A beta 42 peptide are neurotoxic intermediates in the conversion of monomeric A beta 42 into the amyloid fibrils... 
FIBRIL FORMATION | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | AMYLOID-BETA-PEPTIDE | SECONDARY NUCLEATION | SOLUTION NMR | TOXICITY | PROTOFIBRILS | SHEET | OLIGOMERS | AGGREGATION
Journal Article
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, ISSN 0002-7863, 04/2012, Volume 134, Issue 15, pp. 6625 - 6636
Abnormal interactions of Cu and Zn ions with the amyloid beta (A beta) peptide are proposed to play an important role in the pathogenesis of Alzheimer's... 
NADPH OXIDASE | ALZHEIMER A-BETA | A-BETA-42 | AMYLOID-BETA PROTEIN | DISEASE | HIGH-AFFINITY | COPPER | BINDING SITE | ZINC-BINDING | CHEMISTRY, MULTIDISCIPLINARY | OLIGOMERS
Journal Article
BRAIN, ISSN 0006-8950, 09/2013, Volume 136, pp. 2677 - 2696
Inflammatory processes are important in the pathogenesis of Alzheimer's disease and in response to amyloid-beta immunotherapy. We investigated the expression... 
clinical trial | A-BETA IMMUNIZATION | MICROGLIAL ACTIVATION | HUMAN BRAIN | FC-RECEPTORS | REACTIVE MICROGLIA | MACROPHAGE SCAVENGER RECEPTOR | NEUROSCIENCES | CLINICAL NEUROLOGY | innate immunity | immunotherapy | AMYLOID-BETA-PEPTIDE | CENTRAL-NERVOUS-SYSTEM | TRANSGENIC MOUSE MODELS | Alzheimer's disease | microglia | GENOME-WIDE ASSOCIATION
Journal Article
ANNALS OF NEUROLOGY, ISSN 0364-5134, 02/2009, Volume 65, Issue 2, pp. 176 - 183
Objective: For therapies for Alzheimer's disease (AD) to have the greatest impact, it will likely be necessary to treat individuals in the "preclinical"... 
TAU-PROTEIN | ENTORHINAL CORTEX | DEMENTIA | CLINICAL-DIAGNOSIS | PRECLINICAL ALZHEIMER-DISEASE | CSF BIOMARKERS | CEREBRAL ATROPHY | APOLIPOPROTEIN-E GENOTYPE | DIAGNOSTIC-CRITERIA | NEUROSCIENCES | CLINICAL NEUROLOGY | IMPAIRMENT
Journal Article
JOURNAL OF NEUROSCIENCE, ISSN 0270-6474, 12/2010, Volume 30, Issue 50, pp. 17035 - 17040
Identifying high-risk populations is an important component of disease prevention strategies. One approach for identifying at-risk populations for Alzheimer's... 
BRAIN ACTIVITY | DEFAULT-MODE | DEMENTIA | MEMORY | GENETIC RISK | GENOTYPE | ALZHEIMERS-DISEASE | NETWORK FUNCTION | NEUROSCIENCES | APOLIPOPROTEIN-E | BETA
Journal Article
NEUROBIOLOGY OF AGING, ISSN 0197-4580, 02/2015, Volume 36, Issue 2, pp. 877 - 885
Journal Article
Journal of Molecular Medicine, ISSN 0946-2716, 11/2008, Volume 86, Issue 11, pp. 1255 - 1267
Journal Article
BIOCHEMISTRY, ISSN 0006-2960, 12/2014, Volume 53, Issue 50, pp. 7893 - 7903
A beta 42 peptides associate into soluble oligomers and protofibrils in the process of forming the amyloid fibrils associated with Alzheimers disease. The... 
FIBRIL FORMATION | THIOFLAVIN-T | MYELIN BASIC-PROTEIN | ATOMIC-FORCE MICROSCOPY | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | A-BETA | SOLUTION NMR | AMYLOID-BETA-PROTEIN | SECONDARY STRUCTURE | C-TERMINAL FRAGMENTS
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 01/2017, Volume 114, Issue 2, pp. E200 - E208
The aggregation of the 42-residue form of the amyloid-beta peptide (A beta 42) is a pivotal event in Alzheimer's disease (AD). The use of chemical kinetics has... 
DESIGN | MULTIDISCIPLINARY SCIENCES | NEURODEGENERATION | AMYLOID HYPOTHESIS | MECHANISMS | amyloid-beta peptide | PHASE | drug discovery | protein misfolding | protein aggregation | OCCURS | Alzheimer's disease | MODULATION
Journal Article
LANCET, ISSN 0140-6736, 07/2008, Volume 372, Issue 9634, pp. 216 - 223
Background Immunisation of patients with Alzheimer's disease with full-length amyloid-beta peptide (A beta(42)) can clear amyloid plaques from the brain. Our... 
ANTIBODIES | AN1792 | MEDICINE, GENERAL & INTERNAL | DEMENTIA | MEMORY | IMMUNOTHERAPY | AMYLOID-BETA PROTEIN | VACCINATION | A-BETA-42 IMMUNIZATION | PEPTIDE
Journal Article
No results were found for your search.

Cannot display more than 1000 results, please narrow the terms of your search.