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Journal Article
Journal of Immunology, ISSN 0022-1767, 06/2011, Volume 186, Issue 11, pp. 6119 - 6128
Journal Article
Molecular Cell, ISSN 1097-2765, 11/2016, Volume 64, Issue 4, pp. 688 - 703
Covalent DNA-protein crosslinks (DPCs) are toxic DNA lesions that interfere with essential chromatin transactions, such as replication and transcription.... 
DVC1 | progeria | protease | formaldehyde | Spartan | Wss1 | Ruijs-Aalfs syndrome | SPRTN | topoisomerase | DNA-protein crosslinks | DNA repair | hepatocellular carcinoma | GENOMIC INSTABILITY | CELLS | DAMAGE RESPONSE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SPARTAN/C1ORF124 | DVC1 C1ORF124 | FANCONI-ANEMIA | HELICASE | NUCLEOTIDE EXCISION-REPAIR | CELL BIOLOGY | Schizosaccharomyces pombe Proteins - chemistry | Fibroblasts - enzymology | Formaldehyde - chemistry | Caenorhabditis elegans Proteins - chemistry | Humans | Caenorhabditis elegans Proteins - metabolism | Substrate Specificity | Crystallography, X-Ray | DNA-Binding Proteins - metabolism | Schizosaccharomyces - genetics | Cisplatin - chemistry | Ultraviolet Rays | Schizosaccharomyces pombe Proteins - metabolism | Protein Interaction Domains and Motifs | Binding Sites | Amino Acid Sequence | Cell Line | Xeroderma Pigmentosum Group A Protein - metabolism | Cross-Linking Reagents - chemistry | Schizosaccharomyces pombe Proteins - genetics | Protein Structure, Secondary | Caenorhabditis elegans - genetics | Xeroderma Pigmentosum Group A Protein - genetics | Models, Molecular | DNA - metabolism | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | Caenorhabditis elegans - radiation effects | Xeroderma Pigmentosum Group A Protein - chemistry | DNA - genetics | Sequence Homology, Amino Acid | DNA - chemistry | Sequence Alignment | Animals | Caenorhabditis elegans - drug effects | Fibroblasts - radiation effects | DNA Repair | Fibroblasts - drug effects | Protein Binding | Schizosaccharomyces - enzymology | Fibroblasts - cytology | Mice | HeLa Cells | Kinetics | Caenorhabditis elegans Proteins - genetics | Caenorhabditis elegans - enzymology | Ubiquitin | Chromatin | Proteases | DNA | Genetic research | Genetic transcription | Molecular biology | Formaldehyde | Index Medicus | BASIC BIOLOGICAL SCIENCES | protease Ruijs-Aalfs syndrome
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 05/2014, Volume 136, Issue 21, pp. 7771 - 7776
Journal Article
Journal of Immunology, ISSN 0022-1767, 08/2017, Volume 199, Issue 3, pp. 1105 - 1112
Serum amyloid A (SAA) is known as an acute-phase protein and a biomarker for inflammatory diseases. Published studies have shown that SAA possesses... 
FIBRIL FORMATION | CELLS | ARTHRITIS SYNOVIAL TISSUE | IN-VITRO | HUMAN NEUTROPHILS | PROTEIN-COUPLED RECEPTOR | PATHWAY | FORMYL PEPTIDE RECEPTOR | INDUCTION | IMMUNOLOGY | EXPRESSION | Serum Amyloid A Protein - pharmacology | Lipopolysaccharides - administration & dosage | Tumor Necrosis Factor-alpha - genetics | Receptors, Formyl Peptide - immunology | Interleukin-1beta - genetics | Lipopolysaccharides - immunology | Receptors, Formyl Peptide - metabolism | Tumor Necrosis Factor-alpha - immunology | Interleukin-1beta - biosynthesis | Macrophages - immunology | Serum Amyloid A Protein - metabolism | Interleukin-6 - genetics | Signal Transduction | Interleukin-1beta - immunology | Toll-Like Receptor 3 - immunology | Inflammation - immunology | Chemotaxis - drug effects | Serum Amyloid A Protein - immunology | Animals | Serum Amyloid A Protein - chemistry | Interleukin-10 - genetics | Interleukin-6 - immunology | Interleukin-6 - biosynthesis | Toll-Like Receptor 2 - immunology | Interleukin-10 - biosynthesis | Mice | Interleukin-10 - immunology | Tumor Necrosis Factor-alpha - biosynthesis | Phosphorylation | Calcium | Lung | Switches | Inflammatory response | Macrophages | Inflammatory diseases | Lipopolysaccharides | Lethal dose | Interleukin 6 | Proteins | Phagocytes | Proteolysis | Rodents | Toll-like receptors | Amyloid | Bioindicators | Extracellular signal-regulated kinase | MAP kinase | JNK protein | TLR4 protein | Tumor necrosis factor-α | Chemotaxis | Acute phase substances | Injury prevention | Lungs | TLR2 protein | Interleukin 10 | Biomarkers | Infiltration | Amyloidosis | Structure-function relationships | Index Medicus | Abridged Index Medicus
Journal Article
PLoS Medicine, ISSN 1549-1277, 2006, Volume 3, Issue 6, pp. 0884 - 0894
Background Obesity is associated with low-grade chronic inflammation, and serum markers of inflammation are independent risk factors for cardiovascular disease... 
C-REACTIVE PROTEIN | MEDICINE, GENERAL & INTERNAL | HUMAN ADIPOSE-TISSUE | HEART-DISEASE | ACTIVATED RECEPTOR-GAMMA | MESSENGER-RNA EXPRESSION | INSULIN-RESISTANCE | CARDIOVASCULAR-DISEASE | NECROSIS-FACTOR-ALPHA | CORONARY-ARTERY-DISEASE | VASCULAR-DISEASE | Lipolysis - drug effects | Obesity - drug therapy | Serum Amyloid A Protein - pharmacology | Humans | Middle Aged | Male | Serum Amyloid A Protein - genetics | Adipocytes - drug effects | RNA, Messenger - metabolism | Obesity - blood | Inflammation - blood | Dose-Response Relationship, Drug | Adipose Tissue - metabolism | Inflammation - complications | Inflammation - metabolism | Thiazolidinediones - therapeutic use | Female | Biomarkers - metabolism | Hypoglycemic Agents - therapeutic use | Cardiovascular Diseases - etiology | Cell Line | Serum Amyloid A Protein - metabolism | Cardiovascular Diseases - metabolism | Cross-Sectional Studies | Cytokines - metabolism | Obesity - complications | Mice, Inbred C57BL | Risk Factors | Stromal Cells - metabolism | Clinical Trials as Topic | Obesity - metabolism | Animals | Adipocytes - metabolism | Obesity - therapy | Mice | Adipose Tissue - drug effects | Obesity | Metabolic diseases | Inflammation | Cardiovascular diseases | Index Medicus | Immunology | Cardiac Surgery | Nutrition | Immunology and allergy | Diabetes | Cardiology | Metabolism | Endocrinology | Cardiovascular Medicine
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 12/2013, Volume 94, Issue 6, pp. 1309 - 1315
Adenosine signaling augments IL‐10‐induced STAT‐3 dependent gene expression in macrophages, suggesting its role in M2c polarization. The alternatively... 
TIMP‐1 | arginase | alternative activation | Arginase | TIMP-1 | Alternative activation | CELLS | ACTIVATION | RECEPTOR AGONISTS | IL-10 PRODUCTION | NECROSIS-FACTOR-ALPHA | IMMUNOLOGY | CELL BIOLOGY | TIMP-1 PRODUCTION | A(2B) | INFLAMMATION | TNF-ALPHA | HEMATOLOGY | EXPRESSION | Analgesics - pharmacology | Serum Amyloid A Protein - genetics | Receptor, Adenosine A2B - genetics | Interleukin-13 - genetics | Phosphorylation - genetics | Adenosine A2 Receptor Agonists - pharmacology | Serum Amyloid A Protein - biosynthesis | Phosphorylation - immunology | Phosphorylation - drug effects | Interleukin-6 - metabolism | STAT3 Transcription Factor - genetics | Interleukin-6 - genetics | Macrophage Activation - immunology | Arginase - genetics | Signal Transduction - genetics | Adenosine - pharmacology | Interleukin-13 - metabolism | Receptor, Adenosine A2B - metabolism | Mice, Knockout | Interleukin-4 - immunology | Macrophages - metabolism | Signal Transduction - drug effects | Interleukin-10 - genetics | Interleukin-6 - immunology | Mice | STAT3 Transcription Factor - immunology | Tissue Inhibitor of Metalloproteinase-1 - immunology | Interleukin-10 - immunology | Macrophage Activation - genetics | Tissue Inhibitor of Metalloproteinase-1 - biosynthesis | Interleukin-13 - immunology | Arginase - biosynthesis | Analgesics - immunology | Signal Transduction - immunology | Arginase - immunology | Receptor, Adenosine A2B - immunology | Interleukin-10 - metabolism | Interleukin-4 - genetics | Macrophages - immunology | STAT3 Transcription Factor - metabolism | Cell Line | Adenosine - immunology | Interleukin-4 - metabolism | Gene Expression Regulation | Macrophages - cytology | Serum Amyloid A Protein - immunology | Tissue Inhibitor of Metalloproteinase-1 - genetics | Animals | Aminopyridines - pharmacology | Macrophage Activation - drug effects | Index Medicus | Inflammation, Extracellular Mediators, & Effector Molecules
Journal Article
Journal Article
Journal Article
Circulation, ISSN 0009-7322, 06/2006, Volume 113, Issue 22, pp. 2623 - 2629
Background - Data on the natural history of peripheral arterial disease (PAD) are scarce and are focused primarily on clinical symptoms. Using noninvasive... 
Peripheral vascular disease | Lipoproteins | Inflammation | Diabetes mellitus | Smoking | C-REACTIVE PROTEIN | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | ANKLE-BRACHIAL INDEX | diabetes mellitus | AMERICAN-HEART-ASSOCIATION | HEALTH-CARE PROFESSIONALS | peripheral vascular disease | VASCULAR-DISEASE | GENERAL-POPULATION | inflammation | SYSTOLIC PRESSURES | smoking | CARDIOVASCULAR-DISEASE | PLASMA HOMOCYSTEINE | lipoproteins | Smoking - adverse effects | Toes - blood supply | Multivariate Analysis | Predictive Value of Tests | Humans | Middle Aged | Male | Inflammation - complications | Diabetic Angiopathies - physiopathology | Smoking - physiopathology | Ankle - blood supply | Brachial Artery - physiopathology | Female | Lipoprotein(a) - blood | C-Reactive Protein - analysis | Peripheral Vascular Diseases - physiopathology | Risk Factors | Homocysteine - blood | Lipoprotein(a) - physiology | Peripheral Vascular Diseases - blood | C-Reactive Protein - physiology | Disease Progression | Regression Analysis | Diabetes Mellitus - physiopathology | Peripheral Vascular Diseases - etiology | Cholesterol, HDL - blood | Homocysteine - physiology | Aged | Longitudinal Studies | Serum Amyloid A Protein - analysis | Serum Amyloid A Protein - physiology | Inflammation - physiopathology | Index Medicus | Abridged Index Medicus | C-Reactive Protein | Life Sciences | Lipoprotein(a) | Cholesterol, HDL | Peripheral Vascular Diseases | Serum Amyloid A Protein | Diabetes Mellitus | Toes | Ankle | Santé publique et épidémiologie | Brachial Artery | Diabetic Angiopathies | Homocysteine
Journal Article