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life sciences & biomedicine (46) 46
science & technology (46) 46
humans (34) 34
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abc (19) 19
diffuse large b-cell lymphoma (17) 17
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health aspects (5) 5
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leukemias. malignant lymphomas. malignant reticulosis. myelofibrosis (5) 5
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1. Full Text The biological and clinical impact of inhibition of NF‐κB‐initiated apoptosis in diffuse large B cell lymphoma (DLBCL)
by Bavi, Prashant and Uddin, Shahab and Bu, Rong and Ahmed, Maqbool and Abubaker, Jehad and Balde, Valorie and Qadri, Zeeshan and Ajarim, Dahish and Al‐Dayel, Fouad and Hussain, Azhar R and Al‐Kuraya, Khawla S
The Journal of pathology, ISSN 0022-3417, 07/2011, Volume 224, Issue 3, pp. 355 - 366
DLBCL | NF‐κB | activated B cell (ABC) phenotype | tissue microarray | NHL therapy | apoptosis | XIAP | NF-κB | Tissue microarray | Activated B cell (ABC) phenotype | Apoptosis | Pathology | Oncology | Life Sciences & Biomedicine | Science & Technology | Hematologic and hematopoietic diseases | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | Investigative techniques, diagnostic techniques (general aspects) | Medical sciences | Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques | Prognosis | Nitriles - pharmacology | Apoptosis - drug effects | Humans | Middle Aged | Male | NF-kappa B - metabolism | Lymphoma, Large B-Cell, Diffuse - metabolism | Sulfones - pharmacology | Dose-Response Relationship, Drug | Herpesvirus 4, Human - isolation & purification | Lymphocyte Activation - immunology | Caspases - metabolism | Biomarkers, Tumor - metabolism | Lymphoma, Large B-Cell, Diffuse - immunology | Female | Antineoplastic Agents - pharmacology | Tumor Cells, Cultured | Biomarkers, Tumor - antagonists & inhibitors | NF-kappa B - antagonists & inhibitors | Lymphoma, Large B-Cell, Diffuse - pathology | Immunophenotyping | Biomarkers, Tumor - physiology | Down-Regulation - drug effects | Enzyme Activation - drug effects | Lymphoma, Large B-Cell, Diffuse - virology | B-Lymphocytes - immunology | NF-kappa B - physiology | Survival Analysis | Aged | Apoptosis - physiology | Index Medicus
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2. Full Text Antiapoptotic properties of MALT1 protease are associated with redox homeostasis in ABC‐DLBCL cells
by Zhu, Leqing and Tang, Fen and Lei, Zhiwei and Guo, Chengbin and Song, Yueqi and Huang, Junqing and Xia, Xichun
Molecular carcinogenesis, ISSN 0899-1987, 12/2019, Volume 58, Issue 12, pp. 2340 - 2352
apoptosis | GLS1 | MALT1 protease | ABC‐DLBCL | ROS | Biochemistry & Molecular Biology | Oncology | Life Sciences & Biomedicine | Science & Technology | Lymphoma, Large B-Cell, Diffuse - pathology | Oxidation-Reduction | Glutathione - metabolism | Lymphocyte Activation | Proto-Oncogene Proteins c-jun - genetics | Humans | Gene Expression Regulation, Neoplastic | Homeostasis | Apoptosis - genetics | Glutaminase - metabolism | Mitochondria - metabolism | Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein - genetics | Lymphoma, Large B-Cell, Diffuse - metabolism | Proto-Oncogene Proteins c-jun - metabolism | Cell Line, Tumor | Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein - metabolism | B-Lymphocytes - pathology | Lymphoma, Large B-Cell, Diffuse - genetics | B-Lymphocytes - metabolism | Glutaminase - genetics | Translocation | Reactive oxygen species | Mucosa | Oxygen consumption | Lymphoid tissue | Lymphoma | Glutaminase | Nuclear transport | Mitochondria | Bioenergetics | Protease | Metabolic pathways | Protein transport | Glutathione | Apoptosis | Index Medicus
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3. Full Text Comprehensive gene expression profiling and immunohistochemical studies support application of immunophenotypic algorithm for molecular subtype classification in diffuse large B-cell lymphoma: a report from the International DLBCL Rituximab-CHOP Consortium Program Study
by Visco, C and Li, Y and Xu-Monette, Z.Y and Miranda, R.N and Green, T.M and Tzankov, A and Wen, W and Liu, W.M and Kahl, B.S and d'Amore, E.S and Montes-Moreno, S and Dybkaer, K and Chiu, A and Tam, W and Orazi, A and Zu, Y and Bhagat, G and Winter, J.N and Wang, H.Y and O'Neill, S and Dunphy, C.H and Hsi, E.D and Zhao, X.F and Go, R.S and Choi, W.W and Zhou, F and Czader, M and Tong, J and Krieken, J.H. van and Huang, Q and Ai, W and Etzell, J and Ponzoni, M and Ferreri, A.J and Piris, M.A and Moller, M.B and Bueso-Ramos, C.E and Medeiros, L.J and Wu, L and Young, K.H
Leukemia, ISSN 0887-6924, 2012, Volume 26, Issue 9, pp. 2103 - 2113
ABC-DLBCL | diffuse large B-cell lymphoma | BCL6 | GCB-DLBCL | CD10 | FOXP1 | Oncology | Life Sciences & Biomedicine | Hematology | Science & Technology | Hematologic and hematopoietic diseases | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | Medical sciences | Cyclophosphamide - administration & dosage | Prednisone - administration & dosage | Lymphoma, Large B-Cell, Diffuse - drug therapy | Prognosis | Oligonucleotide Array Sequence Analysis | Tissue Array Analysis | Humans | Middle Aged | Antibodies, Monoclonal, Murine-Derived - administration & dosage | Rituximab | Immunophenotyping | Male | Survival Rate | Gene Expression Profiling | Immunoenzyme Techniques | Lymphoma, Large B-Cell, Diffuse - mortality | Algorithms | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Lymphoma, Large B-Cell, Diffuse - classification | Biomarkers, Tumor - metabolism | Vincristine - administration & dosage | Female | Biomarkers, Tumor - genetics | Doxorubicin - administration & dosage | Chemotherapy | Usage | Development and progression | Lymphomas | Genetic aspects | Research | Gene expression | Drug therapy | Health aspects | Cancer | Index Medicus | Diffuse large B-cell lymphoma
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4. Full Text Piperlongumine selectively suppresses ABC-DLBCL through inhibition of NF-κB p65 subunit nuclear import
by Niu, Mingshan and Shen, Yangling and Xu, Xiaoyu and Yao, Yao and Fu, Chunling and Yan, Zhiling and Wu, Qingyun and Cao, Jiang and Sang, Wei and Zeng, Lingyu and Li, Zhenyu and Liu, Xuejiao and Xu, Kailin
Biochemical and biophysical research communications, ISSN 0006-291X, 07/2015, Volume 462, Issue 4, pp. 326 - 331
NF-κB | Piperlongumine | ABC-DLBCL | Nuclear import | p65 | P65 | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Nucleus - metabolism | Dioxolanes - pharmacology | Lymphoma, Large B-Cell, Diffuse - pathology | Transcription Factor RelA - antagonists & inhibitors | Transcription Factor RelA - metabolism | Humans | Cell Line, Tumor | Lymphoma, Large B-Cell, Diffuse - metabolism | Mutation | Transcription Factor RelA - genetics | Protein Transport | Index Medicus | ANIMALS | LYMPHOMAS | APOPTOSIS | INHIBITION | THERAPY | SPECIFICITY | DOSES | GENES | CELL PROLIFERATION | CURRENTS | MUTATIONS | 60 APPLIED LIFE SCIENCES
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5. Full Text Assessing IRAK4 Functions in ABC DLBCL by IRAK4 Kinase Inhibition and Protein Degradation
by Zhang, Jing and Fu, Liqiang and Shen, Bin and Liu, Yingtao and Wang, Wenqian and Cai, Xin and Kong, Linglong and Yan, Yilin and Meng, Ryan and Zhang, Zhuming and Chen, Ying-Nan P and Liu, Qian and Wan, Zhao-Kui and Zhou, Tianyuan and Wang, Xiaotao and Gavine, Paul and Del Rosario, Amanda and Ahn, Kay and Philippar, Ulrike and Attar, Ricardo and Yang, Jennifer and Xu, Yanping and Edwards, James P and Dai, Xuedong
Cell chemical biology, ISSN 2451-9456, 12/2020, Volume 27, Issue 12, pp. 1500 - 1509.e13
selective IRAK4 degrader | myeloid differentiation primary response 88 signaling | IRAK4 PROTAC | PROTAC | activated B-cell-like diffuse large B cell lymphoma | interleukin-1 receptor activated kinase 4 (IRAK4) | scaffolding activity of IRAK4 | ABC DLBCL | MyD88 | proteolysis-targeting chimera
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6. Full Text Immunohistochemical distinction of ABC and GCB in extranodal DLBCL is not reflected in mutation patterns
by Hallas, Cora and Preukschas, Michael and Tiemann, Markus
Leukemia research, ISSN 0145-2126, 01/2019, Volume 76, pp. 107 - 111
MYD88 mutations | CARD11 mutations | DLBCL | CD79A/B mutations | Activated B cell-like (ABC) | Immunohistochemistry classifier (Visco-Young) | Extranodal lymphomas | Germinal center B cell-like (GCB) | Oncology | Life Sciences & Biomedicine | Hematology | Science & Technology | Index Medicus
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7. Full Text CCND2 mRNA Expression Is Correlated With R-CHOP Treatment Efficacy and Prognosis in Patients With ABC-DLBCL
by Wang, Di and Zhang, Yue and Che, Yi-Qun
Frontiers in oncology, ISSN 2234-943X, 07/2020, Volume 10, pp. 1180 - 1180
Life Sciences & Biomedicine | Oncology | Science & Technology | Antimitotic agents | Messenger RNA | Gene expression | Antineoplastic agents | overall survival | RNA in situ hybridization | ABC-DLBCL | CCND2 | progression-free survival
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8. Full Text Gene Expression Profiling Reveals Clear Differences Between EBV‐Positive and EBV‐Negative Posttransplant Lymphoproliferative Disorders
by Morscio, J and Dierickx, D and Ferreiro, J. F and Herreman, A and Van Loo, P and Bittoun, E and Verhoef, G and Matthys, P and Cools, J and Wlodarska, I and De Wolf‐Peeters, C and Sagaert, X and Tousseyn, T
American journal of transplantation, ISSN 1600-6135, 05/2013, Volume 13, Issue 5, pp. 1305 - 1316
ABC | DLBCL | GCB | lymphomagenesis | posttransplantation lymphoproliferative disorder | monomorphic PTLD | microarray | organ transplantation | IC‐DLBCL | EBV | immunodeficiency | lymphoid neoplasia | PT‐DLBCL | gene expression profiling | PT-DLBCL | IC-DLBCL | Transplantation | Life Sciences & Biomedicine | Surgery | Science & Technology | Hematologic and hematopoietic diseases | Infectious diseases | Viral diseases | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | Medical sciences | Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases | Herpesvirus 4, Human - genetics | Follow-Up Studies | Virus Latency | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Child, Preschool | Lymphoproliferative Disorders - complications | Male | Organ Transplantation | Lymphoproliferative Disorders - metabolism | Young Adult | In Situ Hybridization | Aged, 80 and over | Epstein-Barr Virus Infections - genetics | Adult | Female | Retrospective Studies | Child | Viral Proteins - biosynthesis | Epstein-Barr Virus Infections - virology | Viral Proteins - genetics | Gene Expression Profiling - methods | Lymphoproliferative Disorders - genetics | Adolescent | Epstein-Barr Virus Infections - complications | Aged | Analysis | Genes | Genetic research | Lymphomas | T cells | Gene expression | Health aspects | Index Medicus
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9. Full Text Should We Use Cell of Origin and Dual-protein Expression in Treating DLBCL?
by Riedell, Peter A and Smith, Sonali M
Clinical lymphoma, myeloma and leukemia, ISSN 2152-2650, 02/2018, Volume 18, Issue 2, pp. 91 - 97
Dual-protein expression DLBCL | ABC | NHL | Non-GCB | GCB | Diffuse large B-cell lymphoma | Oncology | Life Sciences & Biomedicine | Hematology | Science & Technology | Translocation, Genetic | Lymphoma, Large B-Cell, Diffuse - drug therapy | Prognosis | Outcome Assessment (Health Care) | Humans | Gene Expression Profiling | Lymphoma, Large B-Cell, Diffuse - metabolism | Proto-Oncogene Proteins c-myc - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Proto-Oncogene Proteins c-myc - genetics | Lymphoma, Large B-Cell, Diffuse - genetics | Proto-Oncogene Proteins c-bcl-2 - genetics | B-Lymphocytes - metabolism | Index Medicus
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10. Full Text A Dual TLR7/TLR9 Inhibitor HJ901 Inhibits ABC-DLBCL Expressing the MyD88 L265P Mutation
by An, Beiying and Zhu, Shan and Li, Tete and Wu, Jing and Zang, Guoxia and Lv, Xinping and Qiao, Yuan and Huang, Jing and Shao, Yan and Cui, Jiuwei and Liu, Yong-Jun and Chen, Jingtao
Frontiers in cell and developmental biology, ISSN 2296-634X, 04/2020, Volume 8, pp. 262 - 262
Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Cell death | Genetic aspects | MyD88 mutation | TLR9 | signaling pathway | ABC DLBCL | TLR7 | antagonist
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11. Full Text Novel drug targets for personalized precision medicine in relapsed/refractory diffuse large B-cell lymphoma: A comprehensive review
by Camicia, Rosalba and Winkler, Hans C and Hassa, Paul O
Molecular cancer, ISSN 1476-4598, 12/2015, Volume 14, Issue 1, pp. 207 - 207
DLBCL | ABC-DLBCL | DTX3L | STAT1 | CAR-T cells | Chemoresistance | STAT3 | PARP | GCB-DLBCL | Antibody drug conjugate | BCR | NF-ΚB | Macrodomain | ADP-ribosylation | ARTD | Biochemistry & Molecular Biology | Oncology | Life Sciences & Biomedicine | Science & Technology | Animals | Lymphoma, Large B-Cell, Diffuse - drug therapy | Lymphoma, Large B-Cell, Diffuse - pathology | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Humans | Immunotherapy | Neoplasm Recurrence, Local - drug therapy | Drug Resistance, Neoplasm | Molecular Targeted Therapy | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Precision Medicine | Phosphates | Ubiquitin | Biological products | Genes | Mortality | Development and progression | Non-Hodgkin's lymphomas | B cells | Transforming growth factors | Gene expression | T cells | Chemotherapy | Ligases | Health aspects | Cancer | Index Medicus
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